메뉴 건너뛰기




Volumn 16, Issue 5, 2012, Pages 479-488

Immunoselected STRO-3+ mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs: Laboratory investigation

Author keywords

Degenerative disc disease; Disc degeneration; Disc matrix; Ovine model; Restoration; Sheep; STRO 3+ mesenchymal precursor cell

Indexed keywords

ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; BETA1 INTEGRIN; CD14 ANTIGEN; CD146 ANTIGEN; CD31 ANTIGEN; CD45 ANTIGEN; HEAT SHOCK PROTEIN 90; HERMES ANTIGEN; HYALURONIC ACID; N ACETYLGALACTOSAMINE 4 SULFATASE; PROTEOGLYCAN;

EID: 84860611366     PISSN: 15475654     EISSN: 15475646     Source Type: Journal    
DOI: 10.3171/2012.1.SPINE11852     Document Type: Article
Times cited : (80)

References (51)
  • 1
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • DOI 10.1182/blood-2004-04-1559
    • Aggarwal S, Pittenger MF: Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105:1815-1822, 2005 (Pubitemid 40223708)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 2
    • 0033554190 scopus 로고    scopus 로고
    • Epidemiological features of chronic low-back pain
    • Andersson GB: Epidemiological features of chronic low-back pain. Lancet 354:581-585, 1999
    • (1999) Lancet , vol.354 , pp. 581-585
    • Andersson, G.B.1
  • 3
    • 0005974192 scopus 로고
    • The innervation of intervertebral discs
    • Ghosh P (ed): Boca Raton: CRC Press
    • Bogduk N: The innervation of intervertebral discs, in Ghosh P (ed): The Biology of the Intervertebral Disc. Boca Raton: CRC Press, 1988, Vol I, pp 135-139
    • (1988) The Biology of the Intervertebral Disc , vol.1 , pp. 135-139
    • Bogduk, N.1
  • 4
    • 33645575610 scopus 로고    scopus 로고
    • Pathology and possible mechanisms of nervous system response to disc degeneration
    • Brisby H: Pathology and possible mechanisms of nervous system response to disc degeneration. J Bone Joint Surg Am 88 (Suppl 2):68-71, 2006
    • (2006) J Bone Joint Surg Am , vol.88 , Issue.SUPPL. 2 , pp. 68-71
    • Brisby, H.1
  • 5
    • 77954868507 scopus 로고    scopus 로고
    • The effect of running exercise on intervertebral disc extracellular matrix production in a rat model
    • Brisby H, Wei AQ, Molloy T, Chung SA, Murrell GA, Diwan AD: The effect of running exercise on intervertebral disc extracellular matrix production in a rat model. Spine (Phila Pa 1976) 35:1429-1436, 2010
    • (2010) Spine (Phila Pa 1976) , vol.35 , pp. 1429-1436
    • Brisby, H.1    Wei, A.Q.2    Molloy, T.3    Chung, S.A.4    Murrell, G.A.5    Diwan, A.D.6
  • 6
    • 0033982592 scopus 로고    scopus 로고
    • Beyond the good prognosis. Examination of an inception cohort of patients with chronic low back pain
    • Carey TS, Garrett JM, Jackman AM: Beyond the good prognosis. Examination of an inception cohort of patients with chronic low back pain. Spine (Phila Pa 1976) 25:115-120, 2000
    • (2000) Spine (Phila Pa 1976) , vol.25 , pp. 115-120
    • Carey, T.S.1    Garrett, J.M.2    Jackman, A.M.3
  • 7
    • 54149118562 scopus 로고    scopus 로고
    • Mesenchymal stem cells in arthritic diseases
    • Chen FH, Tuan RS: Mesenchymal stem cells in arthritic diseases. Arthritis Res Ther 10:223, 2008
    • (2008) Arthritis Res Ther , vol.10 , pp. 223
    • Chen, F.H.1    Tuan, R.S.2
  • 8
    • 79957807754 scopus 로고    scopus 로고
    • Stem cell horizons in intervertebral disc degeneration
    • Ciacci J, Ho A, Ames CP, Jandial R: Stem cell horizons in intervertebral disc degeneration. Stem Cells Cloning 1:31-39, 2008
    • (2008) Stem Cells Cloning , vol.1 , pp. 31-39
