Synthesis and evaluation of pH and thermosensitive pectin-based superabsorbent hydrogel for oral drug delivery systems

Starch/Staerke

Volumn 61, Issue 3-4, 2009, Pages 161-172

  Pourjavadi, Ali ^a   Barzegar, Shahram ^a  

^a SHARIF UNIVERSITY OF TECHNOLOGY   (Iran)

Author keywords

2 acrylamido 2 methylpropanesulfonic acid; Acrylic acid; Drug delivery system; Pectin; Superabsorbent

Indexed keywords

2-ACRYLAMIDO-2-METHYLPROPANESULFONIC ACID; ACRYLIC ACID; DRUG DELIVERY SYSTEM; PECTIN; SUPERABSORBENT;

CARBOXYLIC ACIDS; CROSSLINKING; DRUG DELIVERY; FOURIER TRANSFORMS; HYDROGELS; IONIC STRENGTH; LEAKAGE (FLUID); LITHIUM BATTERIES; ORGANIC ACIDS; ORGANIC POLYMERS; POLYSACCHARIDES; SCANNING ELECTRON MICROSCOPY;

PH EFFECTS;

EID: 65349091945     PISSN: 00389056     EISSN: 1521379X     Source Type: Journal    
DOI: 10.1002/star.200800063     Document Type: Article

References (39)

