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Volumn 31, Issue 14, 2012, Pages 1794-1803

Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells

Author keywords

Erk; gene expression; MYC; Pim1 kinase; tumorigenicity

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; PROTEIN KINASE PIM 1;

EID: 84860423643     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.371     Document Type: Article
Times cited : (69)

References (31)
  • 3
    • 3343007095 scopus 로고    scopus 로고
    • 112 gatekeeper site
    • DOI 10.1016/j.febslet.2004.06.050, PII S0014579304008026
    • Aho TL, Sandholm J, Peltola KJ, Mankonen HP, Lilly M, Koskinen PJ. (2004). Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site. FEBS Lett 571: 43-49. (Pubitemid 38992921)
    • (2004) FEBS Letters , vol.571 , Issue.1-3 , pp. 43-49
    • Aho, T.L.T.1    Sandholm, J.2    Peltola, K.J.3    Mankonen, H.P.4    Lilly, M.5    Koskinen, P.J.6
  • 4
    • 0033118764 scopus 로고    scopus 로고
    • Identification and characterization of collaborating oncogenes in compound mutant mice
    • Berns A, Mikkers H, Krimpenfort P, Allen J, Scheijen B, Jonkers J. (1999). Identification and characterization of collaborating oncogenes in compound mutant mice. Cancer Res 59: 1773s-1777s. (Pubitemid 29165253)
    • (1999) Cancer Research , vol.59 , Issue.7 SUPPL.
    • Berns, A.1    Mikkers, H.2    Krimpenfort, P.3    Allen, J.4    Scheijen, B.5    Jonkers, J.6
  • 5
    • 1642313751 scopus 로고    scopus 로고
    • Microarray analysis of differentiation-specific gene expression during 3T3-L1 adipogenesis
    • DOI 10.1016/j.gene.2003.12.012, PII S0378111903011533
    • Burton GR, Nagarajan R, Peterson CA, McGehee Jr RE. (2004). Microarray analysis of differentiation-specific gene expression during 3T3-L1 adipogenesis. Gene 329: 167-185. (Pubitemid 38366505)
    • (2004) Gene , vol.329 , Issue.1-2 , pp. 167-185
    • Burton, G.R.1    Nagarajan, R.2    Peterson, C.A.3    McGehee Jr., R.E.4
  • 6
    • 67649969176 scopus 로고    scopus 로고
    • Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation
    • Chen J, Kobayashi M, Darmanin S, Qiao Y, Gully C, Zhao R et al. (2009a). Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation. Am J Pathol 175: 400-411.
    • (2009) Am J Pathol , vol.175 , pp. 400-411
    • Chen, J.1    Kobayashi, M.2    Darmanin, S.3    Qiao, Y.4    Gully, C.5    Zhao, R.6
  • 7
    • 77950538522 scopus 로고    scopus 로고
    • Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells
    • Chen LS, Redkar S, Bearss D, Wierda WG, Gandhi V. (2009b). Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells. Blood 114: 4150-4157.
    • (2009) Blood , vol.114 , pp. 4150-4157
    • Chen, L.S.1    Redkar, S.2    Bearss, D.3    Wierda, W.G.4    Gandhi, V.5
  • 8
    • 24144458232 scopus 로고    scopus 로고
    • Pim family kinases enhance tumor growth of prostate cancer cells
    • DOI 10.1158/1541-7786.MCR-05-0007
    • Chen WW, Chan DC, Donald C, Lilly MB, Kraft AS. (2005). Pim family kinases enhance tumor growth of prostate cancer cells. Mol Cancer Res 3: 443-451. (Pubitemid 41232606)
    • (2005) Molecular Cancer Research , vol.3 , Issue.8 , pp. 443-451
    • Chen, W.W.1    Chan, D.C.2    Donald, C.3    Lilly, M.B.4    Kraft, A.S.5
  • 9
    • 0027315650 scopus 로고
    • A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice
