Desmin as a marker of proteinuria in early stages of membranous nephropathy in elderly patients

Clinical Nephrology

Volumn 68, Issue 2, 2007, Pages 73-80

  Maruyama, M ^a   Sugiyama, Hitoshi ^a   Sada, K ^a   Kobayashi, M ^a   Maeshima, Y ^a   Yamasaki, Y ^b   Makino, H ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b HIROSHIMA CITY HOSPITAL   (Japan)

Author keywords

Desmin; Elderly patients; Membranous glomerulonephritis; Nephrin; Nephrotic syndrome

Indexed keywords

DESMIN; GLUCOCORTICOID; NEPHRIN;

ADULT; AGED; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE CLASSIFICATION; DISEASE SEVERITY; ELECTRON MICROSCOPY; FEMALE; GLOMERULOPATHY; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; MAJOR CLINICAL STUDY; MALE; MEMBRANOUS GLOMERULONEPHRITIS; NEPHROTIC SYNDROME; PHENOTYPE; PODOCYTE; PREVALENCE; PROTEIN EXPRESSION; PROTEINURIA; UPREGULATION;

EID: 34547828145     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/cnp68073     Document Type: Article

References (16)

1. Ehrenreich T, Churg J. Pathology of membranous nephropathy. Pathol Annu. 1968; 3: 145-186.
2. Haas M, Meehan SM, Karrison TG, Spargo BH. Changing etiologies of unexplained adult nephrotic syndrome: a comparison of renal biopsy findings from 1976-1979 and 1995-1997. Am J Kidney Dis. 1997; 30: 621-631.
3. Ichinose K, Maeshima Y, Yamamoto Y, Kitayama H, Takazawa Y, Hirokoshi K, Sugiyama H, Yamasaki Y, Eguchi K, Makino H. Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a Type 1 diabetic nephropathy model. Diabetes. 2005; 54: 2891-2903.
4. Kobayashi M, Sugiyama H, Wang DH, Toda N, Maeshima Y, Yamasaki Y, Masuoka N, Yamada M, Kira S, Makino H. Catalase deficiency renders remnant kidneys more susceptible to oxidant tissue injury and renal fibrosis in mice. Kidney Int. 2005; 68: 1018-1031.
5. MacPherson BR, Leslie KO, Lizaso KV, Schwarz JE. Contractile cells of the kidney in primary glomerular disorders: an immunohistochemical study using an anti-α-smooth muscle actin monoclonal antibody. Hum Pathol. 1993; 24: 710-716.
6. Makino H, Sugiyama H, Yamasaki Y, Maeshima Y, Wada J, Kashihara N. Glomerular cell apoptosis in human lupus nephritis. Virchows Arch. 2003; 443: 67-77.
7. Mundel P, Shankland SJ. Podocyte biology and response to injury. J Am Soc Nephrol. 2002; 13: 3005-3015.
8. Nakatsue T, Koike H, Han GD, Suzuki K, Miyauchi N, Yuan H, Salant DJ, Gejyo F, Shimizu F, Kawachi H. Nephrin and podocin dissociate at the onset of proteinuria in experimental membranous nephropathy. Kidney Int. 2005; 67: 2239-2253.
9. Nangaku M, Shankland SJ, Couser WG. Cellular response to injury in membranous nephropathy. J Am Soc Nephrol. 2005; 16: 1195-1204.
10. Schena FP. Survey of the Italian Registry of Renal Biopsies. Frequency of the renal diseases for 7 consecutive years. The Italian Group of Renal Immunopathology. Nephrol Dial Transplant. 1997; 12: 418-426.
11. Shiiki H, Saito T, Nishitani Y, Mitarai T, Yorioka N, Yoshimura A, Yokoyama H, Nishi S, Tomino Y, Kurokawa K, Sakai H. Prognosis and risk factors for idiopathic membranous nephropathy with nephrotic syndrome in Japan. Kidney Int. 2004; 65: 1400-1407.
12. Stamenkovic I, Skalli O, Gabbiani G. Distribution of intermediate filament proteins in normal and diseased human glomeruli. Am J Pathol. 1986; 125: 465-475.
13. Sugiyama H, Kashihara N, Makino H, Yamasaki Y, Ota A. Apoptosis in glomerular sclerosis. Kidney Int. 1996; 49: 103-111.
14. Van Muijen GN, Ruiter DJ, Warnaar SO. Coexpression of intermediate filament polypeptides in human fetal and adult tissues. Lab Invest. 1987; 57: 359-369.
15. Yaoita E, Kawasaki K, Yamamoto T, Kihara I. Variable expression of desmin in rat glomerular epithelial cells. Am J Pathol. 1990; 136: 899-908.
16. Yoshimoto K, Yokoyama H, Wada T, Furuichi K, Sakai N, Iwata Y, Goshima S, Kida H. Pathologic findings of initial biopsies reflect the outcomes of membranous nephropathy. Kidney Int. 2004; 65: 148-153.