Thy1 associates with the cation channel subunit HCN4 in Adult Rat Retina

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 3, 2012, Pages 1696-1703

  Partida, Gloria J ^a   Stradleigh, Tyler W ^a   Ogata, Genki ^a   Godzdanker, Iv ^a   Ishida, Andrew T ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATION CHANNEL; CATION CHANNEL SUBUNIT HCN4; THY 1 ANTIGEN; TRANSCRIPTION FACTOR POU4F1; UNCLASSIFIED DRUG; HCN4 PROTEIN, RAT; POTASSIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; HYPERPOLARIZATION; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MEMBRANE CURRENT; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN ISOLATION; PROTEIN LOCALIZATION; RAT; RETINA; RETINA GANGLION CELL; WESTERN BLOTTING; ANIMAL; CYTOLOGY; LONG EVANS RAT; METABOLISM;

ANIMALS; ANTIGENS, THY-1; FEMALE; IMMUNOPRECIPITATION; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; RATS; RATS, LONG-EVANS; RETINAL GANGLION CELLS;

EID: 84860682776     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-9307     Document Type: Article

References (58)

1. Catallops I, Haas K, Cline HT. Postsynaptic CPG15 promotes synaptic maturation and presynaptic axon arbor elaboration in vivo. Nat Neurosci. 2000;3:1004-1011.
2. Saarma M. GDNF recruits the signaling crew into lipid rafts. Trends Neurosci. 2001;24:427-429.
3. Falk J, Bonnon C, Girault JA, Faivre-Sarrailh C. F3/contactin, a neuronal cell adhesion molecule implicated in axogenesis and myelination. Biol Cell. 2002;94:327-334.
4. Maekawa S, Iino S, Miyata S. Molecular characterization of the detergent-insoluble cholesterol-rich membrane microdomain (raft) of the central nervous system. Biochim Biophys Acta. 2003;1610: 261-270.
5. Yiu G, He Z. Glial inhibition of CNS axon regeneration. Nat Rev Neurosci. 2006;7:617-627.
6. Aguzzi A, Baumann F, Bremer J. The prion's elusive reason for being. Annu Rev Neurosci. 2008;31:439-477.
7. Barclay AN, Hydén H. Localization of the Thy-1 antigen in rat brain and spinal cord by immunofluorescence. J Neurochem. 1978;31: 1375-1391.
8. Williams AF, Gagnon J. Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin. Science. 1982;216:696-703.
9. Barres BA, Silverstein BE, Corey DP, Chun LL. Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning. Neuron. 1988;1:791-803.
10. Davis TL, Wiley RG. Anti-Thy-1 immunotoxin, OX7-saporin, destroys cerebellar Purkinje cells after intraventricular injection in rats. Brain Res. 1989;504:216-222.
11. Shoge K, Mishima HK, Mukai S, et al. Rat retinal ganglion cells culture enriched with the magnetic cell sorter. Neurosci Lett. 1999;259:111-114.
12. Wisden W, Cope D, Klausberger T, et al. Ectopic expression of the GABA(A) receptor alpha6 subunit in hippocampal pyramidal neurons produces extrasynaptic receptors and an increased tonic inhibition. Neuropharmacol. 2002;43:530-549.
13. Levene MJ, Dombeck DA, Kasischke KA, Molloy RP, Webb WW. In vivo multiphoton microscopy of deep brain tissue. J Neurophysiol. 2004;91:1908-1912.
14. Bannerman PG, Hahn A, Ramirez S, et al. Motor neuron pathology in experimental autoimmune encephalomyelitis: studies in THY1- YFP transgenic mice. Brain. 2005;128:1877-1886.
15. Kerrison JB, Duh EJ, Yu Y, Otteson DC, Zack DJ. A system for inducible gene expression in retinal ganglion cells. Invest Ophthalmol Vis Sci. 2005;46:2932-2939.
