-
1
-
-
78049425657
-
A novel statistic for genome-wide interaction analysis
-
doi:10.1371/journal.pgen.1001131
-
Wu X, Dong H, Luo L, Zhu Y, Peng G, et al. (2010) A novel statistic for genome-wide interaction analysis. PLoS Genet 6: e1001131 doi:10.1371/journal.pgen.1001131.
-
(2010)
PLoS Genet
, vol.6
-
-
Wu, X.1
Dong, H.2
Luo, L.3
Zhu, Y.4
Peng, G.5
-
2
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
WTCCC
-
WTCCC (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
3
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316: 889-894.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
-
4
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
Todd J, Walker N, Cooper J, Smyth D, Downes K, et al. (2007) Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 39: 857-864.
-
(2007)
Nat Genet
, vol.39
, pp. 857-864
-
-
Todd, J.1
Walker, N.2
Cooper, J.3
Smyth, D.4
Downes, K.5
-
5
-
-
42349106044
-
Meta-analysis of genomewide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, et al. (2008) Meta-analysis of genomewide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 40: 638-645.
-
(2008)
Nat Genet
, vol.40
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
Marchini, J.L.5
-
6
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, et al. (2008) Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 40: 955-962.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
-
7
-
-
79953208931
-
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis
-
Mells GF, Floyd JA, Morley KI, Cordell HJ, Franklin CS, et al. (2011) Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. Nat Genet 43: 329-332.
-
(2011)
Nat Genet
, vol.43
, pp. 329-332
-
-
Mells, G.F.1
Floyd, J.A.2
Morley, K.I.3
Cordell, H.J.4
Franklin, C.S.5
-
8
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, et al. (2009) Finding the missing heritability of complex diseases. Nature 461: 747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
-
9
-
-
77954140531
-
Common SNPs explain a large proportion of the heritability for human height
-
Yang J, Benyamin B, McEvoy BP, Gordon S, Henders AK, et al. (2010) Common SNPs explain a large proportion of the heritability for human height. Nat Genet 42: 565-569.
-
(2010)
Nat Genet
, vol.42
, pp. 565-569
-
-
Yang, J.1
Benyamin, B.2
McEvoy, B.P.3
Gordon, S.4
Henders, A.K.5
-
10
-
-
79957588287
-
Genome partitioning of genetic variation for complex traits using common SNPs
-
Yang J, Manolio TA, Pasquale LR, Boerwinkle E, Caporaso N, et al. (2011) Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet 43: 519-525.
-
(2011)
Nat Genet
, vol.43
, pp. 519-525
-
-
Yang, J.1
Manolio, T.A.2
Pasquale, L.R.3
Boerwinkle, E.4
Caporaso, N.5
-
11
-
-
0019867064
-
Biological models and statistical interactions: an example from multistage carcinogenesis
-
Siemiatycki J, Thomas DC, (1981) Biological models and statistical interactions: an example from multistage carcinogenesis. International Journal of Epidemiology 10: 383-387.
-
(1981)
International Journal of Epidemiology
, vol.10
, pp. 383-387
-
-
Siemiatycki, J.1
Thomas, D.C.2
-
12
-
-
0025959790
-
Effect modification and the limits of biological inference from epidemiologic data
-
Thompson WD, (1991) Effect modification and the limits of biological inference from epidemiologic data. Journal of Clinical Epidemiology 44: 221-232.
-
(1991)
Journal of Clinical Epidemiology
, vol.44
, pp. 221-232
-
-
Thompson, W.D.1
-
13
-
-
0031827525
-
The language of gene interaction
-
Phillips PC, (1998) The language of gene interaction. Genetics 149: 1167-1171.
-
(1998)
Genetics
, vol.149
, pp. 1167-1171
-
-
Phillips, P.C.1
-
14
-
-
0036797562
-
Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans
-
Cordell HJ, (2002) Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans. Hum Molec Genet 11: 2463-2468.
-
(2002)
Hum Molec Genet
, vol.11
, pp. 2463-2468
-
-
Cordell, H.J.1
-
15
-
-
33646059148
-
Variance component analysis of polymorphic metabolic systems
-
McClay JL, van den Oord EJ, (2006) Variance component analysis of polymorphic metabolic systems. J Theor Biol 240: 149-159.