1. M. Mahkam, L. Doostie, S. O. R. Siadat: Synthesis and characterization of acrylic type hydrogels containing azo derivatives of 5-amino salicylic acid for colon-specific drug delivery. Inflammopharmacology 2006, 14, 72-75.
2. M. Mahkam, M. Allahverdipoor: Controlled release of biomolecules from pH-sensitive network polymers prepared by radiation polymerization. Drug Targeting 2004, 12, 151-156.
3. A. Pourjavadi, Sh. Barzegar, F. Zeidabadi: Synthesis and properties of biodegradable hydrogels of k-carrageenan grafted acrylic acid-co-2-acrylamido-2- methylpropanesulfonic acid as candidates for drug delivery systems. React. Funct. Polym. 2007,67, 644-654.
4. A. Pourjavadi, Sh. Barzegar, G. R. Mahdavinia: MBA-crosslinked Na-Alg/CMC as a smart full-polysaccharide superabsorbent hydrogels. Carbohydr. Polym. 2006, 66, 386-395.
5. A. Pourjavadi, R. Soleyman, G. R. Barajee: Novel nanoporous superabsorbent hydrogel based on poly(acrylic acid) grafted onto salep: synthesis and swelling behavior. Starch/ Stärke 2008, 60, 467-475.
6. V. D. Athawale, V. Lele: Recent trends in hydrogels based on starch-graft-acrylic acid: A review. Starch/Stärke 2001, 53, 7-13.
7. V. D. Athawale, V. Lele: Thermal studies on granular maize starch and its graft copolymers with vinyl monomers, Starch/Stärke 2000, 52, 205-213.
8. A. Pourjavadi, M. J. Zohuriaan-Mehr: Modification of carbohydrate polymers via grafting in air. 1. ceric-induced synthesis of starch-g- polyacrylonitrile in presence and absence of oxygen. Starch/Stärke 2002, 54, 140-147.
9. A. Pourjavadi, M. J. Zohuriaan-Mehr: Modification of carbohydrate polymers via grafting in air. 2. Ceric-initiated graft copolymerization of acrylonitrile onto natural and modified polysaccharides. Starch/Stä rke 2002, 54, 482-488.
10. H. Omidian, J. G. Rocca, K. Park: Advances in superporous hydrogels. J. Controlled Release 2005, 102, 3-12.
11. W. E. Hennink, C. F. Nostrum: Novel crosslinking methods to design hydrogels. Adv. Drug Delivery Rev. 2002, 54, 13-36.
12. S. V. Vinogradov, T. K. Bronich, A. V. Kabanov: Nanosized cationic hydrogels for drug delivery: preparation, properties and interactions with cells. Adv. Drug Delivery Rev. 2002 54, 135-147.
13. M. J. Rathborne, M. S. Roberts, J. Hadgraft: Release drug delivery technology, drugs and the pharmaceutical sciences, a series of textbooks and monographs, Marcel Dekker, New York, 2003, chap. 19, 235-236.
14. B. Werner, H. Bu, A. L. Kjøniksen, S. A. Sande, B. Nyström: Characterization of gelation of aqueous pectin via the Ugi multicomponent condensation reaction. Polym. Bull. 2006, 56, 579-589.
15. R. J. Flanagan: Guidelines for the interpretation of analytical toxicology results and unit measurement conversion. Ann. Clin. Biochem. 1998, 35, 261-267.
16. S. M. Halpern, R. Fitzpatrick, G. N. Volans: Ibuprofen toxicity. A review of adverse reactions and overdoses. Adverse Drug React. Toxicol. Rev. 1993, 12, 107-128.
17. H. T. Le, G. M. Bosse, Y. Tsai: Ibuprofen overdoses complicated by renal failure, adult respiratory distress syndrome, and metabolic acidosis. J. Toxicol. Clin. Toxicol. 1994, 32, 315-320.
18. S. A. Seifert, A. C. Bronstein, T. McGuire: Massive ibuprofen ingestion with survival. Clin. Toxicol. 2000, 38, 55-57.
19. G. A. McDonald, T. D. Du Bose Jr, D. A. Molony, R. Verani: Nephrotoxicity of non-steroidal anti-inflammatory drugs. Lancet North Am. Ed. 1994, 44, 515-519.
20. N. A. Peppas, Y. Huang, M. Torres-Lugo, J. H. Ward, J. Zhang: Physicochemical foundations and structural design of hydrogels in medicine and biology. Annu. Rev. Biomed. Eng. 2000, 2, 9-29.
21. N. A. Peppas, P. Bures, W. Leobandung, H. Ichikawa: Hydrogels in pharmaceutical formulations. Eur. J. Pharmaceut. Biopharm. 2000, 50, 27-46.
22. S. K. Bajpai, S. Johnson: Superabsorbent hydrogels for removal of divalent toxic ions. Part I: Synthesis and swelling characterization. React. Funct. Polym. 2005, 62, 271-283.
23. S. K. Bajpai, S. Dubey: In vitro dissolution studies for release of vitamin B12 from poly(N-vinyl-2-pyrrolidone-co-acrylic acid) hydrogels. React. Funct. Polym. 2005, 62, 93-104.
24. A. Pourjavadi, H. Hosseinzadeh, R. Mazidi: Modified carrageenan. 4. Synthesis and swelling behavior of crosslinked k-C-g-AMPS superabsorbent hydrogel with antisalt and pHresponsiveness properties J. Appl. Polym. Sci. 2005, 98, 255-263.
25. N. A. Peppas, E. W. Merrill: Crosslinked poly(vinyl alcohol) hydrogels as swollen elastic networks. J. Appl. Polym. Sci. 1977, 21, 1763-1770.
26. T. Çaykara, E. Turan: Effect of the amount and type of the crosslinker on the swelling behavior of temperature-sensitive poly (N-tert-butylacrylamide-co-acrylamide) hydrogels. Colloid Polym Sci. 2006, 284, 1038-1048.
27. C. Uzun, M. Hassnisaber, M. Sen, O. Guven: Enhancement and control of cross-linking of dimethylaminoethyl methacrylate irradiated at low dose rate in the presence of ethylene glycol dimethacrylate. Nuclear Instruments and Methods in Physics Research B208, 2003, 242-246.
28. H. Omidian, S. A. Hashemi, P. G. Sammes, I. G. Meldrum: A model for the swelling of superabsorbent polymers. Polymer 1998, 39, 6697-6704.
29. H. Omidian, S. A. Hashemi, P. G. Sammes, I. G. Meldrum: Modified acrylic-based superabsorbent polymers (dependence on particle size and salinity). Polymer 1999, 40, 1753-1761.
30. A. R. Berens, H. B. Hopfenberg: Diffusion and relaxation in glassy polymer powders: 2. Separation of diffusion and relaxation parameters. Polymer 1978, 19, 489-496.
31. M. Torres-Lugo, N. A. Peppas: Molecular design and in vitro studies of novel pH-sensitive hydrogels for the oral delivery of calcitonin. Macromolecules 2000, 32, 6646-6651. ogels. React. Funct. Polym. 2005, 62, 93-104.
32. M. P. Mullarney, T. A. P. Seery, R. A. Weiss: Drug diffusion in hydrophobically modified N, N-dimethylacrylamide hydrogels. Polymer 2006, 47, 3845-3855.
33. H. F. Mark: Encyclopedia of Polymer Science and Technology. Controlled release formulation, agricultural, Vol. 9, 3rd. ed., Wiley-Interscience, New York, 2004, 372-393.
34. W. Xue, S. Champ, M. B. Huglin: New superabsorbent thermoreversible hydrogels. Polymer 2001, 42, 2247-2250.
35. R. A. Gemeinhart, H. Park, K. Park: Pore structure of superporous hydrogels. Polym. Adv. Technol. 2000, 11, 617-625.
36. M. Mahkam, N. Sharifi-Sanjani: Preparation of new biodegradable polyurethanes as a therapeutic agent. Polym. Degrad. Stab. 2003, 80, 199-202.
37. M. Mahkam, R. Mohammadi, M. G. Assadi, S. O. Ranaei-Siadat, M. Barshan, S. E. Ranaei-Siadat: Synthesis and characterization of new cross-linked terpolymer systems containing silyl group. Silicon Chem. 2006, 3, 51-56.
38. M. Mahkam, R. Mohammadi, S. O. Ranaei-Siadat: Synthesis and evaluation of biocompatible pH-sensitive hydrogels as colon-specific drug delivery systems. J. Chin. Chem. Soc. 2006, 53, 727-733.
39. V. R. Babu, K. S. V. Krishna Rao, M. Sairam, B. V. K. Naidu, K. M. Hosamani, T. M. Aminabhavi: pH Sensitive interpenetrating network microgels of sodium alginate-acrylic acid for the controlled release of ibuprofen. J. Appl. Polym. Sci. 2006, 99, 2671-2678. 173-187