Inhibitory effects of beta-tricalciumphosphate wear particles on osteocytes via apoptotic response and Akt inactivation

Toxicology

Volumn 297, Issue 1-3, 2012, Pages 57-67

  Zhang, Yun ^a,b   Yan, Ming ^c   Yu, Aiyue ^a   Mao, Hongjiao ^a   Zhang, Jinping ^a  

^a SHAOXING UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c HANGZHOU DIANZI UNIVERSITY   (China)

Author keywords

Akt signaling; Apoptosis; Osteocytes; Wear particles

Indexed keywords

BONE CEMENT; CALCIUM PHOSPHATE; DENTIN MATRIX PROTEIN 1; ENDOTOXIN; F ACTIN; INTERLEUKIN 1BETA; MESSENGER RNA; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SCLEROSTIN; SERINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE PROSTHESIS; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; ENZYME INACTIVATION; IN VITRO STUDY; INCUBATION TIME; MITOCHONDRION; MOUSE; NONHUMAN; OSTEOCYTE; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BIOCOMPATIBLE MATERIALS; CALCIUM PHOSPHATES; CELLS, CULTURED; HUMANS; OSTEOCYTES; OSTEOLYSIS; PARTICLE SIZE; PROTO-ONCOGENE PROTEINS C-AKT; RATS;

EID: 84860636406     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.04.002     Document Type: Article

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