Small ubiquitin-like modifier (SUMO) modification of E1 Cys domain inhibits E1 Cys domain enzymatic activity

Journal of Biological Chemistry

Volumn 287, Issue 19, 2012, Pages 15154-15163

  Truong, Khue ^a   Lee, Terry D ^a   Chen, Yuan ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATION; ENVIRONMENTAL CHANGE; ENZYMATIC ACTIVITIES; HEAT-SHOCK; POST-TRANSLATIONAL MODIFICATIONS; SMALL UBIQUITIN-LIKE MODIFIERS; SUMO CONJUGATION; SUMOYLATION; TARGET PROTEINS; THIOESTERS; UBIQUITIN-LIKE;

BIOCHEMISTRY; BIOLOGY;

PROTEINS;

CYSTEINE; MEMBRANE PROTEIN; PROTEIN UBC9; SUMO ACTIVATING ENZYME E1; SUMO ACTIVATING ENZYME E2; SUMO E1 PROTEIN; SUMO E2 PROTEIN; SUMO PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CONJUGATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY; SUMOYLATION; TANDEM MASS SPECTROMETRY; UBIQUITINATION;

BINDING SITES; BLOTTING, WESTERN; CYSTEINE; HEK293 CELLS; HELA CELLS; HT29 CELLS; HUMANS; IMMUNOPRECIPITATION; MUTATION; PROTEIN BINDING; SUMO-1 PROTEIN; SUMOYLATION; TRANSFECTION; UBIQUITIN-ACTIVATING ENZYMES; UBIQUITIN-CONJUGATING ENZYMES;

EID: 84860852163     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.353789     Document Type: Article

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