Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

Biochemical Journal

Volumn 441, Issue 3, 2012, Pages 927-936

  Hjerpe, Roland ^a   Thomas, Yann ^a   Chen, Jesse ^b   Zemla, Aleksandra ^a   Curran, Siobhan ^a   Shpiro, Natalia ^a   Dick, Lawrence R ^b   Kurz, Thimo ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Bortezomib; MG132; MLN4924; Neural precursor cell expressed developmentally down regulated 8 (NEDD8) activating enzyme (NAE); Proteasome; Ubiquitin activating enzyme

Indexed keywords

BORTEZOMIB; CULLIN; LYSINE; NEDD8 PROTEIN; PROTEASOME; UBIQUITIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONJUGATION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEINASE INHIBITION; UBIQUITINATION; YEAST;

ANIMALS; BORONIC ACIDS; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; ENZYME INHIBITORS; HEK293 CELLS; HELA CELLS; HUMANS; PYRAZINES; TRANSFECTION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; UBIQUITINS;

MAMMALIA;

EID: 84862908377     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111671     Document Type: Article

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