High glucose-induced Ca2 + overload and oxidative stress contribute to apoptosis of cardiac cells through mitochondrial dependent and independent pathways

Biochimica et Biophysica Acta - General Subjects

Volumn 1820, Issue 7, 2012, Pages 907-920

  Kumar, Sandeep ^a   Kain, Vasundhara ^a   Sitasawad, Sandhya L ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

Apoptosis; Calcium overload; H9c2 cells; High glucose; Mitochondrion; Reactive oxygen species

Indexed keywords

CALCIUM ION; CALPAIN 1; CASPASE 12; CASPASE 9; GLUCOSE; LIPOCORTIN 5; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM OVERLOAD; CALCIUM TRANSPORT; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL MEMBRANE; CELL POPULATION; CELL STRAIN; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA CONTENT; ENZYME ACTIVATION; FLOW CYTOMETRY; GLUCOSE METABOLISM; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; METABOLIC DISORDER; MITOCHONDRION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CALPAIN; CASPASES; CELL CYCLE; CELLS, CULTURED; CYTOCHROMES C; GLUCOSE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MYOCYTES, CARDIAC; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SWEETENING AGENTS;

RATTUS;

EID: 84860859535     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.02.010     Document Type: Article

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