Curcumin reverses adriamycin-resistance of thermotolerant hepatocarcinoma cells by down-regulating P-glycoprotein and heat shock protein 70

Progress in Biochemistry and Biophysics

Volumn 39, Issue 2, 2012, Pages 151-160

  Qin, Chun Hong ^a   Li, Yong Guo ^b   Wu, Jiang ^a   He, Hong Jie ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Adriamycin resistance; Curcumin; Heat shock protein 70; P glycoprotein; Thermotolerance

Indexed keywords

EID: 84860871289     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2011.00288     Document Type: Article

References (41)

1. de Wit R, van der Zee J, van der Burg M E, et al. A phase I/II study of combined weekly systemic cisplatin and locoregional hyperthermia in patients with previously irradiated recurrent carcinoma of the uterine cervix. Br J Cancer, 1999, 80 (9): 1387-1391 (Pubitemid 29308607)
2. Harrison L E, Bryan M, Pliner L, et al. Phase I trial of pegylated liposomal doxorubicin with hyperthermic intraperitoneal chemotherapy in patients undergoing cytoreduction for advanced intra-abdominal malignancy. Ann Surg Oncol, 2008, 15 (5): 1407-1413
3. van der Zee J, Gonzalez Gonzalez D, van Rhoon G C, et al. Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial. Dutch Deep Hyperthermia Group. Lancet, 2000, 355 (9210): 1119-1125 (Pubitemid 30172932)
4. Sugarbaker P H. Laboratory and clinical basis for hyperthermia as a component of intracavitary chemotherapy. Int J Hyperthermia, 2007, 23 (5): 431-442 (Pubitemid 47272773)
5. Kamura T, Nielsen O S, Overgaard J, et al. Development of thermotolerance during fractionated hyperthermia in a solid tumor in vivo. Cancer Res, 1982, 42 (5): 1744-1748 (Pubitemid 12103368)
6. Rofstad E K, Brustad T. Development of thermotolerance in a human melanoma xenograft. Cancer Res, 1984, 44 (2): 525-530 (Pubitemid 14187448)
7. Griffin R J, Dings R P, Jamshidi-Parsian A, et al. Mild temperature hyperthermia and radiation therapy: role of tumour vascular thermotolerance and relevant physiological factors. Int J Hyperthermia, 2010, 26 (3): 256-263
8. Gerner E W, Schneider M J. Induced thermal resistance in HeLa cells. Nature, 1975, 256 (5517): 500-502
9. Meyer J L, Van Kersen I, Becker B, et al. The significance of thermotolerance after 41 degrees C hyperthermia: in vivo and in vitro tumor and normal tissue investigations. Int J Radiat Oncol Biol Phys, 1985, 11 (5): 973-981 (Pubitemid 15096663)
10. Rofstad E K, Midthjell H, Brustad T. Heat sensitivity and thermotolerance in cells from five human melanoma xenografts. Cancer Res, 1984, 44 (10): 4347-4354 (Pubitemid 14008748)
11. Sharma A, Meena A S, Bhat M K. Hyperthermia-associated carboplatin resistance: differential role of p53, HSF1 and Hsp70 in hepatoma cells. Cancer Sci, 2010, 101 (5): 1186-1193
12. Urano M, Kahn J, Kenton L A. Thermochemotherapy-induced resistance to cyclophosphamide. Br J Cancer, 1988, 57 (3): 295-297 (Pubitemid 18096340)
13. Hettinga J V, Lemstra W, Konings A W, et al. Cisplatin sensitivity and thermochemosensitisation in thermotolerant cDDP-sensitive and -resistant cell lines. Br J Cancer, 1995, 71 (3): 498-504
14. Hever-Szabo A, Pirity M, Szathmari M, et al. P-glycoprotein is overexpressed and functional in severely heat-shocked hepatoma cells. Anticancer Res, 1998, 18 (4C): 3045-3048 (Pubitemid 28388813)
15. Mishra B, Priyadarsini K I, Bhide M K, et al. Reactions of superoxide radicals with curcumin: probable mechanisms by optical spectroscopy and EPR. Free Radic Res, 2004, 38 (4): 355-362 (Pubitemid 38455859)
16. Ammon H P, Wahl MA. Pharmacology of Curcuma longa. Planta Med, 1991, 57 (1): 1-7
17. Nagabhushan M, Bhide S V. Nonmutagenicity of curcumin and its antimutagenic action versus chili and capsaicin. Nutr Cancer, 1986, 8 (3): 201-210 (Pubitemid 16077724)
18. Limtrakul P, Anuchapreeda S, Lipigorngoson S, et al. Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin. BMC Cancer, 2001, 1: 1
