Impact of HMG-CoA reductase inhibition on oxidant-induced injury in human retinal pigment epithelium cells

Journal of Cellular Biochemistry

Volumn 112, Issue 9, 2011, Pages 2480-2489

  Qian, Jinqiao ^a,b   Keyes, Kyle T ^a   Long, Bo ^a   Chen, Guanglin ^a   Ye, Yumei ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Oxidative stress; p38; ROS; RPE

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; CASPASE 3; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; NICK END LABELING; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CASPASE 3; CELL LINE; CELL SURVIVAL; ENZYME ACTIVATION; EPITHELIAL CELLS; HEPTANOIC ACIDS; HUMANS; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MAP KINASE SIGNALING SYSTEM; NADPH OXIDASE; OXIDANTS; OXIDATIVE STRESS; PYRROLES; RETINAL PIGMENT EPITHELIUM; SIMVASTATIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84860403984     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23173     Document Type: Article

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