메뉴 건너뛰기




Volumn 118, Issue 2, 2012, Pages 47-57

Activation of aerobic metabolism by Amaranth oil improves heart rate variability both in athletes and patients with type 2 diabetes mellitus

Author keywords

Aerobic metabolism; Amaranth oil; Athletes; Correlations; Heart rate variability; Hormesis; Metabolic syndrome; Oxidative stress correction; Type 2 diabetes mellitus

Indexed keywords

REACTIVE OXYGEN METABOLITE; VEGETABLE OIL;

EID: 84860703211     PISSN: 13813455     EISSN: 17444160     Source Type: Journal    
DOI: 10.3109/13813455.2012.659259     Document Type: Article
Times cited : (24)

References (70)
  • 1
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P. (2002). Nonalcoholic fatty liver disease. N Engl J Med 346:1221-31.
    • (2002) N Engl J Med , vol.346 , pp. 1221-31
    • Angulo, P.1
  • 2
    • 0141924572 scopus 로고    scopus 로고
    • Heart rate variability in athletes
    • DOI 10.2165/00007256-200333120-00003
    • Aubert AE, Seps B, Beckers F. (2003). Heart rate variability in athletes. Sports Med 33:889-919. (Pubitemid 37255452)
    • (2003) Sports Medicine , vol.33 , Issue.12 , pp. 889-919
    • Aubert, A.E.1    Seps, B.2    Beckers, F.3
  • 6
    • 52249084516 scopus 로고    scopus 로고
    • Is heart rate a convenient tool to monitor overreaching? A systematic review of the literature
    • Bosquet L, Mekari S, Arvisais D, Aubert AE. (2008). Is heart rate a convenient tool to monitor overreaching? A systematic review of the literature. Br J Sports Med 42:709-14.
    • (2008) Br J Sports Med , vol.42 , pp. 709-14
    • Bosquet, L.1    Mekari, S.2    Arvisais, D.3    Aubert, A.E.4
  • 7
    • 77954672012 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of type 2 diabetes: From molecular mechanism to clinical implication
    • Chang Y-C, Chuang L-M. (2010). The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication. Am J Transl Res 2:316-31.
    • (2010) Am J Transl Res , vol.2 , pp. 316-31
    • Chang, Y.-C.1    Chuang, L.-M.2
  • 10
    • 0034845224 scopus 로고    scopus 로고
    • Heart rate variability and n-3 polyunsaturated fatty acids in patients with diabetes mellitus
    • DOI 10.1046/j.1365-2796.2001.00841.x
    • Christensen JH, Skou HA, Madsen T, Terring I, Schmidt EB. (2001). Heart rate variability and n-3 polyunsaturated fatty acids in patients with diabetes mellitus. J Int Med 249:545-52. (Pubitemid 32823863)
    • (2001) Journal of Internal Medicine , vol.249 , Issue.6 , pp. 545-552
    • Christensen, J.H.1    Skou, H.A.2    Madsen, T.3    Torring, I.4    Schmidt, E.B.5
  • 11
    • 65549169058 scopus 로고    scopus 로고
    • Conjugated linoleic acid isomers: Differences in metabolism and biological effects
    • Churruca I, Fernandez-Quintela A, Portillo MP. (2009). Conjugated linoleic acid isomers: Differences in metabolism and biological effects. Biofactors 35:105-11.
    • (2009) Biofactors , vol.35 , pp. 105-11
    • Churruca, I.1    Fernandez-Quintela, A.2    Portillo, M.P.3
  • 12
    • 37549061052 scopus 로고    scopus 로고
    • The roles of hyperglycaemia and oxidative stress in the rise and collapse of the natural protective mechanism against vascular endothelial cell dysfunction in diabetes
    • Cohen G, Riahi Y, Alpert E, Gruzman A, Sasson S. (2007). The roles of hyperglycaemia and oxidative stress in the rise and collapse of the natural protective mechanism against vascular endothelial cell dysfunction in diabetes. Arch Physiol Biochem 113:259-67.
