Sodium selenide toxicity is mediated by O2-dependent DNA breaks

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Peyroche, Gérald ^a,d   Saveanu, Cosmin ^b   Dauplais, Marc ^a   Lazard, Myriam ^a   Beuneu, François ^c   Decourty, Laurence ^b   Malabat, Christophe ^b   Jacquier, Alain ^b   Blanquet, Sylvain ^a   Plateau, Pierre ^a  

^a LABORATOIRE DE BIOCHIMIE   (France)

^b CNRS   (France)

^c LABORATOIRE DES SOLIDES IRRADIÉS   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; HYDROGEN SELENIDE; MANNITOL; OXYGEN; SELENIDE; SODIUM SELENIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; SELENIUM DERIVATIVE;

ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CHROMOSOME PAIRING; DNA DAMAGE; DNA FRAGMENTATION; DNA REPAIR; DNA STRAND BREAKAGE; DNA SUPERCOILING; DOUBLE STRANDED DNA BREAK; ELECTRON SPIN RESONANCE; EXCISION REPAIR; FUNGAL STRAIN; GENETIC SCREENING; HOMOLOGOUS RECOMBINATION; NONHUMAN; OPEN READING FRAME; POLYMERASE CHAIN REACTION; S PHASE CELL CYCLE CHECKPOINT; SACCHAROMYCES CEREVISIAE; YEAST CELL; AEROBIC METABOLISM; ANAEROBIC GROWTH; CELL DEATH; CHEMISTRY; CHROMOSOME ABERRATION; DRUG EFFECT; FUNGAL GENOME; G2 PHASE CELL CYCLE CHECKPOINT; GENE INACTIVATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HAPLOIDY; HYPERSENSITIVITY; METABOLISM; SINGLE STRANDED DNA BREAK;

SACCHAROMYCES CEREVISIAE;

AEROBIOSIS; ANAEROBIOSIS; CELL DEATH; CHROMOSOME ABERRATIONS; DNA BREAKS, SINGLE-STRANDED; G2 PHASE CELL CYCLE CHECKPOINTS; GENE KNOCKOUT TECHNIQUES; GENOME, FUNGAL; HAPLOIDY; HOMOLOGOUS RECOMBINATION; HYPERSENSITIVITY; MANNITOL; OXYGEN; SACCHAROMYCES CEREVISIAE; SELENIUM COMPOUNDS;

EID: 84860642417     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036343     Document Type: Article

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