    • Ciacci, J.1    Ho, A.2    Ames, C.P.3    Jandial, R.4
  • 9
    • 37349041034 scopus 로고    scopus 로고
    • A systematic review of low back pain cost of illness studies in the United States and internationally
    • DOI 10.1016/j.spinee.2007.10.005, PII S1529943007008984
    • Dagenais S, Caro J, Haldeman S: A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 8:8-20, 2008 (Pubitemid 350299273)
    • (2008) Spine Journal , vol.8 , Issue.1 , pp. 8-20
    • Dagenais, S.1    Caro, J.2    Haldeman, S.3
  • 10
    • 0030790455 scopus 로고    scopus 로고
    • Nerve ingrowth into diseased intervertebral disc in chronic back pain
    • DOI 10.1016/S0140-6736(97)02135-1
    • Freemont AJ, Peacock TE, Goupille P, Hoyland JA, O'Brien J, Jayson MI: Nerve ingrowth into diseased intervertebral disc in chronic back pain. Lancet 350:178-181, 1997 (Pubitemid 27303625)
    • (1997) Lancet , vol.350 , Issue.9072 , pp. 178-181
    • Freemont, A.J.1    Peacock, T.E.2    Goupille, P.3    Hoyland, J.A.4    O'Brien, J.5    Jayson, M.I.V.6
  • 11
    • 70349845897 scopus 로고    scopus 로고
    • Intervertebral disc repair using adipose tissue-derived stem and regenerative cells: Experiments in a canine model
    • Ganey T, Hutton WC, Moseley T, Hedrick M, Meisel HJ: Intervertebral disc repair using adipose tissue-derived stem and regenerative cells: experiments in a canine model. Spine (Phila Pa 1976) 34:2297-2304, 2009
    • (2009) Spine (Phila Pa 1976) , vol.34 , pp. 2297-2304
    • Ganey, T.1    Hutton, W.C.2    Moseley, T.3    Hedrick, M.4    Meisel, H.J.5
  • 12
    • 77956198493 scopus 로고    scopus 로고
    • Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: Preliminary study in an ovine model
    • Goldschlager T, Ghosh P, Zannettino A, Gronthos S, Rosenfeld JV, Itescu S, et al: Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: preliminary study in an ovine model. Neurosurg Focus 28(6):E4, 2010
    • (2010) Neurosurg Focus , vol.28 , Issue.6
    • Goldschlager, T.1    Ghosh, P.2    Zannettino, A.3    Gronthos, S.4    Rosenfeld, J.V.5    Itescu, S.6
  • 13
    • 79952898485 scopus 로고    scopus 로고
    • A comparison of mesenchymal precursor cells and amnion epithelial cells for enhancing cervical interbody fusion in an ovine model
    • Goldschlager T, Ghosh P, Zannettino A, Williamson M, Rosenfeld JV, Itescu S, et al: A comparison of mesenchymal precursor cells and amnion epithelial cells for enhancing cervical interbody fusion in an ovine model. Neurosurgery 68:1025-1035, 2011
    • (2011) Neurosurgery , vol.68 , pp. 1025-1035
    • Goldschlager, T.1    Ghosh, P.2    Zannettino, A.3    Williamson, M.4    Rosenfeld, J.V.5    Itescu, S.6
  • 15
    • 37549018854 scopus 로고    scopus 로고
    • A novel monoclonal antibody (STRO-3) identifies an isoform of tissue nonspecific alkaline phosphatase expressed by multipotent bone marrow stromal stem cells
    • Gronthos S, Fitter S, Diamond P, Simmons PJ, Itescu S, Zannettino AC: A novel monoclonal antibody (STRO-3) identifies an isoform of tissue nonspecific alkaline phosphatase expressed by multipotent bone marrow stromal stem cells. Stem Cells Dev 16:953-963, 2007
    • (2007) Stem Cells Dev , vol.16 , pp. 953-963
    • Gronthos, S.1    Fitter, S.2    Diamond, P.3    Simmons, P.J.4    Itescu, S.5    Zannettino, A.C.6
  • 16
    • 70450209662 scopus 로고    scopus 로고
    • Heat shock protein-90 beta is expressed at the surface of multipotential mesenchymal precursor cells: Generation of a novel monoclonal antibody, STRO-4, with specificity for mesenchymal precursor cells from human and ovine tissues
