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Volumn 4 E, Issue 1, 2012, Pages 480-486

Activation of Wnt and Myc signaling in hepatoblastoma

Author keywords

Beta Catenin; Cancer; Genomics; Liver; Molecular Biology; Myc; Pediatric; Proteomics; Review

Indexed keywords

AXIN; BETA CATENIN; BONE MORPHOGENETIC PROTEIN 4; CYCLIN D1; CYTOKERATIN 1; EPITHELIAL CELL ADHESION MOLECULE; FRIZZLED PROTEIN; GLYCOGEN SYNTHASE KINASE 3; HEAT SHOCK PROTEIN 27; I KAPPA B ALPHA; MELANOMA ANTIGEN; MYC PROTEIN; S6 KINASE; STAT6 PROTEIN; T CELL FACTOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

EID: 84860853506     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: 10.2741/393     Document Type: Article
Times cited : (31)

References (58)
  • 1
    • 20344408300 scopus 로고    scopus 로고
    • Childhood solid tumours: A developmental disorder
    • P. J. Scotting, D. A. Walker, G. Perilongo: Childhood solid tumours: a developmental disorder. Nat Rev Cancer 5, 481-8 (2005)
    • (2005) Nat Rev Cancer , vol.5 , pp. 481-488
    • Scotting, P.J.1    Walker, D.A.2    Perilongo, G.3
  • 2
    • 0008878205 scopus 로고
    • Primary hepatic tumors of childhood
    • A. G. Weinberg, M. J. Finegold: Primary hepatic tumors of childhood. Hum Pathol 14, 512-37 (1983)
    • (1983) Hum Pathol , vol.14 , pp. 512-537
    • Weinberg, A.G.1    Finegold, M.J.2
  • 4
    • 22144477149 scopus 로고    scopus 로고
    • The emerging family of hepatoblastoma tumours: From ontogenesis to oncogenesis
    • A. Zimmermann: The emerging family of hepatoblastoma tumours: from ontogenesis to oncogenesis. Eur J Cancer 41, 1503-14 (2005)
    • (2005) Eur J Cancer , vol.41 , pp. 1503-1514
    • Zimmermann, A.1
  • 5
    • 0033556426 scopus 로고    scopus 로고
    • Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the b-catenin gene
    • A. Koch, D. Denkhaus, S. Albrecht, I. Leuschner, D. von Schweinitz, T. Pietsch: Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the b-catenin gene. Cancer Res 59, 269-273 (1999)
    • (1999) Cancer Res , vol.59 , pp. 269-273
    • Koch, A.1    Denkhaus, D.2    Albrecht, S.3    Leuschner, I.4    Von Schweinitz, D.5    Pietsch, T.6
  • 7
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • B. T. MacDonald, K. Tamai, X. He: Wnt/beta-Catenin Signaling: Components, Mechanisms, and Diseases Dev Cell 17, 9-26 (2009)
    • (2009) Dev Cell , vol.17 , pp. 9-26
    • Macdonald, B.T.1    Tamai, K.2    He, X.3
  • 9
    • 67349252606 scopus 로고    scopus 로고
    • Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways
    • A. M. Adesina, D. Lopez-Terrada, K. K. Wong, P. Gunaratne, Y. Nguyen, J. Pulliam, J. Margolin, M. J. Finegold: Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways. Hum Pathol 40, 843-53 (2009)
    • (2009) Hum Pathol , vol.40 , pp. 843-853
    • Adesina, A.M.1    Lopez-Terrada, D.2    Wong, K.K.3    Gunaratne, P.4    Nguyen, Y.5    Pulliam, J.6    Margolin, J.7    Finegold, M.J.8
  • 10
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in anaimal development
    • K. M. Cadigan, R. Nusse: Wnt signaling: a common theme in anaimal development. Genes Dev 11, 3286-3305 (1997)
    • (1997) Genes Dev , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 11
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • H. Clevers: Wnt/beta-catenin signaling in development and disease. Cell 127, 469-80 (2006)
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 13
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
    • B. Rubinfeld, I. Albert, E. Porfiri, C. Fiol, S. Munemitsu, P. Polakis: Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly. Science 272, 1023-1026 (1996)
    • (1996) Science , vol.272 , pp. 1023-1026
