-
1
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams J, Palombella VJ, Sausville EA, Johnson J, Destree A, Lazarus DD, Maas J, Pien CS, Prakash S, Elliott PJ (1999) Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res 59: 2615-2622.
-
(1999)
Cancer Res
, vol.59
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
Johnson, J.4
Destree, A.5
Lazarus, D.D.6
Maas, J.7
Pien, C.S.8
Prakash, S.9
Elliott, P.J.10
-
2
-
-
24944526723
-
Phase i trial of bortezomib and carboplatin in recurrent ovarian or primary peritoneal cancer
-
Aghajanian C, Dizon DS, Sabbatini P, Raizer JJ, Dupont J, Spriggs DR (2005) Phase I trial of bortezomib and carboplatin in recurrent ovarian or primary peritoneal cancer. J Clin Oncol 23: 5943-5949.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5943-5949
-
-
Aghajanian, C.1
Dizon, D.S.2
Sabbatini, P.3
Raizer, J.J.4
Dupont, J.5
Spriggs, D.R.6
-
3
-
-
0346336804
-
Treatment of multiple myeloma
-
Barlogie B Shaughnessy J, Tricot G, Jacobson J, Zangari M, Anaissie E, Walker R, Crowley J (2004) Treatment of multiple myeloma. Blood 103: 20-32.
-
(2004)
Blood
, vol.103
, pp. 20-32
-
-
Barlogie, B.1
Shaughnessy, J.2
Tricot, G.3
Jacobson, J.4
Zangari, M.5
Anaissie, E.6
Walker, R.7
Crowley, J.8
-
4
-
-
0037427122
-
NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells
-
Bentires-Alj M Barbu V, Fillet M, Chariot A, Relic B, Jacobs N, Gielen J, Merville MP, Bours V (2003) NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene 22: 90-97.
-
(2003)
Oncogene
, vol.22
, pp. 90-97
-
-
Bentires-Alj, M.1
Barbu, V.2
Fillet, M.3
Chariot, A.4
Relic, B.5
Jacobs, N.6
Gielen, J.7
Merville, M.P.8
Bours, V.9
-
5
-
-
33644916110
-
Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma
-
Berenson JR, Yang HH, Sadler K, Jarutirasarn SG, Vescio RA, Mapes R, Purner M, Lee SP, Wilson J, Morrison B, Adams J, Schenkein D, Swift R (2006) Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma. J Clin Oncol 24: 937-944.
-
(2006)
J Clin Oncol
, vol.24
, pp. 937-944
-
-
Berenson, J.R.1
Yang, H.H.2
Sadler, K.3
Jarutirasarn, S.G.4
Vescio, R.A.5
Mapes, R.6
Purner, M.7
Lee, S.P.8
Wilson, J.9
Morrison, B.10
Adams, J.11
Schenkein, D.12
Swift, R.13
-
6
-
-
0034875305
-
Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome
-
Bold RJ, Virudachalam S, McConkey DJ (2001) Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome. J Surg Res 100: 11-17.
-
(2001)
J Surg Res
, vol.100
, pp. 11-17
-
-
Bold, R.J.1
Virudachalam, S.2
McConkey, D.J.3
-
7
-
-
0038189917
-
Rationale for the treatment of solid tumors with the proteasome inhibitor bortezomib
-
Cusack JC (2003) Rationale for the treatment of solid tumors with the proteasome inhibitor bortezomib. Cancer Treat Rev 29 Suppl 1: 21-31.
-
(2003)
Cancer Treat Rev 29 Suppl
, vol.1
, pp. 21-31
-
-
Cusack, J.C.1
-
8
-
-
27144531388
-
Proteasome inhibitors can alter the signaling pathways and attenuate the P-glycoprotein-mediated multidrug resistance
-
Fujita T, Washio K, Takabatake D, Takahashi H, Yoshitomi S, Tsukuda K, Ishibe Y, Ogasawara Y, Doihara H, Shimizu N (2005) Proteasome inhibitors can alter the signaling pathways and attenuate the P-glycoprotein-mediated multidrug resistance. Int J Cancer 117: 670-682.
