Cellular interactions of synovial fluid γδ T cells in juvenile idiopathic arthritis

Journal of Immunology

Volumn 188, Issue 9, 2012, Pages 4349-4359

  Bendersky, Anna ^a   Marcu Malina, Victoria ^a   Berkun, Yackov ^a   Gerstein, Maya ^a   Nagar, Meital ^a   Goldstein, Itamar ^a   Padeh, Shai ^a   Bank, Ilan ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CD69 ANTIGEN; GAMMA INTERFERON; ISOPENTENYL DIPHOSPHATE; MEVALONIC ACID; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; ZOLEDRONIC ACID;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL INTERACTION; CELLULAR DISTRIBUTION; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG POTENCY; DRUG TARGETING; FIBROBLAST; FIBROBLAST CULTURE; GAMMA DELTA T LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; JUVENILE RHEUMATOID ARTHRITIS; LYMPHOCYTE DEPLETION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; METABOLITE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SYNOVIAL FLUID; T LYMPHOCYTE SUBPOPULATION; UPREGULATION;

ADULT; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ARTHRITIS, JUVENILE RHEUMATOID; BONE DENSITY CONSERVATION AGENTS; CELL COMMUNICATION; CELL PROLIFERATION; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; COCULTURE TECHNIQUES; DIPHOSPHONATES; FEMALE; FIBROBLASTS; GERANYLTRANSTRANSFERASE; HEMITERPENES; HUMANS; IMIDAZOLES; INTERFERON-GAMMA; LECTINS, C-TYPE; MALE; ORGANOPHOSPHORUS COMPOUNDS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SYNOVIAL FLUID; T-LYMPHOCYTES, REGULATORY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84860328810     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102403     Document Type: Article

References (28)

