Kinetics and metabolism of fomepizole in healthy humans

Clinical Toxicology

Volumn 50, Issue 5, 2012, Pages 375-383

  McMartin, Kenneth E ^a   Sebastian, C Simon ^a   Dies, David ^b   Jacobsen, Dag ^a,c  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b Louisiana State University School of Medicine Shreveport   (United States)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

4 Carboxypyrazole; 4 Methylpyrazole; Cytochrome P 450; Induction

Indexed keywords

4 METHYLPYRAZOLE; ANTIDOTE; CYTOCHROME P450; DRUG METABOLITE; PLACEBO;

ADULT; ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG METABOLISM; HUMAN; HUMAN EXPERIMENT; LOADING DRUG DOSE; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; URINARY EXCRETION;

ADMINISTRATION, ORAL; ADULT; ANTIDOTES; CROSS-OVER STUDIES; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; ENZYME INDUCTION; HALF-LIFE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; NONLINEAR DYNAMICS; PYRAZOLES; TIME FACTORS; YOUNG ADULT;

EID: 84861057470     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2012.683197     Document Type: Article

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