메뉴 건너뛰기




Volumn 137, Issue 4, 2012, Pages 627-632

Rapid detection of Klebsiella pneumoniae carbapenemase genes in enterobacteriaceae directly from blood culture bottles by real-time PCR

Author keywords

Bloodstream infection; Carbapenemase; Enterobacteriaceae; Klebsiella pneumoniae; Real time polymerase chain reaction

Indexed keywords

CARBAPENEMASE; ERTAPENEM; IMIPENEM; MEROPENEM;

EID: 84860552880     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCP9SNHJG2QGLWU     Document Type: Article
Times cited : (26)

References (37)
  • 1
    • 62749195559 scopus 로고    scopus 로고
    • The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria
    • Nordmann P, Cuzon G, Naas T. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis. 2009;9:228-236.
    • (2009) Lancet Infect Dis , vol.9 , pp. 228-236
    • Nordmann, P.1    Cuzon, G.2    Naas, T.3
  • 3
    • 44449165917 scopus 로고    scopus 로고
    • Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a chinese hospital
    • DOI 10.1128/AAC.01539-07
    • Cai JC, Zhou HW, Zhang R, et al.Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. Antimicrob Agents Chemother. 2008;52:2014-2018. (Pubitemid 351758537)
    • (2008) Antimicrobial Agents and Chemotherapy , vol.52 , Issue.6 , pp. 2014-2018
    • Jia, C.C.1    Hong, W.Z.2    Zhang, R.3    Chen, G.-X.4
  • 4
    • 25844520534 scopus 로고    scopus 로고
    • Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC in a Klebsiella pneumoniae isolate from France [3]
    • DOI 10.1128/AAC.49.10.4423-4424.2005
    • Naas T, Nordmann P, Vedel G, et al.Plasmid-mediated carbapenem- hydrolyzing beta-lactamase KPC in a Klebsiella pneumoniae isolate from France [letter]. Antimicrob Agents Chemother. 2005;49:4423-4424. (Pubitemid 41401006)
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , Issue.10 , pp. 4423-4424
    • Naas, T.1    Nordmann, P.2    Vedel, G.3    Poyart, C.4
  • 6
    • 77951045230 scopus 로고    scopus 로고
    • Outbreak of carbapenem-resistant Klebsiella pneumoniae in Puerto Rico associated with a novel carbapenemase variant
    • Gregory CJ, Llata E, Stine N, et al.Outbreak of carbapenem-resistant Klebsiella pneumoniae in Puerto Rico associated with a novel carbapenemase variant. Infect Control Hosp Epidemiol. 2010;31:476-484.
    • (2010) Infect Control Hosp Epidemiol , vol.31 , pp. 476-484
    • Gregory, C.J.1    Llata, E.2    Stine, N.3
  • 7
    • 84860892886 scopus 로고    scopus 로고
    • Escherichia coli strain P3000136 beta lactamase KPC-9 (blaKPC) gene, partial cds
    • (accession No. FJ624872). Available at Accessed August 8, 2010
    • Hidalgo-Grass C, Benenson S, Temper V, et al.Escherichia coli strain P3000136 beta lactamase KPC-9 (blaKPC) gene, partial cds. In: GenBank (accession No. FJ624872). 2009. Available at http://www.ncbi.nlm.nih.gov/nuccore/FJ624872. 1. Accessed August 8, 2010.
    • (2009) GenBank
    • Hidalgo-Grass, C.1    Benenson, S.2    Temper, V.3
  • 8
    • 84860892885 scopus 로고    scopus 로고
    • Klebsiella pneumoniae plasmid pKp10-26 beta lactamase KPC-11 (blaKPC) gene, blaKPC-11 allele, complete cds
    • (accession No. HM066995). Available at Accessed August 8, 2010
    • Lascols C, Hackel M, Hawser S, et al.Klebsiella pneumoniae plasmid pKp10-26 beta lactamase KPC-11 (blaKPC) gene, blaKPC-11 allele, complete cds. In: GenBank (accession No. HM066995). 2010. Available at http://www.ncbi.nlm. nih.gov/nuccore/HM066995.1. Accessed August 8, 2010.
    • (2010) GenBank
    • Lascols, C.1    Hackel, M.2    Hawser, S.3
  • 9
    • 77954734451 scopus 로고    scopus 로고
    • Carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae across a hospital system: Impact of post-acute care facilities on dissemination
