SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells

Stem Cells

Volumn 30, Issue 5, 2012, Pages 865-875

  Kele, Julianna ^a   Andersson, Emma R ^a   Villaescusa, J Carlos ^a   Cajanek, Lukas ^a   Parish, Clare L ^b   Bonilla, Sonia ^a   Toledo, Enrique M ^a   Bryja, Vitezslav ^a   Rubin, Jeffrey S ^c   Shimono, Akihiko ^d   Arenas, Ernest ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c NATIONAL CANCER INSTITUTE   (United States)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Developmental biology; Embryonic stem cells; Neural differentiation; Parkinson's disease

Indexed keywords

NUCLEAR RECEPTOR RELATED FACTOR 1; RAC1 PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; SONIC HEDGEHOG PROTEIN; WNT5A PROTEIN;

ANIMAL CELL; ARTICLE; CELL POLARITY; CELL SURVIVAL; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; EMBRYONIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; MESENCEPHALON; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PHENOTYPE; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; VENTRAL MIDBRAIN;

ANIMALS; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC STEM CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MESENCEPHALON; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; WNT PROTEINS;

MUS;

EID: 84860505844     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1049     Document Type: Article

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