Different matrix attachment regions flanking a transgene effectively enhance gene expression in stably transfected Chinese hamster ovary cells

Gene

Volumn 500, Issue 1, 2012, Pages 59-62

  Wang, Fang ^a   Wang, Tian Yun ^a   Tang, Yuan Yuan ^a   Zhang, Jun He ^a   Yang, Xian Jun ^a  

^a XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

Gene silencing; Mammalian expression system; Matrix attachment region; Transgene copy number

Indexed keywords

BETA GLOBIN; BETA INTERFERON; CHLORAMPHENICOL ACETYLTRANSFERASE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHO CELL; COPY NUMBER VARIATION; FEMALE; GENE EXPRESSION; MATRIX ATTACHMENT REGION; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENE;

ANIMALS; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CHO CELLS; CRICETINAE; GENE DOSAGE; GENES, REPORTER; INTERFERON-BETA; MATRIX ATTACHMENT REGIONS; TRANSFECTION; TRANSGENES;

CRICETULUS GRISEUS; MAMMALIA;

EID: 84860340646     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2012.03.049     Document Type: Article

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