Global transcriptional changes of Clostridium acetobutylicum cultures with increased butanol: Acetone ratios

New Biotechnology

Volumn 29, Issue 4, 2012, Pages 485-493

  Hönicke, Daniel ^a,b   Janssen, Holger ^a   Grimmler, Christina ^c   Ehrenreich, Armin ^b,c   Lütke Eversloh, Tina ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE-BUTANOL-ETHANOL FERMENTATION; BATCH FERMENTATION; BIFUNCTIONAL; CELLULAR REDOX; CLOSTRIDIUM ACETOBUTYLICUM; CONTROL CULTURES; DNA MICROARRAY ANALYSIS; ELECTRON CARRIER; EXPRESSION LEVELS; GENE EXPRESSION PATTERNS; GENES CODING; METABOLIC PATHWAYS; METHYL VIOLOGEN; MINERAL SALTS MEDIUMS; MOLECULAR LEVELS; RIBOFLAVIN BIOSYNTHESIS; SERUM BOTTLES; SOLVENT FORMATION; SOLVENTOGENIC CLOSTRIDIA; SUGAR TRANSPORT; TRANSCRIPTIONAL CHANGES; TRANSCRIPTIONAL REGULATION;

ACETONE; ALCOHOLS; BIOCHEMISTRY; BIOSYNTHESIS; ETHANOL; FERMENTATION; GENE EXPRESSION; HYDROGEN PRODUCTION; MOLECULAR BIOLOGY; SOLS; SUGARS;

ORGANIC SOLVENTS;

ABC TRANSPORTER; ACETONE; ADENYLLYLSULFATE REDUCTASE; BACTERIAL PROTEIN; BUTANOL; FERREDOXIN; GLUTAMINE AMIDOTRANSFERASE; O ACETYLHOMOSERINE SULFHYDRYLASE; PYRIDOXINE BIOSYNTHESIS PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SOLVENT; UNCLASSIFIED DRUG; VIOLOGEN;

ARTICLE; BACTERIUM CULTURE; BATCH FERMENTATION; BIOREACTOR; CLOSTRIDIUM ACETOBUTYLICUM; DNA MICROARRAY; GENE EXPRESSION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL;

ACETONE; ALDEHYDE DEHYDROGENASE; BACTERIAL PROTEINS; BUTANOLS; CLOSTRIDIUM ACETOBUTYLICUM; FERMENTATION; GENE EXPRESSION PROFILING; ION TRANSPORT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARAQUAT; RIBOFLAVIN; UP-REGULATION;

CLOSTRIDIA; CLOSTRIDIUM ACETOBUTYLICUM;

EID: 84860367333     PISSN: 18716784     EISSN: 18764347     Source Type: Journal    
DOI: 10.1016/j.nbt.2012.01.001     Document Type: Article

References (52)

