메뉴 건너뛰기




Volumn 67, Issue 21, 2010, Pages 3739-3748

Vector-based RNA interference of cathepsin B1 in Schistosoma mansoni

Author keywords

Cathepsin B; dsRNA hairpin; Functional genomics; Moloney murine leukaemia virus; Retrovirus; RNAi; Schistosomes; Transgenesis; Vector based RNAi; Viral transduction

Indexed keywords

CATHEPSIN B; DOUBLE STRANDED RNA; RETROVIRUS VECTOR;

EID: 78149469281     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0345-3     Document Type: Article
Times cited : (39)

References (53)
  • 2
    • 41849114954 scopus 로고    scopus 로고
    • Helminth infections: The great neglected tropical diseases
    • 1:CAS:528:DC%2BD1cXkt1Cntb4%3D 18382743
    • PJ Hotez PJ Brindley JM Bethony CH King EJ Pearce J Jacobson 2008 Helminth infections: the great neglected tropical diseases J Clin Invest 118 1311 1321 1:CAS:528:DC%2BD1cXkt1Cntb4%3D 18382743
    • (2008) J Clin Invest , vol.118 , pp. 1311-1321
    • Hotez, P.J.1    Brindley, P.J.2    Bethony, J.M.3    King, C.H.4    Pearce, E.J.5    Jacobson, J.6
  • 4
    • 34247280585 scopus 로고    scopus 로고
    • Manipulating the manipulators: Advances in parasitic helminth transgenesis and RNAi
    • 1:CAS:528:DC%2BD2sXkslKqs74%3D 17383233
    • BH Kalinna PJ Brindley 2007 Manipulating the manipulators: advances in parasitic helminth transgenesis and RNAi Trends Parasitol 23 197 204 1:CAS:528:DC%2BD2sXkslKqs74%3D 17383233
    • (2007) Trends Parasitol , vol.23 , pp. 197-204
    • Kalinna, B.H.1    Brindley, P.J.2
  • 6
    • 77749274193 scopus 로고    scopus 로고
    • Advances in mRNA silencing and transgene expression: A gateway to functional genomics in schistosomes
    • EB Tchoubrieva BH Kalinna 2009 Advances in mRNA silencing and transgene expression: a gateway to functional genomics in schistosomes Biotechnol Gen Eng Rev 26 273 292
    • (2009) Biotechnol Gen Eng Rev , vol.26 , pp. 273-292
    • Tchoubrieva, E.B.1    Kalinna, B.H.2
  • 8
    • 33846697738 scopus 로고    scopus 로고
    • Schistosomiasis mansoni: Novel chemotherapy using a cysteine protease inhibitor
    • 17214506
    • MH Abdulla KC Lim M Sajid JH McKerrow CR Caffrey 2007 Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor PLoS Med 4 e14 17214506
    • (2007) PLoS Med , vol.4 , pp. 14
    • Abdulla, M.H.1    Lim, K.C.2    Sajid, M.3    McKerrow, J.H.4    Caffrey, C.R.5
  • 9
    • 23944493302 scopus 로고    scopus 로고
    • Long-term suppression of cathepsin B levels by RNA interference retards schistosome growth
    • 1:CAS:528:DC%2BD2MXpsVCgsbY%3D 16076506
    • JM Correnti PJ Brindley EJ Pearce 2005 Long-term suppression of cathepsin B levels by RNA interference retards schistosome growth Mol Biochem Parasitol 143 209 215 1:CAS:528:DC%2BD2MXpsVCgsbY%3D 16076506
    • (2005) Mol Biochem Parasitol , vol.143 , pp. 209-215
    • Correnti, J.M.1    Brindley, P.J.2    Pearce, E.J.3
  • 10
    • 38049148695 scopus 로고    scopus 로고
    • RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade
    • 1:CAS:528:DC%2BD1cXot1yltQ%3D%3D 18067980
    • ME Morales G Rinaldi GN Gobert KJ Kines JF Tort PJ Brindley 2008 RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade Mol Biochem Parasitol 157 160 168 1:CAS:528:DC%2BD1cXot1yltQ%3D%3D 18067980
    • (2008) Mol Biochem Parasitol , vol.157 , pp. 160-168
