Sustained release of ibuprofen from polymeric micelles with a high loading capacity of ibuprofen in media simulating gastrointestinal tract fluids

Reactive and Functional Polymers

Volumn 72, Issue 6, 2012, Pages 359-364

  Zhang, Yong ^a   Chen, Jiajia ^a   Zhang, Genghui ^a   Lu, Jiawei ^a   Yan, Husheng ^a   Liu, Keliang ^b  

^a NANKAI UNIVERSITY   (China)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Drug delivery; Ibuprofen; pH responsive; Polymeric micelles; Sustained release

Indexed keywords

AMPHIPHILIC DIBLOCK COPOLYMERS; CARBOXYLIC GROUP; ETHYL METHACRYLATES; GASTRIC FLUIDS; GASTROINTESTINAL TRACT; HIGH LOADINGS; HYDROPHILIC BLOCKS; HYDROPHOBIC BLOCKS; HYDROPHOBIC EFFECT; HYDROPHOBIC MOIETIES; IBUPROFEN; INTESTINAL FLUID; IONIC INTERACTION; LOADING CAPACITIES; MODEL DRUGS; N-BUTYL METHACRYLATE; ORAL ADMINISTRATION; PH-RESPONSIVE; POLYMERIC MICELLE; RANDOM COPOLYMER; SUSTAINED RELEASE;

ATOM TRANSFER RADICAL POLYMERIZATION; BLOCK COPOLYMERS; DRUG DELIVERY; DRUG INTERACTIONS; HYDROPHOBICITY; LOADING; MICELLES; POLYETHYLENE GLYCOLS; POLYMERS; STYRENE;

DRUG PRODUCTS;

EID: 84861026337     PISSN: 13815148     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reactfunctpolym.2012.03.010     Document Type: Article

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