TLR tolerance reduces IFN-alpha production despite plasmacytoid dendritic cell expansion and anti-nuclear antibodies in NZB bicongenic mice

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Pau, Evelyn ^a,b   Cheung, Yui Ho ^a,b   Loh, Christina ^a,b   Lajoie, Ginette ^c   Wither, Joan E ^a,b,d  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c William Osler Health Centre   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTINUCLEAR ANTIBODY; B CELL ACTIVATING FACTOR; IMMUNOGLOBULIN A; INTERLEUKIN 10; MESSENGER RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; IMMUNOGLOBULIN G;

ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BONE MARROW; C57BL 6 MOUSE; CELL EXPANSION; CELL STIMULATION; CELLULAR PARAMETERS; CONGENIC STRAIN; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION REGULATION; IMMUNOGLOBULIN PRODUCTION; IN VIVO STUDY; MOUSE; MYELOID DENDRITIC CELL; NEW ZEALAND BLACK MOUSE; NONHUMAN; PHENOTYPE; PLASMACYTOID DENDRITIC CELL; SPLEEN CELL; TLR TOLERANCE; ANIMAL; BIOSYNTHESIS; BLOOD; BONE MARROW CELL; CELL COUNT; CYTOLOGY; DENDRITIC CELL; FEMALE; HUMAN; IMMUNOLOGY; METABOLISM; SECRETION; SPLEEN; SYSTEMIC LUPUS ERYTHEMATOSUS;

MUS;

ANIMALS; ANTIBODIES, ANTINUCLEAR; BONE MARROW CELLS; CELL COUNT; DENDRITIC CELLS; FEMALE; HUMANS; IMMUNOGLOBULIN G; INTERFERON-ALPHA; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MICE, CONGENIC; SPLEEN; TOLL-LIKE RECEPTORS;

EID: 84860504571     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036761     Document Type: Article

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