Pyocyanin-induced toxicity in A549 respiratory cells is causally linked to oxidative stress

Toxicology in Vitro

Volumn 25, Issue 7, 2011, Pages 1353-1358

  Gloyne, Lee S ^a   Grant, Gary D ^a   Perkins, Anthony V ^a   Powell, Katie L ^a   McDermott, Catherine M ^b   Johnson, Peter V ^b   Anderson, Gregory J ^c   Kiefel, Milton ^a   Anoopkumar Dukie, Shailendra ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b BOND UNIVERSITY   (Australia)

^c QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

A549 respiratory epithelial cells; Glutathione; Oxidative stress; Pseudomonas aeruginosa; Pyocyanin

Indexed keywords

ACETYLCYSTEINE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PYOCYANINE; REACTIVE OXYGEN METABOLITE; RESAZURIN; RESORUFIN;

ARTICLE; CELL COUNT; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LUNG INFECTION; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PNEUMONIA; PROTEIN EXPRESSION; PSEUDOMONAS INFECTION;

CELL LINE, TUMOR; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GLUTATHIONE; GLUTATHIONE DISULFIDE; HUMANS; HYDROGEN PEROXIDE; NF-KAPPA B; OXIDATIVE STRESS; PYOCYANINE; RESPIRATORY MUCOSA;

MAMMALIA; PSEUDOMONAS AERUGINOSA;

EID: 84860389327     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.05.004     Document Type: Article

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