    • (2007) Arch Physiol Biochem , vol.113 , pp. 259-67
    • Cohen, G.1    Riahi, Y.2    Alpert, E.3    Gruzman, A.4    Sasson, S.5
  • 13
    • 79959214007 scopus 로고    scopus 로고
    • Lipid peroxidation of polyunsaturated fatty acids in normal and obese adipose tissues
    • Cohen G, Riahi Y, Sasson S. (2011). Lipid peroxidation of polyunsaturated fatty acids in normal and obese adipose tissues. Arch Physiol Biochem 117:131-39.
    • (2011) Arch Physiol Biochem , vol.117 , pp. 131-39
    • Cohen, G.1    Riahi, Y.2    Sasson, S.3
  • 15
    • 0034491138 scopus 로고    scopus 로고
    • Beneficial effect(s) of n-3 fatty acids in cardiovascular diseases: But, why and how?
    • DOI 10.1054/plef.2000.0226
    • Das UN. (2000). Beneficial effect(s) of n-3 fatty acids in cardiovascular diseases: but, why and how? Prostagland Leukotrien Essent Fatty Acids 63:351-62. (Pubitemid 32096974)
    • (2000) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.63 , Issue.6 , pp. 351-362
    • Das, U.N.1
  • 16
    • 77954649706 scopus 로고    scopus 로고
    • Carotid body and cardiorespiratory alterations in intermittent hypoxia: The oxidative link
    • Del Rio R, Moya EA, Iturriaga R. (2010). Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link. Eur Respir J 36:143-50.
    • (2010) Eur Respir J , vol.36 , pp. 143-50
    • Del Rio, R.1    Moya, E.A.2    Iturriaga, R.3
  • 18
    • 54349088521 scopus 로고    scopus 로고
    • Novel aspects of adipocyteinduced skeletal muscle insulin resistance
    • Eckardt K, Sell H, Eckel J. (2008). Novel aspects of adipocyteinduced skeletal muscle insulin resistance. Arch Physiol Biochem 114:287-98.
    • (2008) Arch Physiol Biochem , vol.114 , pp. 287-98
    • Eckardt, K.1    Sell, H.2    Eckel, J.3
  • 19
    • 39149104320 scopus 로고    scopus 로고
    • The role for endoplasmic reticulum stress in diabetes mellitus
    • DOI 10.1210/er.2007-0015
    • Eizirik DL, Cardozo AK, Cnop M. (2008). The role for endoplasmic reticulum stress in diabetes mellitus. Endocr Rev 29:42-61. (Pubitemid 351252746)
    • (2008) Endocrine Reviews , vol.29 , Issue.1 , pp. 42-61
    • Eizirik, D.L.1    Cardozo, A.K.2    Cnop, M.3
  • 20
    • 34250864375 scopus 로고    scopus 로고
    • Reactive carbonyls and oxidative stress: Potential for therapeutic intervention
    • DOI 10.1016/j.pharmthera.2007.03.015, PII S0163725807000824
    • Ellis EM. (2007). Reactive carbonils and oxidative stress: potential for therapeutic intervention. Pharmacol Therapeutics 115:13-24. (Pubitemid 46990552)
    • (2007) Pharmacology and Therapeutics , vol.115 , Issue.1 , pp. 13-24
    • Ellis, E.M.1
  • 21
    • 62349116540 scopus 로고    scopus 로고
    • Insulin resistance, leptin and monocyte chemotactic protein-1 levels in diabetic and non-diabetic Afro-Caribbean subjects
    • Ezenwaka CE, Nwagbara E, Seales D, Okali F, Sell H, Eckel J. (2009). Insulin resistance, leptin and monocyte chemotactic protein-1 levels in diabetic and non-diabetic Afro-Caribbean subjects. Arch Physiol Biochem 115:22-7.
    • (2009) Arch Physiol Biochem , vol.115 , pp. 22-7
    • Ezenwaka, C.E.1    Nwagbara, E.2    Seales, D.3    Okali, F.4    Sell, H.5    Eckel, J.6
  • 22
    • 73449094974 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant defense mechanisms linked to exercise during cardiopulmonary and metabolic disorders
    • Fisher-Wellman K, Bell HK, Bloomer RJ. (2009). Oxidative stress and antioxidant defense mechanisms linked to exercise during cardiopulmonary and metabolic disorders. Oxid Med Cell Longevity 2:43-51.
