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1
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34249993002
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Butanol production from agricultural residues: impact of degradation products on Clostridium beijerinckii growth and butanol fermentation
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[Epub ahead of print: DOI:10.1002/bit.21373]. This research article demonstrates the effect of compounds such as salts, furfural, hydroxymethyl furfural (HMF), acids (acetic, ferulic, glucuronic, p-coumaric), and phenolic compounds, which are potential degradation products generated during lignocellulosic biomass pretreatment and hydrolysis on cell growth and butanol production. Some of these inhibitory products negatively affect cell growth and butanol production by Clostridium beijerinckii. Furfural and HMF are not inhibitory to C. beijerinckii; rather they have a stimulatory effect on the growth of the microorganism and ABE production.
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Ezeji T.C., Qureshi N., and Blaschek H.P. Butanol production from agricultural residues: impact of degradation products on Clostridium beijerinckii growth and butanol fermentation. Biotechnol Bioeng (2007) [Epub ahead of print: DOI:10.1002/bit.21373]. This research article demonstrates the effect of compounds such as salts, furfural, hydroxymethyl furfural (HMF), acids (acetic, ferulic, glucuronic, p-coumaric), and phenolic compounds, which are potential degradation products generated during lignocellulosic biomass pretreatment and hydrolysis on cell growth and butanol production. Some of these inhibitory products negatively affect cell growth and butanol production by Clostridium beijerinckii. Furfural and HMF are not inhibitory to C. beijerinckii; rather they have a stimulatory effect on the growth of the microorganism and ABE production.
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(2007)
Biotechnol Bioeng
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Ezeji, T.C.1
Qureshi, N.2
Blaschek, H.P.3
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2
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10944238461
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Butanol fermentation research: upstream and downstream manipulations
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Ezeji T.C., Qureshi N., and Blaschek H.P. Butanol fermentation research: upstream and downstream manipulations. Chem Rec 4 (2004) 305-314
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(2004)
Chem Rec
, vol.4
, pp. 305-314
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Ezeji, T.C.1
Qureshi, N.2
Blaschek, H.P.3
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3
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0042726305
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Qureshi N, Blaschek HP: Economics of butanol fermentation using hyper-butanol producing Clostridium beijerinckii BA101. Trans IChemE 2000, 78(Part C):139-144.
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4
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0034902930
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Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum
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Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., et al. Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum. J Bacteriol 183 (2001) 4823-4838
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(2001)
J Bacteriol
, vol.183
, pp. 4823-4838
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Nolling, J.1
Breton, G.2
Omelchenko, M.V.3
Makarova, K.S.4
Zeng, Q.5
Gibson, R.6
Lee, H.M.7
Dubois, J.8
Qiu, D.9
Hitti, J.10
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5
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4644285450
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Substrate-induced production and secretion of cellulases by Clostridium acetobutylicum
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Lopez-Contreras A.M., Gabor K., Martens A.M., Renckens B.A.M., Claassen P.A.M., van der Oost J., Willem M., and de Vos W.M. Substrate-induced production and secretion of cellulases by Clostridium acetobutylicum. Appl Environ Microbiol 70 (2004) 5238-5243
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(2004)
Appl Environ Microbiol
, vol.70
, pp. 5238-5243
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Lopez-Contreras, A.M.1
Gabor, K.2
Martens, A.M.3
Renckens, B.A.M.4
Claassen, P.A.M.5
van der Oost, J.6
Willem, M.7
de Vos, W.M.8
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6
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73249147153
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Metabolic engineering of solventogenic clostridia
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Durre P. (Ed), CRC Press, Taylor & Francis Group, Boca Raton, Florida
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Tomas C.A., Tummala S.B., and Papoutsakis E.T. Metabolic engineering of solventogenic clostridia. In: Durre P. (Ed). Handbook on Clostridia (2005), CRC Press, Taylor & Francis Group, Boca Raton, Florida 813-830
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(2005)
Handbook on Clostridia
, pp. 813-830
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Tomas, C.A.1
Tummala, S.B.2
Papoutsakis, E.T.3
