-
2
-
-
0008878205
-
Primary hepatic tumors of childhood
-
A. G. Weinberg, M. J. Finegold: Primary hepatic tumors of childhood. Hum Pathol 14, 512-37 (1983)
-
(1983)
Hum Pathol
, vol.14
, pp. 512-537
-
-
Weinberg, A.G.1
Finegold, M.J.2
-
3
-
-
0042572505
-
Where do we stand with hepatoblastoma? A review
-
J. M. Schnater, S. E. Kohler, W. H. Lamers, D. von Schweinitz, D. C. Aronson: Where do we stand with hepatoblastoma? A review. Cancer 98, 668-78 (2003)
-
(2003)
Cancer
, vol.98
, pp. 668-678
-
-
Schnater, J.M.1
Kohler, S.E.2
Lamers, W.H.3
Von Schweinitz, D.4
Aronson, D.C.5
-
4
-
-
22144477149
-
The emerging family of hepatoblastoma tumours: From ontogenesis to oncogenesis
-
A. Zimmermann: The emerging family of hepatoblastoma tumours: from ontogenesis to oncogenesis. Eur J Cancer 41, 1503-14 (2005)
-
(2005)
Eur J Cancer
, vol.41
, pp. 1503-1514
-
-
Zimmermann, A.1
-
5
-
-
0033556426
-
Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the b-catenin gene
-
A. Koch, D. Denkhaus, S. Albrecht, I. Leuschner, D. von Schweinitz, T. Pietsch: Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the b-catenin gene. Cancer Res 59, 269-273 (1999)
-
(1999)
Cancer Res
, vol.59
, pp. 269-273
-
-
Koch, A.1
Denkhaus, D.2
Albrecht, S.3
Leuschner, I.4
Von Schweinitz, D.5
Pietsch, T.6
-
6
-
-
0034719407
-
Activation of beta-catenin in epithelial and mesenchymal hepatoblastomas
-
Y. Wei, M. Fabre, S. Branchereau, F. Gauthier, G. Perilongo, M. A. Buendia: Activation of beta-catenin in epithelial and mesenchymal hepatoblastomas. Oncogene 19, 498-504 (2000)
-
(2000)
Oncogene
, vol.19
, pp. 498-504
-
-
Wei, Y.1
Fabre, M.2
Branchereau, S.3
Gauthier, F.4
Perilongo, G.5
Buendia, M.A.6
-
7
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
B. T. MacDonald, K. Tamai, X. He: Wnt/beta-Catenin Signaling: Components, Mechanisms, and Diseases Dev Cell 17, 9-26 (2009)
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
Macdonald, B.T.1
Tamai, K.2
He, X.3
-
8
-
-
57049182539
-
Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer
-
S. Cairo, C. Armengol, A. De Reynies, Y. Wei, E. Thomas, C. A. Renard, A. Goga, A. Balakrishnan, M. Semeraro, L. Gresh, M. Pontoglio, H. Strick-Marchand, F. Levillayer, Y. Nouet, D. Rickman, F. Gauthier, S. Branchereau, L. Brugieres, V. Laithier, R. Bouvier, F. Boman, G. Basso, J. F. Michiels, P. Hofman, F. Arbez-Gindre, H. Jouan, M. C. Rousselet-Chapeau, D. Berrebi, L. Marcellin, F. Plenat, D. Zachar, M. Joubert, J. Selves, D. Pasquier, P. Bioulac-Sage, M. Grotzer, M. Childs, M. Fabre, M. A. Buendia: Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer. Cancer Cell 14, 471-84 (2008)
-
(2008)
Cancer Cell
, vol.14
, pp. 471-484
-
-
Cairo, S.1
Armengol, C.2
De Reynies, A.3
Wei, Y.4
Thomas, E.5
Renard, C.A.6
Goga, A.7
Balakrishnan, A.8
Semeraro, M.9
Gresh, L.10
Pontoglio, M.11
Strick-Marchand, H.12
Levillayer, F.13
Nouet, Y.14
Rickman, D.15
Gauthier, F.16
Branchereau, S.17
Brugieres, L.18
Laithier, V.19
Bouvier, R.20
Boman, F.21
Basso, G.22
Michiels, J.F.23
Hofman, P.24
Arbez-Gindre, F.25
Jouan, H.26
Rousselet-Chapeau, M.C.27
Berrebi, D.28
Marcellin, L.29
Plenat, F.30
Zachar, D.31
Joubert, M.32
Selves, J.33
Pasquier, D.34
Bioulac-Sage, P.35
Grotzer, M.36
Childs, M.37
Fabre, M.38
Buendia, M.A.39
more..
