Myocyte enhancer factor-2 and cardiac muscle gene expression during hibernation in thirteen-lined ground squirrels

Gene

Volumn 501, Issue 1, 2012, Pages 8-16

  Tessier, Shannon N ^a   Storey, Kenneth B ^a  

^a CARLETON UNIVERSITY   (Canada)

Author keywords

Cardiac muscle; Hibernation; Hypertrophy; Ictidomys tridecemlineatus; Myocyte enhancer factor 2

Indexed keywords

DESMIN; GLUCOSE TRANSPORTER 4; MESSENGER RNA; MYOCYTE ENHANCER FACTOR 2; MYOMESIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; GENE EXPRESSION; HEART MUSCLE; HIBERNATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SCIURIDAE;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HIBERNATION; MYOCARDIUM; MYOGENIC REGULATORY FACTORS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SCIURIDAE;

ANIMALIA; MAMMALIA; SPERMOPHILUS TRIDECEMLINEATUS;

EID: 84860571898     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2012.04.004     Document Type: Article

References (62)

1. Agarkiva I., Perriard J.C. The M-band: an elastic web that crosslinks thick filaments in the center of the sarcomere. Trends Cell Biol. 2005, 15:477-485.
2. Akazawa H., Komuro I. Roles of cardiac transcription factors in cardiac hypertrophy. Circ. Res. 2003, 92:1079-1088.
3. Amat R., Planavila A., Chen S.L., Iglesias R., Giralt M., Villarroya F. SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD. J. Biol. Chem. 2009, 284:21872-21880.
4. Besse F., Ephrussi A. Translational control of localized mRNAs: restricting protein synthesis in space and time. Nat. Rev. Mol. Cell Biol. 2008, 9:971-980.
5. Biggar K.K., Storey K.B. The emerging roles of microRNAs in the molecular responses of metabolic rate depression. J. Mol. Cell Biol. 2011, 3:167-175.
6. Black B.L., Olson E.N. Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu. Rev. Cell Dev. Biol. 1998, 14:167-196.
7. Bratincsák A., McMullen D., Miyake S., Tóth Z.E., Hallenbeck J.M., Palkovits M. Spatial and temporal activation of brain regions in hibernation: c-fos expression during the hibernation bout in thirteen-lined ground squirrel. J. Comp. Neurol. 2007, 505:443-458.
8. Brauch K.M., Dhruv N.D., Hanse E.A., Andrews M.T. Digital transcriptome analysis indicates adaptive mechanisms in the heart of a hibernating mammal. Physiol. Genomics 2005, 23:227-234.
9. Buchan J.R., Parker R. Eukaryotic stress granules: the ins and outs of translation. Mol. Cell 2009, 36:932-941.
10. Buck C.L., Barnes B.M. Effects of ambient temperature on metabolic rate, respiratory quotient, and torpor in an arctic hibernator. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000, 279:R255-R262.
11. Capetanaki Y., Bloch R.J., Kouloumenta A., Mavroidis M., Psarras S. Muscle intermediate filaments and their links to membranes and membranous organelles. Exp. Cell Res. 2007, 313:2063-2076.
12. Cox D.M., et al. Phosphorylation motifs regulating the stability and function of myocyte enhancer factor 2A. J. Biol. Chem. 2003, 278:15297-15303.
13. Czubryt M.P., Olson E.N. Balancing contractility and energy production: the role of myocyte enhancer factor 2 (MEF2) in cardiac hypertrophy. Recent Prog. Horm. Res. 2004, 59:105-124.
14. 2+ and proton flux dysregulation. J. Mol. Cell. Cardiol. 2010, 48:663-672.
15. Eddy S.F., Morin P., Storey K.B. Cloning and expression of PPAR-gamma and PGC-1alpha from the hibernating ground squirrel, Spermophilus tridecemlineatus. Mol. Cell. Biochem. 2005, 269:175-182.
16. Fahlman A., Storey J.M., Storey K.B. Gene up-regulation in heart during mammalian hibernation. Cryobiology 2000, 40:332-342.
