A novel surface modified nitrendipine nanocrystals with enhancement of bioavailability and stability

International Journal of Pharmaceutics

Volumn 430, Issue 1-2, 2012, Pages 366-371

  Quan, Peng ^a   Shi, Kai ^a   Piao, Hongze ^a   Piao, Hongyu ^a   Liang, Na ^a   Xia, Dengning ^a   Cui, Fude ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Bioavailability; Chitosan; Dissolution; Nanocrystal; Nitrendipine

Indexed keywords

CHITOSAN; NANOCRYSTAL; NITRENDIPINE;

ANIMAL EXPERIMENT; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG STABILITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY DIFFRACTION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CALCIUM CHANNEL BLOCKERS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMICAL PRECIPITATION; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DELAYED-ACTION PREPARATIONS; DRUG STABILITY; MALE; NANOPARTICLES; NANOTECHNOLOGY; NITRENDIPINE; PARTICLE SIZE; RATS; RATS, WISTAR; SOLUBILITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 84860752950     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.04.025     Document Type: Article

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