Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region

Journal of Biological Chemistry

Volumn 287, Issue 20, 2012, Pages 16541-16549

  Ertekin, Asli ^a,b   Aramini, James M ^a   Rossi, Paolo ^a   Leonard, Paul G ^a,c,d   Janjua, Haleema ^a   Xiao, Rong ^a   Maglaqui, Melissa ^a   Lee, Hsiau Wei ^d   Prestegard, James H ^d   Montelione, Gaetano T ^a,c  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE HYDROGENS; C-TERMINAL REGIONS; CANCER CELLS; CELL CYCLE REGULATION; COMBINED METHOD; CYCLIN-DEPENDENT KINASE; DEUTERIUM EXCHANGE; DIMERIC STRUCTURE; DISULFIDE BOND FORMATION; N-TERMINALS; ORAL CANCER; SOLUTION STATE NMR; SOLUTION STRUCTURES; SPECIFIC INHIBITORS; TUMOR SUPPRESSOR PROTEINS;

AMIDES; CELLS; COVALENT BONDS; DEUTERIUM; ENZYMES; GENES; MASS SPECTROMETRY; PHOSPHORYLATION;

PROTEINS;

AMIDE; CYCLIN DEPENDENT KINASE 2 ASSOCIATED PROTEIN 1; CYSTEINE; DISULFIDE; HYDROGEN; I KAPPA B KINASE EPSILON; SERINE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DEUTERIUM HYDROGEN EXCHANGE; DISULFIDE BOND; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN PHOSPHORYLATION; STRUCTURE ANALYSIS;

ANIMALS; CELL LINE, TUMOR; CRICETINAE; CYCLIN-DEPENDENT KINASE 2; DISULFIDES; G1 PHASE; HUMANS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATION-REDUCTION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; S PHASE; TUMOR SUPPRESSOR PROTEINS;

CRICETINAE;

EID: 84860857091     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.343863     Document Type: Article

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