    • Morales, M.E.1    Rinaldi, G.2    Gobert, G.N.3    Kines, K.J.4    Tort, J.F.5    Brindley, P.J.6
  • 11
    • 0030964211 scopus 로고    scopus 로고
    • Recognition of Schistosoma mansoni cathepsins B and L by human IgG1 and IgG4 antibodies
    • 1:CAS:528:DyaK2sXjvFagtLY%3D 9194098
    • J Grogan P Rotmans H Ghoneim A Deelder M Yazdanbakhsh MQ Klinkert 1997 Recognition of Schistosoma mansoni cathepsins B and L by human IgG1 and IgG4 antibodies Parasite Immunol 19 215 220 1:CAS:528:DyaK2sXjvFagtLY%3D 9194098
    • (1997) Parasite Immunol , vol.19 , pp. 215-220
    • Grogan, J.1    Rotmans, P.2    Ghoneim, H.3    Deelder, A.4    Yazdanbakhsh, M.5    Klinkert, M.Q.6
  • 12
    • 0023201292 scopus 로고
    • Sera of Schistosoma japonicum-infected patients cross-react with diagnostic 31/32 kD proteins of S. mansoni
    • 1:STN:280:DyaL1c%2FgtlSksg%3D%3D 3115655
    • A Ruppel YE Shi DX Wei HJ Diesfeld 1987 Sera of Schistosoma japonicum-infected patients cross-react with diagnostic 31/32 kD proteins of S. mansoni Clin Exp Immunol 69 291 298 1:STN:280:DyaL1c%2FgtlSksg%3D%3D 3115655
    • (1987) Clin Exp Immunol , vol.69 , pp. 291-298
    • Ruppel, A.1    Shi, Y.E.2    Wei, D.X.3    Diesfeld, H.J.4
  • 13
    • 0035851378 scopus 로고    scopus 로고
    • DNA vaccination with asparaginyl endopeptidase (Sm32) from the parasite Schistosoma mansoni: Anti-fecundity effect induced in mice
    • 1:CAS:528:DC%2BD3MXnslWntbg%3D 11672907
    • K Chlichlia M Bahgat A Ruppel V Schirrmacher 2001 DNA vaccination with asparaginyl endopeptidase (Sm32) from the parasite Schistosoma mansoni: anti-fecundity effect induced in mice Vaccine 20 439 447 1:CAS:528: DC%2BD3MXnslWntbg%3D 11672907
    • (2001) Vaccine , vol.20 , pp. 439-447
    • Chlichlia, K.1    Bahgat, M.2    Ruppel, A.3    Schirrmacher, V.4
  • 14
    • 0035087257 scopus 로고    scopus 로고
    • Vaccine efficacy of recombinant cathepsin D aspartic protease from Schistosoma japonicum
    • 1:CAS:528:DC%2BD3MXis1eku7c%3D 11240906
    • CK Verity DP McManus PJ Brindley 2001 Vaccine efficacy of recombinant cathepsin D aspartic protease from Schistosoma japonicum Parasite Immunol 23 153 162 1:CAS:528:DC%2BD3MXis1eku7c%3D 11240906
    • (2001) Parasite Immunol , vol.23 , pp. 153-162
    • Verity, C.K.1    McManus, D.P.2    Brindley, P.J.3
  • 15
    • 33845968082 scopus 로고    scopus 로고
    • A multienzyme network functions in intestinal protein digestion by a platyhelminth parasite
    • 1:CAS:528:DC%2BD28XhtlagsLnL 17028179
    • M Delcroix M Sajid CR Caffrey KC Lim J Dvorak I Hsieh M Bahgat C Dissous JH McKerrow 2006 A multienzyme network functions in intestinal protein digestion by a platyhelminth parasite J Biol Chem 281 39316 39329 1:CAS:528: DC%2BD28XhtlagsLnL 17028179
    • (2006) J Biol Chem , vol.281 , pp. 39316-39329
    • Delcroix, M.1    Sajid, M.2    Caffrey, C.R.3    Lim, K.C.4    Dvorak, J.5    Hsieh, I.6    Bahgat, M.7    Dissous, C.8    McKerrow, J.H.9
  • 18
    • 33644966336 scopus 로고    scopus 로고
    • Transduction of Schistosoma mansoni by vesicular stomatitis virus glycoprotein-pseudotyped Moloney murine leukemia retrovirus
    • 1:CAS:528:DC%2BD28Xis1Whs7s%3D 16530185
