메뉴 건너뛰기




Volumn 7, Issue 5, 2012, Pages

Distinct RGK GTPases differentially use α1- and auxiliary β-binding-dependent mechanisms to inhibit CaV1.2/CaV2.2 channels

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL N TYPE; GUANOSINE TRIPHOSPHATASE; RAD REM REM2 GEM PROTEIN; RAS PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VOLTAGE ACTIVATED CALCIUM CHANNEL 1.2; VOLTAGE ACTIVATED CALCIUM CHANNEL 2.2; CACNA1B PROTEIN, HUMAN; CALCIUM CHANNEL L TYPE; L TYPE CALCIUM CHANNEL ALPHA(1C); L-TYPE CALCIUM CHANNEL ALPHA(1C); MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84860997198     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037079     Document Type: Article
Times cited : (52)

References (40)
  • 1
    • 52049098700 scopus 로고    scopus 로고
    • Calcium channel regulation and presynaptic plasticity
    • Catterall WA, Few AP, (2008) Calcium channel regulation and presynaptic plasticity. Neuron 59: 882-901.
    • (2008) Neuron , vol.59 , pp. 882-901
    • Catterall, W.A.1    Few, A.P.2
  • 2
    • 0034518423 scopus 로고    scopus 로고
    • Structure and regulation of voltage-gated Ca2+ channels
    • Catterall WA, (2000) Structure and regulation of voltage-gated Ca2+ channels. Annu Rev Cell Dev Biol 16: 521-555.
    • (2000) Annu Rev Cell Dev Biol , vol.16 , pp. 521-555
    • Catterall, W.A.1
  • 3
    • 33750181953 scopus 로고    scopus 로고
    • Presynaptic Ca2+ channels-integration centers for neuronal signaling pathways
    • Evans RM, Zamponi GW, (2006) Presynaptic Ca2+ channels-integration centers for neuronal signaling pathways. Trends Neurosci 29: 617-624.
    • (2006) Trends Neurosci , vol.29 , pp. 617-624
    • Evans, R.M.1    Zamponi, G.W.2
  • 4
    • 34249049430 scopus 로고    scopus 로고
    • Calcium channel antagonists: clinical uses-past, present and future
    • Triggle DJ, (2007) Calcium channel antagonists: clinical uses-past, present and future. Biochem Pharmacol 74: 1-9.
    • (2007) Biochem Pharmacol , vol.74 , pp. 1-9
    • Triggle, D.J.1
  • 5
    • 0037342572 scopus 로고    scopus 로고
    • Pharmacological modulators of voltage-gated calcium channels and their therapeutical application
    • Kochegarov AA, (2003) Pharmacological modulators of voltage-gated calcium channels and their therapeutical application. Cell Calcium 33: 145-162.
    • (2003) Cell Calcium , vol.33 , pp. 145-162
    • Kochegarov, A.A.1
  • 6
    • 75249106626 scopus 로고    scopus 로고
    • CNSB004 (Leconotide) causes antihyperalgesia without side effects when given intravenously: a comparison with ziconotide in a rat model of diabetic neuropathic pain
    • Kolosov A, Goodchild CS, Cooke I, (2010) CNSB004 (Leconotide) causes antihyperalgesia without side effects when given intravenously: a comparison with ziconotide in a rat model of diabetic neuropathic pain. Pain Med 11: 262-273.
    • (2010) Pain Med , vol.11 , pp. 262-273
    • Kolosov, A.1    Goodchild, C.S.2    Cooke, I.3
  • 7
    • 0027268233 scopus 로고
    • A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia
    • Valentino K, Newcomb R, Gadbois T, Singh T, Bowersox S, et al. (1993) A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia. Proc Natl Acad Sci U S A 90: 7894-7897.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 7894-7897
    • Valentino, K.1    Newcomb, R.2    Gadbois, T.3    Singh, T.4    Bowersox, S.5
  • 8
    • 78349309295 scopus 로고    scopus 로고
    • L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease
    • Anekonda TS, Quinn JF, Harris C, Frahler K, Wadsworth TL, et al. (2010) L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease. Neurobiol Dis 41: 62-70.