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3    Fiol, C.4    Munemitsu, S.5    Polakis, P.6
  • 14
    • 0037220834 scopus 로고    scopus 로고
    • Beta-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and lineage specification
    • S. P. Monga, H. K. Monga, X. Tan, K. Mule, P. Pediaditakis, G. K. Michalopoulos: Beta-catenin antisense studies in embryonic liver cultures: role in proliferation, apoptosis, and lineage specification. Gastroenterology 124, 202-16 (2003)
    • (2003) Gastroenterology , vol.124 , pp. 202-216
    • Monga, S.P.1    Monga, H.K.2    Tan, X.3    Mule, K.4    Pediaditakis, P.5    Michalopoulos, G.K.6
  • 17
    • 0038359353 scopus 로고    scopus 로고
    • Caught up in a Wnt storm: Wnt signaling in cancer
    • R. H. Giles, J. H. van Es, H. Clevers: Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta 1653, 1-24 (2003)
    • (2003) Biochim Biophys Acta , vol.1653 , pp. 1-24
    • Giles, R.H.1    Van Es, J.H.2    Clevers, H.3
  • 18
    • 33846193290 scopus 로고    scopus 로고
    • The many ways of Wnt in cancer
    • P. Polakis: The many ways of Wnt in cancer. Curr Opin Genet Dev, 17, 45-51 (2007)
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 45-51
    • Polakis, P.1
  • 19
    • 0033867475 scopus 로고    scopus 로고
    • Genetics of hepatocellular carcinoma
    • M. A. Buendia: Genetics of Hepatocellular Carcinoma. Semin Cancer Biol 10, 185-200 (2000)
    • (2000) Semin Cancer Biol , vol.10 , pp. 185-200
    • Buendia, M.A.1
  • 26
    • 0034724962 scopus 로고    scopus 로고
    • Somatic mutations of beta-catenin play a crucial role in the tumorigenesis of sporadic hepatoblastoma
    • Y. M. Jeng, M. Z. Wu, T. L. Mao, M. H. Chang, H. C. Hsu: Somatic mutations of beta-catenin play a crucial role in the tumorigenesis of sporadic hepatoblastoma. Cancer Lett 152, 45-51. (2000)
    • (2000) Cancer Lett , vol.152 , pp. 45-51
    • Jeng, Y.M.1    Wu, M.Z.2    Mao, T.L.3    Chang, M.H.4    Hsu, H.C.5
  • 31
    • 33749188496 scopus 로고    scopus 로고
    • Should children at risk for familial adenomatous polyposis be screened for hepatoblastoma and children with apparently sporadic hepatoblastoma be screened for APC germline mutations?
    • S. Aretz, A. Koch, S. Uhlhaas, W. Friedl, P. Propping, D. von Schweinitz, T. Pietsch: Should children at risk for familial adenomatous polyposis be screened for hepatoblastoma and children with apparently sporadic hepatoblastoma be screened for APC germline mutations? Pediatr Blood Cancer 47, 811-818 (2006)
    • (2006) Pediatr Blood Cancer , vol.47 , pp. 811-818
    • Aretz, S.1    Koch, A.2    Uhlhaas, S.3    Friedl, W.4    Propping, P.5    Von Schweinitz, D.6    Pietsch, T.7
  • 38
    • 41949105179 scopus 로고    scopus 로고
    • Rac1 activation controls nuclear localization of betacatenin during canonical Wnt signaling
    • X. Wu, X. Tu, K. S. Joeng, M. J. Hilton, D. A. Williams, F. Long: Rac1 activation controls nuclear localization of betacatenin during canonical Wnt signaling. Cell 133, 340-53 (2008)
    • (2008) Cell , vol.133 , pp. 340-353
    • Wu, X.1    Tu, X.2    Joeng, K.S.3    Hilton, M.J.4    Williams, D.A.5    Long, F.6
  • 41
    • 33748192942 scopus 로고    scopus 로고
    • The Myc oncoprotein as a therapeutic target for human cancer
    • M. Vita, M. Henriksson: The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 16, 318-30 (2006)
    • (2006) Semin Cancer Biol , vol.16 , pp. 318-330
    • Vita, M.1    Henriksson, M.2
  • 42
    • 0037189025 scopus 로고    scopus 로고
    • Regulation of N-myc expression in development and disease
    • V. Strieder, W. Lutz: Regulation of N-myc expression in development and disease. Cancer Lett 180, 107-19 (2002)