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7
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0032469479
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Physiology of carbohydrates to solvent conversion by clostridia
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Mitchell W.J. Physiology of carbohydrates to solvent conversion by clostridia. Adv Microb Physiol 39 (1998) 31-130
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(1998)
Adv Microb Physiol
, vol.39
, pp. 31-130
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Mitchell, W.J.1
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8
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33644858397
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Microbial conversion of glycerol to 1,3-propanediol: physiological comparison of a natural producer, Clostridium butyricum VPI 3266, and an engineered strain, Clostridium acetobutylicum DG1(pSPD5)
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González-Pajuelo M., Meynial-Salles I., Filipa Mendes F., Soucaille P., and Vasconcelos I. Microbial conversion of glycerol to 1,3-propanediol: physiological comparison of a natural producer, Clostridium butyricum VPI 3266, and an engineered strain, Clostridium acetobutylicum DG1(pSPD5). Appl Environ Microbiol 72 (2006) 96-101
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(2006)
Appl Environ Microbiol
, vol.72
, pp. 96-101
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González-Pajuelo, M.1
Meynial-Salles, I.2
Filipa Mendes, F.3
Soucaille, P.4
Vasconcelos, I.5
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10
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23844499442
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Optimization of pH controlled liquid hot water pretreatment of corn stover
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Mosier N., Hendrickson R., Ho N., Sedlak M., and Ladisch M.R. Optimization of pH controlled liquid hot water pretreatment of corn stover. Bioresour Technol 96 (2005) 1986-1993
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(2005)
Bioresour Technol
, vol.96
, pp. 1986-1993
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Mosier, N.1
Hendrickson, R.2
Ho, N.3
Sedlak, M.4
Ladisch, M.R.5
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11
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23844533296
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Optimization of the ammonia fiber explosion (AFEX) treatment parameters for enzymatic hydrolysis of corn stover
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This article demonstrates that a mild pretreatment method such as AFEX greatly enhances the digestibility of biomass and that high glucose and xylose yields are achievable even at low enzyme levels.
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Teymouri F., Laureano-Perez L., Alizadeh H., and Dale B.E. Optimization of the ammonia fiber explosion (AFEX) treatment parameters for enzymatic hydrolysis of corn stover. Bioresour Technol 96 (2005) 2014-2018. This article demonstrates that a mild pretreatment method such as AFEX greatly enhances the digestibility of biomass and that high glucose and xylose yields are achievable even at low enzyme levels.
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(2005)
Bioresour Technol
, vol.96
, pp. 2014-2018
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Teymouri, F.1
Laureano-Perez, L.2
Alizadeh, H.3
Dale, B.E.4
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12
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2242456844
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Glucose uptake in Clostridium beijerinckii NCIMB 8052 and the solvent-hyperproducing mutant BA101
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Lee J., and Blaschek H.P. Glucose uptake in Clostridium beijerinckii NCIMB 8052 and the solvent-hyperproducing mutant BA101. Appl Environ Microbiol 67 (2001) 5025-5031
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(2001)
Appl Environ Microbiol
, vol.67
, pp. 5025-5031
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Lee, J.1
Blaschek, H.P.2
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13
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20444388622
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Evidence for the presence of alternative glucose transport system in Clostridium beijerinckii NCIMB 8052 and the solvent-hyperproducing mutant BA101
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This study demonstrates that wild-type C. beijerinckii NCIMB 8052 and the mutant strain C. beijerinckii BA101 both have a PTS and a non-PTS uptake system for glucose, with their relative contributions to glucose accumulation being dependent on the physiological state of the cells.
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Lee J., Mitchell W.J., Tangney M., and Blaschek H.P. Evidence for the presence of alternative glucose transport system in Clostridium beijerinckii NCIMB 8052 and the solvent-hyperproducing mutant BA101. Appl Environ Microbiol 71 (2005) 3384-3387. This study demonstrates that wild-type C. beijerinckii NCIMB 8052 and the mutant strain C. beijerinckii BA101 both have a PTS and a non-PTS uptake system for glucose, with their relative contributions to glucose accumulation being dependent on the physiological state of the cells.