    • KJ Kines VH Mann ME Morales BD Shelby BH Kalinna GN Gobert SR Chirgwin PJ Brindley 2006 Transduction of Schistosoma mansoni by vesicular stomatitis virus glycoprotein-pseudotyped Moloney murine leukemia retrovirus Exp Parasitol 112 209 220 1:CAS:528:DC%2BD28Xis1Whs7s%3D 16530185
    • (2006) Exp Parasitol , vol.112 , pp. 209-220
    • Kines, K.J.1    Mann, V.H.2    Morales, M.E.3    Shelby, B.D.4    Kalinna, B.H.5    Gobert, G.N.6    Chirgwin, S.R.7    Brindley, P.J.8
  • 19
    • 48749124621 scopus 로고    scopus 로고
    • Integration of reporter trans-genes into Schistosoma mansoni chromosomes mediated by pseudotyped murine leukemia virus
    • 1:CAS:528:DC%2BD1cXpsVygtrs%3D 18403630
    • KJ Kines ME Morales VH Mann GN Gobert PJ Brindley 2008 Integration of reporter trans-genes into Schistosoma mansoni chromosomes mediated by pseudotyped murine leukemia virus Faseb J 22 2936 2948 1:CAS:528: DC%2BD1cXpsVygtrs%3D 18403630
    • (2008) Faseb J , vol.22 , pp. 2936-2948
    • Kines, K.J.1    Morales, M.E.2    Mann, V.H.3    Gobert, G.N.4    Brindley, P.J.5
  • 20
    • 1242338082 scopus 로고    scopus 로고
    • Schistosoma mansoni miracidia transformed by particle bombardment infect Biomphalaria glabrata snails and develop into transgenic sporocysts
    • 1:CAS:528:DC%2BD2cXht1Kisbg%3D 14969695
    • O Heyers AK Walduck PJ Brindley W Bleiss R Lucius T Dorbic B Wittig BH Kalinna 2003 Schistosoma mansoni miracidia transformed by particle bombardment infect Biomphalaria glabrata snails and develop into transgenic sporocysts Exp Parasitol 105 174 178 1:CAS:528:DC%2BD2cXht1Kisbg%3D 14969695
    • (2003) Exp Parasitol , vol.105 , pp. 174-178
    • Heyers, O.1    Walduck, A.K.2    Brindley, P.J.3    Bleiss, W.4    Lucius, R.5    Dorbic, T.6    Wittig, B.7    Kalinna, B.H.8
  • 21
    • 34247591062 scopus 로고    scopus 로고
    • Optimizing gene suppression in schistosomes using RNA interference
    • 1:CAS:528:DC%2BD2sXkslentbY%3D 17420062
    • G Krautz-Peterson M Radwanska D Ndegwa CB Shoemaker PJ Skelly 2007 Optimizing gene suppression in schistosomes using RNA interference Mol Biochem Parasitol 153 194 202 1:CAS:528:DC%2BD2sXkslentbY%3D 17420062
    • (2007) Mol Biochem Parasitol , vol.153 , pp. 194-202
    • Krautz-Peterson, G.1    Radwanska, M.2    Ndegwa, D.3    Shoemaker, C.B.4    Skelly, P.J.5
  • 22
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • 1:STN:280:DC%2BD38nis12jtw%3D%3D 11328886
    • MW Pfaffl 2001 A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 29 e45 1:STN:280:DC%2BD38nis12jtw%3D%3D 11328886
    • (2001) Nucleic Acids Res , vol.29 , pp. 45
    • Pfaffl, M.W.1
  • 23
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • 11972351
    • MW Pfaffl GW Horgan L Dempfle 2002 Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR Nucleic Acids Res 30 e36 11972351
    • (2002) Nucleic Acids Res , vol.30 , pp. 36
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 24
    • 0037386422 scopus 로고    scopus 로고
    • Suppression of cathepsin B expression in Schistosoma mansoni by RNA interference
    • 1:CAS:528:DC%2BD3sXivV2hsL4%3D 12705930
    • PJ Skelly A Da'dara DA Harn 2003 Suppression of cathepsin B expression in Schistosoma mansoni by RNA interference Int J Parasitol 33 363 369 1:CAS:528:DC%2BD3sXivV2hsL4%3D 12705930
    • (2003) Int J Parasitol , vol.33 , pp. 363-369
