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Bioorganic and Medicinal Chemistry

Volumn 19, Issue 17, 2011, Pages 5147-5154

Ligand polarizability contributes to tau fibril binding affinity

(4) Jensen, Jordan R a Cisek, Katryna a Honson, Nicolette S a,b Kuret, Jeff a

a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE (United States)

b Centre for Drug Research and Development (Canada)

Author keywords

Alzheimer's disease; Dispersion forces; Polarizability; Tau protein

Indexed keywords

AMINE; BENZOTHIAZOLE; OXINDOLE; PHENOTHIAZINE; RECOMBINANT PROTEIN; TAU PROTEIN; THIOFLAVINE; TRIARYLMETHINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; BRAIN TISSUE; DRUG STRUCTURE; HIGH THROUGHPUT SCREENING; LIGAND BINDING; NEUROFILAMENT; PAIRED HELICAL FILAMENT; POLARIZATION; PROTEIN BINDING;

ALZHEIMER DISEASE; BENZOTHIAZOLES; BINDING SITES; HUMANS; INDOLES; LIGANDS; PHENOTHIAZINES; PROTEIN BINDING; TAU PROTEINS; THIAZOLES;

EID: 84860389168 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2011.07.016 Document Type: Article

Times cited : (14)

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