Haploidization in Saccharomyces cerevisiae induced by a Deficiency in homologous recombination

Genetics

Volumn 191, Issue 1, 2012, Pages 279-284

  Song, Wei ^a   Petes, Thomas D ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

CHROMOSOME LOSS; COMPARATIVE GENOMIC HYBRIDIZATION; FUNGAL STRAIN; FUNGUS SPORE; GENE; GENE MUTATION; HAPLOIDY; HOMOLOGOUS RECOMBINATION; LIFE CYCLE; NONHUMAN; NOTE; PRIORITY JOURNAL; RAD52 GENE; SACCHAROMYCES CEREVISIAE; SINGLE NUCLEOTIDE POLYMORPHISM;

CHROMOSOMES, FUNGAL; GENE DELETION; HAPLOIDY; HOMOLOGOUS RECOMBINATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; RAD52 DNA REPAIR AND RECOMBINATION PROTEIN; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 84860551443     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.111.138180     Document Type: Note

References (21)

1. Alabrudzinska, M., M. Skoneczny, and A. Skoneczna, 2011 Diploid-specific genome stability genes of S. cerevisiae genomic screen reveals haploidization as an escape from persisting DNA rearrangement stress. PLoS ONE 6: e21124.
2. Andaluz, E., A. Bellido, J. Gomez-Raja, A. Selmecki, K. Bouchonville et al., 2011 Rad52 function prevents chromosome loss and truncation in Candida albicans. Mol. Microbiol. 79: 1462-1482.
3. Casper, A. M., P. A. Mieczkowski, M. Gawel, and T. D. Petes, 2008 Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae. PLoS Genet. 4: e1000105.
4. Forche, A., K. Alby, D. Schaefer, A. D. Johnson, J. Berman et al., 2008 The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains. PLoS Biol. 6: 1-14.
5. Gerstein, A. C., H.-J. Chun, A. Grant, and S. P. Otto, 2006 Genomic convergence toward diploidy in Saccharomyces cerevisiae. PLoS Genet. 2: e145.
6. Gerstein, A. C., L. A. Cleathero, M. A. Mandegar, and S. P. Otto, 2011 Haploids adapt faster than diploids across a range of environments. J. Evol. Biol. 24: 531-540.
7. Goldstein, A. L., and J. H. McCusker, 1999 Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15: 1541-1553.
8. Gresham, D., M. J. Dunham, and D. Botstein, 2008 Comparing whole genomes using DNA microarrays. Nat. Rev. Genet. 9: 291-302.
9. Klein, H. L., 2001 Spontaneous chromosome loss in Saccharomyces cerevisiae is suppressed by DNA damage checkpoint functions. Genetics 159: 1501-1509.
10. Krogh, B. O., and L. S. Symington, 2004 Recombination proteins in yeast. Annu. Rev. Genet. 38: 233-271.
11. Lemoine, F. J., N. P. Degtyareva, K. Lobachev, and T. D. Petes, 2005 Chromosomal translocations in yeast induced by low levels of DNA polymerase: a model for chromosome fragile sites. Cell 120: 587-598.
12. Lisby, M., R. Rothstein, and U. H. Mortensen, 2001 Rad52 forms DNA repair and recombination centers during S phase. Proc. Natl. Acad. Sci. USA 98: 8276-8282.
13. McCulley, J. L., and T. D. Petes, 2010 Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms. Proc. Natl. Acad. Sci. USA 107: 11465-11470.
14. Mortimer, R. K., R. Contopoulou, and D. Schild, 1981 Mitotic chromosome loss in a radiation-sensitive strain of the yeast Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 78: 5778-5782.
15. Pontecorvo, G., 1956 The parasexual cycle in fungi. Ann. Rev. Micro. 10: 393-400.
16. Shrivastav, M., L. P. De Haro, and J. A. Nickoloff, 2008 Regulation of DNA double-strand break repair pathway choice. Cell Res. 18: 134-147.
17. St. Charles, J., M. L. Hamilton, and T. D. Petes, 2010 Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae. Genetics 186: 537-550.
18. St. Charles, J., E. Hazkani-Covo, Y. Yin, S. L. Andersen, F. S. Dietrich et al., 2012 High-resolution genome-wide analysis of irradiated (UV and gamma rays) diploid yeast cells reveals a high frequency of genomic loss of heterozygosity (LOH) events. Genetics 190: 1267-1284.
19. Torres, E. M., T. Sokolsky, C. M. Tucker, L. Y. Chan, M. Boselli et al., 2007 Effects of aneuploidy on cellular physiology and cell division in haploid yeast. Science 317: 916-924.
20. Wei, W., J. H. McCusker, R. W. Hyman, T. Jones, Y. Ning et al., 2007 Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM786. Proc. Natl. Acad. Sci. USA 194: 12825-12830.
21. Yoshida, J., K. Umezu, and H. Maki, 2003 Positive and negative roles of homologous recombination in the maintenance of genome stability in Saccharomyces cerevisiae. Genetics 164: 31-46. Communicating editor: J. A. Nickoloff