-
9
-
-
67349252606
-
Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways
-
A. M. Adesina, D. Lopez-Terrada, K. K. Wong, P. Gunaratne, Y. Nguyen, J. Pulliam, J. Margolin, M. J. Finegold: Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways. Hum Pathol 40, 843-53 (2009)
-
(2009)
Hum Pathol
, vol.40
, pp. 843-853
-
-
Adesina, A.M.1
Lopez-Terrada, D.2
Wong, K.K.3
Gunaratne, P.4
Nguyen, Y.5
Pulliam, J.6
Margolin, J.7
Finegold, M.J.8
-
10
-
-
0031456158
-
Wnt signaling: A common theme in anaimal development
-
K. M. Cadigan, R. Nusse: Wnt signaling: a common theme in anaimal development. Genes Dev 11, 3286-3305 (1997)
-
(1997)
Genes Dev
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
11
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
H. Clevers: Wnt/beta-catenin signaling in development and disease. Cell 127, 469-80 (2006)
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
12
-
-
0030975671
-
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
-
V. Korinek, N. Barker, P. J. Morin, D. van Wichen, R. de Weger, K. W. Kinzler, B. Vogelstein, H. Clevers: Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science 275, 1784-7 (1997)
-
(1997)
Science
, vol.275
, pp. 1784-1817
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
13
-
-
0029664368
-
Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
-
B. Rubinfeld, I. Albert, E. Porfiri, C. Fiol, S. Munemitsu, P. Polakis: Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly. Science 272, 1023-1026 (1996)
-
(1996)
Science
, vol.272
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
14
-
-
0037220834
-
Beta-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and lineage specification
-
S. P. Monga, H. K. Monga, X. Tan, K. Mule, P. Pediaditakis, G. K. Michalopoulos: Beta-catenin antisense studies in embryonic liver cultures: role in proliferation, apoptosis, and lineage specification. Gastroenterology 124, 202-16 (2003)
-
(2003)
Gastroenterology
, vol.124
, pp. 202-216
-
-
Monga, S.P.1
Monga, H.K.2
Tan, X.3
Mule, K.4
Pediaditakis, P.5
Michalopoulos, G.K.6
-
15
-
-
33744495398
-
Apc Tumor Suppressor Gene Is the "zonation-keeper" of mouse liver
-
S. Benhamouche, T. Decaens, C. Godard, R. Chambrey, D. S. Rickman, C. Moinard, M. Vasseur-Cognet, C. J. Kuo, A. Kahn, C. Perret, S. Colnot: Apc tumor suppressor gene is the "zonation-keeper" of mouse liver. Dev Cell 10, 759-70 (2006)
-
(2006)
Dev Cell
, vol.10
, pp. 759-770
-
-
Benhamouche, S.1
Decaens, T.2
Godard, C.3
Chambrey, R.4
Rickman, D.S.5
Moinard, C.6
Vasseur-Cognet, M.7
Kuo, C.J.8
Kahn, A.9
Perret, C.10
Colnot, S.11
-
16
-
-
55249106920
-
Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology
-
C. Cavard, S. Colnot, V. Audard, S. Benhamouche, L. Finzi, C. Torre, G. Grimber, C. Godard, B. Terris, C. Perret: Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology. Future Oncol 4, 647-60 (2008)
-
(2008)
Future Oncol
, vol.4
, pp. 647-660
-
-
Cavard, C.1
Colnot, S.2
Audard, V.3
Benhamouche, S.4
Finzi, L.5
Torre, C.6
Grimber, G.7
Godard, C.8
Terris, B.9
Perret, C.10
-
18
-
-
33846193290
-
The many ways of Wnt in cancer
-
P. Polakis: The many ways of Wnt in cancer. Curr Opin Genet Dev, 17, 45-51 (2007)
