Aberrant intestinal stem cell lineage dynamics in Peutz-Jeghers syndrome and familial adenomatous polyposis consistent with protracted clonal evolution in the crypt

Gut

Volumn 61, Issue 6, 2012, Pages 839-846

  Langeveld, Danielle ^a,b   Jansen, Marnix ^b   De Boer, D V ^a   Van Sprundel, Mariska ^a   Brosens, Lodewijk A A ^a   Morsink, Folkert H ^a   Giardiello, Francis M ^c   Offerhaus, G Johan A ^a,b   De Leng, Wendy W J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE LKB1;

ADENOMATOUS POLYP; ADOLESCENT; ADULT; AGED; ARTICLE; CELL ISOLATION; CELL LINEAGE; CHILD; CLINICAL ARTICLE; COLON MUCOSA; CONTROLLED STUDY; CRYPT CELL; DNA METHYLATION; GENE ACTIVITY; GENE FUNCTION; GENE LOSS; GENE MUTATION; GENETIC VARIABILITY; GERM LINE; HOMEOBOX; HUMAN; HUMAN CELL; INTESTINE CELL; LKB1 GENE; MOLECULAR CLONING; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; ONCOGENE; PEUTZ JEGHERS SYNDROME; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCHOOL CHILD;

ADENOMATOUS POLYPOSIS COLI; ADOLESCENT; ADULT; AGED; CASE-CONTROL STUDIES; CELL LINEAGE; CHILD; DNA METHYLATION; HUMANS; INTESTINAL MUCOSA; MIDDLE AGED; MUTATION; PEUTZ-JEGHERS SYNDROME; PROTEIN-SERINE-THREONINE KINASES; STEM CELLS; YOUNG ADULT;

EID: 84860581329     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2011-300622     Document Type: Article

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