Epidemiology of gallbladder disease: Cholelithiasis and cancer

Gut and Liver

Volumn 6, Issue 2, 2012, Pages 172-187

  Stinton, Laura M ^a   Shaffer, Eldon A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Cholecystectomy; Gallbladder cancer; Gallbladder polyps; Gallstones

Indexed keywords

CHOLELITHIASIS; CROHN DISEASE; ETHNICITY; GALLBLADDER CANCER; GALLBLADDER DISEASE; GENDER; HEMOLYSIS; HUMAN; INCIDENCE; LIVER CIRRHOSIS; METABOLIC SYNDROME X; OBESITY; REVIEW; RISK FACTOR;

EID: 84860328439     PISSN: 19762283     EISSN: None     Source Type: Journal    
DOI: 10.5009/gnl.2012.6.2.172     Document Type: Review

References (226)

1. Gracie WA, Ransohoff DF. The natural history of silent gallstones: The innocent gallstone is not a myth. N Engl J Med 1982;307:798-800. (Pubitemid 12061552)
2. Shaffer EA. Epidemiology and risk factors for gallstone disease: Has the paradigm changed in the 21st century? Curr Gastroenterol Rep 2005;7:132-140. (Pubitemid 40796699)
3. Kratzer W, Mason RA, Kächele V. Prevalence of gallstones in sonographic surveys worldwide. J Clin Ultrasound 1999;27:1-7. (Pubitemid 28565294)
4. Pedersen G, Hoem D, Andrén-Sandberg A. Influence of laparoscopic cholecystectomy on the prevalence of operations for gallstones in Norway. Eur J Surg 2002;168:464-469. (Pubitemid 36020888)
5. Schirmer BD, Winters KL, Edlich RF. Cholelithiasis and cholecystitis. J Long Term Eff Med Implants 2005;15:329-338. (Pubitemid 40826606)
6. Everhart JE, Khare M, Hill M, Maurer KR. Prevalence and ethnic differences in gallbladder disease in the United States. Gastroenterology 1999;117:632-639. (Pubitemid 29409249)
7. Tazuma S. Gallstone disease: Epidemiology, pathogenesis, and classification of biliary stones (common bile duct and intrahepatic). Best Pract Res Clin Gastroenterol 2006;20:1075-1083. (Pubitemid 44774809)
8. Sandler RS, Everhart JE, Donowitz M, et al. The burden of selected digestive diseases in the United States. Gastroenterology 2002;122:1500-1511. (Pubitemid 34465190)
9. Everhart JE, Ruhl CE. Burden of digestive diseases in the United States part I: Overall and upper gastrointestinal diseases. Gastroenterology 2009;136:376-386.
10. Shaheen NJ, Hansen RA, Morgan DR, et al. The burden of gastrointestinal and liver diseases, 2006. Am J Gastroenterol 2006;101:2128-2138. (Pubitemid 44337640)
11. Ruhl CE, Everhart JE. Gallstone disease is associated with increased mortality in the United States. Gastroenterology 2011;140:508-516.
12. Grimaldi CH, Nelson RG, Pettitt DJ, Sampliner RE, Bennett PH, Knowler WC. Increased mortality with gallstone disease: Results of a 20-year population-based survey in Pima Indians. Ann Intern Med 1993;118:185-190. (Pubitemid 23034803)
13. Lindkvist B, Appelros S, Manjer J, Borgström A. Trends in incidence of acute pancreatitis in a Swedish population: Is there really an increase? Clin Gastroenterol Hepatol 2004;2:831-837. (Pubitemid 39200723)
14. Legorreta AP, Silber JH, Costantino GN, Kobylinski RW, Zatz SL. Increased cholecystectomy rate after the introduction of laparoscopic cholecystectomy. JAMA 1993;270:1429-1432. (Pubitemid 23273749)
15. Marshall D, Clark E, Hailey D. The impact of laparoscopic cholecystectomy in Canada and Australia. Health Policy 1994;26:221-230. (Pubitemid 24087607)
16. Kang JY, Ellis C, Majeed A, et al. Gallstones: An increasing problem: A study of hospital admissions in England between 1989/1990 and 1999/2000. Aliment Pharmacol Ther 2003;17:561-569. (Pubitemid 36384815)
17. Nenner RP, Imperato PJ, Rosenberg C, Ronberg E. Increased cholecystectomy rates among Medicare patients after the introduction of laparoscopic cholecystectomy. J Community Health 1994;19:409-415. (Pubitemid 24348264)
18. Russo MW, Wei JT, Thiny MT, et al. Digestive and liver diseases statistics, 2004. Gastroenterology 2004;126:1448-1453. (Pubitemid 38552807)
19. Zacks SL, Sandler RS, Rutledge R, Brown RS Jr. A populationbased cohort study comparing laparoscopic cholecystectomy and open cholecystectomy. Am J Gastroenterol 2002;97:334-340. (Pubitemid 34160758)
20. Gibney EJ. Asymptomatic gallstones. Br J Surg 1990;77:368-372. (Pubitemid 20119367)
21. Sakorafas GH, Milingos D, Peros G. Asymptomatic cholelithiasis: Is cholecystectomy really needed? A critical reappraisal 15 years after the introduction of laparoscopic cholecystectomy. Dig Dis Sci 2007;52:1313-1325. (Pubitemid 46626157)
22. Halldestam I, Enell EL, Kullman E, Borch K. Development of symptoms and complications in individuals with asymptomatic gallstones. Br J Surg 2004;91:734-738. (Pubitemid 38746142)
23. Thistle JL, Cleary PA, Lachin JM, Tyor MP, Hersh T. The natural history of cholelithiasis: The National Cooperative Gallstone Study. Ann Intern Med 1984;101:171-175. (Pubitemid 14098321)
24. Ransohoff DF, Gracie WA, Wolfenson LB, Neuhauser D. Prophylactic cholecystectomy or expectant management for silent gallstones. A decision analysis to assess survival. Ann Intern Med 1983;99:199-204. (Pubitemid 13041472)
25. Friedman GD. Natural history of asymptomatic and symptomatic gallstones. Am J Surg 1993;165:399-404. (Pubitemid 23276818)
26. Schirmer BD, Winters KL, Edlich RF. Cholelithiasis and cholecystitis. J Long Term Eff Med Implants 2005;15:329-338. (Pubitemid 40826606)
27. Kapoor VK. Cholecystectomy in patients with asymptomatic gallstones to prevent gall bladder cancer: The case against. Indian J Gastroenterol 2006;25:152-154. (Pubitemid 44326055)
28. Bonatsos G, Birbas K, Toutouzas K, Durakis N. Laparoscopic cholecystectomy in adults with sickle cell disease. Surg Endosc 2001;15:816-819. (Pubitemid 32702371)
29. Ebert EC, Nagar M, Hagspiel KD. Gastrointestinal and hepatic complications of sickle cell disease. Clin Gastroenterol Hepatol 2010;8:483-489.
