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Volumn 129, Issue 5, 2012, Pages 603-610

The inhibition of the integrin VLA-4 in MV3 melanoma cell binding by non-anticoagulant heparin derivatives

Author keywords

biosensor; cell adhesion; heparin; melanoma metastasis; VLA 4

Indexed keywords

ALPHA INTEGRIN; ENOXAPARIN; HEPARIN DERIVATIVE; L SELECTIN; NATALIZUMAB; PADGEM PROTEIN; TINZAPARIN; VERY LATE ACTIVATION ANTIGEN 4;

EID: 84860448186     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.10.023     Document Type: Article
Times cited : (20)

References (41)
  • 1
    • 77950593889 scopus 로고    scopus 로고
    • Cancer metastasis as a therapeutic target
    • J. Sleeman, and P.S. Steeg Cancer metastasis as a therapeutic target Eur J Cancer 46 2010 1177 1180
    • (2010) Eur J Cancer , vol.46 , pp. 1177-1180
    • Sleeman, J.1    Steeg, P.S.2
  • 2
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: Mechanistic insights and clinical challenges
    • P.S. Steeg Tumor metastasis: mechanistic insights and clinical challenges Nat Med 12 2006 895 904
    • (2006) Nat Med , vol.12 , pp. 895-904
    • Steeg, P.S.1
  • 3
    • 44349130354 scopus 로고    scopus 로고
    • ANTI-ADHESION evolves to a promising therapeutic concept in oncology
    • R. Schmidmaier, and P. Baumann ANTI-ADHESION evolves to a promising therapeutic concept in oncology Curr Med Chem 15 2008 978 990
    • (2008) Curr Med Chem , vol.15 , pp. 978-990
    • Schmidmaier, R.1    Baumann, P.2
  • 4
    • 77955482977 scopus 로고    scopus 로고
    • Antimetastatic activities of heparins and modified heparins. Experimental evidence
    • L. Borsig Antimetastatic activities of heparins and modified heparins. Experimental evidence Thromb Res 125 Suppl 2 2010 66 71
    • (2010) Thromb Res , vol.125 , Issue.SUPPL. 2 , pp. 66-71
    • Borsig, L.1
  • 5
    • 77956614939 scopus 로고    scopus 로고
    • Selectins promote tumor metastasis
    • H. Läubli, and L. Borsig Selectins promote tumor metastasis Semin Cancer Biol 20 Jun 2010 169 177
    • (2010) Semin Cancer Biol , vol.20 , pp. 169-177
    • Läubli, H.1    Borsig, L.2
  • 6
    • 16544390675 scopus 로고    scopus 로고
    • Endothelial P-selectin as a target of heparin action in experimental melanoma lung metastasis
    • R.J. Ludwig, B. Boehme, M. Podda, R. Henschler, E. Jager, and C. Tandi Endothelial P-selectin as a target of heparin action in experimental melanoma lung metastasis Cancer Res 64 2004 2743 2750
    • (2004) Cancer Res , vol.64 , pp. 2743-2750
    • Ludwig, R.J.1    Boehme, B.2    Podda, M.3    Henschler, R.4    Jager, E.5    Tandi, C.6
  • 7
    • 0035853111 scopus 로고    scopus 로고
    • Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
    • L. Borsig, R. Wong, J. Feramisco, D.R. Nadeau, N.M. Varki, and A. Varki Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis Proc Natl Acad Sci U S A 98 2001 3352 3357
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 3352-3357
    • Borsig, L.1    Wong, R.2    Feramisco, J.3    Nadeau, D.R.4    Varki, N.M.5    Varki, A.6
  • 8
    • 0033559946 scopus 로고    scopus 로고
    • Lysis of tumor cells by natural killer cells in mice is impeded by platelets
    • B. Nieswandt, M. Hafner, B. Echtenacher, and D.N. Männel Lysis of tumor cells by natural killer cells in mice is impeded by platelets Cancer Res 59 1999 1295 1300
    • (1999) Cancer Res , vol.59 , pp. 1295-1300
    • Nieswandt, B.1    Hafner, M.2    Echtenacher, B.3    Männel, D.N.4
  • 9
    • 32944476784 scopus 로고    scopus 로고
    • L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest
    • H. Läubli, J.L. Stevenson, A. Varki, N.M. Varki, and L. Borsig L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest Cancer Res 66 2006 1536 1542
    • (2006) Cancer Res , vol.66 , pp. 1536-1542
    • Läubli, H.1    Stevenson, J.L.2    Varki, A.3    Varki, N.M.4    Borsig, L.5
  • 10
    • 0032809670 scopus 로고    scopus 로고
    • Are selectins involved in metastasis?