-
(2006)
J Theor Biol
, vol.240
, pp. 149-159
-
-
McClay, J.L.1
van den Oord, E.J.2
-
16
-
-
54149088214
-
Epistasis-the essential role of gene interactions in the structure and evolution of genetic systems
-
Phillips PC, (2008) Epistasis-the essential role of gene interactions in the structure and evolution of genetic systems. Nat Rev Genet 9: 855-867.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 855-867
-
-
Phillips, P.C.1
-
17
-
-
67349166946
-
Detecting gene-gene interactions that underlie human diseases
-
Cordell HJ, (2009) Detecting gene-gene interactions that underlie human diseases. Nat Rev Genet 10: 392-404.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 392-404
-
-
Cordell, H.J.1
-
18
-
-
68249108329
-
Prediction and interaction in complex disease genetics: experience in type 1 diabetes
-
doi:10.1371/journal.pgen.1000540
-
Clayton DG, (2009) Prediction and interaction in complex disease genetics: experience in type 1 diabetes. PLoS Genet 5: e1000540 doi:10.1371/journal.pgen.1000540.
-
(2009)
PLoS Genet
, vol.5
-
-
Clayton, D.G.1
-
19
-
-
78649794378
-
The meaning of interaction
-
Wang X, Elston R, Zhu X, (2010) The meaning of interaction. Hum Hered 70: 269-277.
-
(2010)
Hum Hered
, vol.70
, pp. 269-277
-
-
Wang, X.1
Elston, R.2
Zhu, X.3
-
20
-
-
33847059098
-
Exploiting gene-environment interaction to detect genetic associations
-
Kraft P, Yen YC, Stram DO, Morrison J, Gauderman WJ, (2007) Exploiting gene-environment interaction to detect genetic associations. Hum Hered 63: 111-119.
-
(2007)
Hum Hered
, vol.63
, pp. 111-119
-
-
Kraft, P.1
Yen, Y.C.2
Stram, D.O.3
Morrison, J.4
Gauderman, W.J.5
-
21
-
-
0036499241
-
Sample size requirements for association studies of gene-gene interaction
-
Gauderman WJ, (2002) Sample size requirements for association studies of gene-gene interaction. Am J Epidemiol 155: 478-484.
-
(2002)
Am J Epidemiol
, vol.155
, pp. 478-484
-
-
Gauderman, W.J.1
-
22
-
-
38049026746
-
Detecting association using epistatic information
-
Chapman J, Clayton D, (2007) Detecting association using epistatic information. Genet Epidemiol 31: 894-909.
-
(2007)
Genet Epidemiol
, vol.31
, pp. 894-909
-
-
Chapman, J.1
Clayton, D.2
-
23
-
-
0028089404
-
Non-hierarchical logistic models and case-only designs for assessing susceptibility in population-based case-control studies
-
Piegorsch WW, Weinberg CR, Taylor JA, (1994) Non-hierarchical logistic models and case-only designs for assessing susceptibility in population-based case-control studies. Statistics in Medicine 13: 153-162.
-
(1994)
Statistics in Medicine
, vol.13
, pp. 153-162
-
-
Piegorsch, W.W.1
Weinberg, C.R.2
Taylor, J.A.3
-
24
-
-
0032915780
-
Case-only design to measure gene-gene interaction
-
Yang Q, Khoury MJ, Sun F, Flanders WD, (1999) Case-only design to measure gene-gene interaction. Epidemiology 10: 167-170.
-
(1999)
Epidemiology
, vol.10
, pp. 167-170
-
-
Yang, Q.1
Khoury, M.J.2
Sun, F.3
Flanders, W.D.4
-
25
-
-
0034255484
-
Choosing a retrospective design to assess joint genetic and environmental contributions to risk
-
Weinberg CR, Umbach DM, (2000) Choosing a retrospective design to assess joint genetic and environmental contributions to risk. Am J Epidemiol 152: 197-203.
-
(2000)
Am J Epidemiol
, vol.152
, pp. 197-203
-
-
Weinberg, C.R.1
Umbach, D.M.2
-
26
-
-
77649235526
-
Using principal components of genetic variation for robust and powerful detection of gene-gene interactions in case-control and case-only studies
-
Bhattacharjee S, Wang Z, Ciampa J, Kraft P, Chanock S, et al. (2010) Using principal components of genetic variation for robust and powerful detection of gene-gene interactions in case-control and case-only studies. Am J Hum Genet 86: 331-342.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 331-342
-
-
Bhattacharjee, S.1
Wang, Z.2
Ciampa, J.3
Kraft, P.4
Chanock, S.5
-
27
-
-
33646028514
-
Contrasting linkage-disequilibrium patterns between cases and controls as a novel association-mapping method
-
Zaykin DV, Meng Z, Ehm MG, (2006) Contrasting linkage-disequilibrium patterns between cases and controls as a novel association-mapping method. Am J Hum Genet 78: 737-746.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 737-746
-
-
Zaykin, D.V.1
Meng, Z.2
Ehm, M.G.3
-
28
-
-
0031466983
-
From genotypes to genes: doubling the sample size
-
Sasieni P, (1997) From genotypes to genes: doubling the sample size. Biometrics 53: 1253-1261.