1. Jones D.T., Woods D.R. Acetone-butanol fermentation revisited. Microbiol. Rev. 1986, 50:484-524.
2. Ezeji T.C., et al. Bioproduction of butanol from biomass: from genes to bioreactors. Curr. Opin. Biotechnol. 2007, 18:220-227.
3. Green E.M. Fermentative production of butanol - the industrial perspective. Curr. Opin. Biotechnol. 2011, 22:337-343.
4. Lee S.Y., et al. Fermentative butanol production by clostridia. Biotechnol. Bioeng. 2008, 101:209-228.
5. Gheshlaghi R., et al. Metabolic pathways of clostridia for producing butanol. Biotechnol. Adv. 2009, 27:764-781.
6. Girbal L., Soucaille P. Regulation of solvent production in Clostridium acetobutylicum. Trends Biotechnol. 1998, 16:11-16.
7. Lütke-Eversloh T., Bahl H. Metabolic engineering of Clostridium acetobutylicum: recent advances to improve butanol production. Curr. Opin. Biotechnol. 2011, 22:634-647.
8. Han B., et al. Acetone production in solventogenic Clostridium species: new insights from non-enzymatic decarboxylation of acetoacetate. Appl. Microbiol. Biotechnol. 2011, 91:565-576.
9. Demuez M., et al. Complete activity profile of Clostridium acetobutylicum [FeFe]-hydrogenase and kinetic parameters for endogenous redox partners. FEMS Microbiol. Lett. 2007, 275:113-121.
10. Petitdemange H., et al. Regulation of the NADH and NADPH ferredoxin oxidoreductases in Clostridia of the butyric group. Biochim. Biophys. Acta 1976, 421:334-347.
11. Petitdemange H., et al. NADH and NADPH ferredoxin oxidoreductase activities in Clostridium acetobutylicum. Can. J. Microbiol. 1977, 23:152-160.
12. Blusson H., et al. A new, fast, and sensitive assay for NADH-ferredoxin oxidoreductase detection in clostridia. Anal. Biochem. 1981, 110:176-181.
13. Li F., et al. Coupled ferredoxin and crotonyl coenzyme A (CoA) reduction with NADH catalyzed by the butyryl-CoA dehydrogenase/Etf complex from Clostridium kluyveri. J. Bacteriol. 2008, 190:843-850.
14. Herrmann G., et al. Energy conservation via electron-transferring flavoprotein in anaerobic bacteria. J. Bacteriol. 2008, 190:784-791.
15. + reduction with NADH are coupled via an electron-bifurcating enzyme complex in Clostridium kluyveri. J. Bacteriol. 2010, 192:5115-5123.
16. Biegel E., et al. Biochemistry evolution and physiological function of the Rnf complex, a novel ion-motive electron transport complex in prokaryotes. Cell. Mol. Life Sci. 2011, 68:613-634.
17. Monot F., et al. Acetone and butanol production by Clostridium acetobutylicum in a synthetic medium. Appl. Environ. Microbiol. 1982, 44:1318-1324.
18. Lehmann D., Lütke-Eversloh T. Switching Clostridium acetobutylicum to an ethanol producer by disruption of the butyrate/butanol fermentative pathway. Metab. Eng. 2011, 13:464-473.
19. Thormann K., et al. Control of butanol formation in Clostridium acetobutylicum by transcriptional activation. J. Bacteriol. 2002, 184:1966-1973.
20. Fischer R.J., et al. Transcription of the pst operon of Clostridium acetobutylicum is dependent on phosphate concentration and pH. J. Bacteriol. 2006, 188:5469-5478.
21. 2-affected gene expression of Clostridium acetobutylicum. J. Bacteriol. 2009, 191:6082-6093.
22. Grimmler C., et al. Genome-wide gene expression analysis of the switch between acidogenesis and solventogenesis in continuous cultures of Clostridium acetobutylicum. J. Mol. Microbiol. Biotechnol. 2011, 20:1-15.
23. Bahl H., et al. Nutritional factors affecting the ratio of solvents procuded by Clostridium acetobutylicum. Appl. Environ. Microbiol. 1986, 52:169-172.
24. Vasconcelos I., et al. Regulation of carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH on mixtures of glucose and glycerol. J. Bacteriol. 1994, 176:1443-1450.
25. Girbal L., Soucaille P. Regulation of Clostridium acetobutylicum metabolism as revealed by mixed substrate steady-state continuous cultures: role of NADH/NAD ratio and ATP pool. J. Bacteriol. 1994, 176:6433-6438.
26. Sonomoto K., et al. Efficient conversion of lactic acid to butanol with pH-stat continuous lactic acid and glucose feeding method by Clostridium saccharoperbutylacetonicum. Appl. Microbiol. Biotechnol. 2010, 87:1177-1185.
27. Girbal L., et al. Regulation of metabolic shifts in Clostridium acetobutylicum ATCC 824. FEMS Microbiol. Rev. 1995, 17:287-297.
28. Heap J.T., et al. The ClosTron. A universal gene knock-out system for the genus Clostridium. J. Microbiol. Meth. 2007, 70:452-464.