    • Gronthos S, McCarty R, Mrozik K, Fitter S, Paton S, Menicanin D, et al: Heat shock protein-90 beta is expressed at the surface of multipotential mesenchymal precursor cells: generation of a novel monoclonal antibody, STRO-4, with specificity for mesenchymal precursor cells from human and ovine tissues. Stem Cells Dev 18:1253-1262, 2009
    • (2009) Stem Cells Dev , vol.18 , pp. 1253-1262
    • Gronthos, S.1    McCarty, R.2    Mrozik, K.3    Fitter, S.4    Paton, S.5    Menicanin, D.6
  • 17
    • 79952117425 scopus 로고    scopus 로고
    • Methods for the purification and characterization of human adipose-derived stem cells
    • Gronthos S, Zannettino AC: Methods for the purification and characterization of human adipose-derived stem cells. Methods Mol Biol 702:109-120, 2011
    • (2011) Methods Mol Biol , vol.702 , pp. 109-120
    • Gronthos, S.1    Zannettino, A.C.2
  • 19
    • 64049111281 scopus 로고    scopus 로고
    • Transplantation of human mesenchymal stems cells into intervertebral discs in a xenogeneic porcine model
    • Henriksson HB, Svanvik T, Jonsson M, Hagman M, Horn M, Lindahl A, et al: Transplantation of human mesenchymal stems cells into intervertebral discs in a xenogeneic porcine model. Spine (Phila Pa 1976) 34:141-148, 2009
    • (2009) Spine (Phila Pa 1976) , vol.34 , pp. 141-148
    • Henriksson, H.B.1    Svanvik, T.2    Jonsson, M.3    Hagman, M.4    Horn, M.5    Lindahl, A.6
  • 20
    • 43649093152 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells in a canine disc degeneration model
    • Hiyama A, Mochida J, Iwashina T, Omi H, Watanabe T, Serigano K, et al: Transplantation of mesenchymal stem cells in a canine disc degeneration model. J Orthop Res 26:589-600, 2008
    • (2008) J Orthop Res , vol.26 , pp. 589-600
    • Hiyama, A.1    Mochida, J.2    Iwashina, T.3    Omi, H.4    Watanabe, T.5    Serigano, K.6
  • 21
    • 77957688083 scopus 로고    scopus 로고
    • Enhancement of intervertebral disc cell senescence by WNT/&βετα;-catenin signaling-induced matrix metalloproteinase expression
    • Hiyama A, Sakai D, Risbud MV, Tanaka M, Arai F, Abe K, et al: Enhancement of intervertebral disc cell senescence by WNT/&βετα;- catenin signaling-induced matrix metalloproteinase expression. Arthritis Rheum 62:3036-3047, 2010
    • (2010) Arthritis Rheum , vol.62 , pp. 3036-3047
    • Hiyama, A.1    Sakai, D.2    Risbud, M.V.3    Tanaka, M.4    Arai, F.5    Abe, K.6
  • 23
    • 1842733015 scopus 로고    scopus 로고
    • The use of intradiscal steroid therapy for lumbar spinal discogenic pain: A randomized controlled trial
    • Khot A, Bowditch M, Powell J, Sharp D: The use of intradiscal steroid therapy for lumbar spinal discogenic pain: a randomized controlled trial. Spine (Phila Pa 1976) 29:833-837, 2004
    • (2004) Spine (Phila Pa 1976) , vol.29 , pp. 833-837
    • Khot, A.1    Bowditch, M.2    Powell, J.3    Sharp, D.4
  • 24
    • 67749114451 scopus 로고    scopus 로고
    • Senescent cells in the intervertebral disc: Numbers and mechanisms
    • Kletsas D: Senescent cells in the intervertebral disc: numbers and mechanisms. Spine J 9:677-678, 2009
    • (2009) Spine J , vol.9 , pp. 677-678
    • Kletsas, D.1
  • 25
    • 61449135224 scopus 로고    scopus 로고
    • An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue
    • Le Maitre CL, Baird P, Freemont AJ, Hoyland JA: An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue. Arthritis Res Ther 11:R20, 2009
    • (2009) Arthritis Res Ther , vol.11