-
(1997)
Biometrics
, vol.53
, pp. 1253-1261
-
-
Sasieni, P.1
-
29
-
-
0016560436
-
Sample sizes required to detect linkage disequilibrium between two or three loci
-
Brown A, (1975) Sample sizes required to detect linkage disequilibrium between two or three loci. Theoretical Population Biology 8: 184-201.
-
(1975)
Theoretical Population Biology
, vol.8
, pp. 184-201
-
-
Brown, A.1
-
30
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
-
31
-
-
0023796209
-
On measures of gametic disequilibrium
-
Lewontin R, (1998) On measures of gametic disequilibrium. Genetics 120: 849-852.
-
(1998)
Genetics
, vol.120
, pp. 849-852
-
-
Lewontin, R.1
-
32
-
-
33748804424
-
A tutorial on statistical methods for population association studies
-
Balding DJ, (2006) A tutorial on statistical methods for population association studies. Nat Rev Genet 7: 781-791.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 781-791
-
-
Balding, D.J.1
-
33
-
-
57449115418
-
A genotype based approach to assessing the association between single nucleotide polymorphisms
-
Wellek S, Ziegler A, (2009) A genotype based approach to assessing the association between single nucleotide polymorphisms. Hum Hered 67: 128-139.
-
(2009)
Hum Hered
, vol.67
, pp. 128-139
-
-
Wellek, S.1
Ziegler, A.2
-
34
-
-
79952740772
-
EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units
-
Kam-Thong T, Czamara D, Tsuda K, Borgwardt K, Lewis CM, et al. (2011) EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units. Eur J Hum Genet 19: 465-471.
-
(2011)
Eur J Hum Genet
, vol.19
, pp. 465-471
-
-
Kam-Thong, T.1
Czamara, D.2
Tsuda, K.3
Borgwardt, K.4
Lewis, C.M.5
-
35
-
-
84856478855
-
A linear complexity phasing method for thousands of genomes
-
doi:10.1038/nmeth.1785
-
Delaneau O, Marchini J, Zagury JF, (2011) A linear complexity phasing method for thousands of genomes. Nature Methods doi:10.1038/nmeth.1785.
-
(2011)
Nature Methods
-
-
Delaneau, O.1
Marchini, J.2
Zagury, J.F.3
-
36
-
-
49749089301
-
Exploiting gene-environment independence for analysis of casecontrol studies: an empirical Bayes-type shrinkage estimator to trade-off between bias and efficiency
-
Mukherjee B, Chatterjee N, (2008) Exploiting gene-environment independence for analysis of casecontrol studies: an empirical Bayes-type shrinkage estimator to trade-off between bias and efficiency. Biometrics 64: 685-94.
-
(2008)
Biometrics
, vol.64
, pp. 685-694
-
-
Mukherjee, B.1
Chatterjee, N.2
-
37
-
-
12744255341
-
Semiparametric maximum likelihood estimation exploiting geneenvironment independence in case-control studies
-
Chatterjee N, Carroll RJ, (2005) Semiparametric maximum likelihood estimation exploiting geneenvironment independence in case-control studies. Biometrika 92: 399-418.
-
(2005)
Biometrika
, vol.92
, pp. 399-418
-
-
Chatterjee, N.1
Carroll, R.J.2
-
38
-
-
79955506078
-
Large-scale exploration of gene-gene interactions in prostate cancer using a multistage genome-wide association study
-
Ciampa J, Yeager M, Amundadottir L, Jacobs K, Kraft P, et al. (2011) Large-scale exploration of gene-gene interactions in prostate cancer using a multistage genome-wide association study. Cancer Res 71: 3287-3295.
-
(2011)
Cancer Res
, vol.71
, pp. 3287-3295
-
-
Ciampa, J.1
Yeager, M.2
Amundadottir, L.3
Jacobs, K.4
Kraft, P.5
|