29. Nölling J., et al. Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum. J. Bacteriol. 2001, 183:4823-4838.
30. Tomas C.A., et al. DNA array-based transcriptional analysis of asporogenous, nonsolventogenic Clostridium acetobutylicum strains SKO1 and M5. J. Bacteriol. 2003, 185:4539-4547.
31. Alsaker K.V., et al. Design, optimization and validation of genomic DNA microarrays for examining the Clostridium acetobutylicum transcriptome. Biotechnol. Bioprocess. Eng. 2005, 10:432-443.
32. Guerrini O., et al. Characterization of two 2[4Fe4S] ferredoxins from Clostridium acetobutylicum. Curr. Microbiol. 2008, 56:261-267.
33. Worst D.J., et al. Helicobacter pylori ribBA-mediated riboflavin production is involved in iron acquisition. J. Bacteriol. 1998, 180:1473-1479.
34. Crossley R.A., et al. Riboflavin biosynthesis is associated with assimilatory ferric reduction and iron acquisition by Campylobacter jejuni. Appl. Environ. Microbiol. 2007, 73:7819-7825.
35. Von Canstein H., et al. Secretion of flavins by Shewanella species and their role in extracellular electron transfer. Appl. Environ. Microbiol. 2008, 74:615-623.
36. Kim J., et al. Dehydration of (R)-2-hydroxyacyl-CoA to enoyl-CoA in the fermentation of alpha-amino acids by anaerobic bacteria. FEMS Microbiol. Rev. 2004, 28:455-468.
37. Andersch W., et al. Levels of enzymes involved in acetate, butyrate, acetone and butanol formation by Clostridium acetobutylicum. Eur. J. Appl. Microbiol. Biotechnol. 1983, 18:327-332.
38. Santangelo J.D., et al. Characterization and expression of the hydrogenase-encoding gene from Clostridium acetobutylicum P262. Microbiology 1995, 141:171-180.
39. Gorwa M.F., et al. Molecular characterization and transcriptional analysis of the putative hydrogenase gene of Clostridium acetobutylicum ATCC 824. J. Bacteriol. 1996, 178:2668-2675.
40. Jones S.W., et al. The transcriptional program underlying the physiology of clostridial sporulation. Genome Biol. 2008, 9:R114.
41. Nakayama S.I., et al. Metabolic Engineering for solvent productivity by downregulation of the hydrogenase gene cluster hupCBA in Clostridium saccharoperbutylacetonicum strain N1-4. Appl. Microbiol. Biotechnol. 2008, 78:483-493.
42. Janssen H., et al. A proteomic and transcriptional view of acidogenic and solventogenic steady-state cells of Clostridium acetobutylicum in a chemostat culture. Appl. Microbiol. Biotechnol. 2010, 87:2209-2226.
43. Sauer U., Dürre P. Differential induction of genes related to solvent formation during the shift from acidogenesis to solventogenesis in continuous culture of Clostridium acetobutylicum. FEMS Microbiol. Lett. 1995, 125:115-120.
44. Fontaine L., et al. Molecular characterization and transcriptional analysis of adhE2, the gene encoding the NADH-dependent aldehyde/alcohol dehydrogenase responsible for butanol production in alcohologenic cultures of Clostridium acetobutylicum ATCC 824. J. Bacteriol. 2002, 184:821-830.
45. Jiang Y., et al. Disruption of the acetoacetate decarboxylase gene in solvent-producing Clostridium acetobutylicum increases the butanol ratio. Metab. Eng. 2009, 11:284-291.
46. Doremus M.G., et al. Agitation and pressure effects on acetone-butanol fermentation. Biotechnol. Bioeng. 1985, 27:852-860.
47. Kim B.H., et al. Control of carbon and electron flow in Clostridium acetobutylicum fermentations: utilization of carbon monoxide to inhibit hydrogen production and to enhance butanol yields. Appl. Environ. Microbiol. 1984, 48:764-770.
48. Datta R., Zeikus J.G. Modulation of acetone-butanol-ethanol fermentation by carbon monoxide and organic acids. Appl. Environ. Microbiol. 1985, 49:522-529.
49. Junelles A.M., et al. Iron effect on acetone-butanol fermentation. Curr. Microbiol. 1988, 17:299-303.
50. Wang S., et al. Controlling the oxidoreduction potential of the culture of Clostridium acetobutylicum leads to an earlier initiation of solventogenesis, thus increasing solvent productivity. Appl. Microbiol. Biotechnol. 2011, 10.1007/s00253-011-3570-2.
51. Peguin S., et al. Metabolic flexibility of Clostridium acetobytylicum in response to methyl viologen addition. Appl. Microbiol. Biotechnol. 1994, 42:611-616.
52. Chauvatcharin S., et al. Metabolism analysis and on-line physiological state diagnosis of acetone-butanol fermentation. Biotechnol. Bioeng. 1998, 58:561-571.