    • T. Krause, and G.A. Turner Are selectins involved in metastasis? Clin Exp Metastasis 17 1999 183 192
    • (1999) Clin Exp Metastasis , vol.17 , pp. 183-192
    • Krause, T.1    Turner, G.A.2
  • 11
    • 57349172005 scopus 로고    scopus 로고
    • Melanoma cell adhesion can be blocked by heparin in vitro: Suggestion of VLA-4 as a novel target for antimetastatic approaches
    • J. Fritzsche, D. Simonis, and G. Bendas Melanoma cell adhesion can be blocked by heparin in vitro: suggestion of VLA-4 as a novel target for antimetastatic approaches Thromb Haemost 100 2008 1166 1175
    • (2008) Thromb Haemost , vol.100 , pp. 1166-1175
    • Fritzsche, J.1    Simonis, D.2    Bendas, G.3
  • 12
    • 0028179102 scopus 로고
    • Involvement of very late activation antigen 4 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) in tumor necrosis factor alpha enhancement of experimental metastasis
    • H. Okahara, H. Yagita, K. Miyake, and K. Okumura Involvement of very late activation antigen 4 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) in tumor necrosis factor alpha enhancement of experimental metastasis Cancer Res 54 1994 3233 3236
    • (1994) Cancer Res , vol.54 , pp. 3233-3236
    • Okahara, H.1    Yagita, H.2    Miyake, K.3    Okumura, K.4
  • 13
    • 53449090043 scopus 로고    scopus 로고
    • Integrin VLA-4 enhances sialyl-Lewisx/a-negative melanoma adhesion to and extravasation through the endothelium under low flow conditions
    • S. Liang, and C. Dong Integrin VLA-4 enhances sialyl-Lewisx/a-negative melanoma adhesion to and extravasation through the endothelium under low flow conditions Am J Physiol Cell Physiol 295 2008 701 707
    • (2008) Am J Physiol Cell Physiol , vol.295 , pp. 701-707
    • Liang, S.1    Dong, C.2
  • 14
    • 0028887370 scopus 로고
    • Involvement of the very late antigen 4 integrin on melanoma in interleukin 1-augmented experimental metastases
    • A. Garofalo, R.G. Chirivi, C. Foglieni, R. Pigott, R. Mortarini, and I. Martin-Padura Involvement of the very late antigen 4 integrin on melanoma in interleukin 1-augmented experimental metastases Cancer Res 55 1995 414 419
    • (1995) Cancer Res , vol.55 , pp. 414-419
    • Garofalo, A.1    Chirivi, R.G.2    Foglieni, C.3    Pigott, R.4    Mortarini, R.5    Martin-Padura, I.6
  • 15
    • 0028904388 scopus 로고
    • Association with clinical outcome of expression of VLA-4 in primary cutaneous malignant melanoma as well as P-selectin and E-selectin on intratumoral vessels
    • D. Schadendorf, J. Heidel, C. Gawlik, L. Suter, and B.M. Czarnetzki Association with clinical outcome of expression of VLA-4 in primary cutaneous malignant melanoma as well as P-selectin and E-selectin on intratumoral vessels J Natl Cancer Inst 87 1995 366 371
    • (1995) J Natl Cancer Inst , vol.87 , pp. 366-371
    • Schadendorf, D.1    Heidel, J.2    Gawlik, C.3    Suter, L.4    Czarnetzki, B.M.5
  • 16
    • 0037413240 scopus 로고    scopus 로고
    • Alpha4 integrins as therapeutic targets in autoimmune disease
    • U.H. von Andrian, and B. Engelhardt Alpha4 integrins as therapeutic targets in autoimmune disease N Engl J Med 348 2003 68 72
    • (2003) N Engl J Med , vol.348 , pp. 68-72
    • Von Andrian, U.H.1    Engelhardt, B.2
  • 18
    • 57349085011 scopus 로고    scopus 로고