    • Perez F, Endimiani A, Ray AJ, et al.Carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae across a hospital system: impact of post-acute care facilities on dissemination. J Antimicrob Chemother. 2010;65:1807-1818.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 1807-1818
    • Perez, F.1    Endimiani, A.2    Ray, A.J.3
  • 11
    • 84860893528 scopus 로고    scopus 로고
    • Klebsiella pneumoniae strain Kp-421 beta-lactamase KPC-6 (blaKPC-6) gene, complete cds
    • (accession No. EU555534). Available at Accessed November 1, 2010
    • Robledo IE, Vazquez GJ, Aquino EE, et al.Klebsiella pneumoniae strain Kp-421 beta-lactamase KPC-6 (blaKPC-6) gene, complete cds. In: GenBank (accession No. EU555534). 2008. Available at http://www.ncbi.nlm.nih.gov/ nuccore/172054654. Accessed November 1, 2010.
    • (2008) GenBank
    • Robledo, I.E.1    Vazquez, G.J.2    Aquino, E.E.3
  • 13
    • 59749106051 scopus 로고    scopus 로고
    • Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4
    • Wolter DJ, Kurpiel PM, Woodford N, et al.Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4. Antimicrob Agents Chemother. 2009;53:557-562.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 557-562
    • Wolter, D.J.1    Kurpiel, P.M.2    Woodford, N.3
  • 14
    • 84860907819 scopus 로고    scopus 로고
    • Enterobacter sp E624 carbapenem-hydrolyzing beta-lactamase KPC-4 (blaKPC-4) gene, partial cds
    • (accession No. AY700571). Available at Accessed August 4, 2010
    • Woodford N, Palepou MF, Hope R, et al.Enterobacter sp E624 carbapenem-hydrolyzing beta-lactamase KPC-4 (blaKPC-4) gene, partial cds. In: GenBank (accession No. AY700571). 2004. Available at http://www.ncbi.nlm.nih. gov/nuccore/AY700571.1. Accessed August 4, 2010.
    • (2004) GenBank
    • Woodford, N.1    Palepou, M.F.2    Hope, R.3
  • 17
    • 38049063945 scopus 로고    scopus 로고
    • Identification of carbapenem-resistant Klebsiella pneumoniae harboring KPC enzymes in New Jersey
    • Chiang T, Mariano N, Urban C, et al.Identification of carbapenem-resistant Klebsiella pneumoniae harboring KPC enzymes in New Jersey. Microb Drug Resist. 2007;13:235-239.
    • (2007) Microb Drug Resist , vol.13 , pp. 235-239
    • Chiang, T.1    Mariano, N.2    Urban, C.3
  • 18
    • 33845223883 scopus 로고    scopus 로고
    • Emergence of serine carbapenemases (KPC and SME) among clinical strains of Enterobacteriaceae isolated in the United States Medical Centers: Report from the MYSTIC Program (1999-2005)
    • DOI 10.1016/j.diagmicrobio.2006.07.004, PII S0732889306002513
    • Deshpande LM, Rhomberg PR, Sader HS, et al.Emergence of serine carbapenemases (KPC and SME) among clinical strains of Enterobacteriaceae isolated in the United States medical centers: report from the MYSTIC Program (1999-2005). Diagn Microbiol Infect Dis. 2006;56:367-372. (Pubitemid 44854361)
    • (2006) Diagnostic Microbiology and Infectious Disease , vol.56 , Issue.4 , pp. 367-372
    • Deshpande, L.M.1    Rhomberg, P.R.2    Sader, H.S.3    Jones, R.N.4
  • 20
    • 34447580065 scopus 로고    scopus 로고
    • Evolution of antimicrobial resistance among Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae in Brooklyn, NY
    • DOI 10.1093/jac/dkm129
    • Landman D, Bratu S, Kochar S, et al.Evolution of antimicrobial resistance among Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae in Brooklyn, NY. J Antimicrob Chemother. 2007;60:78-82. (Pubitemid 47073279)
    • (2007) Journal of Antimicrobial Chemotherapy , vol.60 , Issue.1 , pp. 78-82
    • Landman, D.1    Bratu, S.2    Kochar, S.3    Panwar, M.4    Trehan, M.5    Doymaz, M.6    Quale, J.7
  • 21
    • 45149091874 scopus 로고    scopus 로고
    • Detection of the Klebsiella pneumoniae carbapenemase type 2 carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K. oxytoca carrying a common plasmid