16. Barnstable CJ, Dräger UC. Thy-1 antigen: a ganglion cell specific marker in rodent retina. Neurosci. 1984;11:847-855.
17. Raymond ID, Vila A, Huynh UC, Brecha NC. Cyan fluorescent protein expression in ganglion and amacrine cells in a thy1-CFP transgenic mouse retina. Mol Vis. 2008;14:1559-1574.
18. Feng G, Mellor RH, Bernstein M, et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron. 2000;28:41-51.
19. Gastinger MJ, Kunselman AR, Conboy EE, Bronson SK, Barber AJ. Dendrite remodeling and other abnormalities in the retinal ganglion cells of Ins2 Akita diabetic mice. Invest Ophthalmol Vis Sci. 2008;49:2635-2642.
20. Mazzoni F, Novelli E, Strettoi E. Retinal ganglion cells survive and maintain normal dendritic morphology in a mouse model of inherited photoreceptor degeneration. J Neurosci. 2008;28:14282-14292.
21. Murata H, Aihara M, Chen Y-N, Ota T, Numaga J, Araie M. Imaging mouse retinal ganglion cells and their loss in vivo by a fundus camera in the normal and ischemia-reperfusion model. Invest Ophthalmol Vis Sci. 2008;49:5546-5552.
22. Leung CK, Weinreb RN. Experimental detection of retinal ganglion cell damage in vivo. Exp Eye Res. 2009;88:831-836.
23. Raymond ID, Pool AL, Vila A, Brecha NC. A Thy1-CFP DBA/2J mouse line with cyan fluorescent protein expression in retinal ganglion cells. Vis Neurosci. 2009;26:453-465.
24. Kim I-J, Zhang Y, Meister M, Sanes JR. Laminar restriction of retinal ganglion cell dendrites and axons: subtype-specific developmental patterns revealed with transgenic markers. J Neurosci. 2010;30: 1452-1462.
25. Morris RJ, Ritter MA. Association of Thy-1 cell surface differentiation antigen with certain connective tissues in vivo. Cell Tissue Res. 1980;206:459-475.
26. Bourguignon LY, Suchard SJ, Kalomiris EL. Lymphoma Thy-1 glycoprotein is linked to the cytoskeleton via a 4.1-like protein. J Cell Biol. 1986;103:2529-2540.
27. Stefanová I, Horejsí V, Ansotegui IJ, Knapp W, Stockinger H. GPI-anchored cell-surface molecules complexed to protein tyrosine kinases. Science. 1991;254:1016-1019.
28. Henke RC, Seeto GS, Jeffrey PL. Thy-1 and AvGp50 signal transduction complex in the avian nervous system: c-Fyn and G alpha I protein association and activation of signaling pathways. J Neurosci Res. 1997;49:655-670.
29. Hermosilla T, Muñoz D, Herrera-Molina R, et al. Direct Thy-1/ alphaVbeta3 integrin interaction mediates neuron to astrocyte communication. Biochim Biophys Acta. 2008;1783:1111-1120.
30. ir in adult rat retinal ganglion cells. J Neurophysiol. 2007;97:3790-3799.
31. Stradleigh TW, Ogata G, Partida GJ, et al. Colocalization of hyperpolarization- activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells. J Comp Neurol. 2011;519:2546-2573.
32. Santoro B, Tibbs GR. The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels. Ann N Y Acad Sci. 1999;868:741-764.
33. Beale R, Osborne NN. Localization of the Thy-1 antigen to the surfaces of rat retinal ganglion cells. Neurochem Int. 1982;4:587-595.
34. Müller F, Scholten A, Ivanova E, Haverkamp S, Kremmer E, Kaupp UB. HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminals. Eur J Neurosci. 2003; 17:2084-2096.
35. Oi H, Partida GJ, Lee SC, Ishida AT. HCN4-like immunoreactivity in rat retinal ganglion cells. Vis Neurosci. 2008;25:95-102.
36. Nadal-Nicolás FM, Jiménez-López M, Sobrado-Calvo P, et al. Brn3a as a marker of retinal ganglion cells: qualitative and quantitative time course studies in naive and optic nerve-injured retinas. Invest Ophthalmol Vis Sci. 2009;50:3860-3868.
