Entropy-driven mechanism of an E3 ligase

Biochemistry

Volumn 50, Issue 25, 2011, Pages 5757-5766

  Truong, Khue ^a   Su, Yang ^a   Song, Jing ^a   Chen, Yuan ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENTHALPIES; ACTIVATION ENTROPIES; ALLOSTERIC EFFECT; BOUND WATER MOLECULES; CONFORMATIONAL FLEXIBILITY; CONFORMATIONAL SELECTION; CONFORMATIONAL STATE; E3 LIGASE; ENTROPIC EFFECTS; ENTROPY-DRIVEN MECHANISMS; ENZYMATIC MECHANISMS; EXPLICIT WATER; INTRINSICALLY UNSTRUCTURED PROTEINS; KINETIC ANALYSIS; LIGASES; MACROMOLECULAR CHEMISTRY; MOLECULAR DYNAMICS SIMULATIONS; PROTEIN-PROTEIN INTERACTIONS; SMALL UBIQUITIN-LIKE MODIFIERS; TEMPERATURE DEPENDENT; THIOESTERS; TRANSITION STATE; UBIQUITIN-LIKE;

ACTIVATION ANALYSIS; ACTIVATION ENERGY; BINDING ENERGY; CONFORMATIONS; DYNAMICS; ENTHALPY; ENZYMES; MACROMOLECULES; MOLECULAR DYNAMICS; PROTEINS; REACTION KINETICS;

ENTROPY;

NUCLEAR PROTEIN; PROTEIN RANBP2; SUMO PROTEIN; THIOESTER; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENTHALPY; ENTROPY; ENZYME KINETICS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIMULATION; TEMPERATURE DEPENDENCE;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ENTROPY; ENZYME ACTIVATION; ENZYME STABILITY; GENETIC VARIATION; GTPASE-ACTIVATING PROTEINS; HUMANS; KINETICS; MOLECULAR CHAPERONES; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; NUCLEAR PORE COMPLEX PROTEINS; PHASE TRANSITION; PROTEIN BINDING; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES;

EID: 79959432848     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2001856     Document Type: Article

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