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(2005)
Appl Environ Microbiol
, vol.71
, pp. 3384-3387
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Lee, J.1
Mitchell, W.J.2
Tangney, M.3
Blaschek, H.P.4
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14
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0037337740
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Design of antisense RNA constructs for downregulation of the acetone formation pathway of Clostridium acetobutylicum
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Tummala S.B., Welker N.E., and Papoutsakis E.T. Design of antisense RNA constructs for downregulation of the acetone formation pathway of Clostridium acetobutylicum. J Bacteriol 185 (2003) 1923-1934
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(2003)
J Bacteriol
, vol.185
, pp. 1923-1934
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Tummala, S.B.1
Welker, N.E.2
Papoutsakis, E.T.3
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15
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0037608873
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Antisense RNA downregulation of coenzyme A transferase combined with alcohol-aldehyde deghydrogenase overexpression leads to predorminantly alchologenic Clostridium acetobutylicum fermentations
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Tummala S.B., Junne S.G., and Papoutsakis E.T. Antisense RNA downregulation of coenzyme A transferase combined with alcohol-aldehyde deghydrogenase overexpression leads to predorminantly alchologenic Clostridium acetobutylicum fermentations. J Bacteriol 185 (2003) 3644-3653
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(2003)
J Bacteriol
, vol.185
, pp. 3644-3653
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Tummala, S.B.1
Junne, S.G.2
Papoutsakis, E.T.3
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16
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85133997082
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Butanol production from agricultural biomass
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Shetty K., Pometto A., and Paliyath G. (Eds), Taylor & Francis Group plc, Boca Raton, FL
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Qureshi N., and Blaschek H.P. Butanol production from agricultural biomass. In: Shetty K., Pometto A., and Paliyath G. (Eds). Food Biotechnology (2005), Taylor & Francis Group plc, Boca Raton, FL 525-551
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(2005)
Food Biotechnology
, pp. 525-551
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Qureshi, N.1
Blaschek, H.P.2
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17
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34249986538
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Qureshi N, Ebener J, Ezeji TC, Dien B, Cotta MA, Blaschek HP: Butanol production by Clostridium beijerinckii BA101. Part I: Use of acid and enzyme hydrolysed corn fiber. Bioresouce Technol 2007: in press.
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18
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34250004757
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Qureshi N, Saha BC, Hughes SR, Cotta MA: Production of acetone butanol (AB) from agricultural residues using Clostridium acetobutylicum in batch reactors coupled with product recovery. Ninth International Workshop and Conference on the Regulation of Metabolism, Genetics and Development of the Solvent and Acid Forming Clostridia. Rice University, Houston, May 18-21, 2006. This presentation demonstrates that acetone butanol can be produced from hydrolysates of agricultural residues such as wheat straw. Using wheat straw hydrolysate (WSH), ABE productivity was improved by 214%. WSH supplemented with sugar was successfully fermented when coupled with a novel product recovery technique.
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19
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34250010187
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Butanol production from corn
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Minteer S.D. (Ed), Taylor & Francis, New York, NY
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Ezeji T.C., Qureshi N., Karcher P., and Blaschek H.P. Butanol production from corn. In: Minteer S.D. (Ed). Alcoholic Fuels: Fuels for Today and Tomorrow (2006), Taylor & Francis, New York, NY 99-122
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(2006)
Alcoholic Fuels: Fuels for Today and Tomorrow
, pp. 99-122
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Ezeji, T.C.1
Qureshi, N.2
Karcher, P.3
Blaschek, H.P.4
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20
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11244351994
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Continuous production of butanol by Clostridium acetobutylicum immobilized in a fibrous bed reactor
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Huang W.-C., Ramey D.E., and Yang S.-T. Continuous production of butanol by Clostridium acetobutylicum immobilized in a fibrous bed reactor. Appl Biochem Biotechnol 113 (2004) 887-898
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(2004)
Appl Biochem Biotechnol
, vol.113
, pp. 887-898
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Huang, W.-C.1
Ramey, D.E.2
Yang, S.-T.3
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21
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84994322409
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Industrially relevant fermentations
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Durre P. (Ed), CRC Press, Taylor & Francis Group, Boca Raton, Florida
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Ezeji T.C., Qureshi N., and Blaschek H.P. Industrially relevant fermentations. In: Durre P. (Ed). Handbook on Clostridia (2005), CRC Press, Taylor & Francis Group, Boca Raton, Florida 797-812
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(2005)
Handbook on Clostridia
, pp. 797-812
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Ezeji, T.C.1
Qureshi, N.2
Blaschek, H.P.3
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22
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34250019806
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Ezeji TC, Qureshi N, Blaschek HP: Process for continuous solvent production. U.S. Provisional Patent 2005, No. 60/504,280.
