Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1

Molecular Cancer

Volumn 11, Issue , 2012, Pages

  van der Weyden, Louise ^a   Arends, Mark J ^b   Rust, Alistair G ^a   Poulogiannis, George ^c   McIntyre, Rebecca E ^a   Adams, David J ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cell adhesion molecule; Cell junction; Glucocorticoid; Transposon; Tumor suppressor

Indexed keywords

CELL ADHESION MOLECULE; GENOMIC DNA; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN;

ADENOCARCINOMA; ADENOMA; ANGIOSARCOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL JUNCTION; FLOW CYTOMETRY; GENE INSERTION; GENOMIC INSTABILITY; HISTOLOGY; LEUKEMIA; LIVER CELL CARCINOMA; LYMPHOMA; MICRONUCLEUS TEST; MOUSE; MUTAGENESIS; NONHUMAN; OSTEOSARCOMA; POLYMERASE CHAIN REACTION; SOLID TUMOR; TRANSPOSON; TUMOR SUPPRESSOR GENE; UNDIFFERENTIATED CARCINOMA;

MUS;

EID: 84860359262     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-11-29     Document Type: Article

References (31)

1. Kuramochi M, Fukuhara H, Nobukuni T, Kanbe T, Maruyama T, Ghosh HP, Pletcher M, Isomura M, Onizuka M, Kitamura T, Sekiya T, Reeves RH, Murakami Y. TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer. Nat Genet 2001, 27:427-430. 10.1038/86934, 11279526.
2. Murakami Y. Involvement of a cell adhesion molecule. TSLC1/IGSF4, in human oncogenesis. Cancer Sci 2005, 96:543-552. 10.1111/j.1349-7006.2005.00089.x, 16128739.
3. Liang QL, Chen GQ, Li ZY, Wang BR. Function and histopathology of a cell adhesion molecule TSLC1 in cancer. Cancer Invest 2011, 29:107-112. 10.3109/07357907.2010.543211, 21329006.
4. Mao X, Seidlitz E, Truant R, Hitt M, Ghosh HP. Re-expression of TSLC1 in a non-small-cell lung cancer cell line induces apoptosis and inhibits tumor growth. Oncogene 2004, 23:5632-5642. 10.1038/sj.onc.1207756, 15184878.
5. Lung HL, Cheung AK, Xie D, Cheng Y, Kwong FM, Murakami Y, Guan XY, Sham JS, Chua D, Protopopov AI, Zabarovsky ER, Tsao SW, Stanbridge EJ, Lung ML. TSLC1 is a tumor suppressor gene associated with metastasis in nasopharyngeal carcinoma. Cancer Res 2006, 66:9385-9392. 10.1158/0008-5472.CAN-06-0590, 17018592.
6. van der Weyden L, Arends MJ, Chausiaux OE, Ellis PJ, Lange UC, Surani MA, Affara N, Murakami Y, Adams DJ, Bradley A. Loss of TSLC1 causes male infertility due to a defect at the spermatid stage of spermatogenesis. Mol Cell Biol 2006, 26:3595-3609. 10.1128/MCB.26.9.3595-3609.2006, 1447413, 16611999.
7. Takayanagi Y, Fujita E, Yu Z, Yamagata T, Momoi MY, Momoi T, Onaka T. Impairment of social and emotional behaviors in Cadm1-knockout mice. Biochem Biophys Res Commun 2010, 396:703-708. 10.1016/j.bbrc.2010.04.165, 20450890.
8. De Maria A, Shi Y, Luo X, Van Der Weyden L, Bassnett S. Cadm1 expression and function in the mouse lens. Invest Ophthalmol Vis Sci 2011, 52:2293-2299. 10.1167/iovs.10-6677, 3080734, 21217103.
9. Giangreco A, Jensen KB, Takai Y, Miyoshi J, Watt FM. Necl2 regulates epidermal adhesion and wound repair. Development 2009, 136:3505-3514. 10.1242/dev.038232, 2752399, 19783739.
10. Paulsson K, An Q, Moorman AV, Parker H, Molloy G, Davies T, Griffiths M, Ross FM, Irving J, Harrison CJ, Young BD, Strefford JC. Methylation of tumour suppressor gene promoters in the presence and absence of transcriptional silencing in high hyperdiploid acute lymphoblastic leukaemia. Br J Haematol 2009, 144:838-847. 10.1111/j.1365-2141.2008.07523.x, 19120349.
11. Fu L, Gao Z, Zhang X, Tsang YH, Goh HK, Geng H, Shimizu N, Tsuchiyama J, Srivastava G, Tao Q. Frequent concomitant epigenetic silencing of the stress-responsive tumor suppressor gene CADM1, and its interacting partner DAL-1 in nasal NK/T-cell lymphoma. Int J Cancer 2009, 124:1572-1578. 10.1002/ijc.24123, 19115211.
12. Heddle JA. A rapid in vivo test for chromosomal damage. Mutat Res 1973, 18:187-190. 10.1016/0027-5107(73)90035-3, 4351282.
13. Collier LS, Carlson CM, Ravimohan S, Dupuy AJ, Largaespada DA. Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse. Nature 2005, 436:272-276. 10.1038/nature03681, 16015333.
14. March HN, Rust AG, Wright NA, ten Hoeve J, de Ridder J, Eldridge M, van der Weyden L, Berns A, Gadiot J, Uren A, Kemp R, Arends MJ, Wessels LF, Winton DJ, Adams DJ. Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis. Nat Genet 2011, 43:1202-1209. 10.1038/ng.990, 3233530, 22057237.