    • (2002) Cancer Lett , vol.180 , pp. 107-119
    • Strieder, V.1    Lutz, W.2
  • 43
    • 33845334175 scopus 로고    scopus 로고
    • Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer
    • K. Pardali, A. Moustakas: Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer. Biochim Biophys Acta 1775, 21-62 (2007)
    • (2007) Biochim Biophys Acta , vol.1775 , pp. 21-62
    • Pardali, K.1    Moustakas, A.2
  • 44
  • 45
    • 0034682515 scopus 로고    scopus 로고
    • Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways
    • E. Labbe, A. Letamendia, L. Attisano: Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways. Proc Natl Acad Sci U S A 97, 8358-63 (2000)
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8358-8363
    • Labbe, E.1    Letamendia, A.2    Attisano, L.3
  • 46
    • 0034677494 scopus 로고    scopus 로고
    • Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer
    • M. Nishita, M. K. Hashimoto, S. Ogata, M. N. Laurent, N. Ueno, H. Shibuya, K. W. Cho: Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer. Nature 403, 781-5 (2000)
    • (2000) Nature , vol.403 , pp. 781-785
    • Nishita, M.1    Hashimoto, M.K.2    Ogata, S.3    Laurent, M.N.4    Ueno, N.5    Shibuya, H.6    Cho, K.W.7
  • 48
    • 33646532114 scopus 로고    scopus 로고
    • The Wnt-dependent signaling pathways as target in oncology drug discovery
    • N. Janssens, M. Janicot, T. Perera: The Wnt-dependent signaling pathways as target in oncology drug discovery. Invest New Drugs 24, 263-80 (2006)
    • (2006) Invest New Drugs , vol.24 , pp. 263-280
    • Janssens, N.1    Janicot, M.2    Perera, T.3
  • 51
    • 67651003100 scopus 로고    scopus 로고
    • The emerging role of EpCAM in cancer and stem cell signaling
    • M. Munz, P. A. Baeuerle, O. Gires: The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res 69, 5627-9 (2009)
    • (2009) Cancer Res , vol.69 , pp. 5627-5659
    • Munz, M.1    Baeuerle, P.A.2    Gires, O.3
  • 52
    • 34547579096 scopus 로고    scopus 로고
    • Characterisation of the new EpCAM-specific antibody HO-3: Implications for trifunctional antibody immunotherapy of cancer
    • P. Ruf, O. Gires, M. Jäger, K. Fellinger, J. Atz, H. Lindhofer: Characterisation of the new EpCAM-specific antibody HO-3: implications for trifunctional antibody immunotherapy of cancer. Br J Cancer 97, 315-21 (2007)
    • (2007) Br J Cancer , vol.97 , pp. 315-321
    • Ruf, P.1    Gires, O.2    Jäger, M.3    Fellinger, K.4    Atz, J.5    Lindhofer, H.6
  • 55
    • 70350586771 scopus 로고    scopus 로고
    • Adaptive immunity in hepatocellular carcinoma: Prognostic and therapeutic implications
    • E. M. Fatourou, J. S. Koskinas: Adaptive immunity in hepatocellular carcinoma: prognostic and therapeutic implications Expert Rev Anticancer Ther, 9(10), 1499-510 (2009)
    • (2009) Expert Rev Anticancer Ther , vol.9 , Issue.10 , pp. 1499-1510
    • Fatourou, E.M.1    Koskinas, J.S.2
  • 56
    • 34347391261 scopus 로고    scopus 로고
    • CREB-a real culprit in oncogenesis
    • Y. T. Siu, D. Y. Jin: CREB-a real culprit in oncogenesis. FEBS J 274, 3224-32 (2007)
    • (2007) FEBS J , vol.274 , pp. 3224-3232
    • Siu, Y.T.1    Jin, D.Y.2
  • 58
    • 68549135304 scopus 로고    scopus 로고
    • Phospho-p70S6K and cdc2/cdk1 as therapeutic targets for diffuse large B-cell lymphoma
    • X. F. Zhao, R. B. Gartenhaus: Phospho-p70S6K and cdc2/cdk1 as therapeutic targets for diffuse large B-cell lymphoma. Expert Opin Ther Target 13, 1085-93 (2009)
    • (2009) Expert Opin Ther Target , vol.13 , pp. 1085-1093
    • Zhao, X.F.1    Gartenhaus, R.B.2


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