30. Kao LS, Kuhr CS, Flum DR. Should cholecystectomy be performed for asymptomatic cholelithiasis in transplant patients? J Am Coll Surg 2003;197:302-312. (Pubitemid 36927394)
31. Shiffman ML, Sugerman HJ, Kellum JM, Brewer WH, Moore EW. Gallstone formation after rapid weight loss: A prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity. Am J Gastroenterol 1991;86:1000-1005.
32. Jørgensen T. Abdominal symptoms and gallstone disease: An epidemiological investigation. Hepatology 1989;9:856-860. (Pubitemid 19140091)
33. Traverso LW. Clinical manifestations and impact of gallstone disease. Am J Surg 1993;165:405-409. (Pubitemid 23276819)
34. Fenster LF, Lonborg R, Thirlby RC, Traverso LW. What symptoms does cholecystectomy cure? Insights from an outcomes measurement project and review of the literature. Am J Surg 1995;169:533-538.
35. Festi D, Sottili S, Colecchia A, et al. Clinical manifestations of gallstone disease: Evidence from the multicenter Italian study on cholelithiasis (MICOL). Hepatology 1999;30:839-846. (Pubitemid 29458268)
36. Berhane T, Vetrhus M, Hausken T, Olafsson S, Søndenaa K. Pain attacks in non-complicated and complicated gallstone disease have a characteristic pattern and are accompanied by dyspepsia in most patients: The results of a prospective study. Scand J Gastroenterol 2006;41:93-101. (Pubitemid 43030897)
37. Weinert CR, Arnett D, Jacobs D Jr, Kane RL. Relationship between persistence of abdominal symptoms and successful outcome after cholecystectomy. Arch Intern Med 2000;160:989-995. (Pubitemid 30191928)
38. Vetrhus M, Berhane T, Søreide O, Søndenaa K. Pain persists in many patients five years after removal of the gallbladder: Observations from two randomized controlled trials of symptomatic, noncomplicated gallstone disease and acute cholecystitis. J Gastrointest Surg 2005;9:826-831. (Pubitemid 40883980)
39. Mertens MC, Roukema JA, Scholtes VP, De Vries J. Risk assessment in cholelithiasis: Is cholecystectomy always to be preferred? J Gastrointest Surg 2010;14:1271-1279.
40. Thistle JL, Longstreth GF, Romero Y, et al. Factors that predict relief from upper abdominal pain after cholecystectomy. Clin Gastroenterol Hepatol 2011;9:891-896.
41. Shaffer E. Acalculous biliary pain: New concepts for an old entity. Dig Liver Dis 2003;35 Suppl 3:S20-S25. (Pubitemid 41070425)
42. DiBaise JK, Richmond BK, Ziessman HH, et al. Cholecystokinincholescintigraphy in adults: Consensus recommendations of an interdisciplinary panel. Clin Gastroenterol Hepatol 2011;9:376-384.
43. Gurusamy KS, Junnarkar S, Farouk M, Davidson BR. Cholecystectomy for suspected gallbladder dyskinesia. Cochrane Database Syst Rev 2009;(1):CD007086.
44. Shaffer EA. Gallstone disease: Epidemiology of gallbladder stone disease. Best Pract Res Clin Gastroenterol 2006;20:981-996. (Pubitemid 44793722)
45. Everhart JE, Yeh F, Lee ET, et al. Prevalence of gallbladder disease in American Indian populations: Findings from the Strong Heart Study. Hepatology 2002;35:1507-1512. (Pubitemid 34966906)
46. Miquel JF, Covarrubias C, Villaroel L, et al. Genetic epidemiology of cholesterol cholelithiasis among Chilean Hispanics, Amerindians, and Maoris. Gastroenterology 1998;115:937-946. (Pubitemid 28452942)
47. Everhart JE. Gallstones and ethnicity in the Americas. J Assoc Acad Minor Phys 2001;12:137-143.
48. Diehl AK, Stern MP. Special health problems of Mexican-Americans: Obesity, gallbladder disease, diabetes mellitus, and cardiovascular disease. Adv Intern Med 1989;34:73-96.
49. Maurer KR, Everhart JE, Ezzati TM, et al. Prevalence of gallstone disease in Hispanic populations in the United States. Gastroenterology 1989;96(2 Pt 1):487-492. (Pubitemid 19045282)
50. Hanis CL, Hewett-Emmett D, Kubrusly LF, et al. An ultrasound survey of gallbladder disease among Mexican Americans in Starr County, Texas: Frequencies and risk factors. Ethn Dis 1993;3:32-43.
51. Singh V, Trikha B, Nain C, Singh K, Bose S. Epidemiology of gallstone disease in Chandigarh: A community-based study. J Gastroenterol Hepatol 2001;16:560-563. (Pubitemid 34188865)
52. Chen CY, Lu CL, Huang YS, et al. Age is one of the risk factors in developing gallstone disease in Taiwan. Age Ageing 1998;27:437-441.
53. Bagi Abdel M, Arabi M, Abdel Rahim B, et al. Prevalence of gallbladder disease in Sudan: First sonographic field study in adult population. Gastroenterology 1991;100:A307.