    • (2009) Oxid Med Cell Longevity , vol.2 , pp. 43-51
    • Fisher-Wellman, K.1    Bell, H.K.2    Bloomer, R.J.3
  • 24
    • 33747596652 scopus 로고    scopus 로고
    • Oxygen sensing by mitochondria at complex III: The paradox of increased reactive oxygen species during hypoxia
    • DOI 10.1113/expphysiol.2006.033506
    • Guzy RD, Schumacker PT. (2006). Oxygen sensing by mitochondria at complex III: The paradox of increased ROS during hypoxia. Exp Physiol 91:807-19. (Pubitemid 44266577)
    • (2006) Experimental Physiology , vol.91 , Issue.5 , pp. 807-819
    • Guzy, R.D.1    Schumacker, P.T.2
  • 25
    • 56349146348 scopus 로고    scopus 로고
    • The relationship between heart rate variability and inflammatory markers in cardiovascular diseases
    • Haensel A, Mills PJ, Nelesen RA, Ziegler MG, Dimsdale JE. (2008). The relationship between heart rate variability and inflammatory markers in cardiovascular diseases. Psychoneuroendocrinol 33:1305-12.
    • (2008) Psychoneuroendocrinol , vol.33 , pp. 1305-12
    • Haensel, A.1    Mills, P.J.2    Nelesen, R.A.3    Ziegler, M.G.4    Dimsdale, J.E.5
  • 26
    • 80051669138 scopus 로고    scopus 로고
    • Oxidative stress and the etiology of insulin resistance and type 2 diabetes
    • Henriksen EJ, Diamond-Stanic MK, Marchionne EM. (2011). Oxidative stress and the etiology of insulin resistance and type 2 diabetes. Free Rad Biol Med 51:993-99.
    • (2011) Free Rad Biol Med , vol.51 , pp. 993-99
    • Henriksen, E.J.1    Diamond-Stanic, M.K.2    Marchionne, E.M.3
  • 27
    • 0030898205 scopus 로고    scopus 로고
    • Effects of physical training on heart rate variability in diabetic patients with various degrees of cardiovascular autonomic neuropathy
    • DOI 10.1016/S0008-6363(97)00040-0, PII S0008636397000400
    • Howorka K, Pumprla J, Haber P, Koller-Strametz J, Mondrzyk J, Schabmann A. (1997). Effects of physical training on heart rate variability in diabetic patients with various degrees of cardiovascular autonomic neuropathy. Cardiovasc Res 34: 206-14. (Pubitemid 27261931)
    • (1997) Cardiovascular Research , vol.34 , Issue.1 , pp. 206-214
    • Howorka, K.1    Pumprla, J.2    Haber, P.3    Koller-Strametz, J.4    Mondrzyk, J.5    Schabmann, A.6
  • 28
    • 0037062698 scopus 로고    scopus 로고
    • Conversion from vagal to sympathetic predominance with strenuous training in high-performance world class athletes
    • DOI 10.1161/01.CIR.0000018124.01299.AE
    • Iellamo F, Legramante JM, Pigozzi F, Spataro A, Norbiato G, Lucini D, Pagani M. (2002). Conversion from vagal to sympathetic predominance with strenuous training in high-performance world class athlete. Circulation 105:2719-24. (Pubitemid 34615141)
    • (2002) Circulation , vol.105 , Issue.23 , pp. 2719-2724
    • Iellamo, F.1    Legramante, J.M.2    Pigozzi, F.3    Spataro, A.4    Norbiato, G.5    Lucini, D.6    Pagani, M.7
  • 29
    • 33749993246 scopus 로고    scopus 로고
    • Disruption of mitochondrial redox circuitry in oxidative stress
    • DOI 10.1016/j.cbi.2006.07.008, PII S0009279706001906
    • Jones DP. (2006). Disruption of mitochondrial redox circuitry in oxidative stress. Chem Biol Interact 163:38-53. (Pubitemid 44572221)
    • (2006) Chemico-Biological Interactions , vol.163 , Issue.1-2 , pp. 38-53
    • Jones, D.P.1
  • 32
    • 0038367268 scopus 로고    scopus 로고
    • Reference on clinical biochemical laboratory diagnostics (in 2 volumes)
    • V.2, 494 pp
    • Kamyshnikov VS (Ed.). (2000). Reference on clinical biochemical laboratory diagnostics (in 2 volumes). Minsk: Belarus. V.1 495 pp.; V.2 494 pp.