    • (2010) Neurobiol Dis , vol.41 , pp. 62-70
    • Anekonda, T.S.1    Quinn, J.F.2    Harris, C.3    Frahler, K.4    Wadsworth, T.L.5
  • 9
    • 16644370412 scopus 로고    scopus 로고
    • Human RAS superfamily proteins and related GTPases
    • Colicelli J, (2004) Human RAS superfamily proteins and related GTPases. Sci STKE 2004 RE13.
    • (2004) Sci STKE 2004
    • Colicelli, J.1
  • 10
    • 0035821585 scopus 로고    scopus 로고
    • Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/Gem
    • Beguin P, Nagashima K, Gonoi T, Shibasaki T, Takahashi K, et al. (2001) Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/Gem. Nature 411: 701-706.
    • (2001) Nature , vol.411 , pp. 701-706
    • Beguin, P.1    Nagashima, K.2    Gonoi, T.3    Shibasaki, T.4    Takahashi, K.5
  • 11
    • 27144558611 scopus 로고    scopus 로고
    • Expression of Rem2, an RGK family small GTPase, reduces N-type calcium current without affecting channel surface density
    • Chen H, Puhl HL, 3rd, Niu SL, Mitchell DC, Ikeda SR, (2005) Expression of Rem2, an RGK family small GTPase, reduces N-type calcium current without affecting channel surface density. J Neurosci 25: 9762-9772.
    • (2005) J Neurosci , vol.25 , pp. 9762-9772
    • Chen, H.1    Puhl 3rd, H.L.2    Niu, S.L.3    Mitchell, D.C.4    Ikeda, S.R.5
  • 12
    • 0345060805 scopus 로고    scopus 로고
    • Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases
    • Finlin BS, Crump SM, Satin J, Andres DA, (2003) Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases. Proc Natl Acad Sci U S A 100: 14469-14474.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 14469-14474
    • Finlin, B.S.1    Crump, S.M.2    Satin, J.3    Andres, D.A.4
  • 13
    • 76349089147 scopus 로고    scopus 로고
    • Rad as a novel regulator of excitation-contraction coupling and beta-adrenergic signaling in heart
    • Wang G, Zhu X, Xie W, Han P, Li K, et al. (2010) Rad as a novel regulator of excitation-contraction coupling and beta-adrenergic signaling in heart. Circ Res 106: 317-327.
    • (2010) Circ Res , vol.106 , pp. 317-327
    • Wang, G.1    Zhu, X.2    Xie, W.3    Han, P.4    Li, K.5
  • 14
    • 37349037208 scopus 로고    scopus 로고
    • Rad GTPase deficiency leads to cardiac hypertrophy
    • Chang L, Zhang J, Tseng YH, Xie CQ, Ilany J, et al. (2007) Rad GTPase deficiency leads to cardiac hypertrophy. Circulation 116: 2976-2983.
    • (2007) Circulation , vol.116 , pp. 2976-2983
    • Chang, L.1    Zhang, J.2    Tseng, Y.H.3    Xie, C.Q.4    Ilany, J.5
  • 15
    • 78650838735 scopus 로고    scopus 로고
    • Regulation of calcium channels by RGK proteins
    • Flynn R, Zamponi GW, (2010) Regulation of calcium channels by RGK proteins. Channels (Austin) 4: 434-439.
    • (2010) Channels (Austin) , vol.4 , pp. 434-439
    • Flynn, R.1    Zamponi, G.W.2
  • 16
    • 77954063290 scopus 로고    scopus 로고
    • Rem, a member of the RGK GTPases, inhibits recombinant CaV1.2 channels using multiple mechanisms that require distinct conformations of the GTPase
    • Yang T, Xu X, Kernan T, Wu V, Colecraft HM, (2010) Rem, a member of the RGK GTPases, inhibits recombinant CaV1.2 channels using multiple mechanisms that require distinct conformations of the GTPase. J Physiol 588: 1665-1681.
    • (2010) J Physiol , vol.588 , pp. 1665-1681
    • Yang, T.1    Xu, X.2    Kernan, T.3    Wu, V.4    Colecraft, H.M.5
  • 17
    • 69249113771 scopus 로고    scopus 로고
    • Engineering proteins for custom inhibition of Ca(V) channels
    • Xu X, Colecraft HM, (2009) Engineering proteins for custom inhibition of Ca(V) channels. Physiology (Bethesda) 24: 210-218.