17. Frerichs K.U., Hallenbeck J.M. Hibernation in ground squirrels induces state and species-specific tolerance to hypoxia and aglycemia: an in vitro study in hippocampal slices. J. Cereb. Blood Flow Metab. 1998, 18:168-175.
18. Frerichs K.U., Kennedy C., Sokoloff L., Hallenbeck J.M. Local cerebral blood flow during hibernation, a model of natural tolerance to "cerebral ischemia". J. Cereb. Blood Flow Metab. 1994, 14:193-205.
19. Frey N., Katus H.A., Olson E.N., Hill J.A. Hypertrophy of the heart: a new therapeutic target?. Circulation 2004, 109:1580-1589.
20. Gautel M. The sarcomeric cytoskeleton: who picks up the strain?. Curr. Opin. Cell Biol. 2010, 23:39-46.
21. Geiser F. Metabolic rate and body temperature reduction during hibernation and daily torpor. Annu. Rev. Physiol. 2004, 66:239-274.
22. Goldfarb L.G., Dalakas M.C. Tragedy in a heartbeat: malfunctioning desmin causes skeletal and cardiac muscle disease. J. Clin. Invest. 2009, 119:1806-1813.
23. Goldfarb L.G., et al. Missense mutations in desmin associated with familial cardiac and skeletal myopathy. Nat. Genet. 1998, 19:402-403.
24. Hornemann T., Kempa S., Himmel M., Hayess K., Fürst D.O., Wallimann T. Muscle-type creatine kinase interacts with central domains of the M-band proteins myomesin and M-protein. J. Mol. Biol. 2003, 332:877-887.
25. Ivaska J., Pallari H.M., Nevo J., Eriksson J.E. Novel functions of vimentin in cell adhesion, migration, and signaling. Exp. Cell Res. 2007, 313:2050-2062.
26. Kang J., Gocke C.B., Yu H. Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity. BMC Biochem. 2006, 7:1-14.
27. Kato Y., et al. Big mitogen-activated kinase regulates multiple members of the MEF2 protein family. J. Biol. Chem. 2000, 275:18534-18540.
28. Kuisk I.R., Li H., Tran D., Capetanaki Y. A single MEF2 site governs desmin transcription in both heart and skeletal muscle during mouse embryogenesis. Dev. Biol. 1996, 174:1-13.
29. Kuzman J.A., Thomas T.A., Vogelsang K.A., Said S., Anderson B.E., Gerdes A.M. Effects of induced hyperthyroidism in normal and cardiomyopathic hamsters. J. Appl. Physiol. 2005, 99:1428-1433.
30. Lange S., et al. Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2. J. Cell Sci. 2002, 115:4925-4936.
31. Lin Q., Schwarz J., Bucana C., Olson E.N. Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science 1997, 276:1404-1407.
32. 2+ sensitivity in rat and ground squirrel. Am. J. Physiol. 1993, 264:R104-R108.
33. Liu N., et al. An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:20844-20849.
34. 2+-dependent signaling cascade. J. Cell Biol. 2005, 170:37-47.
35. MacDonald J.A., Storey K.B. Mitogen-activated protein kinases and selected downstream targets display organ-specific responses in the hibernating ground squirrel. Int. J. Biochem. Cell Biol. 2005, 37:679-691.
36. Maeda T., Gupta M.P., Stewart A.F. TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters. Biochem. Biophys. Res. Commun. 2002, 294:791-797.
37. McMullen D.C., Hallenbeck J.M. Regulation of Akt during torpor in the hibernating ground squirrel, Ictidomys tridecemlineatus. J. Comp. Physiol. B 2010, 180:927-934.
38. Molkentin J.D., Markham B.E. Myocyte-specific enhancer-binding factor (MEF-2) regulates alpha-cardiac myosin heavy chain gene expression in vitro and in vivo. J. Biol. Chem. 1993, 268:19512-19520.
39. Morano I., Adler K., Agostini B., Hasselbach W. Expression of myosin heavy and light chains and phosphorylation of the phosphorylatable myosin light chain in the heart ventricle of the European hamster during hibernation and in summer. J. Muscle Res. Cell Motil. 1992, 13:64-70.
40. Muñoz J.P., et al. The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling. Biochem. Biophys. Res. Commun. 2009, 388:155-160.