    • (2000) Minsk: Belarus. , vol.1 , pp. 495
    • Kamyshnikov, V.S.1
  • 35
    • 0025234321 scopus 로고
    • A simple, sensitive assay for determination of superoxide dismutase activity based on reaction of quercetin oxidation
    • Kostyuk V, Potapovich A, Kovaleva Z. (1990). A simple sensitive assay for determination of superoxide dismutase activity based on reaction of quercetin oxidation. Vopr Med Khimii (in Russian) 2:88-91. (Pubitemid 20094361)
    • (1990) Voprosy Meditsinskoi Khimii , vol.36 , Issue.2 , pp. 88-91
    • Kostyuk, V.A.1    Potapovich, A.I.2    Kovaleva Zh., V.3
  • 37
    • 42949111471 scopus 로고    scopus 로고
    • Assessment of autonomic function in cardiovascular disease: Physiological basis and prognostic implications
    • DOI 10.1016/j.jacc.2008.01.038, PII S0735109708006955
    • Lahiri MK, Kannankeril PJ, Goldberger JJ. (2008). Assessment of autonomic function in cardiovascular disease: physiological basis and prognostic implications. J Am Coll Cardiol 51:1725-33. (Pubitemid 351608496)
    • (2008) Journal of the American College of Cardiology , vol.51 , Issue.18 , pp. 1725-1733
    • Lahiri, M.K.1    Kannankeril, P.J.2    Goldberger, J.J.3
  • 39
    • 50349096521 scopus 로고    scopus 로고
    • Genesis and regulation of the heart automaticity
    • Mangoni ME, Nargeot J. (2008). Genesis and regulation of the heart automaticity. Physiol Rev 88:919-82.
    • (2008) Physiol Rev , vol.88 , pp. 919-82
    • Mangoni, M.E.1    Nargeot, J.2
  • 41
    • 37049019484 scopus 로고    scopus 로고
    • Time-frequency analysis of heart rate variability during immediate recovery from low and high intensity exercise
    • DOI 10.1007/s00421-007-0594-5
    • Martinmi K, Rusko H.(2008). Time-frequency analysis of heart rate variability during immediate recovery from low and high intensity exercise. Eur J Appl Physiol. 102,353-60. (Pubitemid 350245960)
    • (2008) European Journal of Applied Physiology , vol.102 , Issue.3 , pp. 353-360
    • Martinmaki, K.1    Rusko, H.2
  • 43
    • 37749037128 scopus 로고    scopus 로고
    • Dietary factors, hormesis and health
    • Mattson MP. (2008). Dietary factors, hormesis and health. Ageing Res Rev 7:43-8.
    • (2008) Ageing Res Rev , vol.7 , pp. 43-8
    • Mattson, M.P.1
  • 46
    • 34548313690 scopus 로고    scopus 로고
    • Oxidants and antioxidants revisited. New concepts of oxidative stress
    • DOI 10.1080/10715760701490975, PII 781560819
    • Packer L, Cadenas E. (2007). Oxidants and antioxidants revisited. New concepts of oxidative stress. Free Radical Res 41:951-52. (Pubitemid 47343397)
    • (2007) Free Radical Research , vol.41 , Issue.9 , pp. 951-952
    • Packer, L.1    Cadenas, E.2
  • 47
    • 67149092183 scopus 로고    scopus 로고
    • Molecules, water, and radiant energy: New clues for the origin of life
    • Pollack GH, Figueroa X, Zhao Q. (2009). Molecules, water, and radiant energy: New clues for the origin of life. Int J Mol Sci 10:1419-29.
