Overweight is not a comorbidity factor during childhood asthma: The GrowthOb study

European Respiratory Journal

Volumn 39, Issue 5, 2012, Pages 1120-1126

  Mahut, Bruno ^a,b,e   Beydon, Nicole ^b,c   Delclaux, Christophe ^a,b,d  

^a HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^b Mosquito Respiratory Research Group   (France)

^c ARMAND TROUSSEAU HOSPITAL   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e Cabinet La Berma   (France)

Author keywords

Body mass index; Lung function; Lung volumes; Obesity; Z score

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID;

ADOLESCENT; ARTICLE; ASTHMA; ATOPY; BMI Z SCORE; BODY MASS; BODY WEIGHT; CHILD; COMORBIDITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE EXACERBATION; DYSPNEA; EXERCISE TOLERANCE; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; FUNCTIONAL RESIDUAL CAPACITY; GROWTH ACCELERATION; HUMAN; INTERNATIONAL OBESITY TASK FORCE GRADE; LUNG FUNCTION; LUNG VOLUME; MAJOR CLINICAL STUDY; MALE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; OBESITY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUBERTY; RESIDUAL VOLUME; RESPIRATORY AIRFLOW; SCHOOL CHILD; TOTAL LUNG CAPACITY;

ADOLESCENT; ANTI-ASTHMATIC AGENTS; ASTHMA; BODY MASS INDEX; CHILD; COMORBIDITY; FEMALE; HUMANS; LUNG; MALE; OVERWEIGHT; RESPIRATORY FUNCTION TESTS; SEVERITY OF ILLNESS INDEX;

EID: 84860467732     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00103311     Document Type: Article

References (51)