54. Shoda J, Tanaka N, Osuga T. Hepatolithiasis: Epidemiology and pathogenesis update. Front Biosci 2003;8:e398-e409.
55. Lammert F, Matern S. The genetic background of cholesterol gallstone formation: An inventory of human lithogenic genes. Curr Drug Targets Immune Endocr Metabol Disord 2005;5:163-170. (Pubitemid 40766860)
56. Sarin SK, Negi VS, Dewan R, Sasan S, Saraya A. High familial prevalence of gallstones in the first-degree relatives of gallstone patients. Hepatology 1995;22:138-141.
57. Gilat T, Feldman C, Halpern Z, Dan M, Bar-Meir S. An increased familial frequency of gallstones. Gastroenterology 1983;84:242-246. (Pubitemid 13224261)
58. van der Linden W, Westlin N. The familial occurrence of gallstone disease. II. Occurrence in husbands and wives. Acta Genet Stat Med 1966;16:377-382.
59. Katsika D, Grjibovski A, Einarsson C, Lammert F, Lichtenstein P, Marschall HU. Genetic and environmental influences on symptomatic gallstone disease: A Swedish study of 43,141 twin pairs. Hepatology 2005;41:1138-1143. (Pubitemid 40593922)
60. Rudkowska I, Jones PJ. Polymorphisms in ABCG5/G8 transporters linked to hypercholesterolemia and gallstone disease. Nutr Rev 2008;66:343-348. (Pubitemid 351792520)
61. Stinton LM, Myers RP, Shaffer EA. Epidemiology of gallstones. Gastroenterol Clin North Am 2010;39:157-169.
62. Mittal B, Mittal RD. Genetics of gallstone disease. J Postgrad Med 2002;48:149-152. (Pubitemid 35012376)
63. Pullinger CR, Eng C, Salen G, et al. Human cholesterol 7alphahydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. J Clin Invest 2002;110:109-117. (Pubitemid 34743471)
64. Schneider H, Sänger P, Hanisch E. In vitro effects of cholecystokinin fragments on human gallbladders. Evidence for an altered CCK-receptor structure in a subgroup of patients with gallstones. J Hepatol 1997;26:1063-1068. (Pubitemid 27242596)
65. Feng D, Han T, Chen S. Polymorphism at the LDL receptor gene locus in patients with cholesterol gallstone disease. Zhonghua Yi Xue Za Zhi 1998;78:63-65.
66. Juvonen T, Savolainen MJ, Kairaluoma MI, Lajunen LH, Humphries SE, Kesäniemi YA. Polymorphisms at the apoB, apoAI, and cholesteryl ester transfer protein gene loci in patients with gallbladder disease. J Lipid Res 1995;36:804-812.
67. Buch S, Schafmayer C, Völzke H, et al. A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease. Nat Genet 2007;39:995-999. (Pubitemid 47185186)
68. Grünhage F, Acalovschi M, Tirziu S, et al. Increased gallstone risk in humans conferred by common variant of hepatic ATP-binding cassette transporter for cholesterol. Hepatology 2007;46:793-801. (Pubitemid 47436126)
69. Einarsson K, Nilsell K, Leijd B, Angelin B. Influence of age on secretion of cholesterol and synthesis of bile acids by the liver. N Engl J Med 1985;313:277-282. (Pubitemid 15044228)
70. Völzke H, Baumeister SE, Alte D, et al. Independent risk factors for gallstone formation in a region with high cholelithiasis prevalence. Digestion 2005;71:97-105. (Pubitemid 40674577)
71. Cirillo DJ, Wallace RB, Rodabough RJ, et al. Effect of estrogen therapy on gallbladder disease. JAMA 2005;293:330-339. (Pubitemid 40116088)
72. Thijs C, Knipschild P. Oral contraceptives and the risk of gallbladder disease: A meta-analysis. Am J Public Health 1993;83:1113-1120. (Pubitemid 23229114)
73. Hulley S, Grady D, Bush T, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA 1998;280:605-613. (Pubitemid 28502636)
74. Etminan M, Delaney JA, Bressler B, Brophy JM. Oral contraceptives and the risk of gallbladder disease: A comparative safety study. CMAJ 2011;183:899-904.
75. Maringhini A, Ciambra M, Baccelliere P, et al. Biliary sludge and gallstones in pregnancy: Incidence, risk factors, and natural history. Ann Intern Med 1993;119:116-120. (Pubitemid 23286476)
76. Valdivieso V, Covarrubias C, Siegel F, Cruz F. Pregnancy and cholelithiasis: Pathogenesis and natural course of gallstones diagnosed in early puerperium. Hepatology 1993;17:1-4. (Pubitemid 23027375)
77. Ko CW, Beresford SA, Schulte SJ, Lee SP. Insulin resistance and incident gallbladder disease in pregnancy. Clin Gastroenterol Hepatol 2008;6:76-81. (Pubitemid 50008420)
78. Ogden CL, Yanovski SZ, Carroll MD, Flegal KM. The epidemiology of obesity. Gastroenterology 2007;132:2087-2102. (Pubitemid 46693751)
79. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 2006;295:1549-1555.
80. Erlinger S. Gallstones in obesity and weight loss. Eur J Gastroenterol Hepatol 2000;12:1347-1352. (Pubitemid 32057379)
81. Amaral JF, Thompson WR. Gallbladder disease in the morbidly obese. Am J Surg 1985;149:551-557. (Pubitemid 15050919)
82. Johansen C, Chow WH, Jørgensen T, Mellemkjaer L, Engholm G, Olsen JH. Risk of colorectal cancer and other cancers in patients with gall stones. Gut 1996;39:439-443. (Pubitemid 26338535)
83. Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Prospective study of abdominal adiposity and gallstone disease in US men. Am J Clin Nutr 2004;80:38-44. (Pubitemid 41115552)
84. Li VK, Pulido N, Fajnwaks P, Szomstein S, Rosenthal R, Martinez-Duartez P. Predictors of gallstone formation after bariatric surgery: A multivariate analysis of risk factors comparing gastric bypass, gastric banding, and sleeve gastrectomy. Surg Endosc 2009;23:1640-1644.