15. Lind GE, Kleivi K, Meling GI, Teixeira MR, Thiis-Evensen E, Rognum TO, Lothe RA. ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis. Cell Oncol 2006, 28:259-272.
16. Kuster L, Grausenburger R, Fuka G, Kaindl U, Krapf G, Inthal A, Mann G, Kauer M, Rainer J, Kofler R, Hall A, Metzler M, Meyer LH, Meyer C, Harbott J, Marschalek R, Strehl S, Haas OA, Panzer-Grümayer R. ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling. Blood 2011, 117:2658-2667. 10.1182/blood-2010-03-275347, 21224468.
17. Wang LB, Zheng S, Zhang SZ, Peng JP, Ye F, Fang SC, Wu JM. Expression of ST13 in colorectal cancer and adjacent normal tissues. World J Gastroenterol 2005, 11:336-339.
18. Davidson B, Reich R, Goldberg I, Gotlieb WH, Kopolovic J, Berner A, Ben-Baruch G, Bryne M, Nesland JM. Ets-1 messenger RNA expression is a novel marker of poor survival in ovarian carcinoma. Clin Cancer Res 2001, 7:551-557.
19. Dror Y, Ward AC, Touw IP, Freedman MH. Combined corticosteroid/granulocyte colony-stimulating factor (G-CSF) therapy in the treatment of severe congenital neutropenia unresponsive to G-CSF: Activated glucocorticoid receptors synergize with G-CSF signals. Exp Hematol 2000, 28:1381-1389. 10.1016/S0301-472X(00)00544-0, 11146160.
20. Dusek RL, Attardi LD. Desmosomes: new perpetrators in tumour suppression. Nat Rev Cancer 2011, 11:317-323. 10.1038/nrc3051, 21508970.
21. Ohno H, Hirabayashi S, Kansaku A, Yao I, Tajima M, Nishimura W, Ohnishi H, Mashima H, Fujita T, Omata M, Hata Y. Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains. Oncogene 2003, 22:8422-8431. 10.1038/sj.onc.1206996, 14627983.
22. Biederer T, Sara Y, Mozhayeva M, Atasoy D, Liu X, Kavalali ET, Südhof TC. SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science 2002, 297:1525-1531. 10.1126/science.1072356, 12202822.
23. Desai BV, Harmon RM, Green KJ. Desmosomes at a glance. J Cell Sci 2009, 122:4401-4407. 10.1242/jcs.037457, 2787455, 19955337.
24. Luque-García JL, Martínez-Torrecuadrada JL, Epifano C, Cañamero M, Babel I, Casal JI. Differential protein expression on the cell surface of colorectal cancer cells associated to tumor metastasis. Proteomics 2010, 10:940-952.
25. van der Weyden L, Rust AG, McIntyre RE, Robles-Espinoza CD, Del Castillo Velasco-Herrera M, Strogantsev R, Ferguson-Smith AC, McCarthy S, Keane TM, Arends MJ, Adams DJ. Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity. Oncogene 2012, Epub ahead of print.
26. Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA. Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature 2005, 436:2212226.
27. Skrzypczak M, Gorycam K, Rubet T, Paziewska A, Mikula A, Jarosz D, Pachlewski J, Oledzki J, Ostrowski J. Modelling oncogenic signalling in colon tumors by multidirectional analyses of microarry data directed for maximization of analytical reliabilty. PLoS One 2010, 5i:e13091.
28. Su H, Hu N, Yang HH, Wang C, Takikita M, Wang QH, Giffen C, Clifford R, Hewitt SM, Shou JZ, Goldstein AM, Lee MP, Taylor PR. Global gane expression profiling and validation in esophageal squamous cell carcinoma and wiht clinical phenotypes. Clin Cancer Res 2011, 17:2955-2966. 10.1158/1078-0432.CCR-10-2724, 3086948, 21385931.
29. Landi MT, Dracheva T, Rotunno MC, Figueroa JD, Liu H, Dasgupta A, Mnn FE, Fukuoka J, Hames M, Bergen AW, Murphy SE, Pesatori AC YP, Consonni D, Bertazzi PA, Wacholder S, Shih JH, Caporaso NE, Jen J. Gene expression signature of cigarette smoking and its role in long adenocarcinoma devalopment and survival. PLoS One 2008, 3:e1651. 10.1371/journal.pone.0001651, 2249927, 18297132.
30. Buchholz M, Braun M, Heidenblut A, Kertler HA, Klōppel G, Schmiegel W, Hahn SA, Luttges J, Gress TM. Transcipthelial neoplastic lesion. Oncogene 2005, 24:6626-6636. 10.1038/sj.onc.1208804, 16103885.
31. Shedden K, Taylor JM, Enkemann SA, Tsao MS, Yeatman TJ, Gerald WL, Eschrich S, Jurisica I, Goirdana TJ, Misek DE, Chang AC, Zhu CQ, Strumpt D, Hanash S, Shepherd FA, Ding K, Seymour L, Naoki, Pennell N, Wier B, Kris M, Viale A, Motoi N, Travis W, Conley B, Seshan VE, Meyerson M, Kuick R, Dubbin KK, Lively T, Jacobson JW, Beer DG, . Directors Challenge Consortium for the Molecular Classification of Lung Adenocarcinoma Gene expression based survival prediction in lung adenocarcinoma: a multi-site blinded validation study. Nat Med 2008, 14:822-827. 10.1038/nm.1790, 2667337, 18641660, Directors Challenge Consortium for the Molecular Classification of Lung Adenocarcinoma.