-
(2005)
Int J Cancer
, vol.117
, pp. 670-682
-
-
Fujita, T.1
Washio, K.2
Takabatake, D.3
Takahashi, H.4
Yoshitomi, S.5
Tsukuda, K.6
Ishibe, Y.7
Ogasawara, Y.8
Doihara, H.9
Shimizu, N.10
-
9
-
-
37549053213
-
Activity of bortezomib in adult de novo and relapsed acute myeloid leukemia
-
Gil L, Styczynski J, Dytfeld D, Debski R, Kazmierczak M, Kolodziej B, Rafinska B, Kubicka M, Nowicki A, Komarnicki M, Wysocki M (2007) Activity of bortezomib in adult de novo and relapsed acute myeloid leukemia. Anticancer Res 27: 4021-4025.
-
(2007)
Anticancer Res
, vol.27
, pp. 4021-4025
-
-
Gil, L.1
Styczynski, J.2
Dytfeld, D.3
Debski, R.4
Kazmierczak, M.5
Kolodziej, B.6
Rafinska, B.7
Kubicka, M.8
Nowicki, A.9
Komarnicki, M.10
Wysocki, M.11
-
10
-
-
0035300479
-
The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
-
Hideshima T, Richardson P, Chauhan D, Palombella VJ, Elliott PJ, Adams J, Anderson KC (2001) The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 61: 3071-3076.
-
(2001)
Cancer Res
, vol.61
, pp. 3071-3076
-
-
Hideshima, T.1
Richardson, P.2
Chauhan, D.3
Palombella, V.J.4
Elliott, P.J.5
Adams, J.6
Anderson, K.C.7
-
11
-
-
34250898562
-
NF-kappaB as a potential molecular target for cancer therapy
-
Lee CH, Jeon YT, Kim SH, Song YS (2007) NF-kappaB as a potential molecular target for cancer therapy. Biofactors 29: 19-35.
-
(2007)
Biofactors
, vol.29
, pp. 19-35
-
-
Lee, Ch.1
Jeon, Y.T.2
Kim, S.H.3
Song, Y.S.4
-
12
-
-
35548991085
-
Clinical significance of NF-kappaB continual activity and expression of WT1 and MDR1 in acute nonlymphocytic leukemia
-
Lei HY, Zhao XL (2007) [Clinical significance of NF-kappaB continual activity and expression of WT1 and MDR1 in acute nonlymphocytic leukemia]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 15: 253-257.
-
(2007)
Zhongguo Shi Yan Xue Ye Xue Za Zhi
, vol.15
, pp. 253-257
-
-
Lei, H.Y.1
Zhao, X.L.2
-
14
-
-
77950672853
-
The structure and functions of P-glycoprotein
-
Li Y, Yuan H, Yang K, Xu W, Tang W, Li X (2010) The structure and functions of P-glycoprotein. Curr Med Chem 17: 786-800.
-
(2010)
Curr Med Chem
, vol.17
, pp. 786-800
-
-
Li, Y.1
Yuan, H.2
Yang, K.3
Xu, W.4
Tang, W.5
Li, X.6
-
15
-
-
63449130437
-
Effect of Velcade on the gene expression profiles of K562 cells: Study of its molecular mechanism
-
Liao ZJ, Ma WL, Meng W, Liang S, Meng FY, Zheng WL (2008) [Effect of Velcade on the gene expression profiles of K562 cells: study of its molecular mechanism]. Nan Fang Yi Ke Da Xue Xue Bao 28: 373-376.
-
(2008)
Nan Fang Yi Ke da Xue Xue Bao
, vol.28
, pp. 373-376
-
-
Liao, Z.J.1
Ma, W.L.2
Meng, W.3
Liang, S.4
Meng, F.Y.5
Zheng, W.L.6
-
16
-
-
27244460815
-
Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies
-
Ludwig H, Khayat D, Giaccone G, Facon T (2005) Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies. Cancer 104: 1794-1807.
