The distant organ effects of acute kidney injury

Kidney International

Volumn 81, Issue 10, 2012, Pages 942-948

  Grams, Morgan E ^a   Rabb, Hamid ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute kidney injury; Extrarenal complications; Inflammation; Pathophysiology

Indexed keywords

AQUAPORIN 5; CREATININE; EPITHELIAL SODIUM CHANNEL; INTERLEUKIN 6; INTERLEUKIN 8;

ACUTE KIDNEY FAILURE; ADULT RESPIRATORY DISTRESS SYNDROME; APOPTOSIS; ARTICLE; BLOOD VESSEL PERMEABILITY; CHANNEL GATING; CYTOKINE RELEASE; DISEASE ASSOCIATION; DISEASE SEVERITY; DISTANT ORGAN INJURY; HEART DISEASE; INFLAMMATION; KIDNEY ISCHEMIA; LEUKOCYTE COUNT; LIVER DISEASE; LUNG DISEASE; LUNG INJURY; MORBIDITY; MORTALITY; NEUROLOGIC DISEASE; NONHUMAN; ORGAN INJURY; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS;

EID: 84860382951     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.241     Document Type: Article

References (64)

1. Thakar CV, Christianson A, Freyberg R et al. Incidence and outcomes of acute kidney injury in intensive care units: A veterans administration study. Crit Care Med 2009; 37: 2552-2558.
2. Uchino S, Kellum JA, Bellomo R et al. Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 2005; 294: 813-818.
3. Waikar SS, Liu KD, Chertow GM. Diagnosis, epidemiology and outcomes of acute kidney injury. Clin J Am Soc Nephrol 2008; 3: 844-861.
4. Liano F, Pascual J. Epidemiology of acute renal failure: a prospective, multicenter, community-based study. madrid acute renal failure study group. Kidney Int 1996; 50: 811-818.
5. Mehta RL, Pascual MT, Soroko S et al. Program to Improve Care in Acute Renal Disease. Spectrum of acute renal failure in the intensive care unit: the PICARD experience. Kidney Int 2004; 66: 1613-1621.
6. Star RA. Treatment of acute renal failure. Kidney Int 1998; 54: 1817-1831.
7. Ympa YP, Sakr Y, Reinhart K et al. Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med 2005; 118: 827-832.
8. VA/NIH Acute Renal Failure Trial Network, Palevsky PM, Zhang JH, O'Connor TZ et al. Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 2008; 359: 7-20.
9. Levy EM, Viscoli CM, Horwitz RI. The effect of acute renal failure on mortality. A cohort analysis. JAMA 1996; 275: 1489-1494.
10. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342: 1301-1308.
11. The ARDS network. Ketoconazole for early treatment of acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA 2000; 283: 1995-2002.
12. Liu KD, Glidden DV, Eisner MD et al. National Heart, Lung, and Blood Institute ARDS Network Clinical Trials Group. Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. Crit Care Med 2007; 35: 2755-2761.
13. Schaefer JH, Jochimsen F, Keller F et al. Outcome prediction of acute renal failure in medical intensive care. Intensive Care Med 1991; 17: 19-24.
14. Chertow GM, Christiansen CL, Cleary PD et al. Prognostic stratification in critically ill patients with acute renal failure requiring dialysis. Arch Intern Med 1995; 155: 1505-1511.
15. Waikar SS, Liu KD, Chertow GM. The incidence and prognostic significance of acute kidney injury. Curr Opin Nephrol Hypertens 2007; 16: 227-236.
16. Chawla LS, Seneff MG, Nelson DR et al. Elevated plasma concentrations of IL-6 and elevated APACHE II score predict acute kidney injury in patients with severe sepsis. Clin J Am Soc Nephrol 2007; 2: 22-30.
17. Liu KD, Altmann C, Smits G et al. Serum interleukin-6 and interleukin-8 are early biomarkers of acute kidney injury and predict prolonged mechanical ventilation in children undergoing cardiac surgery: a case-control study. Crit Care 2009; 13: R104.
18. Liangos O, Kolyada A, Tighiouart H et al. Interleukin-8 and acute kidney injury following cardiopulmonary bypass: A prospective cohort study. Nephron Clin Pract 2009; 113: c148-c154.