    • Davis AC, Wims M, Spotts GD, Hann SR, Bradley A. (1993). A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice. Genes Dev 7: 671-682. (Pubitemid 23125266)
    • (1993) Genes and Development , vol.7 , Issue.4 , pp. 671-682
    • Davis, A.C.1    Wims, M.2    Spotts, G.D.3    Hann, S.R.4    Bradley, A.5
  • 10
    • 69549086437 scopus 로고    scopus 로고
    • Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration
    • Grundler R, Brault L, Gasser C, Bullock AN, Dechow T, Woetzel S et al. (2009). Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration. J Exp Med 206: 1957-1970.
    • (2009) J Exp Med , vol.206 , pp. 1957-1970
    • Grundler, R.1    Brault, L.2    Gasser, C.3    Bullock, A.N.4    Dechow, T.5    Woetzel, S.6
  • 11
    • 71349086917 scopus 로고    scopus 로고
    • PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis
    • Gu JJ, Wang Z, Reeves R, Magnuson NS. (2009). PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis. Oncogene 28: 4261-4271.
    • (2009) Oncogene , vol.28 , pp. 4261-4271
    • Gu, J.J.1    Wang, Z.2    Reeves, R.3    Magnuson, N.S.4
  • 12
    • 61749092591 scopus 로고    scopus 로고
    • PIM-1-specific mAb suppresses human and mouse tumor growth by decreasing PIM-1 levels, reducing Akt phosphorylation, and activating apoptosis
    • Hu XF, Li J, Vandervalk S, Wang Z, Magnuson NS, Xing PX. (2009). PIM-1-specific mAb suppresses human and mouse tumor growth by decreasing PIM-1 levels, reducing Akt phosphorylation, and activating apoptosis. J Clin Invest 119: 362-375.
    • (2009) J Clin Invest , vol.119 , pp. 362-375
    • Hu, X.F.1    Li, J.2    Vandervalk, S.3    Wang, Z.4    Magnuson, N.S.5    Xing, P.X.6
  • 13
    • 77449103988 scopus 로고    scopus 로고
    • Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis
    • Jager J, Gremeaux T, Gonzalez T, Bonnafous S, Debard C, Laville M et al. (2010). Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis. Diabetes 59: 61-70.
    • (2010) Diabetes , vol.59 , pp. 61-70
    • Jager, J.1    Gremeaux, T.2    Gonzalez, T.3    Bonnafous, S.4    Debard, C.5    Laville, M.6
  • 14
    • 77952841717 scopus 로고    scopus 로고
    • Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity
    • Kim J, Roh M, Abdulkadir SA. (2010). Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity. BMC Cancer 10: 248.
    • (2010) BMC Cancer , vol.10 , pp. 248
    • Kim, J.1    Roh, M.2    Abdulkadir, S.A.3
  • 15
    • 0034667593 scopus 로고    scopus 로고
    • Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
    • Kolch W. (2000). Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J 351(Part 2): 289-305.
    • (2000) Biochem J , vol.351 , Issue.PART 2 , pp. 289-305
    • Kolch, W.1
  • 17
    • 36849013629 scopus 로고    scopus 로고
    • Human prostate cancer cells express neuroendocrine cell markers PGP 9.5 and chromogranin A
    • DOI 10.1002/pros.20654
    • Leiblich A, Cross SS, Catto JW, Pesce G, Hamdy FC, Rehman I. (2007). Human prostate cancer cells express neuroendocrine cell markers PGP 9.5 and chromogranin A. Prostate 67: 1761-1769. (Pubitemid 350228728)
    • (2007) Prostate , vol.67 , Issue.16 , pp. 1761-1769
    • Leiblich, A.1    Cross, S.S.2    Catto, J.W.F.3    Pesce, G.4    Hamdy, F.C.5    Rehman, I.6
  • 18
    • 77957967569 scopus 로고    scopus 로고
    • Why target PIM1 for cancer diagnosis and treatment?