    • DOI 10.1128/JCM.02038-07
    • Rasheed JK, Biddle JW, Anderson KF, et al.Detection of the Klebsiella pneumoniae carbapenemase type 2 carbapenem-hydrolyzing enzyme in clinical isolates of Citrobacter freundii and K oxytoca carrying a common plasmid. J Clin Microbiol. 2008;46:2066-2069. (Pubitemid 351831844)
    • (2008) Journal of Clinical Microbiology , vol.46 , Issue.6 , pp. 2066-2069
    • Rasheed, J.K.1    Biddle, J.W.2    Anderson, K.F.3    Washer, L.4    Chenoweth, C.5    Perrin, J.6    Newton, D.W.7    Patel, J.B.8
  • 22
    • 53649096227 scopus 로고    scopus 로고
    • Detection of KPC-2 in a clinical isolate of Proteus mirabilis and first reported description of carbapenemase resistance caused by a KPC beta-lactamase in P mirabilis
    • Tibbetts R, Frye JG, Marschall J, et al.Detection of KPC-2 in a clinical isolate of Proteus mirabilis and first reported description of carbapenemase resistance caused by a KPC beta-lactamase in P mirabilis . J Clin Microbiol. 2008;46:3080-3083.
    • (2008) J Clin Microbiol , vol.46 , pp. 3080-3083
    • Tibbetts, R.1    Frye, J.G.2    Marschall, J.3
  • 23
    • 22144436291 scopus 로고    scopus 로고
    • Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City: A new threat to our antibiotic armamentarium
    • DOI 10.1001/archinte.165.12.1430
    • Bratu S, Landman D, Haag R, et al.Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City: a new threat to our antibiotic armamentarium. Arch Intern Med. 2005;165:1430-1435. (Pubitemid 40973427)
    • (2005) Archives of Internal Medicine , vol.165 , Issue.12 , pp. 1430-1435
    • Bratu, S.1    Landman, D.2    Haag, R.3    Recco, R.4    Eramo, A.5    Alam, M.6    Quale, J.7
  • 24
    • 34547422759 scopus 로고    scopus 로고
    • Carbapenemases: The versatile beta-lactamases
    • table of contents
    • Queenan AM, Bush K. Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev. 2007;20:440-458, table of contents.
    • (2007) Clin Microbiol Rev , vol.20 , pp. 440-458
    • Queenan, A.M.1    Bush, K.2
  • 25
    • 0035262126 scopus 로고    scopus 로고
    • Modified Hodge and EDTA-disk synergy tests to screen metallo-beta- lactamase-producing strains of Pseudomonas and Acinetobacter species
    • DOI 10.1046/j.1469-0691.2001.00204.x
    • Lee K, Chong Y, Shin HB, et al.Modified Hodge and EDTA-disk synergy tests to screen metallo-beta-lactamase-producing strains of Pseudomonas and Acinetobacter species. Clin Microbiol Infect. 2001;7:88-91. (Pubitemid 34960278)
    • (2001) Clinical Microbiology and Infection , vol.7 , Issue.2 , pp. 88-91
    • Lee, K.1    Chong, Y.2    Shin, H.B.3    Kim, Y.A.4    Yong, D.5    Yum, J.H.6
  • 26
    • 60849111684 scopus 로고    scopus 로고
    • Development and evaluation of a real-time PCR assay for detection of Klebsiella pneumoniae carbapenemase genes
    • Cole JM, Schuetz AN, Hill CE, et al.Development and evaluation of a real-time PCR assay for detection of Klebsiella pneumoniae carbapenemase genes. J Clin Microbiol. 2009;47:322-326.
    • (2009) J Clin Microbiol , vol.47 , pp. 322-326
    • Cole, J.M.1    Schuetz, A.N.2    Hill, C.E.3
  • 27
    • 53649093240 scopus 로고    scopus 로고
    • Rapid detection of blaKPC carbapenemase genes by real-time PCR
    • Hindiyeh M, Smollen G, Grossman Z, et al.Rapid detection of blaKPC carbapenemase genes by real-time PCR. J Clin Microbiol. 2008;46:2879-2883.
    • (2008) J Clin Microbiol , vol.46 , pp. 2879-2883
    • Hindiyeh, M.1    Smollen, G.2    Grossman, Z.3
  • 28
    • 70349641149 scopus 로고    scopus 로고
    • Evaluation of PCR-based testing for surveillance of KPC-producing carbapenem-resistant members of the Enterobacteriaceae family
    • Schechner V, Straus-Robinson K, Schwartz D, et al.Evaluation of PCR-based testing for surveillance of KPC-producing carbapenem-resistant members of the Enterobacteriaceae family. J Clin Microbiol. 2009;47:3261-3265.