-
(2005)
Cancer
, vol.104
, pp. 1794-1807
-
-
Ludwig, H.1
Khayat, D.2
Giaccone, G.3
Facon, T.4
-
17
-
-
33845363835
-
A phase i and pharmacologic study of sequences of the proteasome inhibitor, bortezomib (PS-341, Velcade), in combination with paclitaxel and carboplatin in patients with advanced malignancies
-
Ma C, Mandrekar SJ, Alberts SR, Croghan GA, Jatoi A, Reid JM, Hanson LJ, Bruzek L, Tan AD, Pitot HC, Erlichman C, Wright JJ, Adjei AA (2007) A phase I and pharmacologic study of sequences of the proteasome inhibitor, bortezomib (PS-341, Velcade), in combination with paclitaxel and carboplatin in patients with advanced malignancies. Cancer Chemother Pharmacol 59: 207-215.
-
(2007)
Cancer Chemother Pharmacol
, vol.59
, pp. 207-215
-
-
Ma, C.1
Mandrekar, S.J.2
Alberts, S.R.3
Croghan, G.A.4
Jatoi, A.5
Reid, J.M.6
Hanson, L.J.7
Bruzek, L.8
Tan, A.D.9
Pitot, H.C.10
Erlichman, C.11
Wright, J.J.12
Adjei, A.A.13
-
18
-
-
0037342894
-
The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents
-
Ma MH, Yang HH, Parker K, Manyak S, Friedman JM, Altamirano C, Wu ZQ, Borad MJ, Frantzen M, Roussos E, Neeser J, Mikail A, Adams J, Sjak-Shie N, Vescio RA, Berenson JR (2003) The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin Cancer Res 9: 1136-1144.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1136-1144
-
-
Ma, M.H.1
Yang, H.H.2
Parker, K.3
Manyak, S.4
Friedman, J.M.5
Altamirano, C.6
Wu, Z.Q.7
Borad, M.J.8
Frantzen, M.9
Roussos, E.10
Neeser, J.11
Mikail, A.12
Adams, J.13
Sjak-Shie, N.14
Vescio, R.A.15
Berenson, J.R.16
-
20
-
-
33644785935
-
Phase i trial of bortezomib incombination with docetaxel in patients with advanced solid tumors
-
Messermith WA, Baker SD, Lassiter L, Sullivan RA, Dinh K, Almuete VI, Wright JJ, Donehower RC, Carducci MA, Armstrong DK (2006) Phase I trial of bortezomib incombination with docetaxel in patients with advanced solid tumors. Clin Cancer Res 12: 1270-1275.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1270-1275
-
-
Messermith, W.A.1
Baker, S.D.2
Lassiter, L.3
Sullivan, R.A.4
Dinh, K.5
Almuete, V.I.6
Wright, J.J.7
Donehower, R.C.8
Carducci, M.A.9
Armstrong, D.K.10
-
21
-
-
0037443551
-
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
-
Mitsiades N, Mitsiades CS, Richardson PG, Poulaki V, Tai YT, Chauhan D, Fanourakis G, Gu X, Bailey C, Joseph M, Libermann TA, Schlossman R, Munshi NC, Hideshima T, Anderson KC (2003) The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 101: 2377-2380.
-
(2003)
Blood
, vol.101
, pp. 2377-2380
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
Poulaki, V.4
Tai, Y.T.5
Chauhan, D.6
Fanourakis, G.7
Gu, X.8
Bailey, C.9
Joseph, M.10
Libermann, T.A.11
Schlossman, R.12
Munshi, N.C.13
Hideshima, T.14
Anderson, K.C.15
-
22
-
-
48249130925
-
Clinical implications of bortezomib in frontline treatment of newly-diagnosed multiple myeloma
-
Ohashi K (2008) [Clinical implications of bortezomib in frontline treatment of newly-diagnosed multiple myeloma]. Gan To Kagaku Ryoho 35: 1029-1032.