1. Camargo CA Jr, Weiss ST, Zhang S, et al. Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med 1999; 159: 2582-2588.
2. Figueroa-Munoz JI, Chinn S, Rona RJ. Association between obesity and asthma in 4-11 year old children in the UK. Thorax 2001; 56: 133-137. (Pubitemid 32142678)
3. de Groot EP, Duiverman EJ, Brand PL. Comorbidities of asthma during childhood. possibly important, yet poorly studied. Eur Respir J 2010; 36: 671-678.
4. Carroll CL, Bhandari A, Zucker AR, et al. Childhood obesity increases duration of therapy during severe asthma exacerbations. Pediatr Crit Care Med 2006; 7: 527-531. (Pubitemid 44715289)
5. Carroll CL, Stoltz P, Raykov N, et al. Childhood overweight increases hospital admission rates for asthma. Pediatrics 2007; 120: 734-740. (Pubitemid 47549560)
6. Vargas PA, Perry TT, Robles E, et al. Relationship of body mass index with asthma indicators in head start children. Ann Allergy Asthma Immunol 2007; 99: 22-28. (Pubitemid 47075946)
7. Kwong KY, Rhandhawa I, Saxena J, et al. Ability to control persistent asthma in obese versus non-obese children enrolled in an asthma-specific disease management program (breathmobile). J Asthma 2006; 43: 661-666. (Pubitemid 44722122)
8. Tantisira KG, Litonjua AA, Weiss ST, et al. Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax 2003; 58: 1036-1041. (Pubitemid 37542107)
9. Kattan M, Kumar R, Bloomberg GR, et al. Asthma control, adiposity, and adipokines among inner-city adolescents. J Allergy Clin Immunol 2010; 125: 584-592.
10. Cole TJ, Bellizzi MC, Flegal KM, et al. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000; 320: 1240-1243. (Pubitemid 30240471)
11. Cole TJ, Freeman JV, Preece MA. Body mass index reference curves for the UK, 1990. Arch Dis Child 1995; 73: 25-29.
12. He QQ, Wong TW, Du L, et al. Respiratory health in overweight and obese Chinese children. Pediatr Pulmonol 2009; 44: 997-1002.
13. Stanojevic S, Wade A, Cole TJ, et al. Spirometry centile charts for young Caucasian children: the Asthma UK Collaborative Initiative. Am J Respir Crit Care Med 2009; 180: 547-552.
14. The Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention, 2007. www.ginasthma.com Date last accessed October 15, 2009.
15. Mahut B, Peiffer C, Bokov P, et al. Use of specific airway resistance to assess bronchodilator response in children. Respirology 2011; 16: 666-671.
16. Reddel HK, Taylor DR, Bateman ED, et al. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med 2009; 180: 59-99.
17. Mahut B, Peiffer C, Thibaudon M, et al. What does a single exhaled nitric oxide measurement tell us in asthmatic children? J Asthma 2009; 46: 810-814.
18. Mahut B, Bokov P, Delclaux C. Abnormalities of plethysmographic lung volumes in asthmatic children. Respir Med 2010; 104: 966-971.
19. Mahut B, Trinquart L, Bokov P, et al. Relationships between specific airway resistance and forced expiratory flows in asthmatic children. PLoS One 2009; 4: e5270.
20. Stocks J, Quanjer PH. Reference values for residual volume, functional residual capacity and total lung capacity. ATS Workshop on Lung Volume Measurements. Official Statement of the European Respiratory Society. Eur Respir J 1995; 8: 492-506.
21. Benjamini Y, Yekutieli D. The control of the false discovery rate in multiple testing under dependency. Ann Stat 2001; 29: 1165-1188. (Pubitemid 33575263)
22. Hsieh FY, Bloch DA, Larsen MD. A simple method of sample size calculation for linear and logistic regression. Statist Med 1998; 17: 1623-1634. (Pubitemid 28367842)
23. Quanjer PH, Borsboom GJ, Kivastik J, et al. Cross-sectional and longitudinal spirometry in children and adolescents: interpretative strategies. Am J Respir Crit Care Med 2008; 178: 1262-1270.
24. Santamaria F, Montella S, Greco L, et al. Obesity duration is associated to pulmonary function impairment in obese subjects. Obesity (Silver Spring) 2011; 19: 1623-1628.
25. Beuther DA, Weiss ST, Sutherland ER. Obesity and asthma. Am J Respir Crit Care Med 2006; 174: 112-119. (Pubitemid 44015383)
26. Haldar P, Pavord ID, Shaw DE, et al. Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med 2008; 178: 218-224.
27. Simard B, Turcotte H, Marceau P, et al. Asthma and sleep apnea in patients with morbid obesity: outcome after bariatric surgery. Obes Surg 2004; 14: 1381-1388. (Pubitemid 39658326)
28. Sutherland ER, Lehman EB, Teodorescu M, et al. Body mass index and phenotype in subjects with mild-to-moderate persistent asthma. J Allergy Clin Immunol 2009; 123: 1328-1334.
29. Brasholt M, Baty F, Bisgaard H. Physical activity in young children is reduced with increasing bronchial responsiveness. J Allergy Clin Immunol 2011; 125: 1007-1012.
30. Scholtens S, Wijga AH, Seidell JC, et al. Overweight and changes in weight status during childhood in relation to asthma symptoms at 8 years of age. J Allergy Clin Immunol 2009; 123: 1312-1318.
31. Luder E, Melnik TA, DiMaio M. Association of being overweight with greater asthma symptoms in inner city black and Hispanic children. J Pediatr 1998; 132: 699-703. (Pubitemid 28194594)
32. Matricardi PM, Gruber C, Wahn U, et al. The asthma-obesity link in childhood: open questions, complex evidence, a few answers only. Clin Exp Allergy 2007; 37: 476-484. (Pubitemid 46537736)
33. Peroni DG, Pietrobelli A, Boner AL. Asthma and obesity in childhood: on the road ahead. Int J Obes (Lond) 2010; 34: 599-605.
34. Peters JI, McKinney JM, Smith B, et al. Impact of obesity in asthma: evidence from a large prospective disease management study. Ann Allergy Asthma Immunol 2011; 106: 30-35.
35. Dockery DW, Berkey CS, Ware JH, et al. Distribution of vital capacity and forced expiratory volume in one second in children 6 to 11 years of age. Am Rev Respir Dis 1983; 128: 405-412. (Pubitemid 13006136)
36. Chen Y, Rennie D, Cormier Y, et al. Waist circumference associated with pulmonary function in children. Pediatr Pulmonol 2009; 44: 216-221.
37. Schoenberg JB, Beck GJ, Bouhuys A. Growth and decay of pulmonary function in healthy blacks and whites. Respir Physiol 1978; 33: 367-393. (Pubitemid 9015918)
38. Lazarus R, Colditz G, Berkey CS, et al. Effects of body fat on ventilatory function in children and adolescents: cross-sectional findings from a random population sample of school children. Pediatr Pulmonol 1997; 24: 187-194. (Pubitemid 27431228)
39. Kaplowitz PB, Slora EJ, Wasserman RC, et al. Earlier onset of puberty in girls: relation to increased body mass index and race. Pediatrics 2001; 108: 347-353.
40. Merkus PJ, Borsboom GJ, Van Pelt W, et al. Growth of airways and air spaces in teenagers is related to sex but not to symptoms. J Appl Physiol 1993; 75: 2045-2053. (Pubitemid 23352375)
41. Covar RA, Spahn JD, Murphy JR, et al. Progression of asthma measured by lung function in the childhood asthma management program. Am J Respir Crit Care Med 2004; 170: 234-241. (Pubitemid 38971407)
42. Mahut B, Trinquart L, Bokov P, et al. Lung function impairment evidenced by sequential specific airway resistance in childhood persistent asthma: a longitudinal study. J Asthma 2010; 47: 655-659.
43. Collet F, Mallart A, Bervar JF, et al. Physiologic correlates of dyspnea in patients with morbid obesity. Int J Obes (Lond) 2007; 31: 700-706. (Pubitemid 46482350)
44. Inselma LS, Milanese A, Deurloo A. Effect of obesity on pulmonary function in children. Pediatr Pulmonol 1993; 16: 130-137.
45. Quanjer PH, Stanojevic S, Stocks J, et al. Changes in the FEV/FVC ratio during childhood and adolescence: an intercontinental study. Eur Respir J 2010; 36: 1391-1399.
46. Cotes JE, Dabbs JM, Hall AM, et al. Sitting height, fat-free mass and body fat as reference variables for lung function in healthy British children: comparison with stature. Ann Hum Biol 1979; 6: 307-314. (Pubitemid 10216731)
47. Neve V, Girard F, Flahault A, et al. Lung and thorax development during adolescence: relationship with pubertal status. Eur Respir J 2002; 20: 1292-1298. (Pubitemid 35331891)
48. Trabelsi Y, Tabka Z, Richalet JP, et al. Spirometric values in Tunisian children: relationship with pubertal status. Ann Hum Biol 2007; 34: 195-205. (Pubitemid 46895941)
49. Deschildre A, Pin I, Gueorguieva I, et al. Asthme et obé sité : quelle relation chez l'enfant? [Asthma and obesity in childhood: what is the link?]. Arch Pediatr 2009; 16: 1166-1174.
50. Jebb SA, Rennie KL, Cole TJ. Prevalence of overweight and obesity among young people in Great Britain. Public Health Nutr 2004; 7: 461-465. (Pubitemid 39277058)
51. Mahut B, Trinquart L, Delclaux C. Influence of age on the risk of severe exacerbation and asthma control in childhood. J Asthma 2011; 48: 65-68.