    • Magnuson NS, Wang Z, Ding G, Reeves R. (2010). Why target PIM1 for cancer diagnosis and treatment? Future Oncol 6: 1461-1478.
    • (2010) Future Oncol , vol.6 , pp. 1461-1478
    • Magnuson, N.S.1    Wang, Z.2    Ding, G.3    Reeves, R.4
  • 19
    • 2942700011 scopus 로고    scopus 로고
    • Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors
    • DOI 10.1128/MCB.24.13.6104-6115.2004
    • Mikkers H, Nawijn M, Allen J, Brouwers C, Verhoeven E, Jonkers J et al. (2004). Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors. Mol Cell Biol 24: 6104-6115. (Pubitemid 38787993)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.13 , pp. 6104-6115
    • Mikkers, H.1    Nawijn, M.2    Allen, J.3    Brouwers, C.4    Verhoeven, E.5    Jonkers, J.6    Berns, A.7
  • 21
    • 48549096958 scopus 로고    scopus 로고
    • Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels
    • Morishita D, Katayama R, Sekimizu K, Tsuruo T, Fujita N. (2008). Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels. Cancer Res 68: 5076-5085.
    • (2008) Cancer Res , vol.68 , pp. 5076-5085
    • Morishita, D.1    Katayama, R.2    Sekimizu, K.3    Tsuruo, T.4    Fujita, N.5
  • 22
    • 70350218944 scopus 로고    scopus 로고
    • Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes
    • Mumenthaler SM, Ng PY, Hodge A, Bearss D, Berk G, Kanekal S et al. (2009). Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes. Mol Cancer Ther 8: 2882-2893.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2882-2893
    • Mumenthaler, S.M.1    Ng, P.Y.2    Hodge, A.3    Bearss, D.4    Berk, G.5    Kanekal, S.6
  • 25
    • 53249137796 scopus 로고    scopus 로고
    • Potential roles for the PIM1 kinase in human cancer - A molecular and therapeutic appraisal
    • Shah N, Pang B, Yeoh KG, Thorn S, Chen CS, Lilly MB et al. (2008). Potential roles for the PIM1 kinase in human cancer - a molecular and therapeutic appraisal. Eur J Cancer 44: 2144-2151.
    • (2008) Eur J Cancer , vol.44 , pp. 2144-2151
    • Shah, N.1    Pang, B.2    Yeoh, K.G.3    Thorn, S.4    Chen, C.S.5    Lilly, M.B.6
  • 29
    • 77951879645 scopus 로고    scopus 로고
    • Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma
    • Wang J, Kim J, Roh M, Franco OE, Hayward SW, Wills ML et al. (2010). Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma. Oncogene 29: 2477-2487.
    • (2010) Oncogene , vol.29 , pp. 2477-2487
    • Wang, J.1    Kim, J.2    Roh, M.3    Franco, O.E.4    Hayward, S.W.5    Wills, M.L.6
  • 30
    • 49649127162 scopus 로고    scopus 로고
    • Pim kinase-dependent inhibition of c-Myc degradation
    • Zhang Y, Wang Z, Li X, Magnuson NS. (2008). Pim kinase-dependent inhibition of c-Myc degradation. Oncogene 27: 4809-4819.
    • (2008) Oncogene , vol.27 , pp. 4809-4819
    • Zhang, Y.1    Wang, Z.2    Li, X.3    Magnuson, N.S.4
  • 31
    • 34547599505 scopus 로고    scopus 로고
    • PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation
    • DOI 10.1038/ncb1618, PII NCB1618
    • Zippo A, De Robertis A, Serafini R, Oliviero S. (2007). PIM1- dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation. Nat Cell Biol 9: 932-944. (Pubitemid 47190448)
    • (2007) Nature Cell Biology , vol.9 , Issue.8 , pp. 932-944
    • Zippo, A.1    De Robertis, A.2    Serafini, R.3    Oliviero, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.