    • Extended perioperative thromboprophylaxis in patients with cancer. A systematic review
    • E.A. Akl, I. Terrenato, M. Barba, F. Sperati, P. Muti, and H.J. Schünemann Extended perioperative thromboprophylaxis in patients with cancer. A systematic review Thromb Haemost 100 2008 1176 1180
    • (2008) Thromb Haemost , vol.100 , pp. 1176-1180
    • Akl, E.A.1    Terrenato, I.2    Barba, M.3    Sperati, F.4    Muti, P.5    Schünemann, H.J.6
  • 19
    • 79952257106 scopus 로고    scopus 로고
    • Parenteral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation
    • E.A. Akl, S. Gunukula, M. Barba, V.E.D. Yosuico, F.F. van Doormaal, and S. Kuipers Parenteral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation Cochrane Database Syst Rev 1 2011 CD006652
    • (2011) Cochrane Database Syst Rev , vol.1 , pp. 006652
    • Akl, E.A.1    Gunukula, S.2    Barba, M.3    Yosuico, V.E.D.4    Van Doormaal, F.F.5    Kuipers, S.6
  • 20
    • 49649114635 scopus 로고    scopus 로고
    • Low molecular weight heparins as extended prophylaxis against recurrent thrombosis in cancer patients
    • C.A. Engman, and L.R. Zacharski Low molecular weight heparins as extended prophylaxis against recurrent thrombosis in cancer patients J Natl Compr Canc Netw 6 2008 637 645
    • (2008) J Natl Compr Canc Netw , vol.6 , pp. 637-645
    • Engman, C.A.1    Zacharski, L.R.2
  • 21
    • 35948980396 scopus 로고    scopus 로고
    • P-selectin- and heparanase-dependent antimetastatic activity of non-anticoagulant heparins
    • N. Hostettler, A. Naggi, G. Torri, R. Ishai-Michaeli, B. Casu, and I. Vlodavsky P-selectin- and heparanase-dependent antimetastatic activity of non-anticoagulant heparins FASEB J 21 2007 3562 3572
    • (2007) FASEB J , vol.21 , pp. 3562-3572
    • Hostettler, N.1    Naggi, A.2    Torri, G.3    Ishai-Michaeli, R.4    Casu, B.5    Vlodavsky, I.6
  • 22
    • 4544370585 scopus 로고    scopus 로고
    • Inhibition of endothelial cell tube formation by the low molecular weight heparin, tinzaparin, is mediated by tissue factor pathway inhibitor
    • S.A. Mousa, and S. Mohamed Inhibition of endothelial cell tube formation by the low molecular weight heparin, tinzaparin, is mediated by tissue factor pathway inhibitor Thromb Haemost 92 2004 627 633
    • (2004) Thromb Haemost , vol.92 , pp. 627-633
    • Mousa, S.A.1    Mohamed, S.2
  • 23
    • 0031032234 scopus 로고    scopus 로고
    • Heparin oligosaccharides: Inhibitors of the biological activity of bFGF on Caco-2 cells
    • G.C. Jayson, and J.T. Gallagher Heparin oligosaccharides: inhibitors of the biological activity of bFGF on Caco-2 cells Br J Cancer 75 1997 9 16
    • (1997) Br J Cancer , vol.75 , pp. 9-16
    • Jayson, G.C.1    Gallagher, J.T.2
  • 25
    • 79952144802 scopus 로고    scopus 로고
    • Heparin plays a key regulatory role via a p53/FAK-dependent signaling in melanoma cell adhesion and migration
    • G. Chalkiadaki, D. Nikitovic, A. Berdiaki, P. Katonis, N.K. Karamanos, and G.N. Tzanakakis Heparin plays a key regulatory role via a p53/FAK-dependent signaling in melanoma cell adhesion and migration IUBMB Life 63 2011 109 119
    • (2011) IUBMB Life , vol.63 , pp. 109-119
    • Chalkiadaki, G.1    Nikitovic, D.2    Berdiaki, A.3    Katonis, P.4    Karamanos, N.K.5    Tzanakakis, G.N.6