-
(2007)
Curr Opin Genet Dev
, vol.17
, pp. 45-51
-
-
Polakis, P.1
-
19
-
-
0033867475
-
Genetics of hepatocellular carcinoma
-
M. A. Buendia: Genetics of Hepatocellular Carcinoma. Semin Cancer Biol 10, 185-200 (2000)
-
(2000)
Semin Cancer Biol
, vol.10
, pp. 185-200
-
-
Buendia, M.A.1
-
20
-
-
33645223878
-
Genotype-phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC
-
J. Zucman-Rossi, E. Jeannot, J. Tran Van Nhieu, J. Y. Scoazec, C. Guettier, S. Rebouissou, Y. Bacq, E. Leteurtre, V. Paradis, S. Michalak, D. Wendum, L. Chiche, M. Fabre, L. Mellottee, C. Laurent, C. Partensky, D. Castaing, E. S. Zafrani, P. Laurent-Puig, C. Balabaud, P. Bioulac-Sage: Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC. Hepatology 43, 515-24 (2006)
-
(2006)
Hepatology
, vol.43
, pp. 515-524
-
-
Zucman-Rossi, J.1
Jeannot, E.2
Tran Van Nhieu, J.3
Scoazec, J.Y.4
Guettier, C.5
Rebouissou, S.6
Bacq, Y.7
Leteurtre, E.8
Paradis, V.9
Michalak, S.10
Wendum, D.11
Chiche, L.12
Fabre, M.13
Mellottee, L.14
Laurent, C.15
Partensky, C.16
Castaing, D.17
Zafrani, E.S.18
Laurent-Puig, P.19
Balabaud, C.20
Bioulac-Sage, P.21
more..
-
21
-
-
0345006147
-
Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
-
A. de La Coste, B. Romagnolo, P. Billuart, C. A. Renard, M. A. Buendia, O. Soubrane, M. Fabre, J. Chelly, C. Beldjord, A. Kahn, C. Perret: Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci U S A 95, 8847-51 (1998)
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8847-8851
-
-
De La Coste, A.1
Romagnolo, B.2
Billuart, P.3
Renard, C.A.4
Buendia, M.A.5
Soubrane, O.6
Fabre, M.7
Chelly, J.8
Beldjord, C.9
Kahn, A.10
Perret, C.11
-
22
-
-
0034088858
-
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
-
S. Satoh, Y. Daigo, Y. Furukawa, T. Kato, N. Miwa, T. Nishiwaki, T. Kawasoe, H. Ishiguro, M. Fujita, T. Tokino, Y. Sasaki, S. Imaoka, M. Murata, T. Shimano, Y. Yamaoka, Y. Nakamura: AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat Genet 24, 245-250 (2000)
-
(2000)
Nat Genet
, vol.24
, pp. 245-250
-
-
Satoh, S.1
Daigo, Y.2
Furukawa, Y.3
Kato, T.4
Miwa, N.5
Nishiwaki, T.6
Kawasoe, T.7
Ishiguro, H.8
Fujita, M.9
Tokino, T.10
Sasaki, Y.11
Imaoka, S.12
Murata, M.13
Shimano, T.14
Yamaoka, Y.15
Nakamura, Y.16
-
23
-
-
0035870293
-
Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin
-
A. Cadoret, C. Ovejero, S. Saadi-Kheddouci, E. Souil, M. Fabre, B. Romagnolo, A. Kahn, C. Perret: Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin. Cancer Res 61, 3245-9. (2001)
-
(2001)
Cancer Res
, vol.61
, pp. 3245-3339
-
-
Cadoret, A.1
Ovejero, C.2
Saadi-Kheddouci, S.3
Souil, E.4
Fabre, M.5
Romagnolo, B.6
Kahn, A.7
Perret, C.8
-
24
-
-
10344254872
-
Livertargeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
-
S. Colnot, T. Decaens, M. Niwa-Kawakita, C. Godard, G. Hamard, A. Kahn, M. Giovannini, C. Perret: Livertargeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas. Proc Natl Acad Sci U S A 101, 17216-21 (2004)
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 17216-18121
-
-
Colnot, S.1
Decaens, T.2
Niwa-Kawakita, M.3
Godard, C.4
Hamard, G.5
Kahn, A.6
Giovannini, M.7
Perret, C.8
-
25
-
-
0345643474