    • (2009) Physiology (Bethesda) , vol.24 , pp. 210-218
    • Xu, X.1    Colecraft, H.M.2
  • 18
    • 77957124347 scopus 로고    scopus 로고
    • The {beta} Subunit of Voltage-Gated Ca2+ Channels
    • Buraei Z, Yang J, (2010) The {beta} Subunit of Voltage-Gated Ca2+ Channels. Physiol Rev 90: 1461-1506.
    • (2010) Physiol Rev , vol.90 , pp. 1461-1506
    • Buraei, Z.1    Yang, J.2
  • 19
    • 0345185172 scopus 로고    scopus 로고
    • Beta subunits of voltage-gated calcium channels
    • Dolphin AC, (2003) Beta subunits of voltage-gated calcium channels. J Bioenerg Biomembr 35: 599-620.
    • (2003) J Bioenerg Biomembr , vol.35 , pp. 599-620
    • Dolphin, A.C.1
  • 20
    • 36248968721 scopus 로고    scopus 로고
    • Genetically encoded molecules for inducibly inactivating CaV channels
    • Yang T, Suhail Y, Dalton S, Kernan T, Colecraft HM, (2007) Genetically encoded molecules for inducibly inactivating CaV channels. Nat Chem Biol 3: 795-804.
    • (2007) Nat Chem Biol , vol.3 , pp. 795-804
    • Yang, T.1    Suhail, Y.2    Dalton, S.3    Kernan, T.4    Colecraft, H.M.5
  • 21
    • 77957078802 scopus 로고    scopus 로고
    • Direct inhibition of P/Q-type voltage-gated Ca2+ channels by Gem does not require a direct Gem/Cavbeta interaction
    • Fan M, Buraei Z, Luo HR, Levenson-Palmer R, Yang J, (2010) Direct inhibition of P/Q-type voltage-gated Ca2+ channels by Gem does not require a direct Gem/Cavbeta interaction. Proc Natl Acad Sci U S A 107: 14887-14892.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14887-14892
    • Fan, M.1    Buraei, Z.2    Luo, H.R.3    Levenson-Palmer, R.4    Yang, J.5
  • 22
    • 33749323918 scopus 로고    scopus 로고
    • L-type calcium channel alpha-subunit and protein kinase inhibitors modulate Rem-mediated regulation of current
    • Crump SM, Correll RN, Schroder EA, Lester WC, Finlin BS, et al. (2006) L-type calcium channel alpha-subunit and protein kinase inhibitors modulate Rem-mediated regulation of current. Am J Physiol Heart Circ Physiol 291: H1959-1971.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Crump, S.M.1    Correll, R.N.2    Schroder, E.A.3    Lester, W.C.4    Finlin, B.S.5
  • 23
    • 34249666577 scopus 로고    scopus 로고
    • RGK small GTP-binding proteins interact with the nucleotide kinase domain of Ca2+-channel beta-subunits via an uncommon effector binding domain
    • Beguin P, Ng YJ, Krause C, Mahalakshmi RN, Ng MY, et al. (2007) RGK small GTP-binding proteins interact with the nucleotide kinase domain of Ca2+-channel beta-subunits via an uncommon effector binding domain. J Biol Chem 282: 11509-11520.
    • (2007) J Biol Chem , vol.282 , pp. 11509-11520
    • Beguin, P.1    Ng, Y.J.2    Krause, C.3    Mahalakshmi, R.N.4    Ng, M.Y.5
  • 24
    • 80052790674 scopus 로고    scopus 로고
    • Mechanism of auxiliary beta-subunit-mediated membrane targeting of L-type (Ca(V)1.2) channels
    • Fang K, Colecraft HM, (2011) Mechanism of auxiliary beta-subunit-mediated membrane targeting of L-type (Ca(V)1.2) channels. J Physiol 589: 4437-4455.
    • (2011) J Physiol , vol.589 , pp. 4437-4455
    • Fang, K.1    Colecraft, H.M.2
  • 25
    • 33845313646 scopus 로고    scopus 로고
    • PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane
    • Heo WD, Inoue T, Park WS, Kim ML, Park BO, et al. (2006) PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science 314: 1458-1461.
    • (2006) Science , vol.314 , pp. 1458-1461
    • Heo, W.D.1    Inoue, T.2    Park, W.S.3    Kim, M.L.4    Park, B.O.5
  • 26
    • 35348959358 scopus 로고    scopus 로고
    • Plasma membrane targeting is essential for Rem-mediated Ca2+ channel inhibition
    • Correll RN, Pang C, Finlin BS, Dailey AM, Satin J, et al. (2007) Plasma membrane targeting is essential for Rem-mediated Ca2+ channel inhibition. J Biol Chem 282: 28431-28440.
