Maspin expression is a favorable prognostic factor in non-small cell lung cancer

Analytical and Quantitative Cytology and Histology

Volumn 34, Issue 2, 2012, Pages 72-78

  Berardi, Rossana ^a   Santinelli, Alfredo ^a   Onofri, Azzurra ^a   Brunelli, Alessandro ^a   Pierantoni, Chiara ^a   Pisa, Eleonora ^a   Pagliacci, Alessandra ^a   Stramazzotti, Daniela ^a   Zuccatosta, Lina ^a   Mazzanti, Paola ^a   Sabbatini, Armando ^a   Gasparini, Stefano ^a   Bearzi, Italo ^a   Cascinu, Stefano ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

Maspin; Non small cell lung cancer; Prognostic factor

Indexed keywords

MASPIN;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL CARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; SMOKING; UNDIFFERENTIATED CARCINOMA;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BIOPSY; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROGNOSIS; RETROSPECTIVE STUDIES; SERPINS; TUMOR MARKERS, BIOLOGICAL;

EID: 84861009822     PISSN: 08846812     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D: Global cancer statistics. CA Cancer J Clin 2011;61:69-90
2. Capewell S, Sudlow M: Performance and prognosis in patients with lung cancer. Thorax 1990;45:951-956
3. Naruke T, Goya T, Tsuchiya R, Suemasu K: Prognosis and survival in resected lung carcinoma based on the new international staging system. J Thorac Cardiovasc Surg 1988;96: 440-447
4. Van Raemdonck DE, Schneider A, Ginsberg RJ: Surgical treatment for higher stage non-small cell lung carcinoma. Ann Thorac Surg 1992;54:999-1013
5. Zou Z, Anisowicz A, Hendrix MJ, Thor A, Neveu M, Sheng S, Rafidi K, Seftor E, Sager R: Maspin, a serpin with tumorsuppressing activity in human mammary epithelial cells. Science 1994;263:526-529
6. Seftor RE, Seftor EA, Sheng S, Pemberton PA, Sager R, Hendrix MJ: Maspin suppresses the invasive phenotype of human breast carcinoma. Cancer Res 1998;58:5681-5685
7. Shi HY, Zhang W, Liang R, Abraham S, Kittrell FS, Medina D, Zhang M: Blocking tumor growth, invasion and metastasis by maspin in a syngeneic breast cancer model. Cancer Res 2001;61:6945-6951
8. Zhang M, Sheng S, Maas N, Sager R: Maspin: the mouse homolog of a human tumor suppressor gene inhibits mammary tumor invasion and motility. Mol Med 1997;3:49-59
9. Zhang M, Volpert O, Shi YH, Bouck N: Maspin is an angiogenesis inhibitor. Nat Med 2000;6:196-199
10. Beecken WD, Kramer W, Jonas D: New molecular mediators in tumor angiogenesis. J Cell Mol Med 2000;4:262-269
11. Latha K, Zhang W, Cella N, Shi HY, Zhang M: Maspin mediates increased tumor cell apoptosis upon induction of the mitochondrial permeability transition. Mol Cell Biol 2005; 25:1737-1748
12. Biliran H Jr, Sheng S: Pleiotrophic inhibition of pericellular urokinase-type plasminogen activator system by endogenous tumor suppressive maspin. Cancer Res 2001;61:8676-8682
13. Blacque OE, Worrall DM: Evidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagen. J Biol Chem 2002;277:10783-10788
14. Frey A, Soubani AO, Adam AK, Sheng S, Pass HI, Lonardo F: Nuclear, compared with combined nuclear and cytoplasmic expression of maspin, is linked in lung adenocarcinoma to reduced VEGF-A levels and in Stage I, improved survival. Histopathology 2009;54:590-597
15. Nakagawa M, Katakura H, Adachi M, Takenaka K, Yanagihara K, Otake Y, Wada H, Tanaka F: Maspin expression and its clinical significance in non-small cell lung cancer. Ann Surg Oncol 2006;13:1517-1523
16. Takanami I, Abiko T, Koizumi S: Expression of maspin in non-small-cell lung cancer: Correlation with clinical features. Clin Lung Cancer 2008;9:361-366
17. Mountain CF: Revisions in the international system for staging lung cancer. Chest 1997;111:1710-1717
18. Sheng S: A role of novel serpin maspin in tumor progression: The divergence revealed through efforts to converge. J Cell Physiol 2006;209:631-635
19. Lonardo F, Li X, Kaplun K, Soubani A, Sethi S, Gadgeel S, Sheng S: The natural tumor suppressor protein maspin and potential application in non small cell lung cancer. Curr Pharm Des 2010;16:1877-1881
20. Nakashima M, Ohike N, Nagasaki K, Adachi M, Morohoshi T: Prognostic significance of the maspin tumor suppressor gene in pulmonary adenocarcinoma. J Cancer Res Clin Oncol 2004;130:475-479
21. Lonardo F, Li X, Siddiq F, Singh R, Al-Abbadi M, Pass HI, Sheng S: Maspin nuclear localization is linked to favorable morphological features in pulmonary adenocarcinoma. Lung Cancer 2006;51:31-39
22. Hirai K, Koizumi K, Haraguchi S, Hirata T, Mikami I, Fukushima M, Yamagishi S, Kawashima T, Okada D, Shimizu K, Kawamoto M: Prognostic significance of the tumor suppressor gene maspin in non-small cell lung cancer. Ann Thorac Surg 2005;79:248-253
23. Pierson CR, McGowen R, Grignon D, Sakr W, Dey J, Sheng S: Maspin is up-regulated in premalignant prostate epithelia. Prostate 2002;53:255-262
24. Umekita Y, Ohi Y, Souda M, Rai Y, Sagara Y, Sagara Y, Tamada S, Tanimoto A: Maspin expression is frequent and correlates with basal markers in triple-negative breast cancer. Diagn Pathol 2011;6:1-4
25. Smith SL, Watson SG, Ratschiller D, Gugger M, Betticher DC, Heighway J: Maspin-the most commonly expressed gene of the 18q21.3 serpin cluster in lung cancer-is strongly expressed in preneoplastic bronchial lesions. Oncogene 2003;22:8677-8687
26. Katakura H, Takenaka K, Nakagawa M, Sonobe M, Adachi M, Ito S, Wada H, Tanaka F: Maspin gene expression is a significant prognostic factor in resected non-small cell lung cancer (NSCLC): Maspin in NSCLC. Lung Cancer 2006;51:323-328
27. Woenckhaus M, Bubendorf L, Dalquen P, Foerster J, Blaszyk H, Mirlacher M, Soler M, Dietmaier W, Sauter G, Hartmann A, Wild PJ: Nuclear and cytoplasmic Maspin expression in primary non-small cell lung cancer. J Clin Pathol 2007;60: 483-486