Proteasome inhibition can impair caspase-8 activation upon submaximal stimulation of apoptotic tumor necrosis factor-related apoptosis inducing ligand (TRAIL) signaling

Journal of Biological Chemistry

Volumn 287, Issue 18, 2012, Pages 14402-14411

  Laussmann, Maike A ^a   Passantes, Egle ^a   Hellwigs, Christian T ^a   Tomiczek, Bartołmiej ^a   Flanagans, Lorna ^a   Prehns, Jochen H M ^a   Hubers, Heinrich J ^a   Rehms, Markus ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC; BORTEZOMIB; CASPASES; CERVICAL CANCER CELLS; CURRENT MODELS; DEATH-INDUCING SIGNALING COMPLEXES; MODELING RESULTS; PROTEASOME INHIBITORS; PROTEASOMES; PROTEIN LEVEL; RELATIVE ABUNDANCE; SIGNALING PROTEINS; SINGLE CELLS; TIME-LAPSE IMAGING; TUMOR NECROSIS;

CORE LEVELS; GLYCOPROTEINS; LIGANDS; MACROPHAGES; SIGNAL TRANSDUCTION; SIGNALING; TRANSCRIPTION;

CELL DEATH;

BORTEZOMIB; CASPASE 3; CASPASE 8; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; EPOXOMICIN; PROTEASOME; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BORONIC ACIDS; CASPASE 8; ENZYME ACTIVATION; HELA CELLS; HUMANS; OLIGOPEPTIDES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRAZINES; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84860372597     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.304378     Document Type: Article

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