-
(2008)
Gan to Kagaku Ryoho
, vol.35
, pp. 1029-1032
-
-
Ohashi, K.1
-
23
-
-
20144387627
-
Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
-
Orlowski RZ, Voorhees PM, Garcia RA, Hall MD, Kudrik FJ, Allred T, Johri AR, Jones PE, Ivanova A, Van Deventer HW, Gabriel DA, Shea TC, Mitchell BS, Adams J, Esseltine DL, Trehu EG, Green M, Lehman MJ, Natoli S, Collins JM, Lindley CM, Dees EC (2005) Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 105: 3058-3065.
-
(2005)
Blood
, vol.105
, pp. 3058-3065
-
-
Orlowski, R.Z.1
Voorhees, P.M.2
Garcia, R.A.3
Hall, M.D.4
Kudrik, F.J.5
Allred, T.6
Johri, A.R.7
Jones, P.E.8
Ivanova, A.9
Van Deventer, H.W.10
Gabriel, D.A.11
Shea, T.C.12
Mitchell, B.S.13
Adams, J.14
Esseltine, D.L.15
Trehu, E.G.16
Green, M.17
Lehman, M.J.18
Natoli, S.19
Collins, J.M.20
Lindley, C.M.21
Dees, E.C.22
more..
-
25
-
-
33751563004
-
A phase i study of bortezomib plus irinotecan in patients with advanced solid tumors
-
Ryan DP, O'Neil BH, Supko JG, Rocha Lima CM, Dees EC, Appleman LJ, Clark J, Fidias P, Orlowski RZ, Kashala O, Eder JP, Cusack JC Jr. (2006) A phase I study of bortezomib plus irinotecan in patients with advanced solid tumors. Cancer 107: 2688-2697.
-
(2006)
Cancer
, vol.107
, pp. 2688-2697
-
-
Ryan, D.P.1
O'Neil, B.H.2
Supko, J.G.3
Rocha Lima, C.M.4
Dees, E.C.5
Appleman, L.J.6
Clark, J.7
Fidias, P.8
Orlowski, R.Z.9
Kashala, O.10
Eder, J.P.11
Cusack Jr., J.C.12
-
28
-
-
34250770091
-
A parallel dose-escalation study of weekly and twice-weekly bortezomib in combination with gemcitabine and cisplatin in the first-line treatment of patients with advanced solid tumors
-
Voortman J, Smit EF, Honeywell R, Kuenen BC, Peters GJ, van de Velde H, Giaccone G (2007) A parallel dose-escalation study of weekly and twice-weekly bortezomib in combination with gemcitabine and cisplatin in the first-line treatment of patients with advanced solid tumors. Clin Cancer Res 13: 3642-3651.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3642-3651
-
-
Voortman, J.1
Smit, E.F.2
Honeywell, R.3
Kuenen, B.C.4
Peters, G.J.5
Van De Velde, H.6
Giaccone, G.7
-
29
-
-
74049140877
-
Proteasome inhibitor induces apoptosis and influences the expression of Notch1 and NF-kappaB in multiple myeloma RPMI8226 cells
-
Wang H, Liu X, Xu B (2008) [Proteasome inhibitor induces apoptosis and influences the expression of Notch1 and NF-kappaB in multiple myeloma RPMI8226 cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16: 531-537.
-
(2008)
Zhongguo Shi Yan Xue Ye Xue Za Zhi
, vol.16
, pp. 531-537
-
-
Wang, H.1
Liu, X.2
Xu, B.3
-
31
-
-
0642378063
-
Overcoming drug resistance in multiple myeloma: The emergence of therapeutic approaches to induce apoptosis
-
Yang HH, Ma MH, Vescio RA, Berenson JR (2003) Overcoming drug resistance in multiple myeloma: the emergence of therapeutic approaches to induce apoptosis. J Clin Oncol 21: 4239-4247.
-
(2003)
J Clin Oncol
, vol.21
, pp. 4239-4247
-
-
Yang, H.H.1
Ma, M.H.2
Vescio, R.A.3
Berenson, J.R.4
|