Microemulsion-based patch for transdermal delivery of huperzine A and ligustrazine phosphate in treatment of Alzheimer's disease

Drug Development and Industrial Pharmacy

Volumn 38, Issue 6, 2012, Pages 752-761

  Shi, Jun ^a,b   Cong, Wenjuan ^c   Wang, Yiming ^b   Liu, Qingfei ^d   Luo, Guoan ^a,b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b TSINGHUA UNIVERSITY   (China)

^c SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d Tsinghua University   (China)

Author keywords

Coadministration; Huperzine A; Ligustrazine phosphate; Microemulsion; Pharmacodynamics; Transdermal delivery

Indexed keywords

ALCOHOL; CINEOLE; CREMOPHOR; HUPERZINE A; MACROGOL 400; OLEIC ACID; POLYVINYL ALCOHOL; POVIDONE; SORBITOL; TETRAMETHYLPYRAZINE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG PENETRATION; FEASIBILITY STUDY; IN VITRO STUDY; KINETICS; MALE; MICROEMULSION; MONOTHERAPY; NONHUMAN; PROCEDURES; RAT; TRANSDERMAL PATCH;

ADMINISTRATION, CUTANEOUS; ALKALOIDS; ALZHEIMER DISEASE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; DRUG THERAPY, COMBINATION; EMULSIONS; MALE; NEUROPROTECTIVE AGENTS; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; SESQUITERPENES; SKIN ABSORPTION; TIME FACTORS; TRANSDERMAL PATCH; VASODILATOR AGENTS;

EID: 84860358563     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2011.625031     Document Type: Article

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