37. Manders EMM, Verbeek FJ, Aten JA. Measurement of co-localization of objects in dual-colour confocal images. J Microscopy. 1993; 169:375-382.
38. Illing M, Molday LL, Molday RS. The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily. J Biol Chem. 1997;272:10303-10310.
39. + currents in cerebellar Purkinje cells. Neurobiol Dis. 2001;8:324-330.
40. Hering H, Lin CC, Sheng M. Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. J Neurosci. 2003;23:3262-3271.
41. Davies A, Kadurin I, Alvarez-Laviada A, et al. The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function. Proc Natl Acad Sci USA. 2010;107:1654-1659.
42. + channel stimulated by arachidonic acid and polyunsaturated fatty acids. EMBO J. 1998;17:3297-3308.
43. Brockway LM, Zhou ZH, Bubien JK, Jovov B, Benos DJ, Keyser KT. Rabbit retinal neurons and glia express a variety of ENaC/DEG subunits. Am J Physiol. 2002;283:C126-C134.
44. Jow GM, Jeng CJ. Differential localization of rat Eag1 and Eag2 potassium channels in the retina. Neurosci Lett. 2009;431:12-16.
45. Perry VH, Morris RJ, Raisman G. Is Thy-1 expressed only by ganglion cells and their axons in the retina and optic nerve? J Neurocytol. 1984;13:809-824.
46. Schlamp CL, Johnson EC, Li Y, Morrison JC, Nickells RW. Changes in Thy1 gene expression associated with damaged retinal ganglion cells. Mol Vis. 2001;7:192-201.
47. Perry VH. Evidence for an amacrine cell system in the ganglion cell layer of the rat retina. Neurosci. 1981;6:931-944.
48. Campbell DG, Gagnon J, Reid KB, Williams AF. Rat brain Thy-1 glycoprotein. The amino acid sequence, disulphide bonds and an unusual hydrophobic region. Biochem J. 1981;195:15-30.
49. Ilangumaran S, Hoessli DC. Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane. Biochem J. 1998;335:433-440.
50. Barbuti A, Gravante B, Riolfo M, Milanesi R, Terragni B, DiFrancesco D. Localization of pacemaker channels in lipid rafts regulates channel kinetics. Circ Res. 2004;94:1325-1331.
51. Brady JD, Rich TC, Le X, et al. Functional role of lipid raft microdomains in cyclic nucleotide-gated channel activation. Mol Pharmacol. 2004;65:503-511.
52. Nakano Y, Fujita M, Ogino K, et al. Biogenesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon-Beard neurons to respond to mechanosensory stimulation. Development. 2010;137:1689-1698.
53. Haeryfar SM, Hoskin DW. Thy-1: more than a mouse pan-T cell marker. J Immunol. 2004;173:3581-3588.
54. Whitaker GM, Angoli D, Nazzari H, Shigemoto R, Accili EA. HCN2 and HCN4 isoforms self-assemble and co-assemble with equal preference to form functional pacemaker channels. J Biol Chem. 2007;282:22900-22909.
55. Kamphuis W, Cailotto C, Dijk F, Bergen A, Buijs RM. Circadian expression of clock genes and clock-controlled genes in the rat retina. Biochem Biophys Res Comm. 2005;330:18-26.
56. Nosten-Bertrand M, Errington ML, Murphy KP, et al. Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1. Nature. 1996;379:826-829.
57. Mataruga A, Kremmer E, Müller F. Type 3a and type 3b OFF cone bipolar cells provide for the alternative rod pathway in the mouse retina. J Comp Neurol. 2007;502:1123-1137.
58. Simon PD, McConnell J, Zurakowski D, et al. Thy-1 is critical for normal retinal development. Dev Brain Res. 1999;117:219-223.