    • Le Maitre, C.L.1    Baird, P.2    Freemont, A.J.3    Hoyland, J.A.4
  • 27
    • 0001954556 scopus 로고
    • Nutrition and metabolism of the intervertebral disc
    • Ghosh P (ed): Boca Raton: CRC Press
    • Maroudas A: Nutrition and metabolism of the intervertebral disc, in Ghosh P (ed): The Biology of the Intervertebral Disc. Boca Raton: CRC Press, 1988, Vol 2, pp 1-37
    • (1988) The Biology of the Intervertebral Disc , vol.2 , pp. 1-37
    • Maroudas, A.1
  • 28
    • 13444302219 scopus 로고    scopus 로고
    • A novel rabbit model of mild, reproducible disc degeneration by an anulus needle puncture: Correlation between the degree of disc injury and radiological and histological appearances of disc degeneration
    • Masuda K, Aota Y, Muehleman C, Imai Y, Okuma M, Thonar EJ, et al: A novel rabbit model of mild, reproducible disc degeneration by an anulus needle puncture: correlation between the degree of disc injury and radiological and histological appearances of disc degeneration. Spine (Phila Pa 1976) 30:5-14, 2005
    • (2005) Spine (Phila Pa 1976) , vol.30 , pp. 5-14
    • Masuda, K.1    Aota, Y.2    Muehleman, C.3    Imai, Y.4    Okuma, M.5    Thonar, E.J.6
  • 29
    • 0026928566 scopus 로고
    • A longitudinal study of the matrix changes induced in the intervertebral disc by surgical damage to the annulus fibrosus
    • Melrose J, Ghosh P, Taylor TK, Hall A, Osti OL, Vernon-Roberts B, et al: A longitudinal study of the matrix changes induced in the intervertebral disc by surgical damage to the annulus fibrosus. J Orthop Res 10:665-676, 1992
    • (1992) J Orthop Res , vol.10 , pp. 665-676
    • Melrose, J.1    Ghosh, P.2    Taylor, T.K.3    Hall, A.4    Osti, O.L.5    Vernon-Roberts, B.6
  • 30
    • 0037096932 scopus 로고    scopus 로고
    • Increased nerve and blood vessel ingrowth associated with proteoglycan depletion in an ovine anular lesion model of experimental disc degeneration
    • Melrose J, Roberts S, Smith S, Menage J, Ghosh P: Increased nerve and blood vessel ingrowth associated with proteoglycan depletion in an ovine anular lesion model of experimental disc degeneration. Spine (Phila Pa 1976) 27:1278-1285, 2002
    • (2002) Spine (Phila Pa 1976) , vol.27 , pp. 1278-1285
    • Melrose, J.1    Roberts, S.2    Smith, S.3    Menage, J.4    Ghosh, P.5
  • 31
    • 50949105736 scopus 로고    scopus 로고
    • Chondrogenesis, bone morphogenetic protein-4 and mesenchymal stem cells
    • Miljkovic ND, Cooper GM, Marra KG: Chondrogenesis, bone morphogenetic protein-4 and mesenchymal stem cells. Osteoarthritis Cartilage 16:1121-1130, 2008
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 1121-1130
    • Miljkovic, N.D.1    Cooper, G.M.2    Marra, K.G.3
  • 32
    • 33646552691 scopus 로고    scopus 로고
    • Treatment of painful advanced internal lumbar disc derangement with intradiscal injection of hypertonic dextrose
    • Miller MR, Mathews RS, Reeves KD: Treatment of painful advanced internal lumbar disc derangement with intradiscal injection of hypertonic dextrose. Pain Physician 9:115-121, 2006
    • (2006) Pain Physician , vol.9 , pp. 115-121
    • Miller, M.R.1    Mathews, R.S.2    Reeves, K.D.3
  • 33
    • 78049475050 scopus 로고    scopus 로고
    • The role of intradiscal steroids in the treatment of discogenic low back pain
    • Muzin S, Isaac Z, Walker J III: The role of intradiscal steroids in the treatment of discogenic low back pain. Curr Rev Musculoskelet Med 1:103-107, 2008
    • (2008) Curr Rev Musculoskelet Med , vol.1 , pp. 103-107
