Chitosan-Based Nanoparticles as a Hepatitis B Antigen Delivery System

Methods in Enzymology

Volumn 509, Issue , 2012, Pages 127-142

  Lebre, Filipa ^a,b   Bento, Dulce ^a,b   Jesus, Sandra ^a,b   Borges, Olga ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Adjuvants; Alginate; Chitosan; Delivery systems; Hepatitis B antigen; Nanoparticles; Particle characterization; Peyer's patches; Poly caprolactone; Spleen cells

Indexed keywords

ALGINIC ACID; CHITOSAN; HEPATITIS B ANTIGEN; NANOPARTICLE; POLYCAPROLACTONE;

ADSORPTION; ARTICLE; BIOLOGICAL ACTIVITY; CELL SUSPENSION; CELL VIABILITY; DRUG DELIVERY SYSTEM; HUMAN; IMMUNIZATION; IN VITRO STUDY; LYMPHOID ORGAN; MORPHOLOGY; MUCOSA; NONHUMAN; PARTICLE SIZE; PEYER PATCH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SPLEEN CELL; SURFACE PROPERTY; ZETA POTENTIAL;

ANIMALIA;

EID: 84860707034     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-391858-1.00007-1     Document Type: Chapter

References (29)

1. P. Baldrick The safety of chitosan as a pharmaceutical excipient Regul. Toxicol. Pharmacol. 56 2010 290 299
2. A. Berthold, K. Cremer, and J. Kreuter Preparation and characterization of chitosan microspheres as drug carrier for prednisolone sodium phosphate as model for anti-inflammatory drugs J. Control. Release 39 1996 17 25 (Pubitemid 26139808)
3. J. Bessa, and M.F. Bachmann T cell-dependent and -independent IgA responses: Role of TLR signalling Immunol. Invest. 39 2010 407 428
4. E. Bilensoy, C. Sarisozen, G. Esendagli, A.L. Dogan, Y. Aktas, M. Sen, and N.A. Mungan Intravesical cationic nanoparticles of chitosan and polycaprolactone for the delivery of Mitomycin C to bladder tumors Int. J. Pharm. 371 2009 170 176
5. O. Borges, G. Borchard, A. de Sousa, H.E. Junginger, and A. Cordeiro-da-Silva Induction of lymphocytes activated marker CD69 following exposure to chitosan and alginate biopolymers Int. J. Pharm. 337 2007 254 264 (Pubitemid 46756062)
6. O. Borges, G. Borchard, J.C. Verhoef, A. de Sousa, and H.E. Junginger Preparation of coated nanoparticles for a new mucosal vaccine delivery system Int. J. Pharm. 299 2005 155 166 (Pubitemid 40962417)
7. O. Borges, A. Cordeiro-da-Silva, S.G. Romeijn, M. Amidi, A. de Sousa, G. Borchard, and H.E. Junginger Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination J. Control. Release 114 2006 348 358 (Pubitemid 44310817)
8. O. Borges, J. Tavares, A. de Sousa, G. Borchard, H.E. Junginger, and A. Cordeiro-da-Silva Evaluation of the immune response following a short oral vaccination schedule with hepatitis B antigen encapsulated into alginate-coated chitosan nanoparticles Eur. J. Pharm. Sci. 32 2007 278 290 (Pubitemid 350051890)
9. S. De, and D. Robinson Polymer relationships during preparation of chitosan-alginate and poly-L-lysine-alginate nanospheres J. Control. Release 89 2003 101 112 (Pubitemid 36416617)
10. H. Fessi, J.P. Devissaguet, F. Puisieux, and C. Theis Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles 1992 United States Patent 5118528
11. S. Gallagher, and J. Smith One-dimensional gel electrophoresis of proteins Curr. Protoc. Immunol. 8.4 2003 1 21
12. M. Gonzalez Ferreiro, L. Tillman, G. Hardee, and R. Bodmeier Characterization of alginate/poly-L-lysine particles as antisense oligonucleotide carriers Int. J. Pharm. 239 2002 47 59 (Pubitemid 34615794)
13. N. Hussain, V. Jaitley, and A.T. Florence Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics Adv. Drug Deliv. Rev. 50 2001 107 142 (Pubitemid 32727279)
14. L. Illum Chitosan and its use as a pharmaceutical excipient Pharm. Res. 15 1998 1326 1331 (Pubitemid 28427917)
15. I. Jabbal-Gill Nasal vaccine innovation J. Drug Target. 18 2010 771 786
16. T. Jung, W. Kamm, A. Breitenbach, E. Kaiserling, J.X. Xiao, and T. Kissel Biodegradable nanoparticles for oral delivery of peptides: Is there a role for polymers to affect mucosal uptake? Eur. J. Pharm. Biopharm. 50 2000 147 160 (Pubitemid 30326694)
17. S.P. Kasturi, I. Skountzou, R.A. Albrecht, D. Koutsonanos, T. Hua, H.I. Nakaya, R. Ravindran, S. Stewart, M. Alam, M. Kwissa, F. Villinger, and N. Murthy Programming the magnitude and persistence of antibody responses with innate immunity Nature 470 2011 543 547
18. B. Kim, T. Bowersock, P. Griebel, A. Kidane, L.A. Babiuk, M. Sanchez, S. Attah-Poku, R.S. Kaushik, and G.K. Mutwiri Mucosal immune responses following oral immunization with rotavirus antigens encapsulated in alginate microspheres J. Control. Release 85 2002 191 202 (Pubitemid 35452637)
19. F. Lebre, G. Borchard, M.C. de Lima, and O. Borges Progress towards a needle-free hepatitis B vaccine Pharm. Res. 28 5 2011 986 1012
20. Malvern Zetasizer Nano Series 1992 User Manual. MAN 031,Issue 2.1
21. M.O. Oyewumi, A. Kumar, and Z. Cui Nano-microparticles as immune adjuvants: Correlating particle sizes and the resultant immune responses Expert Rev. Vaccines 9 2010 1095 1107
22. I. Panos, N. Acosta, and A. Heras New drug delivery systems based on chitosan Curr. Drug Discov. Technol. 5 2008 333 341
23. R. Pecora Dynamic light scattering measurement of nanometer particles in liquids J. Nanopart. Res. 2 2000 123 131 (Pubitemid 33230006)
24. M. Rajaonarivony, C. Vauthier, G. Couarraze, F. Puisieux, and P. Couvreur Development of a new drug carrier made from alginate J. Pharm. Sci. 82 1993 912 917 (Pubitemid 23317253)
25. K. Roy, H.Q. Mao, S.K. Huang, and K.W. Leong Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy Nat. Med. 5 1999 387 391 (Pubitemid 29180575)
26. Y. Thanavala, E. Lavelle, and P. Ogra All things mucosal Expert Rev. Vaccines 8 2009 139 142
27. I.M. Van Der Lubben, F.A. Konings, G. Borchard, J.C. Verhoef, and H.E. Junginger In vivo uptake of chitosan microparticles by murine Peyer's patches: Visualization studies using confocal laser scanning microscopy and immunohistochemistry J. Drug Target. 9 2001 39 47 (Pubitemid 32496449)
28. I.M. van der Lubben, J.C. Verhoef, G. Borchard, and H.E. Junginger Chitosan for mucosal vaccination Adv. Drug Deliv. Rev. 52 2001 139 144 (Pubitemid 33079169)
29. S. Wee, and W.R. Gombotz Protein release from alginate matrices Adv. Drug Deliv. Rev. 31 1998 267 285 (Pubitemid 28191869)