    • Skelly, P.J.1    Da'Dara, A.2    Harn, D.A.3
  • 25
    • 0031058227 scopus 로고    scopus 로고
    • The cysteine proteinases of Schistosoma mansoni cercariae
    • 9051919
    • JP Dalton KA Clough MK Jones PJ Brindley 1997 The cysteine proteinases of Schistosoma mansoni cercariae Parasitology 114 Pt 2 105 112 9051919
    • (1997) Parasitology , vol.114 , Issue.PART 2 , pp. 105-112
    • Dalton, J.P.1    Clough, K.A.2    Jones, M.K.3    Brindley, P.J.4
  • 26
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • EL Kaplan P Meier 1958 Nonparametric estimation from incomplete observations J Am Stat Assoc 53 457 481
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 27
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • 1:CAS:528:DC%2BD3cXit1agtrw%3D 10749213
    • SM Hammond E Bernstein D Beach GJ Hannon 2000 An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells Nature 404 293 296 1:CAS:528:DC%2BD3cXit1agtrw%3D 10749213
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 28
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • 1:CAS:528:DC%2BD3cXisVaitbo%3D 10778853
    • PD Zamore T Tuschl PA Sharp DP Bartel 2000 RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals Cell 101 25 33 1:CAS:528:DC%2BD3cXisVaitbo%3D 10778853
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 29
    • 1842766252 scopus 로고    scopus 로고
    • A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila
    • 1:CAS:528:DC%2BD2cXjtFWqtro%3D 15066284
    • JW Pham JL Pellino YS Lee RW Carthew EJ Sontheimer 2004 A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila Cell 117 83 94 1:CAS:528:DC%2BD2cXjtFWqtro%3D 15066284
    • (2004) Cell , vol.117 , pp. 83-94
    • Pham, J.W.1    Pellino, J.L.2    Lee, Y.S.3    Carthew, R.W.4    Sontheimer, E.J.5
  • 30
    • 0030970603 scopus 로고    scopus 로고
    • Cathepsin B-like activity predominates over cathepsin L-like activity in adult Schistosoma mansoni and S. japonicum
    • 1:STN:280:DyaK2szlsFehtg%3D%3D 9211519
    • CR Caffrey A Ruppel 1997 Cathepsin B-like activity predominates over cathepsin L-like activity in adult Schistosoma mansoni and S. japonicum Parasitol Res 83 632 635 1:STN:280:DyaK2szlsFehtg%3D%3D 9211519
    • (1997) Parasitol Res , vol.83 , pp. 632-635
    • Caffrey, C.R.1    Ruppel, A.2
  • 31
    • 0030071561 scopus 로고    scopus 로고
    • Cathepsin B of Schistosoma mansoni purification and activation of the recombinant proenzyme secreted by Saccharomyces cerevisiae
    • 1:CAS:528:DyaK28XlsVymug%3D%3D 8576174
    • G Lipps R Fullkrug E Beck 1996 Cathepsin B of Schistosoma mansoni purification and activation of the recombinant proenzyme secreted by Saccharomyces cerevisiae J Biol Chem 271 1717 1725 1:CAS:528: DyaK28XlsVymug%3D%3D 8576174
    • (1996) J Biol Chem , vol.271 , pp. 1717-1725
    • Lipps, G.1    Fullkrug, R.2    Beck, E.3
  • 32
    • 0030607410 scopus 로고    scopus 로고
    • Cysteine protease inhibitors block schistosome hemoglobin degradation in vitro and decrease worm burden and egg production in vivo
    • 1:CAS:528:DyaK28XlvVeisrw%3D 8898333
    • MM Wasilewski KC Lim J Phillips JH McKerrow 1996 Cysteine protease inhibitors block schistosome hemoglobin degradation in vitro and decrease worm burden and egg production in vivo Mol Biochem Parasitol 81 179 189 1:CAS:528:DyaK28XlvVeisrw%3D 8898333