    • (2009) Int J Mol Sci , vol.10 , pp. 1419-29
    • Pollack, G.H.1    Figueroa, X.2    Zhao, Q.3
  • 48
    • 37849004479 scopus 로고    scopus 로고
    • Systemic adaptation to oxidative challenge induced by regular exercise
    • Radak Z, Chung HY, Goto S. (2008). Systemic adaptation to oxidative challenge induced by regular exercise. Free Rad Biol Med 44:153-59.
    • (2008) Free Rad Biol Med , vol.44 , pp. 153-59
    • Radak, Z.1    Chung, H.Y.2    Goto, S.3
  • 49
    • 79551470306 scopus 로고    scopus 로고
    • Oxidative stress, insulin signaling, and diabetes
    • Rains JL, Jain SK. (2011). Oxidative stress, insulin signaling, and diabetes. Free Rad Biol Med 50:567-75.
    • (2011) Free Rad Biol Med , vol.50 , pp. 567-75
    • Rains, J.L.1    Jain, S.K.2
  • 50
    • 77951197658 scopus 로고    scopus 로고
    • The natural protective mechanism against hyperglycemia in vascular endothelial cells roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor δ
    • Riahi Y, Sin-Malia Y, Cohen G, Alpert E, Gruzman A, Eckel J, Staels B, Guichardant M, Sasson S. (2010). The natural protective mechanism against hyperglycemia in vascular endothelial cells roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor δ. Diabetes 59:808-18.
    • (2010) Diabetes , vol.59 , pp. 808-18
    • Riahi, Y.1    Sin-Malia, Y.2    Cohen, G.3    Alpert, E.4    Gruzman, A.5    Eckel, J.6    Staels, B.7    Guichardant, M.8    Sasson, S.9
  • 52
    • 33748640374 scopus 로고    scopus 로고
    • Disparate effects of 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid in vascular endothelial and smooth muscle cells and in cardiomyocytes
    • DOI 10.1080/13813450600712035, PII JR24543773X5U317
    • Sasson S, Eckel J. (2006). Disparate effects of 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid in vascular endothelial and smooth muscle cells and in cardiomyocytes. Arch Physiol Biochem 112:119-29. (Pubitemid 44384780)
    • (2006) Archives of Physiology and Biochemistry , vol.112 , Issue.2 , pp. 119-129
    • Sasson, S.1    Eckel, J.2
  • 54
    • 35448976819 scopus 로고    scopus 로고
    • Tocotrienols in health and disease: The other half of the natural vitamin E family
    • DOI 10.1016/j.mam.2007.03.001, PII S0098299707000313, Vitamin E: An Overview of Major Research Directions
    • Sen CK, Khanna S, Roy S. (2007). Tocotrienols in health and disease: the other half of the natural vitamin E family. Mol Aspects Med 28:692-728. (Pubitemid 47625534)
    • (2007) Molecular Aspects of Medicine , vol.28 , Issue.5-6 , pp. 692-728
    • Sen, C.K.1    Khanna, S.2    Roy, S.3
  • 55
    • 1842430747 scopus 로고    scopus 로고
    • Amaranth squalene reduces serum and liver lipid levels in rats fed a cholesterol diet
    • Shin DH, Heo HJ, Lee YJ, Kim HK. (2004). Amaranth squalene reduces serum and liver lipid levels in rats fed a cholesterol diet. Br J Biomed Sci 61:11-4. (Pubitemid 38445333)
    • (2004) British Journal of Biomedical Science , vol.61 , Issue.1 , pp. 11-14
    • Shin, D.H.1    Heo, H.J.2    Lee, Y.J.3    Kim, H.K.4
  • 57
    • 0036987966 scopus 로고    scopus 로고
    • Vegetable lipids as components of functional foods
    • Stuchlik M, Zak S. (2002). Vegetable lipids as components of functional foods. Biomed Papers 146:3-10.
    • (2002) Biomed Papers , vol.146 , pp. 3-10
    • Stuchlik, M.1    Zak, S.2
  • 58
    • 0029988782 scopus 로고    scopus 로고
    • Heart rate variability. Standards of measurement, physiological interpretation, and clinical use
    • Task Force of the ES of Cardiology and the North AmS of Pacing and Electrophysiology
    • Task Force of the ES of Cardiology and the North AmS of Pacing and Electrophysiology. (1996). Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Eur Heart J 17:354-81.