85. Maclure KM, Hayes KC, Colditz GA, Stampfer MJ, Speizer FE, Willett WC. Weight, diet, and the risk of symptomatic gallstones in middle-aged women. N Engl J Med 1989;321:563-569. (Pubitemid 19212867)
86. Lambou-Gianoukos S, Heller SJ. Lithogenesis and bile metabolism. Surg Clin North Am 2008;88:1175-1194.
87. Shaffer EA, Small DM. Biliary lipid secretion in cholesterol gallstone disease. The effect of cholecystectomy and obesity. J Clin Invest 1977;59:828-840. (Pubitemid 8096335)
88. Petitti DB, Friedman GD, Klatsky AL. Association of a history of gallbladder disease with a reduced concentration of high-densitylipoprotein cholesterol. N Engl J Med 1981;304:1396-1398. (Pubitemid 11073571)
89. Ahlberg J. Serum lipid levels and hyperlipoproteinaemia in gallstone patients. Acta Chir Scand 1979;145:373-377. (Pubitemid 10160957)
90. Barbara L, Sama C, Morselli Labate AM, et al. A population study on the prevalence of gallstone disease: The Sirmione Study. Hepatology 1987;7:913-917. (Pubitemid 17139241)
91. Thijs C, Knipschild P, Brombacher P. Serum lipids and gallstones: A case-control study. Gastroenterology 1990;99:843-849. (Pubitemid 20243380)
92. Sakuta H, Suzuki T. Plasma total homocysteine and gallstone in middle-aged Japanese men. J Gastroenterol 2005;40:1061-1064. (Pubitemid 43055291)
93. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285:2486-2497.
94. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet 2005;365:1415-1428. (Pubitemid 40523737)
95. Méndez-Sánchez N, Chavez-Tapia NC, Motola-Kuba D, et al. Metabolic syndrome as a risk factor for gallstone disease. World J Gastroenterol 2005;11:1653-1657. (Pubitemid 40520807)
96. Ata N, Kucukazman M, Yavuz B, et al. The metabolic syndrome is associated with complicated gallstone disease. Can J Gastroenterol 2011;25:274-276.
97. Ruhl CE, Everhart JE. Association of diabetes, serum insulin, and C-peptide with gallbladder disease. Hepatology 2000;31:299-303. (Pubitemid 30078591)
98. Nervi F, Miquel JF, Alvarez M, et al. Gallbladder disease is associated with insulin resistance in a high risk Hispanic population. J Hepatol 2006;45:299-305. (Pubitemid 44026566)
99. Biddinger SB, Haas JT, Yu BB, et al. Hepatic insulin resistance directly promotes formation of cholesterol gallstones. Nat Med 2008;14:778-782.
100. Twisk J, Hoekman MF, Lehmann EM, Meijer P, Mager WH, Princen HM. Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase gene transcription. Hepatology 1995;21:501-510.
101. Nakeeb A, Comuzzie AG, Al-Azzawi H, Sonnenberg GE, Kissebah AH, Pitt HA. Insulin resistance causes human gallbladder dysmotility. J Gastrointest Surg 2006;10:940-948.
102. Everhart JE. Contributions of obesity and weight loss to gallstone disease. Ann Intern Med 1993;119:1029-1035. (Pubitemid 23334660)
103. Yang H, Petersen GM, Roth MP, Schoenfield LJ, Marks JW. Risk factors for gallstone formation during rapid loss of weight. Dig Dis Sci 1992;37:912-918.
104. Weinsier RL, Ullmann DO. Gallstone formation and weight loss. Obes Res 1993;1:51-56.
105. Liddle RA, Goldstein RB, Saxton J. Gallstone formation during weight-reduction dieting. Arch Intern Med 1989;149:1750-1753. (Pubitemid 19200829)
106. Shiffman ML, Sugerman HJ, Kellum JM, Brewer WH, Moore EW. Gallstone formation after rapid weight loss: A prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity. Am J Gastroenterol 1991;86:1000-1005.
107. Broomfield PH, Chopra R, Sheinbaum RC, et al. Effects of ursodeoxycholic acid and aspirin on the formation of lithogenic bile and gallstones during loss of weight. N Engl J Med 1988;319:1567-1572. (Pubitemid 19003422)
108. Wudel LJ Jr, Wright JK, Debelak JP, Allos TM, Shyr Y, Chapman WC. Prevention of gallstone formation in morbidly obese patients undergoing rapid weight loss: Results of a randomized controlled pilot study. J Surg Res 2002;102:50-56.
109. Weinsier RL, Wilson LJ, Lee J. Medically safe rate of weight loss for the treatment of obesity: A guideline based on risk of gallstone formation. Am J Med 1995;98:115-117.
110. Al-Jiffry BO, Shaffer EA, Saccone GT, Downey P, Kow L, Toouli J. Changes in gallbladder motility and gallstone formation following laparoscopic gastric banding for morbid obestity. Can J Gastroenterol 2003;17:169-174. (Pubitemid 36608953)
111. Syngal S, Coakley EH, Willett WC, Byers T, Williamson DF, Colditz GA. Long-term weight patterns and risk for cholecystectomy in women. Ann Intern Med 1999;130:471-477. (Pubitemid 29135799)
112. Jørgensen T, Jørgensen LM. Gallstones and diet in a Danish population. Scand J Gastroenterol 1989;24:821-826.
113. Méndez-Sánchez N, Zamora-Valdés D, Chávez-Tapia NC, Uribe M. Role of diet in cholesterol gallstone formation. Clin Chim Acta 2007;376:1-8 (Pubitemid 44911080)
114. Cuevas A, Miquel JF, Reyes MS, Zanlungo S, Nervi F. Diet as a risk factor for cholesterol gallstone disease. J Am Coll Nutr 2004;23:187-196. (Pubitemid 38746106)
115. Tseng M, Everhart JE, Sandler RS. Dietary intake and gallbladder disease: A review. Public Health Nutr 1999;2:161-172. (Pubitemid 29314499)
116. Lee DW, Gilmore CJ, Bonorris G, et al. Effect of dietary cholesterol on biliary lipids in patients with gallstones and normal subjects. Am J Clin Nutr 1985;42:414-420. (Pubitemid 15227627)
117. Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Long-chain saturated fatty acids consumption and risk of gallstone disease among men. Ann Surg 2008;247:95-103.