    • Muzin, S.1    Isaac, Z.2    Walker III, J.3
  • 34
    • 0026792914 scopus 로고
    • Annular tears and disc degeneration in the lumbar spine. A post-mortem study of 135 discs
    • Osti OL, Vernon-Roberts B, Moore R, Fraser RD: Annular tears and disc degeneration in the lumbar spine. A post-mortem study of 135 discs. J Bone Joint Surg Br 74:678-682, 1992
    • (1992) J Bone Joint Surg Br , vol.74 , pp. 678-682
    • Osti, O.L.1    Vernon-Roberts, B.2    Moore, R.3    Fraser, R.D.4
  • 35
    • 77349089226 scopus 로고    scopus 로고
    • A randomized placebo-controlled trial of intradiscal methylene blue injection for the treatment of chronic discogenic low back pain
    • Peng B, Pang X, Wu Y, Zhao C, Song X: A randomized placebo-controlled trial of intradiscal methylene blue injection for the treatment of chronic discogenic low back pain. Pain 149:124-129, 2010
    • (2010) Pain , vol.149 , pp. 124-129
    • Peng, B.1    Pang, X.2    Wu, Y.3    Zhao, C.4    Song, X.5
  • 36
    • 0034650665 scopus 로고    scopus 로고
    • A cross-sectional study correlating lumbar spine degeneration with disability and pain
    • Peterson CK, Bolton JE, Wood AR: A cross-sectional study correlating lumbar spine degeneration with disability and pain. Spine (Phila Pa 1976) 25:218-223, 2000
    • (2000) Spine (Phila Pa 1976) , vol.25 , pp. 218-223
    • Peterson, C.K.1    Bolton, J.E.2    Wood, A.R.3
  • 38
    • 77956621223 scopus 로고    scopus 로고
    • Reparative effects of allogeneic mesenchymal precursor cells delivered transendocardially in experimental nonischemic cardiomyopathy
    • Psaltis PJ, Carbone A, Nelson AJ, Lau DH, Jantzen T, Manavis J, et al: Reparative effects of allogeneic mesenchymal precursor cells delivered transendocardially in experimental nonischemic cardiomyopathy. JACC Cardiovasc Interv 3:974-983, 2010
    • (2010) JACC Cardiovasc Interv , vol.3 , pp. 974-983
    • Psaltis, P.J.1    Carbone, A.2    Nelson, A.J.3    Lau, D.H.4    Jantzen, T.5    Manavis, J.6
  • 39
    • 77950801859 scopus 로고    scopus 로고
    • Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrow-derived mesenchymal cell populations
    • Psaltis PJ, Paton S, See F, Arthur A, Martin S, Itescu S, et al: Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrow-derived mesenchymal cell populations. J Cell Physiol 223:530-540, 2010
    • (2010) J Cell Physiol , vol.223 , pp. 530-540
    • Psaltis, P.J.1    Paton, S.2    See, F.3    Arthur, A.4    Martin, S.5    Itescu, S.6
  • 40
    • 26844531456 scopus 로고    scopus 로고
    • Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc
    • DOI 10.1016/j.biomaterials.2005.06.038, PII S0142961205006125, Biomaterials for Spinal Applications
    • Sakai D, Mochida J, Iwashina T, Hiyama A, Omi H, Imai M, et al: Regenerative effects of transplanting mesenchymal stem cells embedded in atelocollagen to the degenerated intervertebral disc. Biomaterials 27:335-345, 2006 (Pubitemid 41457236)
    • (2006) Biomaterials , vol.27 , Issue.3 , pp. 335-345
    • Sakai, D.1    Mochida, J.2    Iwashina, T.3    Hiyama, A.4    Omi, H.5    Imai, M.6    Nakai, T.7    Ando, K.8    Hotta, T.9
  • 41
    • 27644541907 scopus 로고    scopus 로고
    • Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: Potential and limitations for stem cell therapy in disc regeneration
    • Sakai D, Mochida J, Iwashina T, Watanabe T, Nakai T, Ando K, et al: Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration. Spine (Phila Pa 1976) 30:2379-2387, 2005
    • (2005) Spine (Phila Pa 1976) , vol.30 , pp. 2379-2387