    • (1996) Eur Heart J , vol.17 , pp. 354-81
  • 59
    • 0019439938 scopus 로고
    • Methods for increasing intensity of free radical oxidation of blood lipids containing components and its diagnostic value
    • Timirbulatov R, Seleznev E. (1986). Methods for increasing intensity of free radical oxidation of blood lipids containing components and its diagnostic value. Lab Delo (in Russian) 4:209-11.
    • (1986) Lab Delo (In Russian) , vol.4 , pp. 209-11
    • Timirbulatov, R.1    Seleznev, E.2
  • 60
    • 79953684026 scopus 로고    scopus 로고
    • Secreted proteins from adipose tissue and skeletal muscle-adipokines, myokines and adipose/muscle cross-talk
    • Trayhurn P, Christian A, Drevon CA, Eckel J. (2011). Secreted proteins from adipose tissue and skeletal muscle-adipokines, myokines and adipose/muscle cross-talk. Arch Physiol Biochem 117:47-56.
    • (2011) Arch Physiol Biochem , vol.117 , pp. 47-56
    • Trayhurn, P.1    Christian, A.2    Drevon, C.A.3    Eckel, J.4
  • 63
    • 77949842648 scopus 로고    scopus 로고
    • Water respiration-The basis of the living state
    • Voeikov VL, Del Giudice E. (2009). Water respiration-The basis of the living state. Water 1:52-75.
    • (2009) Water , vol.1 , pp. 52-75
    • Voeikov, V.L.1    Del Giudice, E.2
  • 65
    • 77956395196 scopus 로고    scopus 로고
    • Oxidative stress and vascular function: Implications for phramacologic treatment
    • Weseler AR, Bast A. (2010). Oxidative stress and vascular function: implications for phramacologic treatment. Curr Hypertens Rep 12:154-61.
    • (2010) Curr Hypertens Rep , vol.12 , pp. 154-61
    • Weseler, A.R.1    Bast, A.2
  • 67
    • 85015509131 scopus 로고    scopus 로고
    • Study of aerobic metabolism parameters and heart rate variability and their correlations in elite athletes: A modulatory effect of Amaranth oil
    • Yelisyeyeva O, Cherkas A, Semen K, Kaminskyy D, Lutsyk A. (2008a). Study of aerobic metabolism parameters and heart rate variability and their correlations in elite athletes: a modulatory effect of Amaranth oil. CEMED 3:293-307.
    • (2008) CEMED , vol.3 , pp. 293-307
    • Yelisyeyeva, O.1    Cherkas, A.2    Semen, K.3    Kaminskyy, D.4    Lutsyk, A.5
  • 68
    • 41049101193 scopus 로고    scopus 로고
    • The distribution of 4-hydroxynonenal-modified proteins in gastric mucosa of duodenal peptic ulcer patients
    • DOI 10.1080/10715760801975743, PII 791261873
    • Yelisyeyeva O, Cherkas A, Zarkovic K, Semen K, Kaminskyy D, Waeg G, Zarkovic N. (2008b). The distribution of 4-hydroxynonenalmodified proteins in gastric mucosa of duodenal peptic ulcer patients. Free Rad Res 42:205-11. (Pubitemid 351419906)
    • (2008) Free Radical Research , vol.42 , Issue.3 , pp. 205-211
    • Yelisyeyeva, O.1    Cherkas, A.2    Zarkovic, K.3    Semen, K.4    Kaminskyy, D.5    Waeg, G.6    Zarkovic, N.7
  • 70
    • 0043172469 scopus 로고    scopus 로고
    • 4-Hydroxynonenal as a bioactive marker of pathophysiological processes
    • DOI 10.1016/S0098-2997(03)00023-2
    • Zarkovic N. (2003). 4-Hydroxynonenal as a bioactive marker of pathophysiological processes. Mol Aspects Med 24:281-91. (Pubitemid 36945028)
    • (2003) Molecular Aspects of Medicine , vol.24 , Issue.4-5 , pp. 281-291
    • Zarkovic, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.