  • 26
    • 20144388264 scopus 로고    scopus 로고
    • Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting
    • A. Naggi, B. Casu, M. Perez, G. Torri, G. Cassinelli, and S. Penco Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting J Biol Chem 280 2005 12103 12113
    • (2005) J Biol Chem , vol.280 , pp. 12103-12113
    • Naggi, A.1    Casu, B.2    Perez, M.3    Torri, G.4    Cassinelli, G.5    Penco, S.6
  • 27
    • 70449556920 scopus 로고    scopus 로고
    • Structural features of low-molecular-weight heparins affecting their affinity to antithrombin
    • A. Bisio, D. Vecchietti, L. Citterio, M. Guerrini, R. Raman, and S. Bertini Structural features of low-molecular-weight heparins affecting their affinity to antithrombin Thromb Haemost 102 2009 865 873
    • (2009) Thromb Haemost , vol.102 , pp. 865-873
    • Bisio, A.1    Vecchietti, D.2    Citterio, L.3    Guerrini, M.4    Raman, R.5    Bertini, S.6
  • 29
    • 0017342653 scopus 로고
    • Active amino acid transport in plasma membrane vesicles from Simian virus 40-transformed mouse fibroblasts. Characteristics of electrochemical Na + gradient-stimulated uptake
    • J.E. Lever Active amino acid transport in plasma membrane vesicles from Simian virus 40-transformed mouse fibroblasts. Characteristics of electrochemical Na + gradient-stimulated uptake J Biol Chem 252 1977 1990 1997
    • (1977) J Biol Chem , vol.252 , pp. 1990-1997
    • Lever, J.E.1
  • 30
    • 0022229182 scopus 로고
    • Determination of microgram quantities of protein in the presence of milligram levels of lipid with amido black 10B
    • R.S. Kaplan, and P.L. Pedersen Determination of microgram quantities of protein in the presence of milligram levels of lipid with amido black 10B Anal Biochem 150 1985 97 104
    • (1985) Anal Biochem , vol.150 , pp. 97-104
    • Kaplan, R.S.1    Pedersen, P.L.2
  • 31
    • 64749105270 scopus 로고    scopus 로고
    • Molecular basis of metastasis
    • 1679-80
    • A. Varki, N.M. Varki, and L. Borsig Molecular basis of metastasis N Engl J Med 360 2009 1678 1679 1679-80
    • (2009) N Engl J Med , vol.360 , pp. 1678-1679
    • Varki, A.1    Varki, N.M.2    Borsig, L.3
  • 32
    • 34347393710 scopus 로고    scopus 로고
    • High affinity interaction of integrin alpha4beta1 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) enhances migration of human melanoma cells across activated endothelial cell layers
    • M. Klemke, T. Weschenfelder, M.H. Konstandin, and Y. Samstag High affinity interaction of integrin alpha4beta1 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) enhances migration of human melanoma cells across activated endothelial cell layers J Cell Physiol 212 2007 368 374
    • (2007) J Cell Physiol , vol.212 , pp. 368-374
    • Klemke, M.1    Weschenfelder, T.2    Konstandin, M.H.3    Samstag, Y.4
  • 33
    • 79959220996 scopus 로고    scopus 로고
    • Bioactivity screening of partially desulfated low-molecular-weight heparins: A structure/activity relationship study
    • S. Roy, H. Lai, R. Zouaoui, J. Duffner, H. Zhou, and L.P. Jayaraman Bioactivity screening of partially desulfated low-molecular-weight heparins: a structure/activity relationship study Glycobiology 21 2011 1194 1205
    • (2011) Glycobiology , vol.21 , pp. 1194-1205