1. Bank, I., R. A. DePinho, M. B. Brenner, J. Cassimeris, F. W. Alt, and L. Chess. 1986. A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes. Nature 322: 179-181. (Pubitemid 16005457)
2. Brenner, M. B., J. McLean, D. P. Dialynas, J. L. Strominger, J. A. Smith, F. L. Owen, J. G. Seidman, S. Ip, F. Rosen, and M. S. Krangel. 1986. Identification of a putative second T-cell receptor. Nature 322: 145-149. (Pubitemid 16005451)
3. Morita, C. T., E. M. Beckman, J. F. Bukowski, Y. Tanaka, H. Band, B. R. Bloom, D. E. Golan, and M. B. Brenner. 1995. Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells. Immunity 3: 495-507.
4. Hayday, A. C. 2000. [gamma][delta] cells: a right time and a right place for a conserved third way of protection. Annu. Rev. Immunol. 18: 975-1026. (Pubitemid 30365402)
5. Kabelitz, D., A. Glatzel, and D. Wesch. 2000. Antigen recognition by human gammadelta T lymphocytes. Int. Arch. Allergy Immunol. 122: 1-7. (Pubitemid 30307425)
6. Hintz, M., A. Reichenberg, B. Altincicek, U. Bahr, R. M. Gschwind, A. K. Kollas, E. Beck, J. Wiesner, M. Eberl, and H. Jomaa. 2001. Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gammadelta T cells in Escherichia coli. FEBS Lett. 509: 317-322. (Pubitemid 34015963)
7. Mookerjee-Basu, J., P. Vantourout, L. O. Martinez, B. Perret, X. Collet, C. Périgaud, S. Peyrottes, and E. Champagne. 2010. F1-adenosine triphosphatase displays properties characteristic of an antigen presentation molecule for Vgamma9Vdelta2 T cells. J. Immunol. 184: 6920-6928.
8. Nagashima, T., H. Okazaki, K. Yudoh, H. Matsuno, and S. Minota. 2006. Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis. Arthritis Rheum. 54: 579-586. (Pubitemid 43228634)
9. Houten, S. M., J. Frenkel, and H. R. Waterham. 2003. Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation. Cell. Mol. Life Sci. 60: 1118-1134. (Pubitemid 36791916)
10. Ravelli, A., and A. Martini. 2007. Juvenile idiopathic arthritis. Lancet 369: 767-778.
11. Brewer, E. J., Jr., J. Bass, J. Baum, J. T. Cassidy, C. Fink, J. Jacobs, V. Hanson, J. E. Levinson, J. Schaller, and J. S. Stillman; JRA Criteria Subcommittee of the Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Section of The Arthritis Foundation. 1977. Current proposed revision of JRA Criteria. Arthritis Rheum. 20(Suppl 2): 195-199.
12. Prakken, B., S. Albani, and A. Martini. 2011. Juvenile idiopathic arthritis. Lancet 377: 2138-2149.
13. Berkun, Y., A. Bendersky, M. Gerstein, I. Goldstein, S. Padeh, and I. Bank. 2011. GammadeltaT cells in juvenile idiopathic arthritis: higher percentages of synovial Vdelta1+ and Vgamma9+ T cell subsets are associated with milder disease. J. Rheumatol. 38: 1123-1129.
14. Olive, C., P. A. Gatenby, and S. W. Serjeantson. 1992. Molecular characterization of the V gamma 9 T cell receptor repertoire expressed in patients with rheumatoid arthritis. Eur. J. Immunol. 22: 2901-2906.
15. Bendersky, A., N. Markovits, and I. Bank. 2010. Vgamma9+ gammadelta T cells in systemic sclerosis patients are numerically and functionally preserved and induce fibroblast apoptosis. Immunobiology 215: 380-394.
16. Goldstein, I., S. Ben-Horin, J. Li, I. Bank, H. Jiang, and L. Chess. 2003. Expression of the alpha1beta1 integrin, VLA-1, marks a distinct subset of human CD4+ memory T cells. J. Clin. Invest. 112: 1444-1454. (Pubitemid 38057698)
17. Gruenbacher, G., H. Gander, A. Rahm, W. Nussbaumer, N. Romani, and M. Thurnher. 2009. CD56+ human blood dendritic cells effectively promote TH1-type gammadelta T-cell responses. Blood 114: 4422-4431.
18. Roelofs, A. J., M. Jauhiainen, H. Mönkkönen, M. J. Rogers, J. Mönkkönen, and K. Thompson. 2009. Peripheral blood monocytes are responsible for gamma-delta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP. Br. J. Haematol. 144: 245-250.
19. Bartok, B., and G. S. Firestein. 2010. Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunol. Rev. 233: 233-255.
20. Kiener, H. P., B. Niederreiter, D. M. Lee, E. Jimenez-Boj, J. S. Smolen, and M. B. Brenner. 2009. Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes. Arthritis Rheum. 60: 1305-1310.
21. de Kleer, I. M., L. R. Wedderburn, L. S. Taams, A. Patel, H. Varsani, M. Klein, W. de Jager, G. Pugayung, F. Giannoni, G. Rijkers, et al. 2004. CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis. J. Immunol. 172: 6435-6443. (Pubitemid 38621253)
22. Nagar, M., J. Jacob-Hirsch, H. Vernitsky, Y. Berkun, S. Ben-Horin, N. Amariglio, I. Bank, Y. Kloog, G. Rechavi, and I. Goldstein. 2010. TNF activates a NF-kappaB-regulated cellular program in human CD45RA- regulatory T cells that modulates their suppressive function. J. Immunol. 184: 3570-3581.
23. Feldmann, M., and R. N. Maini. 2010. Anti-TNF therapy, from rationale to standard of care: what lessons has it taught us? J. Immunol. 185: 791-794.
24. Hu, X., and L. B. Ivashkiv. 2009. Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases. Immunity 31: 539-550.
25. Cua, D. J., and C. M. Tato. 2010. Innate IL-17-producing cells: the sentinels of the immune system. Nat. Rev. Immunol. 10: 479-489.
26. Morita, C. T., H. K. Lee, D. S. Leslie, Y. Tanaka, J. F. Bukowski, and E. Marker-Hermann. 1999. Recognition of nonpeptide prenyl pyrophosphate antigens by human gammadelta T cells. Microbes Infect. 1: 175-186.
27. Macaubas, C., K. Nguyen, C. Deshpande, C. Phillips, A. Peck, T. Lee, J. L. Park, C. Sandborg, and E. D. Mellins. 2010. Distribution of circulating cells in systemic juvenile idiopathic arthritis across disease activity states. Clin. Immunol. 134: 206-216.
28. Wang, I. K., S. Y. Lin-Shiau, and J. K. Lin. 2000. Suppression of invasion and MMP-9 expression in NIH 3T3 and v-H-Ras 3T3 fibroblasts by lovastatin through inhibition of ras isoprenylation. Oncology 59: 245-254.