    • (1996) Mol Biochem Parasitol , vol.81 , pp. 179-189
    • Wasilewski, M.M.1    Lim, K.C.2    Phillips, J.3    McKerrow, J.H.4
  • 33
    • 0032580348 scopus 로고    scopus 로고
    • Human gene therapy
    • 1:CAS:528:DyaK1cXjtVyltb0%3D 9579858
    • WF Anderson 1998 Human gene therapy Nature 392 25 30 1:CAS:528: DyaK1cXjtVyltb0%3D 9579858
    • (1998) Nature , vol.392 , pp. 25-30
    • Anderson, W.F.1
  • 34
    • 2342446492 scopus 로고    scopus 로고
    • Lentiviral and MLV based retroviral vectors for ex vivo and in vivo gene transfer
    • 1:CAS:528:DC%2BD2cXjs1CgsL0%3D 15121171
    • A Blesch 2004 Lentiviral and MLV based retroviral vectors for ex vivo and in vivo gene transfer Methods 33 164 172 1:CAS:528:DC%2BD2cXjs1CgsL0%3D 15121171
    • (2004) Methods , vol.33 , pp. 164-172
    • Blesch, A.1
  • 37
    • 0028124366 scopus 로고
    • Integration and germ-line transmission of a pseudotyped retroviral vector in zebrafish
    • 1:CAS:528:DyaK2cXlt1KgsbY%3D 8036514
    • S Lin N Gaiano P Culp JC Burns T Friedmann JK Yee N Hopkins 1994 Integration and germ-line transmission of a pseudotyped retroviral vector in zebrafish Science 265 666 669 1:CAS:528:DyaK2cXlt1KgsbY%3D 8036514
    • (1994) Science , vol.265 , pp. 666-669
    • Lin, S.1    Gaiano, N.2    Culp, P.3    Burns, J.C.4    Friedmann, T.5    Yee, J.K.6    Hopkins, N.7
  • 39
    • 0027228422 scopus 로고
    • Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
    • 1:CAS:528:DyaK3sXlslCqtbk%3D 8396259
    • JC Burns T Friedmann W Driever M Burrascano JK Yee 1993 Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells Proc Natl Acad Sci USA 90 8033 8037 1:CAS:528:DyaK3sXlslCqtbk%3D 8396259
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8033-8037
    • Burns, J.C.1    Friedmann, T.2    Driever, W.3    Burrascano, M.4    Yee, J.K.5
  • 40
    • 44249083931 scopus 로고    scopus 로고
    • Schistosoma japonicum: Inhibition of Mago nashi gene expression by shRNA-mediated RNA interference
    • 1:CAS:528:DC%2BD1cXmsFGksbo%3D 18466902
    • ZR Zhao L Lei M Liu SC Zhu CP Ren XN Wang JJ Shen 2008 Schistosoma japonicum: inhibition of Mago nashi gene expression by shRNA-mediated RNA interference Exp Parasitol 119 379 384 1:CAS:528:DC%2BD1cXmsFGksbo%3D 18466902
    • (2008) Exp Parasitol , vol.119 , pp. 379-384
    • Zhao, Z.R.1    Lei, L.2    Liu, M.3    Zhu, S.C.4    Ren, C.P.5    Wang, X.N.6    Shen, J.J.7
  • 41
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • 1:CAS:528:DC%2BD3MXlsVCqtrw%3D 11461699
    • A Grishok AE Pasquinelli D Conte N Li S Parrish I Ha DL Baillie A Fire G Ruvkun CC Mello 2001 Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing Cell 106 23 34 1:CAS:528:DC%2BD3MXlsVCqtrw%3D 11461699
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6    Baillie, D.L.7    Fire, A.8    Ruvkun, G.9    Mello, C.C.10
  • 42
    • 37449015629 scopus 로고    scopus 로고
    • Schistosoma mansoni: The dicer gene and its expression
    • 1:CAS:528:DC%2BD1cXhtlGguw%3D%3D 17707814
    • G Krautz-Peterson PJ Skelly 2008 Schistosoma mansoni: the dicer gene and its expression Exp Parasitol 118 122 128 1:CAS:528:DC%2BD1cXhtlGguw%3D%3D 17707814
    • (2008) Exp Parasitol , vol.118 , pp. 122-128