41. Nakipova O.V., et al. The seasonal peculiarities of force-frequency relationships in active ground squirrel Spermophilus undulatus ventricle. Cryobiology 2007, 55:173-181.
42. Naya F.J., et al. Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nat. Med. 2002, 8:1303-1309.
43. Ornatsky O.I., et al. Post-translational control of the MEF2A transcriptional regulatory protein. Nucleic Acids Res. 1999, 27:2646-2654.
44. Patterson B., Fields A.V., Shannon R.P. New insights into myocardial glucose metabolism: surviving under stress. Curr. Opin. Clin. Nutr. Metab. Care 2009, 12:424-430.
45. Peng J., Raddatz K., Labeit S., Granzier H., Gotthardt M. Muscle atrophy in titin M-line deficient mice. J. Muscle Res. Cell Motil. 2006, 26:381-388.
46. Pinotsis N., Lange S., Perriard J.C., Svergun D.I., Wilmanns M. Molecular basis of the C-terminal tail-to-tail assembly of the sarcomeric filament protein myomesin. EMBO J. 2008, 27:253-264.
47. Potthoff M.J., Olson E.N. MEF2: a central regulator of diverse developmental programs. Development 2007, 134:4131-4140.
48. Riquelme C., Barthel K.K., Liu X. SUMO-1 modification of MEF2A regulates its transcriptional activity. J. Cell. Mol. Med. 2006, 10:132-144.
49. Steiner F., Weber K., Fürst D.O. M band proteins myomesin and skelemin are encoded by the same gene: analysis of its organization and expression. Genomics 1999, 56:78-89.
50. Storey K.B. Out cold: biochemical regulation of mammalian hibernation - a mini-review. Gerontology 2010, 56:220-230.
51. Storey K.B., Storey J.M. Metabolic rate depression in animals: transcriptional and translational controls. Biol. Rev. 2004, 79:207-233.
52. Storey K.B., Storey J.M. Metabolic rate depression: the biochemistry of mammalian hibernation. Clin. Chem. 2010, 52:77-108.
53. Streicher J.M., Ren S., Herschman H., Wang Y. MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart. Circ. Res. 2010, 106:1434-1443.
54. Taegtmeyer H., Sen S., Vela D. Return to the fetal gene program: a suggested metabolic link to gene expression in the heart. Ann. N.Y. Acad. Sci. 2010, 1188:191-198.
55. Tessier S.N., Storey K.B. Expression of myocyte enhancer factor-2 and downstream genes in ground squirrel skeletal muscle during hibernation. Mol. Cell. Biochem. 2010, 344:151-162.
56. Thai M.V., Guruswamy S., Cao K.T., Pessin J.E., Olson A.L. Myocyte enhancer factor 2 (MEF2)-binding site is required for GLUT4 gene expression in transgenic mice. Regulation of MEF2 DNA binding activity in insulin-deficient diabetes. J. Biol. Chem. 1998, 273:14285-14292.
57. Wang L.C.H., Lee T.F. Torpor and hibernation in mammals: metabolic, physiological, and biochemical adaptations. Handbook of Physiology: Environmental Physiology 1996, 507-532. Oxford University Press, New York. M.J. Fregley, C.M. Blatteis (Eds.).
58. Wang S.Q., Lakatta E.G., Cheng H., Zhou Z.Q. Adaptive mechanisms of intracellular calcium homeostasis in mammalian hibernators. J. Exp. Biol. 2002, 205:2957-2962.
59. Wei J.Q., et al. Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300. Circulation 2008, 118:934-946.
60. Wickler S.J., Hoyt D.F., van Breukelen F. Disuse atrophy in the hibernating golden-mantled ground squirrel, Spermophilus lateralis. Am. J. Physiol. 1991, 261:R1214-R1217.
61. Yang S.H., Galanis A., Sharrocks A.D. Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors. Mol. Cell. Biol. 1999, 19:4028-4038.
62. Yoon S.C., et al. Region-specific phosphorylation of ERK5-MEF2C in the rat frontal cortex and hippocampus after electroconvulsive shock. Prog. Neuropsychopharmacol. Biol. Psychiatry 2005, 29:749-753.