-
Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma
-
H. Blaker, W. J. Hofmann, R. J. Rieker, R. Penzel, M. Graf, H. F. Otto: Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma. Genes Chromosomes Cancer 25, 399-402 (1999)
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 399-402
-
-
Blaker, H.1
Hofmann, W.J.2
Rieker, R.J.3
Penzel, R.4
Graf, M.5
Otto, H.F.6
-
26
-
-
0034724962
-
Somatic mutations of beta-catenin play a crucial role in the tumorigenesis of sporadic hepatoblastoma
-
Y. M. Jeng, M. Z. Wu, T. L. Mao, M. H. Chang, H. C. Hsu: Somatic mutations of beta-catenin play a crucial role in the tumorigenesis of sporadic hepatoblastoma. Cancer Lett 152, 45-51. (2000)
-
(2000)
Cancer Lett
, vol.152
, pp. 45-51
-
-
Jeng, Y.M.1
Wu, M.Z.2
Mao, T.L.3
Chang, M.H.4
Hsu, H.C.5
-
27
-
-
0034906471
-
Frequent deletions and mutations of the beta-catenin gene are associated with over-expression of cyclin D1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma
-
H. Takayasu, H. Horie, E. Hiyama, T. Matsunaga, Y. Hayashi, Y. Watanabe, S. Suita, M. Kaneko, F. Sasaki, K. Hashizume, T. Ozaki, K. Furuuchi, M. Tada, N. Ohnuma, A. Nakagawara: Frequent deletions and mutations of the beta-catenin gene are associated with overexpression of cyclin D1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma. Clin Cancer Res 7, 901-8 (2001)
-
(2001)
Clin Cancer Res
, vol.7
, pp. 901-908
-
-
Takayasu, H.1
Horie, H.2
Hiyama, E.3
Matsunaga, T.4
Hayashi, Y.5
Watanabe, Y.6
Suita, S.7
Kaneko, M.8
Sasaki, F.9
Hashizume, K.10
Ozaki, T.11
Furuuchi, K.12
Tada, M.13
Ohnuma, N.14
Nakagawara, A.15
-
28
-
-
0037130449
-
Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
-
K. Taniguchi, L. R. Roberts, I. N. Aderca, X. Dong, C. Qian, L. M. Murphy, D. M. Nagorney, L. J. Burgart, P. C. Roche, D. I. Smith, J. A. Ross, W. Liu: Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 21, 4863-71 (2002)
-
(2002)
Oncogene
, vol.21
, pp. 4863-4871
-
-
Taniguchi, K.1
Roberts, L.R.2
Aderca, I.N.3
Dong, X.4
Qian, C.5
Murphy, L.M.6
Nagorney, D.M.7
Burgart, L.J.8
Roche, P.C.9
Smith, D.I.10
Ross, J.A.11
Liu, W.12
-
29
-
-
9744277575
-
Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas
-
A. Koch, N. Weber, A. Waha, W. Hartmann, D. Denkhaus, J. Behrens, W. Birchmeier, D. von Schweinitz, T. Pietsch: Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas. J Pathol 204, 546-54 (2004)
-
(2004)
J Pathol
, vol.204
, pp. 546-554
-
-
Koch, A.1
Weber, N.2
Waha, A.3
Hartmann, W.4
Denkhaus, D.5
Behrens, J.6
Birchmeier, W.7
Von Schweinitz, D.8
Pietsch, T.9
-
30
-
-
0028800148
-
Biallelic inactivation of the APC gene in hepatoblastoma
-
H. Kurahashi, K. Takami, T. Oue, T. Kusafuka, A. Okada, A. Tawa, S. Okada, I. Nishisho: Biallelic inactivation of the APC gene in hepatoblastoma. Cancer Res 55, 5007-11 (1995)
-
(1995)
Cancer Res
, vol.55
, pp. 5007-5011
-
-
Kurahashi, H.1
Takami, K.2
Oue, T.3
Kusafuka, T.4
Okada, A.5
Tawa, A.6
Okada, S.7
Nishisho, I.8
-
31
-
-
33749188496
-
Should children at risk for familial adenomatous polyposis be screened for hepatoblastoma and children with apparently sporadic hepatoblastoma be screened for APC germline mutations?