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23
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0041912376
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Production of butanol by Clostridium beijerinckii BA101 and in-situ recovery by gas stripping
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Ezeji T.C., Qureshi N., and Blaschek H.P. Production of butanol by Clostridium beijerinckii BA101 and in-situ recovery by gas stripping. World J Microbiol Biotechnol 19 (2003) 595-603
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(2003)
World J Microbiol Biotechnol
, vol.19
, pp. 595-603
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Ezeji, T.C.1
Qureshi, N.2
Blaschek, H.P.3
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24
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1542269174
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Acetone-butanol-ethanol production from concentrated substrate: reduction in substrate inhibition by fed-batch technique and product inhibition by gas stripping
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Ezeji T.C., Qureshi N., and Blaschek H.P. Acetone-butanol-ethanol production from concentrated substrate: reduction in substrate inhibition by fed-batch technique and product inhibition by gas stripping. Appl Microbiol Biotechnol 63 (2004) 653-658
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(2004)
Appl Microbiol Biotechnol
, vol.63
, pp. 653-658
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Ezeji, T.C.1
Qureshi, N.2
Blaschek, H.P.3
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25
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34249986980
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Microbial production of butanol: product recovery by extraction
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Satyanarayana T., and Johri B.N. (Eds), IK International Publishing House Pvt. Ltd, New Delhi
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Karcher P., Ezeji T.C., Qureshi N., and Blaschek H.P. Microbial production of butanol: product recovery by extraction. In: Satyanarayana T., and Johri B.N. (Eds). Microbial Diversity: Current Perspectives and Potential Applications (2005), IK International Publishing House Pvt. Ltd, New Delhi 865-880
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(2005)
Microbial Diversity: Current Perspectives and Potential Applications
, pp. 865-880
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Karcher, P.1
Ezeji, T.C.2
Qureshi, N.3
Blaschek, H.P.4
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26
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16244422708
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Qureshi N, Maddox IS: Reduction in butanol inhibition by perstraction: Utilization of concentrated lactose/whey permeate by Clostridium acetobutylicum to enhance butanol fermentation economics. Official Journal of the European Federation of Chemical Engineering (formerly Trans IChemE; Chemical Engineering Research & Design): Food and Bioproducts Processing. Part C 2005, 83(C1):43-52.
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27
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33745111655
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Butanol production from corn fiber xylan using Clostridium acetobutylicum
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Demonstrates that the integration of hydrolysis of corn fiber arabinoxylan, fermentation to ABE, and recovery of ABE in a single system is possible and economical. The paper is a definitive demonstration of the potential of ABE production from a biomass-based substrate.
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Qureshi N., Li X.-L., Hughes S., Saha B.C., and Cotta M.A. Butanol production from corn fiber xylan using Clostridium acetobutylicum. Biotechnol Prog 22 (2006) 673-680. Demonstrates that the integration of hydrolysis of corn fiber arabinoxylan, fermentation to ABE, and recovery of ABE in a single system is possible and economical. The paper is a definitive demonstration of the potential of ABE production from a biomass-based substrate.
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(2006)
Biotechnol Prog
, vol.22
, pp. 673-680
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Qureshi, N.1
Li, X.-L.2
Hughes, S.3
Saha, B.C.4
Cotta, M.A.5
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