    • (2007) J Biol Chem , vol.282 , pp. 28431-28440
    • Correll, R.N.1    Pang, C.2    Finlin, B.S.3    Dailey, A.M.4    Satin, J.5
  • 27
    • 0035959942 scopus 로고    scopus 로고
    • Preassociation of calmodulin with voltage-gated Ca(2+) channels revealed by FRET in single living cells
    • Erickson MG, Alseikhan BA, Peterson BZ, Yue DT, (2001) Preassociation of calmodulin with voltage-gated Ca(2+) channels revealed by FRET in single living cells. Neuron 31: 973-985.
    • (2001) Neuron , vol.31 , pp. 973-985
    • Erickson, M.G.1    Alseikhan, B.A.2    Peterson, B.Z.3    Yue, D.T.4
  • 28
    • 0037629688 scopus 로고    scopus 로고
    • FRET two-hybrid mapping reveals function and location of L-type Ca2+ channel CaM preassociation
    • Erickson MG, Liang H, Mori MX, Yue DT, (2003) FRET two-hybrid mapping reveals function and location of L-type Ca2+ channel CaM preassociation. Neuron 39: 97-107.
    • (2003) Neuron , vol.39 , pp. 97-107
    • Erickson, M.G.1    Liang, H.2    Mori, M.X.3    Yue, D.T.4
  • 29
    • 77953900807 scopus 로고    scopus 로고
    • Rem GTPase interacts with the proximal Ca(V)1.2 C-terminus and modulates calcium-dependent channel inactivation
    • Pang C, Crump SM, Jin L, Correll RN, Finlin BS, et al. (2010) Rem GTPase interacts with the proximal Ca(V)1.2 C-terminus and modulates calcium-dependent channel inactivation. Channels (Austin) 4.
    • (2010) Channels (Austin) , vol.4
    • Pang, C.1    Crump, S.M.2    Jin, L.3    Correll, R.N.4    Finlin, B.S.5
  • 30
    • 37549054055 scopus 로고    scopus 로고
    • The RGK family of GTP-binding proteins: regulators of voltage-dependent calcium channels and cytoskeleton remodeling
    • Correll RN, Pang C, Niedowicz DM, Finlin BS, Andres DA, (2008) The RGK family of GTP-binding proteins: regulators of voltage-dependent calcium channels and cytoskeleton remodeling. Cell Signal 20: 292-300.
    • (2008) Cell Signal , vol.20 , pp. 292-300
    • Correll, R.N.1    Pang, C.2    Niedowicz, D.M.3    Finlin, B.S.4    Andres, D.A.5
  • 31
    • 28844455668 scopus 로고    scopus 로고
    • Nuclear sequestration of beta-subunits by Rad and Rem is controlled by 14-3-3 and calmodulin and reveals a novel mechanism for Ca2+ channel regulation
    • Beguin P, Mahalakshmi RN, Nagashima K, Cher DH, Ikeda H, et al. (2006) Nuclear sequestration of beta-subunits by Rad and Rem is controlled by 14-3-3 and calmodulin and reveals a novel mechanism for Ca2+ channel regulation. J Mol Biol 355: 34-46.
    • (2006) J Mol Biol , vol.355 , pp. 34-46
    • Beguin, P.1    Mahalakshmi, R.N.2    Nagashima, K.3    Cher, D.H.4    Ikeda, H.5
  • 32
    • 15744400089 scopus 로고    scopus 로고
    • Direct inhibition of the interaction between alpha-interaction domain and beta-interaction domain of voltage-dependent Ca2+ channels by Gem
    • Sasaki T, Shibasaki T, Beguin P, Nagashima K, Miyazaki M, et al. (2005) Direct inhibition of the interaction between alpha-interaction domain and beta-interaction domain of voltage-dependent Ca2+ channels by Gem. J Biol Chem 280: 9308-9312.