    • (2009) J Clin Microbiol , vol.47 , pp. 3261-3265
    • Schechner, V.1    Straus-Robinson, K.2    Schwartz, D.3
  • 30
    • 54949148412 scopus 로고    scopus 로고
    • NHSN annual update: Antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007
    • Hidron AI, Edwards JR, Patel J, et al.NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007. Infect Control Hosp Epidemiol. 2008;29:996-1011.
    • (2008) Infect Control Hosp Epidemiol , vol.29 , pp. 996-1011
    • Hidron, A.I.1    Edwards, J.R.2    Patel, J.3
  • 31
    • 1542723489 scopus 로고    scopus 로고
    • Rapid Detection of Klebsiella pneumoniae from Blood Culture Bottles by Real-Time PCR
    • DOI 10.1128/JCM.42.3.1337-1340.2004
    • Kurupati P, Chow C, Kumarasinghe G, et al.Rapid detection of Klebsiella pneumoniae from blood culture bottles by real-time PCR. J Clin Microbiol. 2004;42:1337-1340. (Pubitemid 38332884)
    • (2004) Journal of Clinical Microbiology , vol.42 , Issue.3 , pp. 1337-1340
    • Kurupati, P.1    Chow, C.2    Kumarasinghe, G.3    Poh, C.L.4
  • 32
    • 79959833446 scopus 로고    scopus 로고
    • Rapid detection of blaKPC carbapenemase genes by internally controlled real-time PCR assay using Bactec blood culture bottles
    • Hindiyeh M, Smollan G, Grossman Z, et al.Rapid detection of blaKPC carbapenemase genes by internally controlled real-time PCR assay using Bactec blood culture bottles. J Clin Microbiol. 2011;49:2480-2484.
    • (2011) J Clin Microbiol , vol.49 , pp. 2480-2484
    • Hindiyeh, M.1    Smollan, G.2    Grossman, Z.3
  • 33
    • 0015386608 scopus 로고
    • Reliability of the Kirby-Bauer disc diffusion method for detecting methicillin-resistant strains of Staphylococcus aureus
    • Drew WL, Barry AL, O'Toole R, et al.Reliability of the Kirby-Bauer disc diffusion method for detecting methicillin-resistant strains of Staphylococcus aureus . Appl Microbiol. 1972;24:240-247.
    • (1972) Appl Microbiol , vol.24 , pp. 240-247
    • Drew, W.L.1    Barry, A.L.2    O'Toole, R.3
  • 34
    • 65349084964 scopus 로고    scopus 로고
    • Clinical and Laboratory Standards Institute. Wayne, PA: Clinical Laboratory Standards Institute; CLSI/NCCLS document M100-S19
    • Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; 19th informational supplement . 2009. Wayne, PA: Clinical Laboratory Standards Institute; CLSI/NCCLS document M100-S19.
    • (2009) Performance Standards for Antimicrobial Susceptibility Testing; 19th Informational Supplement
  • 35
    • 84860907817 scopus 로고    scopus 로고
    • Accessed June 5, 2011
    • National Center for Biotechnology Information. http://blast.ncbi.nlm.nih. gov/Blast.cgi. Accessed June 5, 2011.
  • 36
    • 0031026934 scopus 로고    scopus 로고
    • Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the loss of an outer membrane protein
    • Bradford PA, Urban C, Mariano N, et al.Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the loss of an outer membrane protein. Antimicrob Agents Chemother. 1997;41:563-569. (Pubitemid 27098404)
    • (1997) Antimicrobial Agents and Chemotherapy , vol.41 , Issue.3 , pp. 563-569
    • Bradford, P.A.1    Urban, C.2    Mariano, N.3    Projan, S.J.4    Rahal, J.J.5    Bush, K.6
  • 37
    • 77952711660 scopus 로고    scopus 로고
    • Transfer of carbapenem-resistant plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in patient
    • Goren MG, Carmeli Y, Schwaber MJ, et al.Transfer of carbapenem-resistant plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in patient. Emerg Infect Dis. 2010;16:1014-1017.
    • (2010) Emerg Infect Dis , vol.16 , pp. 1014-1017
    • Goren, M.G.1    Carmeli, Y.2    Schwaber, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.