Polylysine copolymers for gene delivery

Cold Spring Harbor Protocols

Volumn 7, Issue 4, 2012, Pages 433-438

  Kim, Sung Wan ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; COPOLYMER; DEXTRAN; EPIDERMAL GROWTH FACTOR; GALACTOSE; HISTIDINE; IMIDAZOLE; LACTOSE; LOW DENSITY LIPOPROTEIN; MACROGOL; MANNOSE; PEPTIDE; POLYLYSINE COPOLYMER; TRANSFERRIN; UNCLASSIFIED DRUG; DNA; MACROGOL DERIVATIVE; POLYLYSINE;

ANIMAL CELL; ARTICLE; CONJUGATION; DNA TRANSFECTION; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIPID BILAYER; MOUSE; NONHUMAN; PROTEIN CONFORMATION; TEMPERATURE; TOXICITY; ANIMAL; CELL LINE; CHEMICAL PHENOMENA; CHEMISTRY; GENE TRANSFER; METABOLISM;

ANIMALS; CELL LINE; DNA; GENE TRANSFER TECHNIQUES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; POLYETHYLENE GLYCOLS; POLYLYSINE;

EID: 84860578667     PISSN: 19403402     EISSN: 15596095     Source Type: Journal    
DOI: 10.1101/pdb.ip068619     Document Type: Article

References (50)