19. Kwon O, Molitoris BA, Pescovitz M et al. Urinary actin, interleukin-6, and interleukin-8 may predict sustained ARF after ischemic injury in renal allografts. Am J Kidney Dis 2003; 41: 1074-1087.
20. Simmons EM, Himmelfarb J, Sezer MT, et al., PICARD Study Group. Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int 2004; 65: 1357-1365.
21. Meduri GU, Headley S, Kohler G et al. Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1 beta and IL-6 levels are consistent and efficient predictors of outcome over time. Chest 1995; 107: 1062-1073.
22. Kramer AA, Postler G, Salhab KF et al. Renal ischemia/reperfusion leads to macrophage-mediated increase in pulmonary vascular permeability. Kidney Int 1999; 55: 2362-2367.
23. Hoke TS, Douglas IS, Klein CL et al. Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury. J Am Soc Nephrol 2007; 18: 155-164.
24. Nath KA, Grande JP, Croatt AJ et al. Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury. Am J Pathol 2005; 166: 963-972.
25. Rabb H, Wang Z, Nemoto T et al. Acute renal failure leads to dysregulation of lung salt and water channels. Kidney Int 2003; 63: 600-606.
26. Deng J, Hu X, Yuen PS et al. Alpha-melanocyte-stimulating hormone inhibits lung injury after renal ischemia/reperfusion. Am J Respir Crit Care Med 2004; 169: 749-756.
27. Klein CL, Hoke TS, Fang WF et al. Interleukin-6 mediates lung injury following ischemic acute kidney injury or bilateral nephrectomy. Kidney Int 2008; 74: 901-909.
28. Tracz MJ, Juncos JP, Croatt AJ et al. Deficiency of heme oxygenase-1 impairs renal hemodynamics and exaggerates systemic inflammatory responses to renal ischemia. Kidney Int 2007; 72: 1073-1080.
29. Kim DJ, Park SH, Sheen MR et al. Comparison of experimental lung injury from acute renal failure with injury due to sepsis. Respiration 2006; 73: 815-824.
30. Hassoun HT, Grigoryev DN, Lie ML et al. Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy. Am J Physiol Renal Physiol 2007; 293: F30-F40.
31. Hassoun HT, Lie ML, Grigoryev DN et al. Kidney ischemia-reperfusion injury induces caspase-dependent pulmonary apoptosis. Am J Physiol Renal Physiol 2009; 297: F125-F137.
32. Awad AS, Rouse M, Huang L et al. Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury. Kidney Int 2009; 75: 689-698.
33. Zarbock A, Schmolke M, Spieker T et al. Acute uremia but not renal inflammation attenuates aseptic acute lung injury: A critical role for uremic neutrophils. J Am Soc Nephrol 2006; 17: 3124-3131.
34. Imai Y, Parodo J, Kajikawa O et al. Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA 2003; 289: 2104-2112.
35. Hoag JB, Liu M, Easley RB et al. Effects of acid aspiration-induced acute lung injury on kidney function. Am J Physiol Renal Physiol 2008; 294: F900-F908.
36. Ronco C, Haapio M, House AA et al. Cardiorenal syndrome. J Am Coll Cardiol 2008; 52: 1527-1539.
37. Mehta RL, Kellum JA, Shah SV, et al., Acute Kidney Injury Network. Acute kidney injury network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007; 11: R31.
38. Damman K, Jaarsma T, Voors AA, et al., COACH investigators. Both in-and out-hospital worsening of renal function predict outcome in patients with heart failure: Results from the coordinating study evaluating outcome of advising and counseling in heart failure (COACH). Eur J Heart Fail 2009; 11: 847-854.
39. Jorres A, Gahl GM, Dobis C et al. Haemodialysis-membrane biocompatibility and mortality of patients with dialysis-dependent acute renal failure: a prospective randomised multicentre trial. International Multicentre Study Group. Lancet 1999; 354: 1337-1341.
40. Kelly KJ. Acute renal failure: much more than a kidney disease. Semin Nephrol 2006; 26: 105-113.