118. Scragg RK, McMichael AJ, Baghurst PA. Diet, alcohol, and relative weight in gall stone disease: A case-control study. Br Med J (Clin Res Ed) 1984;288:1113-1119. (Pubitemid 14083774)
119. Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Dietary carbohydrates and glycaemic load and the incidence of symptomatic gall stone disease in men. Gut 2005;54:823-828. (Pubitemid 40732101)
120. Nervi F, Covarrubias C, Bravo P, et al. Influence of legume intake on biliary lipids and cholesterol saturation in young Chilean men. Identification of a dietary risk factor for cholesterol gallstone formation in a highly prevalent area. Gastroenterology 1989;96:825-830. (Pubitemid 19057606)
121. Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. The effect of long-term intake of cis unsaturated fats on the risk for gallstone disease in men: A prospective cohort study. Ann Intern Med 2004;141:514-522. (Pubitemid 39350241)
122. Leitzmann MF, Willett WC, Rimm EB, et al. A prospective study of coffee consumption and the risk of symptomatic gallstone disease in men. JAMA 1999;281:2106-2112. (Pubitemid 29264689)
123. Leitzmann MF, Stampfer MJ, Willett WC, Spiegelman D, Colditz GA, Giovannucci EL. Coffee intake is associated with lower risk of symptomatic gallstone disease in women. Gastroenterology 2002;123:1823-1830. (Pubitemid 35408306)
124. Leitzmann MF, Tsai CJ, Stampfer MJ, et al. Alcohol consumption in relation to risk of cholecystectomy in women. Am J Clin Nutr 2003;78:339-347. (Pubitemid 39655242)
125. Attili AF, Scafato E, Marchioli R, Marfisi RM, Festi D. Diet and gallstones in Italy: The cross-sectional MICOL results. Hepatology 1998;27:1492-1498. (Pubitemid 28264670)
126. Simon JA, Hudes ES. Serum ascorbic acid and gallbladder disease prevalence among US adults: The Third National Health and Nutrition Examination Survey (NHANES III). Arch Intern Med 2000;160:931-936. (Pubitemid 30191920)
127. Simon JA, Hudes ES. Serum ascorbic acid and other correlates of gallbladder disease among US adults. Am J Public Health 1998;88:1208-1212. (Pubitemid 28361363)
128. Leitzmann MF, Giovannucci EL, Stampfer MJ, et al. Prospective study of alcohol consumption patterns in relation to symptomatic gallstone disease in men. Alcohol Clin Exp Res 1999;23:835-841. (Pubitemid 29256570)
129. Su CH, Lui WY, P'eng FK. Relative prevalence of gallstone diseases in Taiwan. A nationwide cooperative study. Dig Dis Sci 1992;37:764-768.
130. Kameda H, Ishihara F, Shibata K, Tsukie E. Clinical and nutritional study on gallstone disease in Japan. Jpn J Med 1984;23:109-113. (Pubitemid 14049688)
131. Guglielmi FW, Boggio-Bertinet D, Federico A, et al. Total parenteral nutrition-related gastroenterological complications. Dig Liver Dis 2006;38:623-642. (Pubitemid 44356260)
132. Roslyn JJ, Pitt HA, Mann LL, Ament ME, DenBesten L. Gallbladder disease in patients on long-term parenteral nutrition. Gastroenterology 1983;84:148-154. (Pubitemid 13198302)
133. Baudet S, Medina C, Vilaseca J, et al. Effect of short-term octreotide therapy and total parenteral nutrition on the development of biliary sludge and lithiasis. Hepatogastroenterology 2002;49:609-612. (Pubitemid 34615309)
134. Angelico M, Della Guardia P. Review article: Hepatobiliary complications associated with total parenteral nutrition. Aliment Pharmacol Ther 2000;14 Suppl 2:54-57. (Pubitemid 30349082)
135. Messing B, Bories C, Kunstlinger F, Bernier JJ. Does total parenteral nutrition induce gallbladder sludge formation and lithiasis? Gastroenterology 1983;84(5 Pt 1):1012-1019. (Pubitemid 13119915)
136. Shaffer EA. Gallbladder sludge: What is its clinical significance? Curr Gastroenterol Rep 2001;3:166-173.
137. Diehl AK, Rosenthal M, Hazuda HP, Comeaux PJ, Stern MP. Socioeconomic status and the prevalence of clinical gallbladder disease. J Chronic Dis 1985;38:1019-1026. (Pubitemid 16191171)
138. Sahi T, Paffenbarger RS Jr, Hsieh CC, Lee IM. Body mass index, cigarette smoking, and other characteristics as predictors of selfreported, physician-diagnosed gallbladder disease in male college alumni. Am J Epidemiol 1998;147:644-651. (Pubitemid 28180307)
139. Leitzmann MF, Rimm EB, Willett WC, et al. Recreational physical activity and the risk of cholecystectomy in women. N Engl J Med 1999;341:777-784. (Pubitemid 29420472)
140. Banim PJ, Luben RN, Wareham NJ, Sharp SJ, Khaw KT, Hart AR. Physical activity reduces the risk of symptomatic gallstones: A prospective cohort study. Eur J Gastroenterol Hepatol 2010;22:983-988.
141. Acalovschi M, Badea R, Dumitraçcu D, Varga C. Prevalence of gallstones in liver cirrhosis: A sonographic survey. Am J Gastroenterol 1988;83:954-956.