-
S. Aretz, A. Koch, S. Uhlhaas, W. Friedl, P. Propping, D. von Schweinitz, T. Pietsch: Should children at risk for familial adenomatous polyposis be screened for hepatoblastoma and children with apparently sporadic hepatoblastoma be screened for APC germline mutations? Pediatr Blood Cancer 47, 811-818 (2006)
-
(2006)
Pediatr Blood Cancer
, vol.47
, pp. 811-818
-
-
Aretz, S.1
Koch, A.2
Uhlhaas, S.3
Friedl, W.4
Propping, P.5
Von Schweinitz, D.6
Pietsch, T.7
-
32
-
-
57749087003
-
B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver
-
K. R. Reed, D. Athineos, V. S. Meniel, J. A. Wilkins, R. A. Ridgway, Z. D. Burke, V. Muncan, A. R. Clarke, O. J. Sansom: B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver. Proc Natl Acad Sci U S A 105, 18919-23 (2008)
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 18919-19123
-
-
Reed, K.R.1
Athineos, D.2
Meniel, V.S.3
Wilkins, J.A.4
Ridgway, R.A.5
Burke, Z.D.6
Muncan, V.7
Clarke, A.R.8
Sansom, O.J.9
-
33
-
-
0031757172
-
Overexpression of cyclin D1 and cdk4 in tumorigenesis of sporadic hepatoblastomas
-
H. Kim, E. K. Ham, Y. I. Kim, J. G. Chi, H. S. Lee, S. H. Park, Y. M. Jung, N. K. Myung, M. J. Lee, J. J. Jang: Overexpression of cyclin D1 and cdk4 in tumorigenesis of sporadic hepatoblastomas. Cancer Lett 131, 177-83 (1998)
-
(1998)
Cancer Lett
, vol.131
, pp. 177-183
-
-
Kim, H.1
Ham, E.K.2
Kim, Y.I.3
Chi, J.G.4
Lee, H.S.5
Park, S.H.6
Jung, Y.M.7
Myung, N.K.8
Lee, M.J.9
Jang, J.J.10
-
34
-
-
33847073865
-
Tbx3 Is a Downstream Target of the Wnt/ß-Catenin Pathway and a Critical Mediator of ß-Catenin Survival Functions in Liver Cancer
-
C. A. Renard, C. Labalette, C. Armengol, D. Cougot, Y. Wei, S. Cairo, P. Pineau, C. Neuveut, A. de Reynies, A. Dejean, C. Perret, M. A. Buendia: Tbx3 Is a Downstream Target of the Wnt/ß-Catenin Pathway and a Critical Mediator of ß-Catenin Survival Functions in Liver Cancer. Cancer Res 67, 901-10 (2007)
-
(2007)
Cancer Res
, vol.67
, pp. 901-910
-
-
Renard, C.A.1
Labalette, C.2
Armengol, C.3
Cougot, D.4
Wei, Y.5
Cairo, S.6
Pineau, P.7
Neuveut, C.8
De Reynies, A.9
Dejean, A.10
Perret, C.11
Buendia, M.A.12
-
35
-
-
0037344296
-
Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms' tumors
-
O. Wirths, A. Waha, S. Weggen, P. Schirmacher, T. Kuhne, C. G. Goodyer, S. Albrecht, D. Von Schweinitz, T. Pietsch: Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms' tumors. Lab Invest 83, 429-34 (2003)
-
(2003)
Lab Invest
, vol.83
, pp. 429-434
-
-
Wirths, O.1
Waha, A.2
Weggen, S.3
Schirmacher, P.4
Kuhne, T.5
Goodyer, C.G.6
Albrecht, S.7
Von Schweinitz, D.8
Pietsch, T.9
-
36
-
-
33645227117
-
Zonal gene expression in murine liver: Lessons from tumors
-
S. Hailfinger, M. Jaworski, A. Braeuning, A. Buchmann, M. Schwarz: Zonal gene expression in murine liver: lessons from tumors. Hepatology 43, 407-14 (2006)
-
(2006)
Hepatology
, vol.43
, pp. 407-414
-
-
Hailfinger, S.1
Jaworski, M.2
Braeuning, A.3
Buchmann, A.4
Schwarz, M.5
-
37
-
-
33846463379
-
Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
-
