Overexpression of fibulin-5 in retinal pigment epithelial cells inhibits cell proliferation and migration and downregulates VEGF, CXCR4, and TGFB1 expression in cocultured choroidal endothelial cells

Current Eye Research

Volumn 37, Issue 6, 2012, Pages 540-548

  Li, Fuliang ^a   Xu, Haiwei ^a   Zeng, Yuxiao ^a   Yin, Zheng Qin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Age related macular degeneration; Choroidal endothelial cells; Choroidal neovascularization; Fibulin 5; Retinal pigment epithelium

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; FIBULIN 5; LENTIVIRUS VECTOR; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL MIGRATION; CELL PROLIFERATION; CHOROID; CHOROIDAL ENDOTHELIAL CELL; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; IN VITRO STUDY; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA MACULA AGE RELATED DEGENERATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; CHOROID; COCULTURE TECHNIQUES; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; GENETIC VECTORS; MACACA MULATTA; RATS; RATS, LONG-EVANS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CXCR4; RECOMBINANT PROTEINS; RETINAL PIGMENT EPITHELIUM; RNA, MESSENGER; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84861032487     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2012.665561     Document Type: Article

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