142. Conte D, Barisani D, Mandelli C, et al. Cholelithiasis in cirrhosis: Analysis of 500 cases. Am J Gastroenterol 1991;86:1629-1632.
143. Conte D, Fraquelli M, Fornari F, Lodi L, Bodini P, Buscarini L. Close relation between cirrhosis and gallstones: Cross-sectional and longitudinal survey. Arch Intern Med 1999;159:49-52. (Pubitemid 29044119)
144. Alvaro D, Angelico M, Gandin C, Ginanni Corradini S, Capocaccia L. Physico-chemical factors predisposing to pigment gallstone formation in liver cirrhosis. J Hepatol 1990;10:228-234. (Pubitemid 20089166)
145. Loria P, Lonardo A, Lombardini S, et al. Gallstone disease in nonalcoholic fatty liver: Prevalence and associated factors. J Gastroenterol Hepatol 2005;20:1176-1184. (Pubitemid 41602559)
146. Méndez-Sánchez N, Bermejo-Martínez LB, Viñals Y, et al. Serum leptin levels and insulin resistance are associated with gallstone disease in overweight subjects. World J Gastroenterol 2005;11:6182-6187. (Pubitemid 43085062)
147. Chen CH, Huang MH, Yang JC, et al. Prevalence and risk factors of gallstone disease in an adult population of Taiwan: An epidemiological survey. J Gastroenterol Hepatol 2006;21:1737-1743.
148. Acalovschi M, Buzas C, Radu C, Grigorescu M. Hepatitis C virus infection is a risk factor for gallstone disease: A prospective hospital-based study of patients with chronic viral C hepatitis. J Viral Hepat 2009;16:860-866.
149. Whorwell PJ, Hawkins R, Dewbury K, Wright R. Ultrasound survey of gallstones and other hepatobiliary disorders in patients with Crohn's disease. Dig Dis Sci 1984;29:930-933. (Pubitemid 14021797)
150. Hutchinson R, Tyrrell PN, Kumar D, Dunn JA, Li JK, Allan RN. Pathogenesis of gall stones in Crohn's disease: An alternative explanation. Gut 1994;35:94-97. (Pubitemid 24059480)
151. Brink MA, Slors JF, Keulemans YC, et al. Enterohepatic cycling of bilirubin: A putative mechanism for pigment gallstone formation in ileal Crohn's disease. Gastroenterology 1999;116:1420-1427. (Pubitemid 29258891)
152. Lapidus A, Akerlund JE, Einarsson C. Gallbladder bile composition in patients with Crohn's disease. World J Gastroenterol 2006;12:70-74. (Pubitemid 43126086)
153. Vítek L, Carey MC. Enterohepatic cycling of bilirubin as a cause of 'black' pigment gallstones in adult life. Eur J Clin Invest 2003;33:799-810. (Pubitemid 37082867)
154. Apstein MD, Dalecki-Chipperfield K. Spinal cord injury is a risk factor for gallstone disease. Gastroenterology 1987;92:966-968. (Pubitemid 17046314)
155. Rotter KP, Larraín CG. Gallstones in spinal cord injury (SCI): A late medical complication? Spinal Cord 2003;41:105-108. (Pubitemid 36174218)
156. Xia CS, Han YQ, Yang XY, Hong GX. Spinal cord injury and cholelithiasis. Hepatobiliary Pancreat Dis Int 2004;3:595-598.
157. Kennedy TM, Jones RH. Epidemiology of cholecystectomy and irritable bowel syndrome in a UK population. Br J Surg 2000;87:1658-1663.
158. Ros E, Zambon D. Postcholecystectomy symptoms. A prospective study of gall stone patients before and two years after surgery. Gut 1987;28:1500-1504. (Pubitemid 17164086)
159. Creutzfeldt W, Lembcke B, Fölsch UR, Schleser S, Koop I. Effect of somatostatin analogue (SMS 201-995, Sandostatin) on pancreatic secretion in humans. Am J Med 1987;82(5B):49-54.
160. Trendle MC, Moertel CG, Kvols LK. Incidence and morbidity of cholelithiasis in patients receiving chronic octreotide for metastatic carcinoid and malignant islet cell tumors. Cancer 1997;79:830-834. (Pubitemid 27076349)
161. Roti E, Minelli R, Gardini E, et al. Chronic treatment with a long-acting somatostatin analogue in a patient with intestinal carcinoid tumor: Occurrence of cholelithiasis. J Endocrinol Invest 1990;13:69-72. (Pubitemid 20076670)
162. Lopez AJ, O'Keefe P, Morrissey M, Pickleman J. Ceftriaxoneinduced cholelithiasis. Ann Intern Med 1991;115:712-714.
163. Bickford CL, Spencer AP. Biliary sludge and hyperbilirubinemia associated with ceftriaxone in an adult: Case report and review of the literature. Pharmacotherapy 2005;25:1389-1395. (Pubitemid 41407637)
164. Angelin B. Effect of thiazide treatment on biliary lipid composition in healthy volunteers. Eur J Clin Pharmacol 1989;37:95-96. (Pubitemid 19197502)
165. Rosenberg L, Shapiro S, Slone D, Kaufman DW, Miettinen OS, Stolley PD. Thiazides and acute cholecystitis. N Engl J Med 1980;303:546-548. (Pubitemid 10046829)
166. Van der Linden W, Ritter B, Edlund G. Acute cholecystitis and thiazides. Br Med J (Clin Res Ed) 1984;289:654-655. (Pubitemid 14000260)
167. Leitzmann MF, Tsai CJ, Stampfer MJ, Willett WC, Giovannucci E. Thiazide diuretics and the risk of gallbladder disease requiring surgery in women. Arch Intern Med 2005;165:567-573. (Pubitemid 40344390)
168. Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Statin use and the risk of cholecystectomy in women. Gastroenterology 2009;136:1593-1600.