S. Boyault, D. S. Rickman, A. de Reynies, C. Balabaud, S. Rebouissou, E. Jeannot, A. Herault, J. Saric, J. Belghiti, D. Franco, P. Bioulac-Sage, P. Laurent-Puig, J. Zucman-Rossi: Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology 45, 42-52 (2007)
-
(2007)
Hepatology
, vol.45
, pp. 42-52
-
-
Boyault, S.1
Rickman, D.S.2
De Reynies, A.3
Balabaud, C.4
Rebouissou, S.5
Jeannot, E.6
Herault, A.7
Saric, J.8
Belghiti, J.9
Franco, D.10
Bioulac-Sage, P.11
Laurent-Puig, P.12
Zucman-Rossi, J.13
-
38
-
-
41949105179
-
Rac1 activation controls nuclear localization of betacatenin during canonical Wnt signaling
-
X. Wu, X. Tu, K. S. Joeng, M. J. Hilton, D. A. Williams, F. Long: Rac1 activation controls nuclear localization of betacatenin during canonical Wnt signaling. Cell 133, 340-53 (2008)
-
(2008)
Cell
, vol.133
, pp. 340-353
-
-
Wu, X.1
Tu, X.2
Joeng, K.S.3
Hilton, M.J.4
Williams, D.A.5
Long, F.6
-
39
-
-
0042664109
-
Transcriptional profiling in hepatoblastomas using high-density oligonucleotide DNA array
-
T. Nagata, Y. Takahashi, Y. Ishii, S. Asai, Y. Nishida, A. Murata, T. Koshinaga, M. Fukuzawa, M. Hamazaki, K. Asami, E. Ito, H. Ikeda, H. Takamatsu, K. Koike, A. Kikuta, M. Kuroiwa, A. Watanabe, Y. Kosaka, H. Fujita, M. Miyake, H. Mugishima: Transcriptional profiling in hepatoblastomas using high-density oligonucleotide DNA array. Cancer Genet Cytogenet 145, 152-60 (2003)
-
(2003)
Cancer Genet Cytogenet
, vol.145
, pp. 152-160
-
-
Nagata, T.1
Takahashi, Y.2
Ishii, Y.3
Asai, S.4
Nishida, Y.5
Murata, A.6
Koshinaga, T.7
Fukuzawa, M.8
Hamazaki, M.9
Asami, K.10
Ito, E.11
Ikeda, H.12
Takamatsu, H.13
Koike, K.14
Kikuta, A.15
Kuroiwa, M.16
Watanabe, A.17
Kosaka, Y.18
Fujita, H.19
Miyake, M.20
Mugishima, H.21
more..
-
40
-
-
33750613935
-
Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas
-
J. H. Luo, B. Ren, S. Keryanov, G. C. Tseng, U. N. Rao, S. P. Monga, S. Strom, A. J. Demetris, M. Nalesnik, Y. P. Yu, S. Ranganathan, G. K. Michalopoulos: Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas. Hepatology 44, 1012-24 (2006)
-
(2006)
Hepatology
, vol.44
, pp. 1012-1024
-
-
Luo, J.H.1
Ren, B.2
Keryanov, S.3
Tseng, G.C.4
Rao, U.N.5
Monga, S.P.6
Strom, S.7
Demetris, A.J.8
Nalesnik, M.9
Yu, Y.P.10
Ranganathan, S.11
Michalopoulos, G.K.12
-
41
-
-
33748192942
-
The Myc oncoprotein as a therapeutic target for human cancer
-
M. Vita, M. Henriksson: The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 16, 318-30 (2006)
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 318-330
-
-
Vita, M.1
Henriksson, M.2
-
42
-
-
0037189025
-
Regulation of N-myc expression in development and disease
-
V. Strieder, W. Lutz: Regulation of N-myc expression in development and disease. Cancer Lett 180, 107-19 (2002)
-
(2002)
Cancer Lett
, vol.180
, pp. 107-119
-
-
Strieder, V.1
Lutz, W.2
-
43
-
-
33845334175
-
Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer
-
K. Pardali, A. Moustakas: Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer. Biochim Biophys Acta 1775, 21-62 (2007)
-
(2007)
Biochim Biophys Acta
, vol.1775
, pp. 21-62
-
-
Pardali, K.1
Moustakas, A.2
-
44
-
-