    • Sakai, D.1    Mochida, J.2    Iwashina, T.3    Watanabe, T.4    Nakai, T.5    Ando, K.6
  • 42
    • 0035282379 scopus 로고    scopus 로고
    • Effects of chondroitinase ABC on intradiscal pressure in sheep: An in vivo study
    • Sasaki M, Takahashi T, Miyahara K, Hirose T: Effects of chondroitinase ABC on intradiscal pressure in sheep: an in vivo study. Spine (Phila Pa 1976) 26:463-468, 2001
    • (2001) Spine (Phila Pa 1976) , vol.26 , pp. 463-468
    • Sasaki, M.1    Takahashi, T.2    Miyahara, K.3    Hirose, T.4
  • 43
    • 77957203095 scopus 로고    scopus 로고
    • Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model
    • Serigano K, Sakai D, Hiyama A, Tamura F, Tanaka M, Mochida J: Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model. J Orthop Res 28:1267-1275, 2010
    • (2010) J Orthop Res , vol.28 , pp. 1267-1275
    • Serigano, K.1    Sakai, D.2    Hiyama, A.3    Tamura, F.4    Tanaka, M.5    Mochida, J.6
  • 44
    • 0042306316 scopus 로고    scopus 로고
    • Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp
    • Shi S, Gronthos S: Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. J Bone Miner Res 18:696-704, 2003 (Pubitemid 36899319)
    • (2003) Journal of Bone and Mineral Research , vol.18 , Issue.4 , pp. 696-704
    • Shi, S.1    Gronthos, S.2
  • 45
    • 33744513898 scopus 로고    scopus 로고
    • Age-related impairment of mesenchymal progenitor cell function
    • DOI 10.1111/j.1474-9726.2006.00213.x
    • Stolzing A, Scutt A: Age-related impairment of mesenchymal progenitor cell function. Aging Cell 5:213-224, 2006 (Pubitemid 43809939)
    • (2006) Aging Cell , vol.5 , Issue.3 , pp. 213-224
    • Stolzing, A.1    Scutt, A.2
  • 47
    • 0037963685 scopus 로고    scopus 로고
    • Adult mesenchymal stem cells and cell-based tissue engineering
    • Tuan RS, Boland G, Tuli R: Adult mesenchymal stem cells and cell-based tissue engineering. Arthritis Res Ther 5:32-45, 2003 (Pubitemid 36849748)
    • (2003) Arthritis Research and Therapy , vol.5 , Issue.1 , pp. 32-45
    • Tuan, R.S.1    Boland, G.2    Tuli, R.3
  • 48
    • 77949820578 scopus 로고    scopus 로고
    • Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells
    • Watanabe T, Sakai D, Yamamoto Y, Iwashina T, Serigano K, Tamura F, et al: Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells. J Orthop Res 28:623-630, 2010
    • (2010) J Orthop Res , vol.28 , pp. 623-630
    • Watanabe, T.1    Sakai, D.2    Yamamoto, Y.3    Iwashina, T.4    Serigano, K.5    Tamura, F.6
  • 49
    • 77952428710 scopus 로고    scopus 로고
    • Disc regeneration therapy using marrow mesenchymal cell transplantation: A report of two case studies
    • Yoshikawa T, Ueda Y, Miyazaki K, Koizumi M, Takakura Y: Disc regeneration therapy using marrow mesenchymal cell transplantation: a report of two case studies. Spine (Phila Pa1976) 35:E475-E480, 2010
    • (2010) Spine (Phila Pa1976) , vol.35
    • Yoshikawa, T.1    Ueda, Y.2    Miyazaki, K.3    Koizumi, M.4    Takakura, Y.5
  • 50
    • 37049027711 scopus 로고    scopus 로고
    • -/glycophorin-A- bone marrow cells
    • DOI 10.3324/haematol.11691
    • Zannettino AC, Paton S, Kortesidis A, Khor F, Itescu S, Gronthos S: Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34 /CD45(-)/glycophorin-A-bone marrow cells. Haematologica 92:1707-1708, 2007 (Pubitemid 350248254)
    • (2007) Haematologica , vol.92 , Issue.12 , pp. 1707-1708
    • Zannettino, A.C.W.1    Paton, S.2    Kortesidis, A.3    Khor, F.4    Itescu, S.5    Gronthos, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.