169. St Peter SD, Keckler SJ, Nair A, et al. Laparoscopic cholecystectomy in the pediatric population. J Laparoendosc Adv Surg Tech A 2008;18:127-130. (Pubitemid 351252617)
170. Palasciano G, Portincasa P, Vinciguerra V, et al. Gallstone prevalence and gallbladder volume in children and adolescents: An epidemiological ultrasonographic survey and relationship to body mass index. Am J Gastroenterol 1989;84:1378-1382. (Pubitemid 19282059)
171. Kaechele V, Wabitsch M, Thiere D, et al. Prevalence of gallbladder stone disease in obese children and adolescents: Influence of the degree of obesity, sex, and pubertal development. J Pediatr Gastroenterol Nutr 2006;42:66-70. (Pubitemid 43061012)
172. Kratzer W, Walcher T, Arnold F, et al. Gallstone prevalence and risk factors for gallstone disease in an urban population of children and adolescents. Z Gastroenterol 2010;48:683-687.
173. Bogue CO, Murphy AJ, Gerstle JT, Moineddin R, Daneman A. Risk factors, complications, and outcomes of gallstones in children: A single-center review. J Pediatr Gastroenterol Nutr 2010;50:303-308.
174. Holcomb GW Jr, Holcomb GW 3rd. Cholelithiasis in infants, children, and adolescents. Pediatr Rev 1990;11:268-274.
175. Friesen CA, Roberts CC. Cholelithiasis. Clinical characteristics in children. Case analysis and literature review. Clin Pediatr (Phila) 1989;28:294-298. (Pubitemid 19180436)
176. Waldhausen JH, Benjamin DR. Cholecystectomy is becoming an increasingly common operation in children. Am J Surg 1999;177:364-367. (Pubitemid 29252801)
177. Wesdorp I, Bosman D, de Graaff A, Aronson D, van der Blij F, Taminiau J. Clinical presentations and predisposing factors of cholelithiasis and sludge in children. J Pediatr Gastroenterol Nutr 2000;31:411-417.
178. Kumar R, Nguyen K, Shun A. Gallstones and common bile duct calculi in infancy and childhood. Aust N Z J Surg 2000;70:188-191. (Pubitemid 30196408)
179. Henson DE, Albores-Saavedra J, Corle D. Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates. Cancer 1992;70:1493-1497.
180. Wistuba II, Gazdar AF. Gallbladder cancer: Lessons from a rare tumour. Nat Rev Cancer 2004;4:695-706. (Pubitemid 39215068)
181. Lai CH, Lau WY. Gallbladder cancer: A comprehensive review. Surgeon 2008;6:101-110.
182. Levy AD, Murakata LA, Rohrmann CA Jr. Gallbladder carcinoma: Radiologic-pathologic correlation. Radiographics 2001;21:295-314. (Pubitemid 33707760)
183. Pandey M. Risk factors for gallbladder cancer: A reappraisal. Eur J Cancer Prev 2003;12:15-24. (Pubitemid 36233018)
184. Lazcano-Ponce EC, Miquel JF, Muñoz N, et al. Epidemiology and molecular pathology of gallbladder cancer. CA Cancer J Clin 2001;51:349-364. (Pubitemid 34232782)
185. Randi G, Franceschi S, La Vecchia C. Gallbladder cancer worldwide: Geographical distribution and risk factors. Int J Cancer 2006;118:1591-1602. (Pubitemid 43376420)
186. Andia ME, Hsing AW, Andreotti G, Ferreccio C. Geographic variation of gallbladder cancer mortality and risk factors in Chile: A population-based ecologic study. Int J Cancer 2008;123:1411-1416.
187. Serra I, Calvo A, Csendes A, Sharp A. Gastric and gallbladder carcinoma in Chile: Epidemiological changes and control programs. Rev Med Chil 1989;117:834-836.
188. Hsing AW, Bai Y, Andreotti G, et al. Family history of gallstones and the risk of biliary tract cancer and gallstones: A populationbased study in Shanghai, China. Int J Cancer 2007;121:832-838. (Pubitemid 47106214)
189. Hariharan D, Saied A, Kocher HM. Analysis of mortality rates for gallbladder cancer across the world. HPB (Oxford) 2008;10:327-331.
190. Shrikhande SV, Barreto SG, Singh S, Udwadia TE, Agarwal AK. Cholelithiasis in gallbladder cancer: Coincidence, cofactor, or cause! Eur J Surg Oncol 2010;36:514-519.
191. Diehl AK. Gallstone size and the risk of gallbladder cancer. JAMA 1983;250:2323-2326. (Pubitemid 13019245)
192. Csendes A, Becerra M, Rojas J, Medina E. Number and size of stones in patients with asymptomatic and symptomatic gallstones and gallbladder carcinoma: A prospective study of 592 cases. J Gastrointest Surg 2000;4:481-485.
193. Zatonski WA, Lowenfels AB, Boyle P, et al. Epidemiologic aspects of gallbladder cancer: A case-control study of the SEARCH Program of the International Agency for Research on Cancer. J Natl Cancer Inst 1997;89:1132-1138. (Pubitemid 27337927)
194. Kimura W, Shimada H, Kuroda A, Morioka Y. Carcinoma of the gallbladder and extrahepatic bile duct in autopsy cases of the aged, with special reference to its relationship to gallstones. Am J Gastroenterol 1989;84:386-390. (Pubitemid 19106401)
195. Diehl AK, Beral V. Cholecystectomy and changing mortality from gallbladder cancer. Lancet 1981;2:187-189. (Pubitemid 11085411)
196. Tewari M. Contribution of silent gallstones in gallbladder cancer. J Surg Oncol 2006;93:629-632. (Pubitemid 43855692)
197. Randi G, Franceschi S, La Vecchia C. Gallbladder cancer worldwide: Geographical distribution and risk factors. Int J Cancer 2006;118:1591-1602. (Pubitemid 43376420)
198. Sheth S, Bedford A, Chopra S. Primary gallbladder cancer: Recognition of risk factors and the role of prophylactic cholecystectomy. Am J Gastroenterol 2000;95:1402-1410. (Pubitemid 30396295)
199. Stephen AE, Berger DL. Carcinoma in the porcelain gallbladder: A relationship revisited. Surgery 2001;129:699-703. (Pubitemid 32493672)
200. Berk RN, Armbuster TG, Saltzstein SL. Carcinoma in the porcelain gallbladder. Radiology 1973;106:29-31.
201. Cunningham SC, Alexander HR. Porcelain gallbladder and cancer: Ethnicity explains a discrepant literature? Am J Med 2007;120:e17-e18. (Pubitemid 46483304)
202. Kim JH, Kim WH, Yoo BM, Kim JH, Kim MW. Should we perform surgical management in all patients with suspected porcelain gallbladder? Hepatogastroenterology 2009;56:943-945.