0037442685
-
Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor beta-induced repression of c-myc
-
T. Sasaki, H. Suzuki, K. Yagi, M. Furuhashi, R. Yao, S. Susa, T. Noda, Y. Arai, K. Miyazono, M. Kato: Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor beta-induced repression of c-myc. Cancer Res 63, 801-6 (2003)
-
(2003)
Cancer Res
, vol.63
, pp. 801-806
-
-
Sasaki, T.1
Suzuki, H.2
Yagi, K.3
Furuhashi, M.4
Yao, R.5
Susa, S.6
Noda, T.7
Arai, Y.8
Miyazono, K.9
Kato, M.10
-
45
-
-
0034682515
-
Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways
-
E. Labbe, A. Letamendia, L. Attisano: Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways. Proc Natl Acad Sci U S A 97, 8358-63 (2000)
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 8358-8363
-
-
Labbe, E.1
Letamendia, A.2
Attisano, L.3
-
46
-
-
0034677494
-
Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer
-
M. Nishita, M. K. Hashimoto, S. Ogata, M. N. Laurent, N. Ueno, H. Shibuya, K. W. Cho: Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer. Nature 403, 781-5 (2000)
-
(2000)
Nature
, vol.403
, pp. 781-785
-
-
Nishita, M.1
Hashimoto, M.K.2
Ogata, S.3
Laurent, M.N.4
Ueno, N.5
Shibuya, H.6
Cho, K.W.7
-
47
-
-
1642512639
-
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
-
M. Lepourcelet, Y. N. Chen, D. S. France, H. Wang, P. Crews, F. Petersen, C. Bruseo, A. W. Wood, R. A. Shivdasani: Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cell 5, 5-6 (2004)
-
(2004)
Cancer Cell
, vol.5
, pp. 5-6
-
-
Lepourcelet, M.1
Chen, Y.N.2
France, D.S.3
Wang, H.4
Crews, P.5
Petersen, F.6
Bruseo, C.7
Wood, A.W.8
Shivdasani, R.A.9
-
48
-
-
33646532114
-
The Wnt-dependent signaling pathways as target in oncology drug discovery
-
N. Janssens, M. Janicot, T. Perera: The Wnt-dependent signaling pathways as target in oncology drug discovery. Invest New Drugs 24, 263-80 (2006)
-
(2006)
Invest New Drugs
, vol.24
, pp. 263-280
-
-
Janssens, N.1
Janicot, M.2
Perera, T.3
-
49
-
-
70349695861
-
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
-
S. M. Huang, Y. M. Mishina, S. Liu, A. Cheung, F. Stegmeier, G. A. Michaud, O. Charlat, E. Wiellette, Y. Zhang, S. Wiessner, M. Hild, X. Shi, C. J. Wilson, C. Mickanin, V. Myer, A. Fazal, R. Tomlinson, F. Serluca, W. Shao, H. Cheng, M. Shultz, C. Rau, M. Schirle, J. Schlegl, S. Ghidelli, S. Fawell, C. Lu, D. Curtis, M. W. Kirschner, C. Lengauer, P. M. Finan, J. A. Tallarico, T. Bouwmeester, J. A. Porter, A. Bauer, F. Cong: Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461, 614-20 (2009)
-
(2009)
Nature
, vol.461
, pp. 614-620
-
-
Huang, S.M.1
Mishina, Y.M.2
Liu, S.3
Cheung, A.4
Stegmeier, F.5
Michaud, G.A.6
Charlat, O.7
Wiellette, E.8
Zhang, Y.9
Wiessner, S.10
Hild, M.11
Shi, X.12
Wilson, C.J.13
Mickanin, C.14
Myer, V.15
Fazal, A.16
Tomlinson, R.17
Serluca, F.18
Shao, W.19
Cheng, H.20
Shultz, M.21
Rau, C.22
Schirle, M.23
Schlegl, J.24
Ghidelli, S.25
Fawell, S.26
Lu, C.27
Curtis, D.28
Kirschner, M.W.29
Lengauer, C.30
Finan, P.M.31
Tallarico, J.A.32
Bouwmeester, T.33
Porter, J.A.34
Bauer, A.35
Cong, F.36
more..
