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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 10, 2012, Pages 3516-3521

Long-acting peptidomimetics based DPP-IV inhibitors

(9) Jadav, Pradip a,b Bahekar, Rajesh a Shah, Shailesh R b Patel, Dipam a Joharapurkar, Amit a Kshirsagar, Samadhan a Jain, Mukul a Shaikh, Mubeen a Sairam, Kalapatapu V V M a

a ZYDUS RESEARCH CENTRE (India)

b M S UNIVERSITY OF BARODA (India)

Author keywords

Antidiabetic; DPP IV inhibitors; Long acting; Peptidomimetic; Selectivity; Slow binding

Indexed keywords

6 [[2 [[2 (2 CYANO 1 PYRROLIDINYL) 2 OXOETHYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; PEPTIDOMIMETIC AGENT; PYRROLIDINECARBONITRILE DERIVATIVE; UNCLASSIFIED DRUG; VILDAGLIPTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG HALF LIFE; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; HYPOGLYCEMIC AGENTS; MICE; MICE, INBRED C57BL; PEPTIDOMIMETICS;

EID: 84860480412 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.03.078 Document Type: Article

Times cited : (29)

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