203. Kumar S, Kumar S, Kumar S. Infection as a risk factor for gallbladder cancer. J Surg Oncol 2006;93:633-639. (Pubitemid 43855693)
204. Dutta U, Garg PK, Kumar R, Tandon RK. Typhoid carriers among patients with gallstones are at increased risk for carcinoma of the gallbladder. Am J Gastroenterol 2000;95:784-787. (Pubitemid 30123920)
205. Tewari M, Mishra RR, Shukla HS. Salmonella typhi and gallbladder cancer: Report from an endemic region. Hepatobiliary Pancreat Dis Int 2010;9:524-530.
206. Matsukura N, Yokomuro S, Yamada S, et al. Association between Helicobacter bilis in bile and biliary tract malignancies: H. bilis in bile from Japanese and Thai patients with benign and malignant diseases in the biliary tract. Jpn J Cancer Res 2002;93:842-847.
207. Lewis JT, Talwalkar JA, Rosen CB, Smyrk TC, Abraham SC. Prevalence and risk factors for gallbladder neoplasia in patients with primary sclerosing cholangitis: Evidence for a metaplasiadysplasia-carcinoma sequence. Am J Surg Pathol 2007;31:907-913. (Pubitemid 47165145)
208. Nomura T, Shirai Y, Sandoh N, Nagakura S, Hatakeyama K. Cholangiographic criteria for anomalous union of the pancreatic and biliary ducts. Gastrointest Endosc 2002;55:204-208. (Pubitemid 41115183)
209. Babbitt DP, Starshak RJ, Clemett AR. Choledochal cyst: A concept of etiology. Am J Roentgenol Radium Ther Nucl Med 1973;119:57-62.
210. Kang CM, Kim KS, Choi JS, Lee WJ, Kim BR. Gallbladder carcinoma associated with anomalous pancreaticobiliary duct junction. Can J Gastroenterol 2007;21:383-387. (Pubitemid 47162256)
211. Goldgar DE, Easton DF, Cannon-Albright LA, Skolnick MH. Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands. J Natl Cancer Inst 1994;86:1600-1608. (Pubitemid 24336346)
212. Hemminki K, Li X. Familial liver and gall bladder cancer: A nationwide epidemiological study from Sweden. Gut 2003;52:592-596. (Pubitemid 36363417)
213. Venniyoor A. Cholesterol gallstones and cancer of gallbladder (CAGB): Molecular links. Med Hypotheses 2008;70:646-653. (Pubitemid 351187961)
214. Myers RP, Shaffer EA, Beck PL. Gallbladder polyps: Epidemiology, natural history and management. Can J Gastroenterol 2002;16:187-194. (Pubitemid 34546294)
215. Calle EE, Rodriguez C, Jacobs EJ, et al. The American Cancer Society Cancer Prevention Study II Nutrition Cohort: Rationale, study design, and baseline characteristics. Cancer 2002;94:2490-2501. (Pubitemid 34457132)
216. Larsson SC, Wolk A. Obesity and the risk of gallbladder cancer: A meta-analysis. Br J Cancer 2007;96:1457-1461. (Pubitemid 46685777)
217. Yagyu K, Kikuchi S, Obata Y, et al. Cigarette smoking, alcohol drinking and the risk of gallbladder cancer death: A prospective cohort study in Japan. Int J Cancer 2008;122:924-929.
218. Chow WH, Johansen C, Gridley G, Mellemkjaer L, Olsen JH, Fraumeni JF Jr. Gallstones, cholecystectomy and risk of cancers of the liver, biliary tract and pancreas. Br J Cancer 1999;79:640-644. (Pubitemid 29046249)
219. Ishiguro S, Inoue M, Kurahashi N, Iwasaki M, Sasazuki S, Tsugane S. Risk factors of biliary tract cancer in a large-scale population-based cohort study in Japan (JPHC study); with special focus on cholelithiasis, body mass index, and their effect modification. Cancer Causes Control 2008;19:33-41.
220. Zatonski WA, La Vecchia C, Przewozniak K, Maisonneuve P, Lowenfels AB, Boyle P. Risk factors for gallbladder cancer: A Polish case-control study. Int J Cancer 1992;51:707-711.
221. Khan ZR, Neugut AI, Ahsan H, Chabot JA. Risk factors for biliary tract cancers. Am J Gastroenterol 1999;94:149-152. (Pubitemid 29063459)
222. Hsing AW, Gao YT, Han TQ, et al. Gallstones and the risk of biliary tract cancer: A population-based study in China. Br J Cancer 2007;97:1577-1582. (Pubitemid 350175843)
223. Lowenfels AB, Walker AM, Althaus DP, Townsend G, Domellöf L. Gallstone growth, size, and risk of gallbladder cancer: An interracial study. Int J Epidemiol 1989;18:50-54. (Pubitemid 19128631)
224. Caygill CP, Hill MJ, Braddick M, Sharp JC. Cancer mortality in chronic typhoid and paratyphoid carriers. Lancet 1994;343:83-84. (Pubitemid 24019349)
225. Strom BL, Soloway RD, Rios-Dalenz JL, et al. Risk factors for gallbladder cancer. An international collaborative case-control study. Cancer 1995;76:1747-1756.
226. Murata H, Tsuji S, Tsujii M, et al. Helicobacter bilis infection in biliary tract cancer. Aliment Pharmacol Ther 2004;20 Suppl 1:90-94. (Pubitemid 39120278)