-
50
-
-
67349198077
-
Activation of Wnt/beta-catenin signalling pathway induces chemoresistance to interferon-alpha/5-fluorouracil combination therapy for hepatocellular carcinoma
-
T. Noda, H. Nagano, I. Takemasa, S. Yoshioka, M. Murakami, H. Wada, S. Kobayashi, S. Marubashi, Y. Takeda, K. Dono, K. Umeshita, N. Matsuura, K. Matsubara, Y. Doki, M. Mori, M. Monden: Activation of Wnt/beta-catenin signalling pathway induces chemoresistance to interferon-alpha/5-fluorouracil combination therapy for hepatocellular carcinoma. Br J Cancer 100, 1647-58 (2009)
-
(2009)
Br J Cancer
, vol.100
, pp. 1647-1658
-
-
Noda, T.1
Nagano, H.2
Takemasa, I.3
Yoshioka, S.4
Murakami, M.5
Wada, H.6
Kobayashi, S.7
Marubashi, S.8
Takeda, Y.9
Dono, K.10
Umeshita, K.11
Matsuura, N.12
Matsubara, K.13
Doki, Y.14
Mori, M.15
Monden, M.16
-
51
-
-
67651003100
-
The emerging role of EpCAM in cancer and stem cell signaling
-
M. Munz, P. A. Baeuerle, O. Gires: The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res 69, 5627-9 (2009)
-
(2009)
Cancer Res
, vol.69
, pp. 5627-5659
-
-
Munz, M.1
Baeuerle, P.A.2
Gires, O.3
-
52
-
-
34547579096
-
Characterisation of the new EpCAM-specific antibody HO-3: Implications for trifunctional antibody immunotherapy of cancer
-
P. Ruf, O. Gires, M. Jäger, K. Fellinger, J. Atz, H. Lindhofer: Characterisation of the new EpCAM-specific antibody HO-3: implications for trifunctional antibody immunotherapy of cancer. Br J Cancer 97, 315-21 (2007)
-
(2007)
Br J Cancer
, vol.97
, pp. 315-321
-
-
Ruf, P.1
Gires, O.2
Jäger, M.3
Fellinger, K.4
Atz, J.5
Lindhofer, H.6
-
53
-
-
62549126478
-
Targeting Myc in pediatric malignancies of the central and peripheral nervous system
-
M. A. Grotzer, D. Castelletti, G. Fiaschetti, T. Shalaby, A. Arcaro: Targeting Myc in pediatric malignancies of the central and peripheral nervous system. Curr Cancer Drug Targets 9, 176-88 (2009)
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 176-188
-
-
Grotzer, M.A.1
Castelletti, D.2
Fiaschetti, G.3
Shalaby, T.4
Arcaro, A.5
-
54
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
J. Kota, R. R. Chivukula, K. A. O'Donnell, E. A. Wentzel, C. L. Montgomery, H. W. Hwang, T. C. Chang, P. Vivekanandan, M. Torbenson, K. R. Clark, J. R. Mendell, J. T. Mendell: Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137, 1005-17 (2009)
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'Donnell, K.A.3
Wentzel, E.A.4
Montgomery, C.L.5
Hwang, H.W.6
Chang, T.C.7
Vivekanandan, P.8
Torbenson, M.9
Clark, K.R.10
Mendell, J.R.11
Mendell, J.T.12
-
55
-
-
70350586771
-
Adaptive immunity in hepatocellular carcinoma: Prognostic and therapeutic implications
-
E. M. Fatourou, J. S. Koskinas: Adaptive immunity in hepatocellular carcinoma: prognostic and therapeutic implications Expert Rev Anticancer Ther, 9(10), 1499-510 (2009)
-
(2009)
Expert Rev Anticancer Ther
, vol.9
, Issue.10
, pp. 1499-1510
-
-
Fatourou, E.M.1
Koskinas, J.S.2
-
56
-
-
34347391261
-
CREB-a real culprit in oncogenesis
-
Y. T. Siu, D. Y. Jin: CREB-a real culprit in oncogenesis. FEBS J 274, 3224-32 (2007)
-
(2007)
FEBS J
, vol.274
, pp. 3224-3232
-
-
Siu, Y.T.1
Jin, D.Y.2
-
57
-
-
1242315877
-
HSP27 and HSP70: Potentially oncogenic apoptosis inhibitors
-
C. Garrido, E. Schmitt, C. Candé, N. Vahsen, A. Parcellier, G. Kroemer: HSP27 and HSP70: potentially oncogenic apoptosis inhibitors. Cell Cycle 2, 579-84 (2003)
-
(2003)
Cell Cycle
, vol.2
, pp. 579-584
-
-
Garrido, C.1
Schmitt, E.2
Candé, C.3
Vahsen, N.4
Parcellier, A.5
Kroemer, G.6
-
58
-
-
68549135304
-
Phospho-p70S6K and cdc2/cdk1 as therapeutic targets for diffuse large B-cell lymphoma
-
X. F. Zhao, R. B. Gartenhaus: Phospho-p70S6K and cdc2/cdk1 as therapeutic targets for diffuse large B-cell lymphoma. Expert Opin Ther Target 13, 1085-93 (2009)
-
(2009)
Expert Opin Ther Target
, vol.13
, pp. 1085-1093
-
-
Zhao, X.F.1
Gartenhaus, R.B.2
|