    • Krautz-Peterson, G.1    Skelly, P.J.2
  • 43
    • 0036358853 scopus 로고    scopus 로고
    • RNAi (Nematodes: Caenorhabditis elegans)
    • 1:CAS:528:DC%2BD38XktVSlsLc%3D 11931230
    • A Grishok CC Mello 2002 RNAi (Nematodes: Caenorhabditis elegans) Adv Genet 46 339 360 1:CAS:528:DC%2BD38XktVSlsLc%3D 11931230
    • (2002) Adv Genet , vol.46 , pp. 339-360
    • Grishok, A.1    Mello, C.C.2
  • 45
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • 1:CAS:528:DC%2BD3MXms12ksA%3D%3D 11201747
    • E Bernstein AA Caudy SM Hammond GJ Hannon 2001 Role for a bidentate ribonuclease in the initiation step of RNA interference Nature 409 363 366 1:CAS:528:DC%2BD3MXms12ksA%3D%3D 11201747
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 46
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in post-transcriptional gene silencing in plants
    • 1:CAS:528:DyaK1MXntFaktbY%3D 10542148
    • AJ Hamilton DC Baulcombe 1999 A species of small antisense RNA in post-transcriptional gene silencing in plants Science 286 950 952 1:CAS:528:DyaK1MXntFaktbY%3D 10542148
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.J.1    Baulcombe, D.C.2
  • 48
    • 51849124668 scopus 로고    scopus 로고
    • The long and short of inverted repeat genes in animals: MicroRNAs, mirtrons and hairpin RNAs
    • 1:CAS:528:DC%2BD1cXhtlajt7nN 18769156
    • K Okamura WJ Chung EC Lai 2008 The long and short of inverted repeat genes in animals: microRNAs, mirtrons and hairpin RNAs Cell Cycle 7 2840 2845 1:CAS:528:DC%2BD1cXhtlajt7nN 18769156
    • (2008) Cell Cycle , vol.7 , pp. 2840-2845
    • Okamura, K.1    Chung, W.J.2    Lai, E.C.3
  • 49
    • 30644463822 scopus 로고    scopus 로고
    • Design and cloning strategies for constructing shRNA expression vectors
    • 16396676
    • GJ McIntyre GC Fanning 2006 Design and cloning strategies for constructing shRNA expression vectors BMC Biotechnol 6 1 16396676
    • (2006) BMC Biotechnol , vol.6 , pp. 1
    • McIntyre, G.J.1    Fanning, G.C.2
  • 51
    • 1942519435 scopus 로고    scopus 로고
    • Blood 'n' guts: An update on schistosome digestive peptidases
    • 1:CAS:528:DC%2BD2cXjtl2nt78%3D 15105025
    • CR Caffrey JH McKerrow JP Salter M Sajid 2004 Blood 'n' guts: an update on schistosome digestive peptidases Trends Parasitol 20 241 248 1:CAS:528:DC%2BD2cXjtl2nt78%3D 15105025
    • (2004) Trends Parasitol , vol.20 , pp. 241-248
    • Caffrey, C.R.1    McKerrow, J.H.2    Salter, J.P.3    Sajid, M.4
  • 52
    • 0030918546 scopus 로고    scopus 로고
    • Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors
    • 1:CAS:528:DyaK2sXjtVOruro%3D 9165064
    • B Turk V Turk D Turk 1997 Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors Biol Chem 378 141 150 1:CAS:528:DyaK2sXjtVOruro%3D 9165064
    • (1997) Biol Chem , vol.378 , pp. 141-150
    • Turk, B.1    Turk, V.2    Turk, D.3
  • 53
    • 0002686989 scopus 로고
    • Studies of a proteolytic enzyme from Schistosoma mansoni
    • 1:CAS:528:DyaG1MXhtFahtrc%3D 13651581
    • AR Timms E Bueding 1959 Studies of a proteolytic enzyme from Schistosoma mansoni Br J Pharmacol Chemother 14 68 73 1:CAS:528:DyaG1MXhtFahtrc%3D 13651581
    • (1959) Br J Pharmacol Chemother , vol.14 , pp. 68-73
    • Timms, A.R.1    Bueding, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.