Studies on the synthesis of derivatives of marine-derived bostrycin and their structure-activity relationship against tumor cells

Marine Drugs

Volumn 10, Issue 4, 2012, Pages 932-952

  Chen, Hong ^a   Zhong, Lili ^a   Long, Yuhua ^b   Li, Jia ^a   Wu, Jueheng ^a,c   Liu, Lan ^a   Chen, Shengping ^a,c   Lin, Yongcheng ^a   Li, Mengfeng ^a,c   Zhu, Xun ^a,c   She, Zhigang ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SOUTH CHINA NORMAL UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Antitumor; Bostrycin; Derivatives; Structure activity relationship; Synthesis

Indexed keywords

1 O (HYDROXYMETHYL) 2,3 O (METHYLENE) BOSTRYCIN; 2,3 O (CARBONYL) BOSTRYCIN; 2,3 ORTHO O (3' METHYLBUT 2' ENYL) BOSTRYCIN; 2,3 ORTHO O (ISOPROPYLIDENE) BOSTRYCIN; 6 (2' HYDROXYETHYLAMINO) 6 DEMETHOXYBOSTRYCIN; 6 (4' METHYLPIPERIDIN 1 YL) 6 DEMETHOXYBOSTRYCIN; 6 (4' PHENYLPIPERIDIN 1 YL) 6 DEMETHOXYBOSTRYCIN; 6 (BENZYLAMINO) 6 DEMETHOXYBOSTRYCIN; 6 (METHYLAMINO) 6 DEMETHOXYBOSTRYCIN; 6 (N BUTYLAMINO) 6 DEMETHOXYBOSTRYCIN; 6 (N HEXYLAMINO) 6 DEMETHOXYBOSTRYCIN; 6 (N PROPYLAMINO) 6 DEMETHOXYBOSTRYCIN; 6 (P METHOXYBENZYLAMINO) 6 DEMETHOXYBOSTRYCIN; 6 (P METHOXYPHENYLAMINO) 6 DEMETHOXYBOSTRYCIN; 6 (PHENYLAMINO) 6 DEMETHOXYBOSTRYCIN; 6 (PIPERIDIN 1 YL) 6 DEMETHOXYBOSTRYCIN; 6 [(2'' HYDROXYETHOXY)ETHYLAMINO] 6 DEMETHOXYBOSTRYCIN; 6,7 (BUTAN 2',3' YL DITHIO) 6 DEMETHOXYBOSTRYCIN; 6,7 (ETHAN 1',2' YL DITHIO) 6 DEMETHOXYBOSTRYCIN; 6,7 BIS (ETHYLTHIO) 6 DEMETHOXYBOSTRYCIN; 6,7 BIS (N BUTYLTHIO) 6 DEMETHOXYBOSTRYCIN; 6,7 BIS (N HEXYLTHIO) 6 DEMETHOXYBOSTRYCIN; ANTHRAQUINONE DERIVATIVE; AUSTROCORTININ; BOSTRYCIN; DEOXYBOSTRYCIN; EPIRUBICIN; NIGROSPORIN; TETRAHYDROANTHRAQUINONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN A549; CELL STRAIN HCT116; CELL STRAIN HEPG2; CELL STRAIN MCF 10A; CELL STRAIN MCF 7; CELL STRAIN MDA MB 435; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MARINE SPECIES; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

EID: 84860642911     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md10040932     Document Type: Article

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