41. Testa M, Yeh M, Lee P et al. Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension. J Am Coll Cardiol 1996; 28: 964-971.
42. Deswal A, Petersen NJ, Feldman AM et al. Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the vesnarinone trial (VEST). Circulation 2001; 103: 2055-2059.
43. Vasan RS, Sullivan LM, Roubenoff R, et al., Framingham Heart Study. Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: The framingham heart study. Circulation 2003; 107: 1486-1491.
44. Setsuta K, Seino Y, Ogawa T et al. Ongoing myocardial damage in chronic heart failure is related to activated tumor necrosis factor and Fas/Fas ligand system. Circ J 2004; 68: 747-750.
45. Nishigaki K, Minatoguchi S, Seishima M et al. Plasma fas ligand, an inducer of apoptosis, and plasma soluble fas, an inhibitor of apoptosis, in patients with chronic congestive heart failure. J Am Coll Cardiol 1997; 29: 1214-1220.
46. Kelly KJ. Distant effects of experimental renal ischemia/reperfusion injury. J Am Soc Nephrol 2003; 14: 1549-1558.
47. Francoz C, Glotz D, Moreau R et al. The evaluation of renal function and disease in patients with cirrhosis. J Hepatol 2010; 52: 605-613.
48. Oliver JA, Verna EC. Afferent mechanisms of sodium retention in cirrhosis and hepatorenal syndrome. Kidney Int 2010; 77: 669-680.
49. Miyazawa S, Watanabe H, Miyaji C et al. Leukocyte accumulation and changes in extra-renal organs during renal ischemia reperfusion in mice. J Lab Clin Med 2002; 139: 269-278.
50. Golab F, Kadkhodaee M, Zahmatkesh M et al. Ischemic and non-ischemic acute kidney injury cause hepatic damage. Kidney Int 2009; 75: 783-792.
51. Park SW, Chen SW, Kim M et al. Cytokines induce small intestine and liver injury after renal ischemia or nephrectomy. Lab Invest 2011; 91: 63-84.
52. Serteser M, Koken T, Kahraman A et al. Changes in hepatic TNF-alpha levels, antioxidant status, and oxidation products after renal ischemia/reperfusion injury in mice. J Surg Res 2002; 107: 234-240.
53. Burn DJ, Bates D. Neurology and the kidney. J Neurol Neurosurg Psychiatry 1998; 65: 810-821.
54. Brouns R, De Deyn PP. Neurological complications in renal failure: a review. Clin Neurol Neurosurg 2004; 107: 1-16.
55. Fraser CL, Arieff AI. Nervous system complications in uremia. Ann Intern Med 1988; 109: 143-153.
56. Zacharia BE, Ducruet AF, Hickman ZL et al. Renal dysfunction as an independent predictor of outcome after aneurysmal subarachnoid hemorrhage: a single-center cohort study. Stroke 2009; 40: 2375-2381.
57. Tsagalis G, Akrivos T, Alevizaki M et al. Long-term prognosis of acute kidney injury after first acute stroke. Clin J Am Soc Nephrol 2009; 4: 616-622.
58. de Vries DK, Lindeman JH, Ringers J et al. Donor brain death predisposes human kidney grafts to a proinflammatory reaction after transplantation. Am J Transplant 2011; 11: 1064-1070.
59. Arieff AI, Massry SG. Calcium metabolism of brain in acute renal failure. Effects of uremia, hemodialysis, and parathyroid hormone. J Clin Invest 1974; 53: 387-392.
60. Arieff AI, Guisado R, Massry SG. Uremic encephalopathy: studies on biochemical alterations in the brain. Kidney Int Suppl 1975; 2): 194-200.
61. Pollock AS, Arieff AI. Abnormalities of cell volume regulation and their functional consequences. Am J Physiol 1980; 239: F195-F205.
62. Adachi N, Lei B, Deshpande G et al. Uraemia suppresses central dopaminergic metabolism and impairs motor activity in rats. Intensive Care Med 2001; 27: 1655-1660.
63. Liu M, Liang Y, Chigurupati S et al. Acute kidney injury leads to inflammation and functional changes in the brain. J Am Soc Nephrol 2008; 19: 1360-1370.
64. Scheel PJ, Liu M, Rabb H. Uremic lung: new insights into a forgotten condition. Kidney Int 2008; 74: 849-851.