    • (2005) J Biol Chem , vol.280 , pp. 9308-9312
    • Sasaki, T.1    Shibasaki, T.2    Beguin, P.3    Nagashima, K.4    Miyazaki, M.5
  • 33
    • 25844453967 scopus 로고    scopus 로고
    • A single CaVbeta can reconstitute both trafficking and macroscopic conductance of voltage-dependent calcium channels
    • Dalton S, Takahashi SX, Miriyala J, Colecraft HM, (2005) A single CaVbeta can reconstitute both trafficking and macroscopic conductance of voltage-dependent calcium channels. J Physiol 567: 757-769.
    • (2005) J Physiol , vol.567 , pp. 757-769
    • Dalton, S.1    Takahashi, S.X.2    Miriyala, J.3    Colecraft, H.M.4
  • 34
    • 37649016193 scopus 로고    scopus 로고
    • Analysis of the Rem2 - voltage dependant calcium channel beta subunit interaction and Rem2 interaction with phosphorylated phosphatidylinositide lipids
    • Correll RN, Botzet GJ, Satin J, Andres DA, Finlin BS, (2008) Analysis of the Rem2 - voltage dependant calcium channel beta subunit interaction and Rem2 interaction with phosphorylated phosphatidylinositide lipids. Cell Signal 20: 400-408.
    • (2008) Cell Signal , vol.20 , pp. 400-408
    • Correll, R.N.1    Botzet, G.J.2    Satin, J.3    Andres, D.A.4    Finlin, B.S.5
  • 35
    • 23944515401 scopus 로고    scopus 로고
    • Regulation of L-type Ca2+ channel activity and insulin secretion by the Rem2 GTPase
    • Finlin BS, Mosley AL, Crump SM, Correll RN, Ozcan S, et al. (2005) Regulation of L-type Ca2+ channel activity and insulin secretion by the Rem2 GTPase. J Biol Chem 280: 41864-41871.
    • (2005) J Biol Chem , vol.280 , pp. 41864-41871
    • Finlin, B.S.1    Mosley, A.L.2    Crump, S.M.3    Correll, R.N.4    Ozcan, S.5
  • 36
    • 33750527124 scopus 로고    scopus 로고
    • Dose-dependent and isoform-specific modulation of Ca2+ channels by RGK GTPases
    • Seu L, Pitt GS, (2006) Dose-dependent and isoform-specific modulation of Ca2+ channels by RGK GTPases. J Gen Physiol 128: 605-613.
    • (2006) J Gen Physiol , vol.128 , pp. 605-613
    • Seu, L.1    Pitt, G.S.2
  • 37
    • 77957065470 scopus 로고    scopus 로고
    • Molecular mechanisms, and selective pharmacological rescue, of Rem-inhibited CaV1.2 channels in heart
    • Xu X, Marx SO, Colecraft HM, (2010) Molecular mechanisms, and selective pharmacological rescue, of Rem-inhibited CaV1.2 channels in heart. Circ Res 107: 620-630.
    • (2010) Circ Res , vol.107 , pp. 620-630
    • Xu, X.1    Marx, S.O.2    Colecraft, H.M.3
  • 38
    • 0032498538 scopus 로고    scopus 로고
    • Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells
    • Oancea E, Teruel MN, Quest AF, Meyer T, (1998) Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells. J Cell Biol 140: 485-498.
    • (1998) J Cell Biol , vol.140 , pp. 485-498
    • Oancea, E.1    Teruel, M.N.2    Quest, A.F.3    Meyer, T.4
  • 39
    • 10344223003 scopus 로고    scopus 로고
    • Imaging of receptor trafficking by using alpha-bungarotoxin-binding-site-tagged receptors
    • Sekine-Aizawa Y, Huganir RL, (2004) Imaging of receptor trafficking by using alpha-bungarotoxin-binding-site-tagged receptors. Proc Natl Acad Sci U S A 101: 17114-17119.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 17114-17119
    • Sekine-Aizawa, Y.1    Huganir, R.L.2
  • 40
    • 0038417528 scopus 로고    scopus 로고
    • Stimulation of protein kinase C inhibits bursting in disease-linked mutant human cardiac sodium channels
    • Tateyama M, Kurokawa J, Terrenoire C, Rivolta I, Kass RS, (2003) Stimulation of protein kinase C inhibits bursting in disease-linked mutant human cardiac sodium channels. Circulation 107: 3216-3222.
    • (2003) Circulation , vol.107 , pp. 3216-3222
    • Tateyama, M.1    Kurokawa, J.2    Terrenoire, C.3    Rivolta, I.4    Kass, R.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.