1. Affleck DG, Yu L, Bull DA, Bailey SH, Kim SW. 2001. Augmentation of myocardial transfection using TerplexDNA: A novel gene delivery system. Gene Ther 8: 349-353.
2. Bikram M, Ahn CH, Chae SY, Lee M, Yockman JW, Kim SW. 2003. Novel biodegradable PEG-PLL-His multiblock copolymers for nonviral carrier mediated gene therapy. Mol Ther 1: S221.
3. Buschle M, Cotton M, Kirlappos H, Mechtler K, Schaffner G, Zauner W, Birnstiel ML, Wagner E. 1995. Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex. Hum Gene Ther 6: 753-761.
4. Carroll D. 1972a. Complexes of polylysine with polyuridylic acid and other polynuceotides. Biochemistry 11: 426-433.
5. Carroll D. 1972b. Optical properties of deoxyribonucleic acid-polylysine complexes. Biochemistry 11: 421-426.
6. Chan CK, Jans DA. 1999. Enhancement of polylysine-mediated transferrinfection by nuclear localization sequences: Polylysine does not function as a nuclear localization sequence. Hum Gene Ther 10: 1695-1702.
7. Chan CK, Senden T, Jans DA. 2000. Supramolecular structure and nuclear targeting efficiency determine the enhancement of transfection by modified polylysines. Gene Ther 7: 1690-1697.
8. Choi YH, Liu F, Park J, Kim SW. 1998a. Lactose-poly(ethylene glycol)-grafted poly-L-lysine as hepatoma cell-targeted gene carrier. Bioconjug Chem 9: 708-718.
9. Choi YH, Liu F, Kim JS, Choi YK, Park JS, Kim SW. 1998b. Polyethylene glycol-grafted poly L-lysine as polymeric gene carrier. J Control Release 54: 39-48.
10. Choi YH, Liu F, Choi JS, Kim SW, Park JS. 1999. Characterization of a targeted gene carrier, lactose-polyethylene glycol-grafted poly-L-lysine and its complex with plasmid DNA. Hum Gene Ther 10: 2657-2665.
11. Curiel DT, Agarway S, Wagner E, Cotton M. 1991. Adenovirus enhancement of transferrin-polylysine-mediated gene delivery. Proc Natl Acad Sci 88: 8850-8854.
12. Dekie L, Toncheva V, Dubruel P, Schacht EH, Barrett L, Seymour LW. 2000. Poly-L-glutamic acid derivatives as vectors for gene therapy. J Control Release 65: 187-202.
13. de Marco G, Bogdanov A, Marecos E, Moore A, Simonova M, Weissleder R. 1998. MR imaging of gene delivery to the central nervous system with an artificial vector. Radiology 208: 65-71.
14. Dunlap DD, Maggi A, Soria MR, Monaco L. 1997. Nanoscopic structure of DNA condensed for gene delivery. Nucleic Acids Res 25: 3095-3101.
15. Erbacher P, Bousser MT, Raimond J, Monsigny M, Midoux P, Roche AC. 1996. Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte-derived macrophages. Hum Gene Ther 7: 721-729.
16. Gad AE, Silver BL, Eytan GD. 1982. Polycation-induced fusion of negatively charged vesicles. Biochim Biophys Acta 690: 124-132.
17. Hartmann W, Galla HJ. 1978. Binding of polylysine to charged bilayer membranes: Molecular organization of a lipid peptide complex. Biochim Biophys Acta 509: 474-490.
18. Kawai S, Nishizawa M. 1984. New procedure for DNA transfection with polycation and dimethyl sulfoxide. Mol Cell Biol 4: 1172-1174.
19. Kim JS, Maruyama A, Akaike T, Kim SW. 1998. Terplex DNA delivery system as a gene carrier. Pharm Res 15: 116-121.
20. Kim JS, Maruyama A, Akaike T, Kim SW. 2000. Non-viral gene delivery strategies for enhanced cellular uptake. Biomaterials and drug delivery toward new millenium (ed. Park KD, et al.), pp. 237-247. Han Rim Won Publishing, Seoul, South Korea.
21. Kim JS, Maruyama A, Akaike T, Kim SW. 1997. In vitro gene expression on smooth muscle cells using a terplex delivery system. J Control Release 47: 51-59.
22. Koh JJ, Ko KS, Lee M, Han S, Park JS, Kim SW. 2000. Degradable polymeric carrier for the delivery of IL-10 plasmid DNA to prevent autoimmune insulitis of NOD mice. Gene Ther 7: 2099-2104.
23. Laemmli UK. 1975. Characterization of DNA condensates induced by poly (ethylene oxide) and polylysine. Proc Natl Acad Sci 72: 4288-4292.
24. Lentz MJ, Kim SW. 1998. Terplex system for delivery of DNA and oligonucleotides. Self-assembling complexes for gene delivery (ed. Kabanov AV, et al.), pp. 149-166. Wiley, New York.
25. Lim YB, Kim CH, Kim K, Kim SW, Park JS. 2000a. Development of a safe gene delivery system using biodegradable polymer, poly[α-(4-aminobutyl)-L-glycolic acid]. J Am Chem Soc 122: 6524-6525.
26. Lim YB, Han SO, Kong HU, Lee Y, Park JS, Jeong B, Kim SW. 2000b. Biodegradable polyester, poly[α-(4-aminobutyl)-L-glycolic acid], as a non-toxic gene carrier. Pharm Res 17: 811-816.
27. Midoux P, Monsigny M. 1999. Efficient gene transfer by histidylated polylysine/pDNA complexes. Bioconjug Chem 10: 406-411.
28. Midoux P, Mendes C, Legrand A, Raimond J, Mayer R, Monsigny M, Roche AC. 1993. Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells. Nucleic Acids Res 21: 871-878.
29. Ohki S, Duax J. 1986. Effects of cations and polyamines on the aggregation and fusion of phosphatidylserine membranes. Biochim Biophys Acta 861: 177-186.
30. Olins DE, Olins AL, Von Hippel PH. 1967. Model nucleoprotein complexes: Studies on the interaction of cationic homopolypeptides with DNA. J Mol Biol 24: 157-176.
31. Pack DW, Putnam D, Langer R. 2000. Design of imidazole-containing endosomolytic biopolymer for gene delivery. Biotech Bioeng 67: 217-223.
32. Perales JC, Grossmann GA, Molas M, Liu G, Ferkol T, Harpst J, Oda H, Hannson RW. 1997. Biochemical and functional characterization of DNA complexes capable of targeting genes to hepatocytes via the asialoglycoprotein receptor. J Biol Chem 272: 7398-7407.
33. Plank C, Mechtler K, Szoka FC, Wagner E. 1996. Activation of the complement system by synthetic DNA complexes: A potential barrier for intravenous gene delivery. Hum Gene Ther 7: 1437-1446.
34. Pouton CW, Lucas P, Thomas BJ, Uduchi AN, Milroy DA, Moss SH. 1998. Polycation-DNA complexes for gene delivery: A comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids. J Control Release 53: 289-299.
35. + cells. Gene Ther 6: 1774-1778.
36. Putnam D, Gentry CA, Pack DW, Langer R. 2001. Polymer based gene delivery with low cytotoxicity by a unique balance of side chain termini. Proc Natl Acad Sci 98: 1200-1205.
37. Rosenkranz AA, Yachmenev SV, Jans DA, Serebryakova NV, Murav'ev VI, Peters R, Sobolev AS. 1992. Receptor-mediated endocytosis and nuclear transport of a transfecting DNA construct. Exp Cell Res 199: 323-329.
38. Schaffer DV, Fidelman NA, Dan N, Lauffenburger DA. 2000. Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery. Biotechnol Bioeng 67: 598-606.
39. Shapiro JT, Leng M, Felsenfeld G. 1969. Deoxyribonucleic acid-polylysine complexes: Structure and nucleotide specificity. Biochemistry 8: 3119-3132.
40. Takahashi H, Matuoka S, Kato S, Ohki K, Hatta I. 1991. Electrostatic interaction of poly(L-lysine) with dipalmitoylphosphatidic acid studied by X-ray diffraction. Biochim Biophys Acta 1069: 229-234.
41. Tang MX, Szoka FC. 1997. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther 4: 823-832.
42. Toncheva V, Wolfert M, Dash P, Oupicky D, Ulbrich K, Seymour L, Schacht E. 1998. Novel vectors for gene delivery formed by self-assembly of DNA with poly(Llysine) grafted with hydrophilic polymers. Biochim Biophys Acta 1380: 354-368.
43. Tsuboi M, Matsuo K, Ts'o PO. 1996. Interaction of poly-L-lysine and nucleic acids. J Mol Biol 15: 256-267.
44. Wagner E, Cotten M, Foisner R, Birnstiel ML. 1991. Transferrin-polycation-DNA complexes: The effect of polycations on the structure of the complex and DNA delivery to cells. Proc Natl Acad Sci 88: 4255-4259.
45. Wagner E, Plank C, Zatloukai K, Cotten M, Birnstiel M. 1992. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: Toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci 89: 7934-7938.
46. Walter A, Steer CJ, Blumenthal R. 1986. Polylysine induces pH-dependent fusion of acidic phospholipid vesicles: A model for polycation-induced fusion. Biochim Biophys Acta 861: 319-330.
47. Wolfert MA, Seymour LW. 1996. Atomic force microscopic analysis of the influence of the molecular weight of poly(L)lysine on the size of polyelectrolyte complexes formed with DNA. Gene Ther 3: 269-273.
48. Wolfert M, Schacht E, Toncheva V, Ulbrich K, Nazarova O, Seymour L. 1996. Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Hum Gene Ther 7: 2123-2133.
49. Yu L, Nielson M, Han SO, Kim SW. 2001a. TerplexDNA gene carrier system targeting artery wall cells. J Control Release 72: 179-185.
50. Yu L, Suh H, Koh JJ, Kim SW. 2001b. Systemic administration of TerplexDNA system: Pharmacokinetics and gene expression. Pharm Res 18: 1277-1283.