Suppression of invasion and MMP-9 expression in NIH 3T3 and v-H-Ras 3T3 fibroblasts by lovastatin through inhibition of Ras isoprenylation

Oncology

Volumn 59, Issue 3, 2000, Pages 245-254

  Wang, Ing Kae ^a   Lin Shiau, Shoei Yn ^a   Lin, Jen Kun ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

AP 1; Invasion; Isoprenylation; Lovastatin; Matrix metalloproteinase; NF B; Ras

Indexed keywords

CHOLESTEROL; GELATINASE B; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MANUMYCIN; MEVALONIC ACID; MEVINOLIN; PROTEIN FARNESYLTRANSFERASE INHIBITOR; RAS PROTEIN; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CELL INVASION; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FIBROBLAST CULTURE; IN VITRO STUDY; ISOPRENYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 0033758875     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000012168     Document Type: Article

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