Apoptosis and appearance of multinuclear C6 glioma cells after treatment by microtubule poisons

Acta Veterinaria

Volumn 62, Issue 1, 2012, Pages 17-26

  Mircic A ^a   Vilimanovic U ^a   Brajuskovic G ^a   Bumbasirevic V ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Apoptosis; Colchicine; Microtubules; Multinucleate cells; Paclitaxel

Indexed keywords

RATTUS;

EID: 84860830199     PISSN: 05678315     EISSN: 18207448     Source Type: Journal    
DOI: 10.2298/AVB1201017M     Document Type: Article

References (31)

1. Andersen SS, 2000, Spindle assembly and the artofregulating microtubule dynamicsby MAPs and Stathmin/Op 18, Trends cell Biol, 10, 261-7. (Pubitemid 30387030)
2. Biggiogera M, Bottone MG, Martin TE, Uchiomi T, Pellicciari C, 1997, Still immuno-detectable nuclear RNPs are extruded from the cytoplasm of spontanneously apoptotic thymocytes, Exp Cell Res, 234, 512-20. (Pubitemid 27335195)
3. Brito DA, Rieder CL, 2009, The Ability to Survive Mitosis in the Presence of Microtubule Poisons Differs Significantly Between Human Nontransformed (RPE-1) and Cancer (U2OS, HeLa) Cells, Cell Motil Cytoskeleton, 66, 437-47.
4. Bumbaširević V, Škaro-Milić A, Mirčić A, Djuričić B, 1995, Apoptosis induced by microtubule disrupting drugs in normal murine thymocytes in vitro, Scanning Microsc, 9, 509-18.
5. Bumbaširević V, Škaro-Milić A, Mirčić A, Duričić B, 1997, Apoptosis induced by microtubular poisons in thymocytes, In Lukic ML, Colic M, Mostarica-Stojkovic M, Cuperlovic K, editors, Immunoregulation in Health and Disease, London, Academic Press Ltd., 87-93.
6. Chaudhuri AR, Seetharamalu P, Schwarz PM, Hausheer FH, Luduena RF, 2000, The interaction of the B-ring of colchicine with alpha-tubulin: A novel footprinting approach. J Mol Biol, 303, 679-92.
7. Deveraux QL, Reed JC, 1999, IAP family proteins - Suppressors of apoptosis, Genes Dev, 13, 239-52. (Pubitemid 29095796)
8. El Hajouji A, Cunha M, Kirsch-Volders M, 1998, Spindle poison can induce polyploidy by mitotic slippage and micronucleate mononucleates in the cytokineses block assay, Mutagenesis, 13, 193-8. (Pubitemid 28138305)
9. Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, Stegh A et al., 2007, Malignant astrocytic glioma: genetics, biology, and paths to treatment, Genes Dev, 21, 2683-710. (Pubitemid 350070717)
10. Gajate C, Mollinedo F, 2005, Cytoskeleton-mediated death recepor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy, J Biol Chem, 280, 11641-7. (Pubitemid 40418478)
11. Galanis E, Buckner J, 2000, Chemotherapy for high-grade gliomas, Br J Cancer, 82, 1371-80. (Pubitemid 30175900)
12. Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L et al., 2007, Cell death modalities: classification and pathophysiological implications, Cell Death Differ, 14, 1237-43. (Pubitemid 46969863)
13. Giodini A, Kallio MJ, Wall NR, Gorbsky GJ, Tognin S, Marchisio PC et al., 2002, Regulation of microtubule stability and mitotic progression by surviving Cancer Res, 62, 2462-7. (Pubitemid 34462718)
14. Grobben B, De Deyn PP, Slegers H, 2002, Rat C6 glioma as experimental model system for the study of glioblastoma growth and invasion, Cell Tissue Res, 310, 257-70. (Pubitemid 35435769)
15. Harmon BV, Takano YS, Winterford CM, Potten CS, 1992, Cell death induced by vincristine in the intestinal crypts of mice and in a human Burkitt's lymphoma cell line, Cell Prolif, 25, 523-36.
16. Janardhanan R, Butler JT, Banik NL, Ray SK, 2009, N-(4-Hydroxyphenyl) retinamide potentiated paclitaxel for cell cycle arrest and apoptosis in glioblastoma C6 and RG2 cells, Brain Re, 2009, 1268, 142-53.
17. Jordan MA, Wilson L, 1998, Microtubules and actin filaments: Dynamic targets for cancer chemotherapy, Curr Opin Cell Biol, 10, 123-30. (Pubitemid 28066130)
18. Jordan MA, Wilson L, 2004, Microtubules as a target for anticancer drugs, Nature Rev Cancer, 4, 253-65. (Pubitemid 38525281)
19. Kerr JFR, Wyllie AH, Currie AR, 1972, Apoptosis: a basis biological phenomenon with wide-ranging implicatins in tissue kinetics, Br J Cancer, 26, 239-57.
20. Krajči D, Mareš V, Lisa V, Spanova A, Vorliček J, 2000, Ultrastructure of nuclei of cisplatin-treated C6 glioma cells undergoing apoptosis, Eur J Cell Biol, 79, 365-76. (Pubitemid 30345284)
21. Krakstad C, Chekenya M, 2010, Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics, Mol Cancer, 9, 135.
22. Landen JW, Hau V, Wang M, Davis T, Ciliax B, Wainer BH, et al., 2004, Noscapine crosses the bloodbrain barrier and inhibits glioblastoma growth, Clin Cancer Res, 10, 5187-201. (Pubitemid 39099794)
23. Lei K, Davis RJ, 2003, JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis, Proc Natl Acad Sci USA, 100, 2432-7. (Pubitemid 36297516)
24. Mandelkow E, Mandelkow EM, 1995, Microtubules and microtubule-associated proteins. Curr Opin Cell Biol, 7, 72-81.
25. Mirčić A, Brajušković G, Djurič ić B, Bumbaširević V, 2005, Comparison of cell death morphology of C6 glioma cells treated with topoisomerase inhibitors and microtubular poisons, XVIII Int Symp Morphol Sci, Abstract Book, 124.
26. Mollinedo F, Gajate C, 2003, Microtubules, microtubule-interfering agents and apoptosis, Apoptosis, 8, 411-50.
27. Okada H, Mak TW, 2004, Pathways of Apoptosis and Non Apoptotic Deathin Tumour Cells, Cancer, 4, 592-603. (Pubitemid 39025054)
28. Puthalakath H, Villunger A, O'Reilly LA, 2001, Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis, Science, 293, 1829-32. (Pubitemid 32845780)
29. Rao S, He L, Chakravarty S, 1999, Characterization of the Taxol binding site on the microtubule. Indentification of Atg (282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of Taxol, J Biol Chem, 274, 37990-4. (Pubitemid 30026868)
30. Walker NI, Harmon BV, Gobe GC, Kerr JFR, 1988, Patterns of cell death, Methods Achiev Exp Pathol, 13, 18-54.
31. Wang TH, Wang HS, Soong YK, 2000, Paclitaxel-induced cell death: Where the cell cycle and apoptosis come together, Cancer, 88, 2619-28.