19. Asai A, Miyazawa T. Dietary curcuminoids prevent high-fat dietinduced lipid accumulation in rat liver and epididymal adipose tissue. J Nutr, 2001, 131 (11): 2932-2935 (Pubitemid 33063126)
20. Suryanarayana P, Krishnaswamy K, Reddy G B. Effect of curcumin on galactose-induced cataractogenesis in rats. Mol Vis, 2003, 9: 223-230 (Pubitemid 38097591)
21. Anuchapreeda S, Leechanachai P, SmithMM, et al. Modulation of P-glycoprotein expression and function by curcumin in multidrugresistant human KB cells. Biochem Pharmacol, 2002, 64 (4): 573-582
22. Tang X Q, Bi H, Feng J Q, et al. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR. Acta Pharmacol Sin, 2005, 26 (8): 1009-1016 (Pubitemid 41153224)
23. Harmsen S, Meijerman I, Febus C L, et al. PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line. Cancer Chemother Pharmacol, 2010, 66 (4): 765-771
24. Lee C A, Cook J A, Reyner E L, et al. P-glycoprotein related drug interactions: clinical importance and a consideration of disease states. Expert Opin Drug Metab Toxicol, 2010, 6 (5): 603-619
25. Li Y, Yuan H, Yang K, et al. The structure and functions of P-glycoprotein. Curr Med Chem, 2010, 17 (8): 786-800
26. Kerr I D, Jones P M, George A M. Multidrug efflux pumps: the structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues. FEBS J, 2010, 277 (3): 550-563
27. Goda K, Bacso Z, Szabo G. Multidrug resistance through the spectacle of P-glycoprotein. Curr Cancer Drug Targets, 2009, 9 (3): 281-297
28. Pajic M, Iyer J K, Kersbergen A, et al. Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer. Cancer Res, 2009, 69(16): 6396-6404
29. Sun L R, Zhong J L, Cui S X, et al. Modulation of P-glycoprotein activity by the substituted quinoxalinone compound QA3 in adriamycin-resistant K562/A02 cells. Pharmacol Rep, 2010, 62 (2): 333-342
30. Suttana W, Mankhetkorn S, Poompimon W, et al. Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols. Mol Cancer, 2010, 9: 99
31. Choi B H, Kim C G, Lim Y, et al. Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway. Cancer Lett, 2008, 259 (1): 111-118 (Pubitemid 350235095)
32. Limtrakul P, Chearwae W, Shukla S, et al. Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin. Mol Cell Biochem, 2007, 296 (1-2): 85-95
33. Miller B, Patel V A, Sorokin A. Cyclooxygenase-2 rescues rat mesangial cells from apoptosis induced by adriamycin via upregulation of multidrug resistance protein 1 (P-glycoprotein). J AmSoc Nephrol, 2006, 17 (4): 977-985
34. Calderwood S K, Asea A. Targeting HSP70-induced thermotolerance for design of thermal sensitizers. Int J Hyperthermia, 2002, 18 (6): 597-608 (Pubitemid 35469191)
35. Parcellier A, Gurbuxani S, Schmitt E, et al. Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways. Biochem Biophys Res Commun, 2003, 304 (3): 505-512 (Pubitemid 36506523)
36. Zheng Z, YenariMA. The application of HSP70 as a target for gene therapy. Front Biosci, 2006, 11: 699-707 (Pubitemid 43258173)
37. KimH P, Morse D, Choi AM. Heat-shock proteins: new keys to the development of cytoprotective therapies. Expert Opin Ther Targets, 2006, 10 (5): 759-769 (Pubitemid 44479983)
38. Khoei S, Goliaei B, Neshasteh-Riz A, et al. The role of heat shock protein 70 in the thermoresistance of prostate cancer cell line spheroids. FEBS Lett, 2004, 561 (1-3): 144-148 (Pubitemid 38317311)
39. Keenan J, Murphy L, Henry M, et al. Proteomic analysis of multidrug-resistance mechanisms in adriamycin-resistant variants of DLKP, a squamous lung cancer cell line. Proteomics, 2009, 9(6): 1556-1566
40. Smyth M J, Krasovskis E, Sutton V R, et al. The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis. Proc Natl Acad Sci USA, 1998, 95 (12): 7024-7029
41. Ribeil J A, Zermati Y, Vandekerckhove J, et al. Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1. Nature, 2007, 445 (7123): 102-105 (Pubitemid 46067309)