    • Roy, S.1    Lai, H.2    Zouaoui, R.3    Duffner, J.4    Zhou, H.5    Jayaraman, L.P.6
  • 34
    • 34249075408 scopus 로고    scopus 로고
    • Kinetic analysis of heparin and glucan sulfates binding to P-selectin and its impact on the general understanding of selectin inhibition
    • D. Simonis, J. Fritzsche, S. Alban, and G. Bendas Kinetic analysis of heparin and glucan sulfates binding to P-selectin and its impact on the general understanding of selectin inhibition Biochemistry 46 2007 6156 6164
    • (2007) Biochemistry , vol.46 , pp. 6156-6164
    • Simonis, D.1    Fritzsche, J.2    Alban, S.3    Bendas, G.4
  • 35
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • B.-Z. Qian, and J.W. Pollard Macrophage diversity enhances tumor progression and metastasis Cell 141 2010 39 51
    • (2010) Cell , vol.141 , pp. 39-51
    • Qian, B.-Z.1    Pollard, J.W.2
  • 36
    • 0036308072 scopus 로고    scopus 로고
    • Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins
    • L. Wang, J.R. Brown, A. Varki, and J.D. Esko Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins J Clin Invest 110 2002 127 136
    • (2002) J Clin Invest , vol.110 , pp. 127-136
    • Wang, L.1    Brown, J.R.2    Varki, A.3    Esko, J.D.4
  • 37
    • 3142708942 scopus 로고    scopus 로고
    • Modified heparin inhibits P-selectin-mediated cell adhesion of human colon carcinoma cells to immobilized platelets under dynamic flow conditions
    • M. Wei, G. Tai, Y. Gao, N. Li, B. Huang, and Y. Zhou Modified heparin inhibits P-selectin-mediated cell adhesion of human colon carcinoma cells to immobilized platelets under dynamic flow conditions J Biol Chem 279 2004 29202 29210
    • (2004) J Biol Chem , vol.279 , pp. 29202-29210
    • Wei, M.1    Tai, G.2    Gao, Y.3    Li, N.4    Huang, B.5    Zhou, Y.6
  • 38
    • 78649868172 scopus 로고    scopus 로고
    • Study on anti-metastasis of heparin derivatives as ligand antagonist of p-selectin
    • Y. Li, J.-Y. Luo, H.-F. Cui, L. Zheng, and S. Du Study on anti-metastasis of heparin derivatives as ligand antagonist of p-selectin Biomed Pharmacother 64 2010 654 658
    • (2010) Biomed Pharmacother , vol.64 , pp. 654-658
    • Li, Y.1    Luo, J.-Y.2    Cui, H.-F.3    Zheng, L.4    Du, S.5
  • 39
    • 72949100109 scopus 로고    scopus 로고
    • Antimigratory and antimetastatic effect of heparin-derived 4-18 unit oligosaccharides in a preclinical human melanoma metastasis model
    • I. Kenessey, E. Simon, K. Futosi, B. Bereczky, A. Kiss, and F. Erdödi Antimigratory and antimetastatic effect of heparin-derived 4-18 unit oligosaccharides in a preclinical human melanoma metastasis model Thromb Haemost 102 2009 1265 1273
    • (2009) Thromb Haemost , vol.102 , pp. 1265-1273
    • Kenessey, I.1    Simon, E.2    Futosi, K.3    Bereczky, B.4    Kiss, A.5    Erdödi, F.6
  • 40
    • 0032519957 scopus 로고    scopus 로고
    • Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents
    • A. Koenig, K. Norgard-Sumnicht, R. Linhardt, and A. Varki Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents J Clin Invest 101 1998 877 889
    • (1998) J Clin Invest , vol.101 , pp. 877-889
    • Koenig, A.1    Norgard-Sumnicht, K.2    Linhardt, R.3    Varki, A.4


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